Keywords: GBM، glioblastoma multiforme; TF, transcription factors; GBM, glioblastoma multiforme; OCT, octamer binding transcription factor; TMZ, temozolomide; CSC, cancer stem cells; GSC, GBM stem cell; NSC, neuronal stem cellOctamer-binding transcription factor; Cancer stem cell; Glioblastoma
مقالات ISI GBM، glioblastoma multiforme (ترجمه نشده)
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Keywords: GBM، glioblastoma multiforme; DTI, diffusion tensor imaging; AED, antiepileptic drug; GBM, glioblastoma multiforme; mA, milliamperesAntiepileptic; Awake craniotomy; Anti-convulsant; Seizure; Mapping; Current
Keywords: GBM، glioblastoma multiforme; Convection-enhanced delivery; Perfusion magnetic resonance imaging; TopotecanCED, Convection-enhanced delivery; DCE, Dynamic contrast-enhanced; DSC, Dynamic susceptibility contrast-enhanced; GBM, Glioblastoma multiforme; MGMT, Methylguanine methyltransfer
Keywords: GBM، glioblastoma multiforme; Anaplastic astrocytoma; Glioblastoma; Malignant gliomas; Radiation-induced malignant gliomas; Radiotherapy; ReirradiationALL, Acute lymphoblastic leukemia; GBM, Glioblastoma multiforme; RIMG, Radiation-induced malignant glioma; RT, Radiotherapy
Keywords: GBM، glioblastoma multiforme; EGFR, epidermal growth factor receptor; EGFRvIII, EGFR variant III; GBM, glioblastoma multiforme; PAI-1, plasminogen activator inhibitor 1; PAR (1–4), protease activated receptor (1–4); RAS, rat sarcoma oncogene; SCID, severe combined immunodeficiency (in
Keywords: GBM، glioblastoma multiforme; GBM, Glioblastoma multiforme; Doxo, Doxorubicin; Aldoxo, Aldoxorubicin; HPLC, High-performance liquid chromatography; MTD, Maximum tolerated dose; TMZ, Temozolomide; BBB, Blood-brain barrier
Keywords: GBM، glioblastoma multiforme; BBB, blood brain barrier; GBM, glioblastoma multiforme; NTIRE, Non-thermal irreversible electroporation; MRI, magnetic resonance imaging; BDVs, BBB disruption volumes; ETVs, early tissue response volumes; IRVs, irreversible damage volumes; SIMVs, simulati
Keywords: GBM، glioblastoma multiforme; Cerebral tumor; cioUS; Extent of resection; Glioma; High frequency ultrasound imaging; iMRI; lioUS; Ultrasound3D, 3-dimensional; cioUS, Conventional intraoperative ultrasound; EoR, Extend of resection; GBM, Glioblastoma multiforme; GTR, Gross total resect
Keywords: GBM، glioblastoma multiforme; 5-ALA; Fluorescein; Fluorescence-guided resection; Malignant gliomas; Neurosurgical procedures5-ALA, 5-Aminolevulinic acid; EOR, Extent of resection; FLIM, Fluorescence lifetime imaging microscopy; GBM, Glioblastoma multiforme; GTRL, Gross total resection
Keywords: GBM، glioblastoma multiforme; PTX, paclitaxel; SLN, solid lipid nanoparticles; BA, behenic acid; ST, stearylamine; GCS, glycol chitosan; BBB, blood–brain barrier; GBM, glioblastoma multiforme; CNS, central nervous system; NP, nanoparticles; CBSA, cationic bovine serum albumin; NHEJ, n
Keywords: GBM، glioblastoma multiforme; CNS, central nervous system; GBM, glioblastoma multiforme; H&E, hematoxylin and eosinCentral nervous system; Tumor; Cytology; Frozen section; Intraoperative diagnosis
Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment
Keywords: GBM، glioblastoma multiforme; TMZ, temozolomide; HIF-1α, hypoxia inducible factor 1α; MTT, 3-(4,5-cimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; MGMT, O6-methylguanine DNA methyltransferase; PFS, progression-free-survival; GBM, glioblastoma multiforme; HREs, hypoxia response
RGD peptide conjugation results in enhanced antitumor activity of PD0325901 against glioblastoma by both tumor-targeting delivery and combination therapy
