دانلود مقالات ISI درباره GLP-1، peptide-1 like glucagon + ترجمه فارسی

Two small molecule agonists of glucagon-like peptide-1 receptor modulate the receptor activation response differently

Keywords: GLP-1، peptide-1 like glucagon; GLP-1, glucagon-like peptide-1; GLP-1R, glucagon-like peptide-1 receptorGLP-1; GLP-1R; Compound 2; Compound B; Calcium influx

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Perspective: TGR5 (Gpbar-1) in liver physiology and disease

Keywords: GLP-1، peptide-1 like glucagon; CA, cholic acid; cAMP, cyclic AMP; CBDL, common bile duct ligation; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; eNOS, endothelial nitric oxide synthase; FXR, farnesoid X receptor; GLP-1, glucagon-like peptide-1; HSC, hepatic stellate cells; INT-77

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Intestinal fatty acid infusion modulates food preference as well as calorie intake via the vagal nerve and midbrain–hypothalamic neural pathways in rats

Keywords: GLP-1، peptide-1 like glucagon; AR, adrenergic receptor; ARC, arcuate nucleus; CCK, cholecystokinin; DA, dopamine; DMH, dorsomedial hypothalamus; GLP-1, glucagon-like peptide-1; HCD, high-carbohydrate diet; HFD, high-fat diet; LH, lateral hypothalamus; α-MT, α-methyl-p-tyrosine; NAc, nu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Dipeptidyl peptidase 4 as a therapeutic target in ischemia/reperfusion injury

Keywords: GLP-1، peptide-1 like glucagon; BM, bone marrow; BNP, brain natriuretic peptide; EC, endothelial cell; ERK, extracellular signal regulated kinase; GLP-1, glucagon-like peptide-1; GSK3β, glycogen synthase kinase-β; GLUT, glucose transporter; HIF-1, hypoxia-inducible factor-1; IRI, ischem

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Evaluation of the potential of dietary proteins as precursors of dipeptidyl peptidase (DPP)-IV inhibitors by an in silico approach

Keywords: GLP-1، peptide-1 like glucagon; T2D, type 2 diabetes; DPP-IV, dipeptidyl peptidase (DPP)-IV; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide-1; ACE, angiotensin converting enzyme.Dipeptidyl peptidase (DPP)-IV Inhibitor; In silico analysis; Dietary protein

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2012 سفارش ترجمه

Chronic administration of ezetimibe increases active glucagon-like peptide-1 and improves glycemic control and pancreatic beta cell mass in a rat model of type 2 diabetes

Keywords: GLP-1، peptide-1 like glucagon; ABCG5, ATP binding cassette transporters G5; DPP-4, dipeptidyl peptidase-4; FFA, free fatty acids; GLP-1, glucagon-like peptide-1; NASH, non-alcoholic steatohepatitis; NPC1L1, Niemann-Pick C1-like 1; TC, total cholesterol; TG, triglycerideEzetimibe; Gluca

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Glucagon-like peptide-1 relaxes gastric antrum through nitric oxide in mice

Keywords: GLP-1، peptide-1 like glucagon; GLP-1, glucagon-like peptide-1; GLP-1R, GLP-1 receptor; l-NAME, Nω-nitro-l-arginine methyl ester; NO, nitric oxide; NOS, nitric oxide synthase; TTX, tetrodotoxin; CCh, carbachol; RT-PCR, reverse-transcriptase polymerase chain reactionGlucagon like peptide

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

5-Hydroxy-eicosapentaenoic acid is an endogenous GPR119 agonist and enhances glucose-dependent insulin secretion

Keywords: GLP-1، peptide-1 like glucagon; AA, arachidonic acid; CHO, Chinese hamster ovary; ELISA, enzyme-linked immunosorbent assay; EPA, eicosapentaenoic acid; GLP-1, glucagon-like peptide-1; GPCR, G-protein-coupled receptor; HTB, Hepes Tyrode’s bovine albumin buffer; PCR, polymerase chain reac

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Vildagliptin blocks vascular injury in thoracic aorta of diabetic rats by suppressing advanced glycation end product–receptor axis

