Keywords: مرکز ژرمینال; Ectopic lymphoid tissue; immunoglobulin; lymphoid aggregate; lymphorganogenesis; AID; Activation-induced cytidine deaminase; BAFF; B cell-activating factor of the TNF family; Bcl; B-cell lymphoma; CD21L; CD21 ligand; CRSsNP; Chronic rhinosinusitis witho
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Keywords: مرکز ژرمینال; DCs; dendritic cells; FAE; follicle-associated epithelia; GALT; gut-associated lymphatic tissues; GC; germinal center; GIT; gastrointestinal tract; GMs; glucan microparticles; GRAS; generally recognized as safe; HPV; human papilloma virus; IBD; inflammato
Keywords: مرکز ژرمینال; AD; atopic dermatitis; CSR; class-switch recombination; CXCR5; chemokine (C-X-C motif) receptor type 5; DCs; dendritic cells; DEHP; di-(2-ethylhexyl)phthalate; FFPE; formalin-fixed paraffin-embedded; GC; germinal center; ICOS; inducible T cell co-stimulat
Keywords: مرکز ژرمینال; germinal center; immune activation; immunohistochemistry; inflammation; nerve fibers; NGF; NF2F11; PGP9.5; vestibulodynia; vulvar pain; vulvar vestibulitis; vulvodynia;
Keywords: مرکز ژرمینال; Germinal center; Hodgkin lymphoma; LP cell
Keywords: مرکز ژرمینال; MG; myasthenia gravis; EBV; Epstein-Barr virus; TLR; Toll-like receptor; GC; germinal center; IFN; interferon; AChR; acetylcholine receptor; EBER; EBV-encoded small RNA; LCM; laser-capture microdissection; IRF8; interferon regulatory factor 8; LMP1; Eps
Keywords: مرکز ژرمینال; Follicular dendritic cell; germinal center; antigen presentation; follicular dendritic cell sarcoma; Castleman’s disease
Keywords: مرکز ژرمینال; Micelle-based vaccine; Adjuvant; Immune response; Germinal center
Keywords: مرکز ژرمینال; humoral immunity; vaccination; regulatory T cells; Tfr; Tfh; germinal center
Keywords: مرکز ژرمینال; Epigenetic dynamics; Immune system; Autoimmune diseases; DNA methylation; Histone modifications; DNMT; DNA methyltransferase; TET; ten-eleven translocation; AID/AICDA; activation-induced cytidine deaminase; APOBEC; Apolipoprotein B mRNA editing enzyme; BE
Keywords: مرکز ژرمینال; Liposome vaccine; Lymphatic targeting; Immunological memory; Germinal center; Follicular T helper cells;
Keywords: مرکز ژرمینال; follicular dendritic cells; fibroblastic reticular cells; secondary lymphoid organs; tertiary lymphoid tissues; germinal center; lymphoid organogenesis
Keywords: مرکز ژرمینال; AFC; antibody-forming cells; BM; bone marrow; CGG; chicken γ-globulin; GC; germinal center; LDH; lactose dehydrogenase; NP; (4-hydroxy-3-nitrophenyl)-acetyl; NIP; (4-hydroxy-5-iodo-3-nitrophenyl) acetyl; Ova; ovalbumin; rPA; recombinant protective antige
A novel mouse model for tracking the fate of CXCR5-expressing T cells
Keywords: مرکز ژرمینال; Follicular helper T cells; CXCR5; Memory T cells; Humoral immunity; GC; Germinal center; Tfh; Follicular helper T; OVA; Ovalbumin; CXC-R5; C-X-C chemokine receptor type 5; CCR7; C-C chemokine receptor type 7; ICOS; Inducible costimulator; PD-1; Programmed
Pathogenic and protective roles of B cells and antibodies in patients with chronic rhinosinusitis
Keywords: مرکز ژرمینال; Antibodies; antibody deficiency; autoimmunity; chronic rhinosinusitis; B cells; immunodeficiency; mucosal immunity; BAFF; B-cell activating factor of the TNF family; BAFF-R; B-cell activating factor of the TNF family receptor; CRS; Chronic rhinosinusitis;
Regulation of B cell fate, survival, and function by mitochondria and autophagy
Keywords: مرکز ژرمینال; Mitochondria; Germinal center; B cells; Plasma cells; Memory B cells; ROS; Metabolism; Autophagy; Mitophagy;
External signals regulate germinal center fate-determining transcription factors in the A20 lymphoma cell line
Keywords: مرکز ژرمینال; A20 cell line; Germinal center; BCL6; FBXO11; CD40; IRF4;
Dual-route targeted vaccine protects efficiently against botulinum neurotoxin A complex
Keywords: مرکز ژرمینال; BoNT; clostridium botulinum neurotoxin; DCpep; dendritic cell binding peptide; Hc; heavy chain of BoNT/A; CL; colon; MLN; mesenteric lymph node; SP; spleen; PLN; peripheral lymph node; GC; germinal center; Tfh; T follicular helper cells; Botulinum neuroto
Co-delivery of a CD4 T cell helper epitope via covalent liposome attachment with a surface-arrayed B cell target antigen fosters higher affinity antibody responses
Keywords: مرکز ژرمینال; Antibody response; Subunit vaccine; T cell help; Liposome; Vaccine delivery; Helper peptide; LLPC; Long-lived plasma cell; sLACK; liposomes packaged with free LACK peptide; pLACK; liposomes packaged with palmitoylated LACK peptide; iLN; inguinal lymph nod
Dysregulated Response of Follicular Helper T Cells to Hepatitis B Surface Antigen Promotes HBV Persistence in Mice and Associates With Outcomes of Patients
Keywords: مرکز ژرمینال; Viral Hepatitis; Immune Regulation; Neutralizing Antibody Response; Immunotherapy; ADCC; antibody-dependent cell-mediated cytotoxicity; anti-HBs; antibodies specific for hepatitis B surface antigen; ASC; antibody-secreting cell; CHB; chronic hepatitis B;
miRNA meets plasma cells “How tiny RNAs control antibody responses”
Keywords: مرکز ژرمینال; PC; plasma cell; PB; plasmablast; GC; germinal center; SHM; somatic hypermutation; CSR; class switch recombination; AID; activation-induced cytidine deaminase; Ig; immunoglobulin; Blimp-1; B-lymphocyte-induced maturation protein 1; DGCR8; DiGeorge syndrom
Airway exposure initiates peanut allergy by involving the IL-1 pathway and T follicular helper cells in mice
Keywords: مرکز ژرمینال; Follicular T cells; IL-4; IgE; allergy; peanut; IL-1; IL-33; BAL; Bronchoalveolar lavage; CTX; Cholera toxin; eGFP; Enhanced green fluorescent protein; FACS; Fluorescence-activated cell sorting; GC; Germinal center; IL-1RAcP; IL-1R-associated protein; IN;
Tumor necrosis factor superfamily member (TNFSF) 13 (APRIL) and TNFSF13B (BAFF) downregulate homeostatic immunoglobulin production in the intestines
Keywords: مرکز ژرمینال; Ab; antibody; APRIL; a proliferation-inducing ligand; BAFF; B-cell activating factor belonging to the tumor necrosis factor family; BCMA; B cell maturation antigen; CFSE; carboxyfluorescein diacetate succinimidyl ester; CSR; class switch recombination; DC
The TH1 phenotype of follicular helper T cells indicates an IFN-γ-associated immune dysregulation in patients with CD21low common variable immunodeficiency
Keywords: مرکز ژرمینال; Follicular helper T cells; common variable immunodeficiency; IFN-γ; germinal center; CD21low B cells; T-bet; CT; Computed tomography; cTFH; Circulating follicular T helper; CVID; Common variable immunodeficiency; CVIDc; Complex common variable immunodefi
Induction of plasmablasts by follicular helper T cell-CXCL13 axis upon occurrence of herpes zoster
Keywords: مرکز ژرمینال; Herpes zoster; Plasmablast; Follicular helper T cell; CXCL13; Varicella zoster virus; APC; Allophycocyanin; CBA; Cytometric bead array; cTfh; Circulating T follicular helper; DENV; Dengue virus; ELISA; Enzyme-linked immunosorbent assay; FITC; Fluorescein
Cytokines as therapeutic targets in primary Sjögren syndrome
Keywords: مرکز ژرمینال; APC; antigen-presenting cells; APRIL; a proliferation-inducing ligand; Auto-Ab; autoantibodies; BAFF; B-cell activating factor; BCR; B-cell receptor; Bm; mature B cell; BR3; B-cell activating factor receptor 3; DC; dendritic cell; FDC; follicular dendriti
B cell depleting therapy regulates splenic and circulating T follicular helper cells in immune thrombocytopenia
Keywords: مرکز ژرمینال; Immune thrombocytopenia; T follicular helper cells; Rituximab; ADCC; antibody-dependent cell-mediated cytotoxicity; AID; autoimmune diseases; FC; fold change; GC; germinal center; ITP; immune thrombocytopenia; PBMC; peripheral blood mononuclear cells; PBL
Long-term humoral immunity induced by CVC1302-adjuvanted serotype O foot-and-mouth disease inactivated vaccine correlates with promoted T follicular helper cells and thus germinal center responses in mice
Keywords: مرکز ژرمینال; FMDV; CVC1302; Long-term humoral response; Germinal center; T follicular helper cell;
Vaccination of rhesus macaques with the live-attenuated HSV-1 vaccine VC2 stimulates the proliferation of mucosal T cells and germinal center responses resulting in sustained production of highly neutralizing antibodies
Keywords: مرکز ژرمینال; Herpes simplex; Vaccine; Live-attenuated; Germinal center; B cell; T cell; Rhesus macaques; Neutralizing antibodies; Humoral immunity; Cellular immunity;
Beta2 integrins are required for follicular helper T cell differentiation in humans
Keywords: مرکز ژرمینال; LAD-1; CD18 deficiency; Beta2 integrins; CD18; Follicular helper T cells (Tfh); Follicular regulatory T cells (Tfr); LAD-1; leukocyte adhesion deficiency syndrome type 1; Tfh; follicular helper T cells; Tfr; follicular regulatory T cells; Tr; regulatory T
Incorporation of a bi-functional protein FimH enhances the immunoprotection of chitosan-pVP1 vaccine against coxsackievirus B3-induced myocarditis
Keywords: مرکز ژرمینال; Coxsackievirus B3; M cell-targeting; Mucosal adjuvant; Mucosal vaccine; CVB3; coxsackievirus B3; MLN; mesenteric lymph node; TLR; toll like receptor; M cell; Microfold cell; GP2; glycoprotein 2; APCs; antigen-presenting cells; GC; germinal center; PPs; pe
CD11b regulates antibody class switching via induction of AID
Keywords: مرکز ژرمینال; ITGAM; integrin subunit alpha M; SLE; systemic lupus erythematosus; CSR; class switch recombination; AID; activation induced cytidine deaminase; TLR; Toll-like receptor; BCR; B cell receptors; SHM; somatic hypermutation; CFSE; carboxyfluorescein succinimi
Regulatory B cells in rheumatoid arthritis: Alterations in patients receiving anti-TNF therapy
Keywords: مرکز ژرمینال; ACPA; anti-citrullinated protein antibody; B10; IL-10 producing regulatory B cells; Bregs; regulatory B cells; CCP; cyclic citrullinated peptide specific antibody; CRP; C reactive protein; DAS; disease activity score; DMARD; disease-modifying anti-rheumat
Critical Role for Skin-Derived Migratory DCs and Langerhans Cells in TFH and GC Responses after Intradermal Immunization
Keywords: مرکز ژرمینال; DC; dendritic cell; dDC; dermal dendritic cell; DLN; draining lymph node; DT; diphtheria toxin; EC; ear cut; GC; germinal center; ID; intradermal; LC; Langerhans cell; LN; lymph node; NP; poly-lactic acid nanoparticle; PBS; phosphate buffered saline; PLA;
Pregnancy favors the expansion of circulating functional follicular helper T Cells
Keywords: مرکز ژرمینال; Bcl-6; transcription factor B cell lymphoma-6; CMV; cytomegalovirus; E2-17β; estradiol; ELISA; Enzyme-linked immunosorbent assay; GC; germinal center; HbsAg; hepatitis B superficial antigen; HBV; hepatitis B virus; HIV; Human immunodeficiency virus; IC
Molecular analysis of immunoglobulin variable genes supports a germinal center experienced normal counterpart in primary cutaneous diffuse large B-cell lymphoma, leg-type
Keywords: مرکز ژرمینال; AB; activated B-cell; GC; germinal center; DLBCL; diffuse large B-cell lymphoma; IGV; immunoglobulin variable gene (IGHVheavy chain, IGLVlight chain); PCDLBCL-LT; primary cutaneous diffuse large B-cell lymphoma, leg type; SpA; staphylococcal protein A; Pr
Vaccine nanocarriers: Coupling intracellular pathways and cellular biodistribution to control CD4 vs CD8 T cell responses
Keywords: مرکز ژرمینال; Vaccine design; Antigen presentation; T follicular helper cells; Germinal center; Dendritic cells;
Lifelong memory responses perpetuate humoral TH2 immunity and anaphylaxis in food allergy
Keywords: مرکز ژرمینال; IgE; mast cells; memory B cells; plasma cells; TH2; food allergy; anaphylaxis; IgG1; peanut allergy; germinal centers; APC; Allophycocyanin; BM; Bone marrow; BZ; Bortezomib; CD40L; CD40 ligand; CFSE; Carboxyfluorescein succinimidyl ester; CYC; Cyclophosph
Maternal T and B cell engraftment in two cases of X-linked severe combined immunodeficiency with IgG1 gammopathy
Keywords: مرکز ژرمینال; AUC; area under the curve; BCR; B cell receptor; γc; common gamma chain; CBT; cord blood transplantation; CDR1; complementarity determining region 1; CSR; class-switch recombination; ddPCR; droplet digital polymerase chain reaction; FACS; fluorescence ac
CD11c+ T-bet+ memory B cells: Immune maintenance during chronic infection and inflammation?
Keywords: مرکز ژرمینال; ABCs; Age-related B cells; AID; activation-induced cytidine deaminase; BCR; B cell receptor; DT; diphtheria toxin; EMLA; E. muris-like agent; FcR; Fc receptor; GC; germinal center; HCl; hairy cell leukemia; IOE; Ixodes ovatus ehrlichia; LPS; lipopolysacch
Human regulatory B cells control the TFH cell response
Keywords: مرکز ژرمینال; Regulatory B cells; follicular T helper cells; IL-12; IL-21; antibody production; humoral immune response; Bcl-6; B-cell lymphoma 6; Breg; Regulatory B; DC; Dendritic cell; Foxp3; Forkhead box P3; GC; Germinal center; ICAM; Intercellular adhesion molecule
Insight into pathogenesis of Sjögren's syndrome: Dissection on autoimmune infiltrates and epithelial cells
Keywords: مرکز ژرمینال; SS; Sjögren's syndrome; DC; dendritic cells; pDC; plasmacytoid dendritic cells; NK; natural-killer cells; GC; germinal center; MSG; minor salivary gland; SGEC; salivary gland epithelial cells; Sjögren's syndrome; Infiltrates; Salivary gland epithelial c
Follicular helper T cells mediate IgE antibody response to airborne allergens
Keywords: مرکز ژرمینال; Follicular T cells; IL-4; IgE; allergy; allergens; TH2 cells; APC; Antigen-presenting cell; BAL; Bronchoalveolar lavage; eGFP; Enhanced green fluorescent protein; FACS; Fluorescence-activated cell sorting; GC; Germinal center; HDM; House dust mite; ICOS;
Control of memory B cell responses by extrinsic and intrinsic mechanisms
Keywords: مرکز ژرمینال; Memory B lymphocytes; B cell antigen receptor; Immunoglobulin tail tyrosine; Class-switching; Affinity maturation; Germinal center;
Genetic drivers of NF-κB deregulation in diffuse large B-cell lymphoma
Keywords: مرکز ژرمینال; DLBCL; Germinal center; NF-κB; Genetic lesions;
Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma
Keywords: مرکز ژرمینال; Q; quercetin; BL; Burkitt's lymphoma; BCR; B cell receptor; GC; Germinal Center; EBV; Epstein-Barr virus; PI3K; phosphatidylinositol-3-kinase; AKT; AKT or protein kinase B; mTOR; mammalian target of rapamycin; BEZ235; NVP-BEZ235; I-c-Myc; c-Myc inhibi
Dock10 regulates CD23 expression and sustains B-cell lymphopoiesis in secondary lymphoid tissue
Keywords: مرکز ژرمینال; ANOVA; analysis of variance; BCR; B-cell receptor; BM; bone marrow; CM; complete medium; DN; double negative; DP; double positive; FO; follicular; GC; germinal center; GEF; guanine nucleotide exchange factor; GEP; gene expression profile; IB; isolation bu
Opposing roles of TGF-β in prostaglandin production by human follicular dendritic cell-like cells
Keywords: مرکز ژرمینال; COX; cyclooxygenase; FDC; follicular dendritic cell; GC; germinal center; IL-1Ra; IL-1 receptor antagonist; MAPK; mitogen-activated protein kinase; mPGES-1; microsomal prostaglandin I synthase-1; PG; prostaglandin; Follicular dendritic cell; TGF-β; Prost
Toll-like receptor 3 adjuvant in combination with virus-like particles elicit a humoral response against HIV
Keywords: مرکز ژرمینال; Virus Like Particle (VLP); TLR3; HIV; Neutralizing antibody; Germinal center; Vaccine;
Insights into the development and regulation of T follicular helper cells
Keywords: مرکز ژرمینال; Th; T helper; Tfh; T follicular helper; IL; interleukin; Ig; Immunoglobulin; STAT; signal transduction and activator of transcription; ICOS; inducible co-stimulator; SLAM; signaling lymphocytic activation molecule; SAP; slam associated protein; GC; germin