Keywords: GBM، glioblastoma multiforme; PD0325901 (PubChem CID: 9826528)CNS, central nervous system; GBM, glioblastoma multiforme; BBB, blood-brain-barrier; ECM, extracellular matrix; RTK, receptor tyrosine kinases; EGFR, epidermal growth factor receptor; PDGFR, platelet-derived growth factor r
New insights into the anticancer activity of carnosol: p53 reactivation in the U87MG human glioblastoma cell line
Keywords: GBM، glioblastoma multiforme; GBM, glioblastoma multiforme; TMZ, temozolomide; CAR, carnosol; MDM2, mouse double minute 2; CHX, cycloheximideDiterpene; Carnosol; Glioblastoma multiforme; p53; Temozolomide
IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme
Keywords: GBM، glioblastoma multiforme; GBM, glioblastoma multiforme; IDH1, isocitrate dehydrogenase 1; MGMT, O6-methylguanine-DNA methyltransferase; MS-HRM, methylation sensitive high resolution melting; MS-MLPA, methylation sensitive multiplex ligation-dependent probe amplification; pGBMs, pr
High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes
Keywords: GBM، glioblastoma multiforme; FZD, Frizzled; GFAP, glial fibrillary acidic protein; GBM, glioblastoma multiforme; HLA, human leukocyte antigens; IBA-1, ionized calcium-binding adapter molecule 1; MHCII, major histocompatibility complex II; TCGA, The Cancer Genome Atlas; TMA, tissue mi
Inhibition of RNA transportation induces glioma cell apoptosis via downregulation of RanGAP1 expression
Keywords: GBM، glioblastoma multiforme; BBB, blood–brain barrier; DAPI, 4′,6-diamidino-2-phenylindole; ERK, extracellular signal-regulated kinase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GBM, glioblastoma multiforme; HRP, horseradish peroxidase; IB, immunoblotting; IgG, immunoglobulin
Development of resistance to antiglioma agents in rat C6 cells caused collateral sensitivity to doxorubicin
Keywords: GBM، glioblastoma multiforme; GBM, glioblastoma multiforme; MDR, multidrug resistance; BCNU, 1,3-Bis(2-chloroethyl)-1-nitrosourea; ROS, reactive oxygen species; NF-kB, nuclear factor kappa-light-chain-enhancer of activated B cells; Nrf2, nuclear factor (erythroid-derived 2)-like 2; HI
Secretory prostate apoptosis response (Par)-4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen-induced cell death
Keywords: GBM، glioblastoma multiforme; CM, conditioned medium; GBM, glioblastoma multiforme; LGG, low grade gliomas; MCS, multicellular spheroids; TAM, tamoxifen; TCGA, The Cancer Genome AtlasGlioblastoma; Par-4; Drug resistance; Multicellular spheroids (MCS); Tamoxifen; Cytotoxicity
The emerging role of tumor-suppressive microRNA-218 in targeting glioblastoma stemness
Keywords: GBM، glioblastoma multiforme; GBM, glioblastoma multiforme; NSC, neural stem cell; CAMTA1, calmodulin-binding transcription activator 1; CDK, cyclin-dependent kinases; NF-κB, nuclear factor-kappa B; VOPP1, vesicular, over-expressed in cancer, prosurvival protein 1; PcG, Polycomb group
Tumor suppressive miRNA-34a suppresses cell proliferation and tumor growth of glioma stem cells by targeting Akt and Wnt signaling pathways
Keywords: GBM، glioblastoma multiforme; bFGF, basic fibroblast growth factor; CNS, central nervous system; EGF, epidermal growth factor; EMT, epithelial–mesenchymal transition; EV, empty vector; GBM, glioblastoma multiforme; GIC, glioma initiating cell; GSC, glioma stem cell; GSK-3β, glycogen s
Angiopoietins as promising biomarkers and potential therapeutic targets in brain injury
Keywords: GBM، glioblastoma multiforme; ALI, acute lung injury; ALS, amyotrophic lateral sclerosis; Ang-1, Angiopoietin-1; Ang-2, Angiopoietin-2; APACHE, acute physiology and chronic health evaluation; BBB, blood–brain barrier; EPO, erythropoietin; GBM, glioblastoma multiforme; ICH, intracrania
Clinical Outcomes of Gamma Knife Radiosurgery in the Salvage Treatment of Patients with Recurrent High-Grade Glioma