Keywords: GLP-1، peptide-1 like glucagon; GLP-1, glucagon-like peptide-1; AGEs, advanced glycation end products; RAGE, receptor for AGEs; VCAM-1, vascular cell adhesion molecule-1; OLETF, ratsOtsuka Long-Evans Tokushima Fatty rats; BSA, bovine serum albumin; Abs, antibodies; PAI-1, plasminogen ac

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Milk signalling in the pathogenesis of type 2 diabetes

Keywords: GLP-1، peptide-1 like glucagon; AA, amino acids; BTC, betacellulin; CCK, cholecystokinin; ER, endoplasmic reticulum; GH, growth hormone; GI, glycaemic index; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide-1; 5-HT, 5-hydroxytryptamine (serotonin); FoxO1,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Coupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: A computational analysis

Keywords: GLP-1، peptide-1 like glucagon; Calcium; cAMP; Exocytosis; Diabetes; Mathematical modelAC, adenylyl cyclase; [Ca2+]c, cytoplasmic Ca2+ concentration; DGP, docked granule pool; EPAC, guanyl exchange proteins; fMF, metabolic activation factor; GLP-1, glucagon-like peptide-1; [Glu], glucos

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of a novel GPR119 agonist, AS1269574, with in vitro and in vivo glucose-stimulated insulin secretion

Keywords: GLP-1، peptide-1 like glucagon; DPP4, dipeptidyl peptidase inhibitor 4; GLP-1, glucagon-like peptide-1; GPCR, G-protein-coupled receptor; GPR119, G-protein-coupled receptor 119; GSIS, glucose-stimulated insulin secretion; RFU, relative fluorescence unit; T2DM, type 2 diabetes mellitusGP

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Glucagon-like peptide-2, but not glucose-dependent insulinotropic polypeptide, stimulates glucagon release in patients with type 1 diabetes

Keywords: GLP-1، peptide-1 like glucagon; ALAT, alanine aminotransferase; ANOVA, analysis of variance; ASAT, aspartate aminotransferase; AUC, area under curve; EDTA, ethylenediaminetetraacetic acid; g, gravity; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide-1; GLP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Pancreatic β-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

Keywords: GLP-1، peptide-1 like glucagon; GLP-1, glucagon-like peptide-1; T2DM, type 2 diabetes mellitus; BG, blood glucose; PG, plasma glucoseAmylin; Proinsulin; C-peptide; Normoglycaemia

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Addition of a cysteine to glucagon-like peptide-1 (GLP-1) conjugates GLP-1 to albumin in serum and prolongs GLP-1 action in vivo

Keywords: GLP-1، peptide-1 like glucagon; GLP-1, glucagon-like peptide-1; mGLP-1, mutated glucagon-like peptide-1; DPPIV, dipeptidyl peptidase IV; IPGTT, intraperitoneal glucose tolerance tests; AUC, area under the curveGlucagon-like peptide-1; Albumin-conjugation; Protease degradation; Diabetic

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

AS1907417, a novel GPR119 agonist, as an insulinotropic and β-cell preservative agent for the treatment of type 2 diabetes

Keywords: GLP-1، peptide-1 like glucagon; DPP4, dipeptidyl peptidase inhibitor 4; GLP-1, glucagon-like peptide-1; GPR119, G-protein-coupled receptor 119; GSIS, glucose-stimulated insulin secretion; HbA1c, hemoglobin A1c; HEK, human embryonic kidney; LPC, lysophosphatidylcholine; OEA, oleoylethano

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Glucagon-Like Peptide-2 Receptor Modulates Islet Adaptation to Metabolic Stress in the ob/ob Mouse

Keywords: GLP-1، peptide-1 like glucagon; Glucagon; GLP-2; Glucagon-Like Peptide-1; GLP-1; Inflammation; IsletsBW, body weight; GIP, glucose-dependent insulinotropic peptide; GLP-1, glucagon-like peptide-1; GLP-1R, glucagon-like peptide-1 receptor; GLP-2, glucagon-like peptide-2; GLP-2R, glucagon

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Pramlintide Lowered Glucose Excursions and Was Well-Tolerated in Adolescents with Type 1 Diabetes: Results from a Randomized, Single-Blind, Placebo-Controlled, Crossover Study

Keywords: GLP-1، peptide-1 like glucagon; AUC, Area under the concentration curve; Cmax, Peak plasma concentration; CI, Confidence interval; CV, Coefficient of variation; CL/F, Apparent clearance; DCCT, Diabetes Control and Complications Trial; GLP-1, Glucagon-like peptide-1; LS, Least squares; S

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Differential effect of PYY1-36 and PYY3-36 on gastric emptying in man

Keywords: GLP-1، peptide-1 like glucagon; AUC, area under the curve; GLP-1, glucagon-like peptide-1; PYY, peptide tyrosine-tyrosine; T50, half-emptying time; VAS, visual analogue scale; Ret120, the percent of radioactivity remaining at 120 minPeptide YY; Gastric emptying; Metabolic control; Nause

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents

Keywords: GLP-1، peptide-1 like glucagon; GLP-1, glucagon-like peptide-1; IGF-1, insulin-like growth factor-1; IPGTT, intraperitoneal glucose tolerance test; ITT, insulin tolerance testApoptosis; Beta-cell; Exendin-4; GLP-1; Proliferation; Diabetes

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Layer and broiler chicks exhibit similar hypothalamic expression of orexigenic neuropeptides but distinct expression of genes related to energy homeostasis and obesity

Keywords: GLP-1، peptide-1 like glucagon; GH, growth hormone; SS, somatostatin; CNS, central nervous system; NPY, neuropeptide Y; ORX, orexin; AGRP, agouti-related protein; POMC, proopiomelanocortin; CRH, corticotropin releasing hormone; GLP-1, glucagon-like peptide-1; ACC, acetyl-CoA carboxylase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Characterizing positive and negative selection and their phylogenetic effects

Keywords: GLP-1، peptide-1 like glucagon; dN, the non-synonymous substitution rate; dS, the synonymous substitution rate; GLP-1, Glucagon-Like Peptide-1; NCBI, National Center for Biotechnology Information (http://www.ncbi.nlm.nih.gov/), houses a reference taxonomy; TAED, The Adaptive Evolution D

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

DPP4 inhibitors for diabetes—What next?

Keywords: GLP-1، peptide-1 like glucagon; BNP, brain-derived natriuretic peptide; DPP, dipeptidyl peptidase; G-CSF, granulocyte-colony stimulating factor; GIP, glucose dependent insulinotropic peptide; GLP-1, glucagon-like peptide-1; HIF-1, hypoxia inducible factor-1; HOMA-β, homeostasis model as

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Impaired energetics in heart failure — A new therapeutic target

Keywords: GLP-1، peptide-1 like glucagon; CPT-1, carnitine palmitoyl transporter 1; ERRα, estrogen-related receptor; FFA, free fatty acid; GIK, glucose- insulin-potassium; GIP, gastric inhibitory peptide; GLP-1, glucagon-like peptide-1; HF, heart failure; INA, late sodium current; MRS, magnetic r

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

An Albumin-Exendin-4 Conjugate Engages Central and Peripheral Circuits Regulating Murine Energy and Glucose Homeostasis

Keywords: GLP-1، peptide-1 like glucagon; DPP-4, dipeptidyl peptidase-4; Ex-4, exendin-4; GLP-1, glucagon-like peptide-1; GLP-1R, GLP-1 receptor; HSA, human serum albumin; T2DM, type 2 diabetes mellitus

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Glucagon Receptor Signaling Is Essential for Control of Murine Hepatocyte Survival

Keywords: GLP-1، peptide-1 like glucagon; BHK, baby hamster kidney; CHX, cycloheximide; DISC, death-inducing signaling complex; Epac, exchange protein directly activated by cyclic AMP; Gcgr, glucagon receptor; GLP-1, glucagon-like peptide-1; GLP-2, glucagon-like peptide-2; PKA, protein kinase A;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Intravenous CCK-8, but not GLP-1, suppresses ghrelin and stimulates PYY release in healthy men