Keywords: GBM، glioblastoma multiforme; Anaplastic astrocytoma; Gamma knife; Glioblastoma multiforme; High-grade glioma; Stereotactic radiosurgeryEBRT, External beam radiation therapy; GBM, Glioblastoma multiforme; GKRS, Gamma knife radiosurgery; HGG, High-grade glioma; KPS, Karnofsky performan
The CXCL16–CXCR6 chemokine axis in glial tumors
Keywords: GBM، glioblastoma multiforme; bFGF, FGF-2, basic fibroblast growth factor; DMEM, Dulbecco's modified Eagle's medium; EGF, epidermal growth factor; ES, embryonic stem cell; FCS, fetal calf serum; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GBM, glioblastoma multiforme; GFAP, glial
Luteolin inhibits proliferation of human glioblastoma cells via induction of cell cycle arrest and apoptosis
Keywords: GBM، glioblastoma multiforme; BCNU, 1,3-bis(2-chloroethyl)-1-nitrosourea; CDK, cyclin-dependent kinase; EA, ethyl acetate; FBS, fetal bovine serum; FITC, annexin-V-fluorescein isothiocyanate; GBM, Glioblastoma multiforme; PARP, poly-ADP-ribose polymerase; PBS, phosphate buffered salin
Alternative mechanisms of telomere lengthening: Permissive mutations, DNA repair proteins and tumorigenic progression
Keywords: GBM، glioblastoma multiforme; ALT, alternative lengthening of telomeres; APB, ALT-associated PML body; ECTR, extrachromosomal telomere repeat; GBM, glioblastoma multiforme; MEN1, multiple endocrine neoplasia type 1; MRN, MRE11/RAD50/NBS1; PanNET, pancreatic neuroendocrine tumor; TIF,
Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells
Keywords: GBM، glioblastoma multiforme; CACNA1C, L-type channel subunit Cav1.2; CACNA1G, T-type channel subunit Cav3.1; CACNA1H, T-type channel subunit Cav3.2; GBM, glioblastoma multiforme; LVCC, low voltage gated calcium channelT-type calcium channels; Apoptosis; Glioblastoma multiforme; Akt;
Intra-Arterial Delivery of Bevacizumab after Blood-Brain Barrier Disruption for the Treatment of Recurrent Glioblastoma: Progression-Free Survival and Overall Survival
Keywords: GBM، glioblastoma multiforme; Bevacizumab; Glioblastoma; Intra-arterial chemotherapy; Overall survival; Progression-free survivalBBBD, Blood-brain barrier disruption; BV, Bevacizumab; FLAIR, Fluid attenuated inversion recovery; GBM, Glioblastoma multiforme; IA, Intra-arterial; IV, Int
Adjuvant Immunotherapy with Whole-Cell Lysate Dendritic Cells Vaccine for Glioblastoma Multiforme: A Phase II Clinical Trial
Keywords: GBM، glioblastoma multiforme; Dendritic cells; Glioblastoma multiforme; Immunotherapy; Overall survival; Progression-free survival; VaccineCCRT, Combined chemotherapy and radiotherapy; DC, Dendritic cell; GBM, Glioblastoma multiforme; KPS, Karnofsky Performance Scale; MGMT, Methyl-gua
Hypericin for visualization of high grade gliomas: First clinical experience
Keywords: GBM، glioblastoma multiforme; Hypericin; Photodiagnosis; PD; Glioblastoma; Brain tumor visualization5-ALA induced PpIX, 5-aminolevulinic acid induced protoporphyrin IX; GBM, glioblastoma multiforme; GTR, gross total resection; ICU, intensive care unit; IOM, intraoperative electrophysi
Transforming growth factor (TGF)-β expression and activation mechanisms as potential targets for anti-tumor therapy and tumor imaging
Keywords: GBM، glioblastoma multiforme; AA, Anaplastic astrocytoma; GBM, Glioblastoma multiforme; HER2, Human epidermal growth factor receptor 2; LAP, Latency associated protein; LTBP, Latent TGF-β binding protein; MMP, Matrix metalloproteinases; NSCL, Non-small-cell lung cancer; PET, Positron
Netrin-4 Promotes Glioblastoma Cell Proliferation through Integrin β4 Signaling 12
Keywords: GBM، glioblastoma multiforme; AKT, serine/threonine-protein kinase akt (protein kinase B); DCC, netrin receptor deleted in colorectal cancer; GBM, glioblastoma multiforme; ITGB4, integrin β4; mTOR, mammalian target of rapamycin; NTN, netrin; Q-RT-PCR, quantitative real-time polymerase
O6-Methylguanine-DNA methyltransferase in glioma therapy: Promise and problems
Keywords: GBM، glioblastoma multiforme; BCNU, 1,3-bis(2-chloroethyl)-1-nitrosourea, carmustine; CCNU, 3-(2-chloroethyl)-3-cyclohexyl-1-nitrosouea, lomustine; GBM, glioblastoma multiforme; IHC, immunohistochemistry; MGMT, O6-methylguanine-DNA methyltransferase; MSP, methylation-specific PCR; PCV
Gamma Knife Surgery versus Reoperation for Recurrent Glioblastoma Multiforme
Keywords: GBM، glioblastoma multiforme; Gamma knife surgery; Glioblastoma multiforme; Operation; Stereotactic radiosurgery; Tumor recurrenceCI, Confidence interval; EBRT, External beam radiation therapy; GBM, Glioblastoma multiforme; GKS, Gamma knife surgery; HR, Hazard ratio; KPS, Karnofsky pe
Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy
Keywords: GBM، glioblastoma multiforme; 3-MA, 3-methyladenine; AC, ammonium chloride; BAF, bafilomycin A1; CQ, chloroquine; DCFH-DA, 2,7-dihydrodichlorofluorescein diacetate; DHR123, dihydrorhodamine 123; ERK, extracellular signal-regulated kinase; GBM, glioblastoma multiforme; HEt, dihydroethi
Resveratrol induces cellular senescence with attenuated mono-ubiquitination of histone H2B in glioma cells
Keywords: GBM، glioblastoma multiforme; RV, resveratrol; uH2B, mono-ubiquitinated histone H2B; GBM, glioblastoma multiforme; SA-β-gal, senescence-associated-β-galactosidaseResveratrol; Glioma; Cellular senescence; Mono-ubiquitinated histone H2B; RNF20; Histone modifications
Concomitant Presentation of a Glioblastoma Multiforme With Superimposed Abscess
Keywords: GBM، glioblastoma multiforme; Abscess; Brain; Glioblastoma; Glioma; Intratumoral; MalignancyCT, Computed tomography; GBM, Glioblastoma multiforme; MRI, Magnetic resonance imaging
Targeting the erythropoietin receptor on glioma cells reduces tumour growth
Keywords: GBM، glioblastoma multiforme; EPO, Erythropoietin; EPOR, Erythropoietin receptor; ERK, Extracellular signal-regulated kinases; EPOR-F, Full-length form of EPOR; EPOR-T, Truncated form of EPOR; sEPOR, soluble form of EPOR; GBM, Glioblastoma Multiforme; shRNA, short hairpin RNA; MRI, Ma
Technical advancement in regulatory T cell isolation and characterization using CD127 expression in patients with malignant glioma treated with autologous dendritic cell vaccination
Keywords: GBM، glioblastoma multiforme; BSA, bovine serum albumin; 95% c.i., 95% confidence interval; cpm, counts per minute; DC, dendritic cell; DMSO, dimethylsulfoxide; FACS, fluorescence-activated cell sorting; Foxp3, forkhead box p3; GBM, glioblastoma multiforme; HC, healthy control; HGG, h
Notch- and vitamin D signaling in 1,25(OH)2D3-resistant glioblastoma multiforme (GBM) cell lines
Keywords: GBM، glioblastoma multiforme; 5-aza, 5-azacytidine; Dll, Delta-like; 1,25(OH)2D3, 1,25-dihydroxyvitamin D3; DNMTI, DNA-methyltransferase inhibitor; GBM, glioblastoma multiforme; HDACI, histone deacetylase inhibitor; jag, Jagged; PCR, polymerase chain reaction; TSA, trichostatin ANotch
WHO grade-specific comparative genomic hybridization pattern of astrocytoma – A meta-analysis
Keywords: GBM، glioblastoma multiforme; CGH, comparative genomic hybridization; GBM, glioblastoma multiforme; GTG, G-bands by trypsin using Giemsa; WHO, World Health OrganizationAstrocytoma; Glioblastoma multiforme; Comparative genomic hybridization; CGH; Meta-analysis
Evaluating the prognostic factors effective on the outcome of patients with glioblastoma multiformis: does maximal resection of the tumor lengthen the median survival?
Keywords: GBM، glioblastoma multiforme; CNS, central nervous system; CTR, controlled trial; ETR, extent of tumor resection; GBM, glioblastoma multiforme; GCS, Glasgow Coma Scale; ICU, intensive care unit; KPS, Karnofsky performance score; MRI, magnetic resonance imaging; RT, radiotherapy; TUMS,
Expression of focal adhesion kinase and phosphorylated focal adhesion kinase in human gliomas is associated with unfavorable overall survival
Keywords: GBM، glioblastoma multiforme; ECM, extracelluar matrix; FAK, focal adhesion kinase; GBM, glioblastoma multiforme; GPNMB, glycoprotein nonmetastatic melanoma protein B; GST, glutathione S-transferase; KPS, Karnofsky performance scale; MAPK, mitogen-activated protein kinase; WHO, World
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma
Keywords: GBM، glioblastoma multiforme; metalloproteinase inhibitor; temozolomide; multitarget therapy; glioma; invasivenessDMSO, dimethyl sulfoxide; ECM, extracellular matrix; ELISA, enzyme-linked immunosorbent assay; FBS, fetal bovine serum; GBM, glioblastoma multiforme; MMP, matrix metallopr
Rapid malignant transformation of low-grade astrocytomas: report of 2 cases and review of the literature
Keywords: GBM، glioblastoma multiforme; CT, computed tomography; EGFR, epidermal growth factor receptor; FLAIR, fluid-attenuated inversion recovery; GBM, glioblastoma multiforme; MRI, magnetic resonance imagingLow-grade glioma; Malignant transformation; High-grade glioma; Glioblastoma; Histopat
CX3CR1 promotes recruitment of human glioma-infiltrating microglia/macrophages (GIMs)
Keywords: GBM، glioblastoma multiforme; AC, astrocytoma; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GBM, glioblastoma multiforme; GFAP, glial fibrillary acidic protein; GIM, glioma-infiltrating microglia/macrophages; Iba1, ionized calcium-binding adapter molecule 1; MMP, matrix metallopro
Glioma proteomics: Status and perspectives
Keywords: GBM، glioblastoma multiforme; CSF, cerebrospinal fluid; CNS, central nervous system; GBM, glioblastoma multiforme; 2DE, two-dimensional gel electrophoresis; WB, Western blot; IHC, immunohistochemistry; PMF, peptide mass fingerprint; 2D-DIGE, 2 dimensional differential gel electrophore
MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme
Keywords: GBM، glioblastoma multiforme; GBM, glioblastoma multiforme; BCNU, 1,3-bis(2-chloroethyl)-1-nitrosourea; UTR, untranslated region; LRRFIP1, leucine rich repeat (in FLII) interacting protein 1; TNFR, tumor necrosis factor receptor; TRAF, TNFR-associated factor; TRIP, TRAF-interacting pr
CXCR4 mediates the proliferation of glioblastoma progenitor cells
Keywords: GBM، glioblastoma multiforme; GBM, glioblastoma multiforme; GDS, glioma-derived spheres; CSC, cancer stem cellsBrain tumor(s); Glioma(s); Cancer stem cell(s); CXCR4
IQGAP1 regulation and roles in cancer
Keywords: GBM، glioblastoma multiforme; APC, adenomatous polyposis coli; Arp2/3, actin related protein; EGF, epidermal growth factor; EMT, epithelial-to-mesenchymal transition; ERK, extracellular signal-regulated kinase; GBM, glioblastoma multiforme; GAP, GTPase-activating protein; HCC, hepatoc