Keywords: GLP-1، peptide-1 like glucagon; CCK, cholecystokinin; GLP-1, glucagon-like peptide-1; PYY, peptide YYCholecystokinin; Glucagon-like peptide-1; Peptide YY; Ghrelin

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Metabolism of glucagon-like peptide-2 in pigs: Role of dipeptidyl peptidase IV

Keywords: GLP-1، peptide-1 like glucagon; ANOVA, analysis of variance; AUC, area under the curve; DPP-IV, dipeptidyl peptidase IV; GLP-1, glucagon-like peptide-1; GLP-2, glucagon-like peptide-2; IR, immunoreactivity; MCR, metabolic clearance rate; RIA, radioimmunoassay; T½, half-life.Valine-pyrro

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Glucagon-like peptide-1 modulates synaptic transmission to identified pancreas-projecting vagal motoneurons

Keywords: GLP-1، peptide-1 like glucagon; EPSC, excitatory postsynaptic current; IPSC, inhibitory postsynaptic current; DMV, dorsal motor nucleus of the vagus; NTS, nucleus tractus solitarius; DVC, dorsal vagal complex; GLP-1, glucagon-like peptide-1; HP, holding potential; TTX, tetrodotoxinBrain

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Drug Treatment of the Overweight Patient

Keywords: GLP-1، peptide-1 like glucagon; BMI, body mass index; CI, confidence interval; FDA, U.S. Food and Drug Administration; GLP-1, Glucagon-like peptide-1; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NPY, neuropeptide Y; RIO, Rimonabant in Obesity

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Biology of Incretins: GLP-1 and GIP

Keywords: GLP-1، peptide-1 like glucagon; DPP-4, dipeptidyl peptidase-4; ER, endoplasmic reticulum; GIP, glucose-dependent insulinotropic polypeptide; GIPR, glucose-dependent insulinotropic polypeptide receptor; GLP-1, glucagon-like peptide-1; GLP-1R, glucagon-like peptide-1 receptor; HbA1c, hemo

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2007 سفارش ترجمه

Effect of fatty acid chain length on suppression of ghrelin and stimulation of PYY, GLP-2 and PP secretion in healthy men

Keywords: GLP-1، peptide-1 like glucagon; CCK, cholecystokinin; GLP-1, glucagon-like peptide-1; GLP-2, glucagon-like peptide-2; PP, pancreatic polypeptide; PYY, peptide YYFatty acid chain length; Ghrelin; Peptide YY; Glucagon-like peptide-2; Pancreatic polypeptide

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Insulin Dynamics Predict Body Mass Index and Z-Score Response to Insulin Suppression or Sensitization Pharmacotherapy in Obese Children

Keywords: GLP-1، peptide-1 like glucagon; BMI, Body mass index; CIRgp, Corrected Insulin Response; CISI, Composite Insulin Sensitivity Index; CNS, Central nervous system; GLP-1, Glucagon-like peptide-1; OGTT, Oral glucose tolerance testing; UCSF, University of California San Francisco; U.T., Univ

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Evaluation of the antidiabetic activity of DPP IV resistant N-terminally modified versus mid-chain acylated analogues of glucose-dependent insulinotropic polypeptide

Keywords: GLP-1، peptide-1 like glucagon; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide-1; DPP IV, dipeptidylpeptidase IV; (ob/ob) mice, obese diabetic mice; HPLC, high performance liquid chromatography; MALDI-TOF, matrix-assisted laser desorption ionization-time

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

The Effect of Production Level on Feed Intake, Milk Yield, and Endocrine Responses to Two Fatty Acid Supplements in Lactating Cows*

Keywords: GLP-1، peptide-1 like glucagon; fatty acid; saturation; milk protein; feed intakeCCK, cholecystokinin; FA, fatty acid; GLP-1, glucagon-like peptide-1; pFCMY, pre-trial fat-corrected milk yield; SAT, saturated fatty acids; ST, somatotropin; UNS, unsaturated fatty acids

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه