Keywords: CytcOx; cytochrome c oxidase; Dow; pH-dependent speciation of ionic compounds; GSTs; glutathione S-transferases; H+-ATPase; proton pump; Koc; organic carbon-normalized sorption coefficient; RWW; reclaimed wastewater; TPs; transformation products; Antibiot
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Keywords: Cancer; Resistance; Drug metabolizing enzymes; UGTs; GSTs; DPDs; TPMTs;
Keywords: HDACi; histone deacetylase inhibitor; HDAC; histone deacetylase; SCFA; short-chain fatty acids; GSTs; glutathione-S transferases; NRP-1; Neuropilin-1; P-gp; P-glycoprotein; CI; combination index; Butyrate; Colorectal cancer; Dietary fiber; Synergistic eff
Keywords: ATM; ataxia telangiectasia mutated; ATR; ATM-Rad3-related; AMPK; AMP-activated protein kinase; AD; Alzheimer's disease; ARE; antioxidant response element; ATF6; activating transcription factor 6; BiP; binding immunoglobulin protein; BRAC1; Breast cancer 1
Keywords: Bayesian analysis; Glutathione conjugation; Oxidative metabolism; Tetrachloroethylene; Physiologically based pharmacokinetic (PBPK) model; Risk assessment; CC; Collaborative Cross; CDC; Centers for Disease Control and Prevention; CU; coefficient of uncert
Keywords: Air pollution; allergic sensitization; asthma; Glutathione S-Transferase genes; respiratory function; aOR; Adjusted odds ratio; DEP; Diesel exhaust particle; GSTs; Glutahione S-Transferaese genes; GSTT1; Glutahione S-Transferaese theta1; GSTM1; Glutahione
Keywords: ADMET; absorption, distribution, metabolism, excretion, toxicity; AHR; aryl hydrocarbon receptor; AUC; area under the curve; BVU; (E)-5-(2-bromovinyl) uracil; CAR; constitutive androstane receptor; cMOAT; Canalicular multispecific organic anion transporte
Keywords: ARE; antioxidant response element; BBB; blood-brain barrier; CBF; cerebral blood flow; EBI; early brain injury; GSTs; glutathione S-transferases; HO-1; heme oxygenase-1; keap1; Kelch-like ECH-associated protein-1; MDA; malondialdehyde; MPO; myeloperoxid
Keywords: Anthocyanin; Chrysanthemum; Mutation; Radiation; Suppression subtractive hybridization; 3GT: UDP-glucose; anthocyanidin 3-O-glucosyltransferase; 5â²3GT; anthocyanidin 5â²3-O-glycosyltransferase; ANS; anthocyanidin synthase; CDD; conserved domain databas
Keywords: GSTs; glutathione-S transferases; LPS; lipopolysaccharide; NO; nitric oxide; NOS; nitric oxide synthase; NOS3; endothelial NOS; NOS1; neuronal NOS; NOS2; inducible NOS; NPC; nasopharyngeal carcinoma; OR; odds ratio; PCR; polymerase chain reaction; RFLP; r
Keywords: Benzene; Micronuclei; Polymorphism; CYP2E1; GSTs; mEH
Keywords: Diethylnitrosamine; Alkenal/one oxidoreductase; Carcinogen detoxification enzymes; 4-Hidroxynonenal; Tumor marker; HCC; hepatocellular carcinoma; DEN; diethylnitrosamine; S&F; Solt and Farber model; LTB4; leukotriene B4; PGE2; prostaglandin E2; 15d-PGJ2;
Keywords: Carotenes; Xanthophylls; NF-κB; Nrf2; Transcription factors; Chronic diseases; AMD; age-related macular degeneration; ARE; antioxidant response element; BCDO2; β-carotene dioxygenase 2; BCO1; β-carotene 15,15â²-oxygenase 1; CAT; catalase; CCL2; chemok
Keywords: AD; Alzheimer's disease; Aβ; β amyloid peptide; ERT; estrogen replacement therapy; ESR; estrogen receptor; E1; estrone; E2; estradiol; E3; estriol; CYP; cytochrome P450; CYP11A1; cytochrome P450 cholesterol side chain cleavage enzyme; HSD-3β; 3β-hydro
Association of the XRCC1 Arg194Trp and Arg399Gln polymorphisms with depression and hopelessness levels in individuals exposed to sour gas
Keywords: BDI; Beck depression inventory; BER; base excision repair; BHS; Beck hopelessness scale; GSTM1; glutathione S-transferse M1; GSTs; glutathione S-transferases; GSTT1; glutathione S-transferse T1; HWE; Hardy-Weinberg equilibrium; MIS; Masjid-i-Sulaiman; XRC
Characterization of catalytic and non-catalytic activities of EgGST2-3, a heterodimeric glutathione transferase from Echinococcus granulosus
Keywords: GSTs; glutathione transferases; CDNB; 1-choro-2,4-dinitrobenzene; GSH; glutathione; EgGST; E. granulosus glutathione transferase; rEgGST; recombinant EgGST; GPx; GSH peroxidase activity; DHA; dehydroascorbate; Echinococcus granulsosus; Glutathione transfe
Cap 'n' collar C regulates genes responsible for imidacloprid resistance in the Colorado potato beetle, Leptinotarsa decemlineata
Keywords: Insecticide resistance; RNA sequencing; RNA interference; Xenobiotic transcription factor; ABC transporter; P450; CPB; Colorado potato beetle; CncC; Cap 'n' collar isoform C; XTFs; Xenobiotic transcription factors; Nrf2; NF-E2-related factor 2; P450;
The multifaceted role of glutathione S-transferases in cancer
Keywords: Glutathione-S transferase; Carcinogenesis; Biomarkers; Drug resistance; Tumor suppressor; AD; Aricaidine; AP-1; Activator protein 1; ASK1; Apoptosis signal-regulating kinase; CSC; cancer stem cells; EGFR; Epidermal growth factor receptor; GSH; glutathione
Inhibition of NRF2 signaling and increased reactive oxygen species during embryogenesis in a rat model of retinoic acid-induced neural tube defects
Keywords: Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; ARE; antioxidant response element; HO-1; heme oxygenase-1; NQO1; NADP(H): quinine oxidoreductase 1; GSTs; glutathione S-transferases; TXNRD; thioredoxin reducta
Genotypes of GSTM1 and GSTT1: Useful determinants for clinical outcome of bladder cancer in Pakistani population
Keywords: GSTs; glutathione S transferases; GSTM1; glutathione S transferase mu 1; GSTT1; glutathione S transferase theta 1; BC; bladder cancer; LUTS; lower urinary tract symptoms; PCR; polymerase chain reaction; IRB & EC; Institutional Review Board and Ethics Comm
Effect of Glutathione S-transferase mu 1 (GSTM1) gene polymorphism on chronic myeloid leukemia risk and Imatinib treatment response
Keywords: ABL1; c-abl proto-oncogene 1 gene; BCR; breakpoint cluster region gene; CML; chronic myeloid leukemia; CP; chronic phase; CCgR; complete cytogenetic response; CHR; complete hematologic response; ELN; European LeukemiaNet; GSTs; Glutathione S-transferases
Protective effect of aqueous extract of Phyllanthus fraternus against bromobenzene induced changes on cytosolic glutathione S-transferase isozymes in rat liver
Keywords: AEPF; aqueous extract of Phyllanthus fraternus; BB; bromobenzene; CDNB; 1-chlro-2, 4-dinitrobenzene; CHAPS; (3-[(3-cholamidopropyl)-dimethylammino]-1-propane sulfonate); 2DE; two dimensional gel electrophoresis; DTT; dithiothretol; GSTs; glutathione S tra
Evaluating the potential cancer chemopreventive efficacy of two different solvent extracts of Seriphidium herba-alba in vitro
Keywords: Apoptosis; Chemoprevention; GSTs; Necrosis; PDGFBB; VEGF Seriphidium herba-alba;
Dietary lipids differentially modulate the initiation of experimental breast carcinogenesis through their influence on hepatic xenobiotic metabolism and DNA damage in the mammary gland
Keywords: AA; arachidonic acid; AhR; aryl-hydrocarbon receptor; c; control; CYP1; Cytochrome P450 family 1; DMBA; 7,12-dimethylbenz(a)anthracene; d.o.; days old; EROD; ethoxyresorufin-O-deethylase; GC/MS; gas chromatography/mass spectrometry; GSTs; glutathione S-tr
The potential implications of reclaimed wastewater reuse for irrigation on the agricultural environment: The knowns and unknowns of the fate of antibiotics and antibiotic resistant bacteria and resistance genes - A review
Keywords: Antibiotics; Accumulation; Human health risks; Antibiotic-resistance genes; Uptake; Reclaimed wastewater irrigation; APCI; atmospheric pressure chemical ionization; ARB; antibiotic resistant bacteria; ARGs; antibiotic resistance genes; CytcOx; cytochrome
Comparative proteomic analysis of cucumber roots infected by Fusarium oxysporum f. sp. cucumerium Owen
Keywords: Cucumis sativus; Fusarium wilt; 2-DE; Mass spectrum identification; Root proteomics; AOC; allene oxide cyclase; CFW; Cucumber Fusarium wilt; DHAR; DHAR class glutathione transferase; GSTs; glutathione stransferases; JA; jasmonic acid; MeJA; methyl jasmona
MicroRNAs as key mediators of hepatic detoxification
Keywords: CYP; cytochrome p450; UGTs; UDP glycosyltransferases; GSTs; glutathione-S-transferases; SULTs; sulfotransferases; OATs; organic anion transporters; MRPs; multidrug-resistance proteins; DGCR8; DiGeorge Syndrome Critical Region Gene 8; RISC; RNA-induced sil
Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1â²-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism
Keywords: CYP; cytochrome P450s; DEX; dexamethasone; E-3â²-N2-dGuo; N2-(trans-isoestragol-3â²-yl)-2â²-deoxyguanosine; GSTs; glutathione S transferases; OTM; olive tail moment; PAPSS; 3â²-phosphoadenosine 5â²-phosphosulphate synthase; PCP; pentachlorophenol; PN
Effects of chronic exposure to benzalkonium chloride in Oncorhynchus mykiss: cholinergic neurotoxicity, oxidative stress, peroxidative damage and genotoxicity
Keywords: Rainbow trout; Conservatives; Biomarkers; Comet assay; ENAs; GSTs; Catalase; AChE; TBARS;
The impact of detoxifying and repair gene polymorphisms and the levels of serum ROS in the susceptibility to multiple sclerosis
Keywords: Multiple sclerosis; GSTs; XRCC1; OGG1; Polymorphism; Reactive oxygen species
Species- and congener-differences in microcystin-LR and -RR GSH conjugation in human, rat, and mouse hepatic cytosol
Keywords: MC; microcystins; GSTs; glutathione transferases; HLC; human liver cytosol; RLC; rat liver cytosol; MLC; mouse liver cytosol; MD; male donor; FD; female donor; ED; mix gender donor; Microcystin-RR conjugation; MC-LR conjugation; Human hepatic cytosol; Rat
Genetic polymorphisms in GSTM1, GSTT1 and GSTP1 genes and risk of lung cancer in a North Indian population
Keywords: LC; lung cancer; SQCC; squamous cell carcinoma; ADCC; adenocarcinoma; SCLC; small cell lung carcinoma; GSTs; glutathione-S-transferases; OR; odds ratio; 95% CI; 95% confidence interval; PY; pack years; SD; standard deviation; ETS; environmental tobacco sm
Role of physiological mechanisms and EPSPS gene expression in glyphosate resistance in wild soybeans (Glycine soja)
Keywords: EPSPS; 5-enolpyruvylshikimate-3-phosphate synthase; GST; glutathione S-transferase; DAT; days after treatment; GR; glyphosate-resistant; GT; glyphosate treatment; R; resistant; S; susceptible; Glyphosate; Shikimic; Chlorophyll; GSTs; EPSPS mRNA levels;
Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway
Keywords: CD; Crohn's disease; COX2; cyclooxygenase 2; CYPs; cytochromes P450; DSS; dextran sodium sulfate; ELISA; enzyme linked immunosorbent assay; GSTs; glutathione S-transferases; IBD; inflammatory bowel disease; ICAM-1; Intercellular adhesion molecule-1; IL-2/
GSTM1, GSTT1, GSTP1, and GSTA1 genetic variants are not associated with coronary artery disease in Taiwan
Keywords: ANOVA; an analysis of variance; BMI; body mass index; CAD; coronary artery disease; CVD; cardiovascular disease; CIs; confidence intervals; DNA; deoxyribonucleic acid; DM; diabetes mellitus; dNTP; deoxyribonucleoside triphosphate; EDTA; ethylenediaminetet
New insights into the catalytic mechanism of Bombyx mori prostaglandin E synthase gained from structure-function analysis
Keywords: GSH; glutathione; GST; glutathione transferase; GSTS; Sigma-class GST; GTS; glutathione sulfonic acid; PG; prostaglandin; PGDS; prostaglandin D synthase; PGES; prostaglandin E synthase; SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis
Genetic variability of glutathione S-transferase enzymes in human populations: Functional inter-ethnic differences in detoxification systems
Keywords: GSTs; Glutathione S-Transferases; LoF; Loss-of-Function; MAPEG; Membrane-Associated Proteins involved in Eicosanoid and Glutathione metabolism; GSTA; GST alpha class; GSTM; GST mu class; GSTP; GST pi class; GSTT; GST theta class; GSTK; GST kappa class; GS
Association of glutathione S-transferase polymorphisms (GSTM1 and GSTT1) with primary open-angle glaucoma: An evidence-based meta-analysis
Keywords: GSTs; glutathione S-transferases; GSTM1; glutathione S-transferase mu 1; GSTT1; glutathione S-transferase theta 1; POAG; primary open-angle glaucoma; IOP; intraocular pressure; ROS; reactive oxygen species; OR; odds ratio; CI; confidence interval; HWE; Ha
The conjugation of microcystin-RR by human recombinant GSTs and hepatic cytosol
Keywords: MC; microcystins; GSTs; glutathione transferases; HLC; human liver cytosol; CDNB; 1-chloro-2,4-dinitrobenzene; MD; male donor; FD; female donor; ED; mix gender donor; Microcystin-RR detoxication; Human GSTs; Conjugation reaction; Human hepatic cytosol;
Reduction of antibiotics using microorganisms containing glutathione S-transferases under immobilized conditions
Keywords: Antibiotics; Immobilization; GSTs; Degradation; Microorganisms
Identification of novel glutathione transferases in Echinococcus granulosus. An evolutionary perspective
Keywords: GSTs; glutathione transferases; GSTY; tyrosine-type of GSTs; SDS-PAGE; sodiumdodecylsulfate-polyacrylamidegelelectrophoresis; PDB-ID; Protein Data Bank identification; dN; non-synonymous substitutions; dS; synonymous substitutions; Glutathione transferase
The identification and oxidative stress response of a zeta class glutathione S-transferase (GSTZ1) gene from Apis cerana cerana
Keywords: ROS; reactive oxygen species; GSTs; glutathione S-transferases; cDNA; complementary DNA; bp; base pair(s); UTR; untranslated region; ORF; open reading frame; mRNA; messenger ribonucleic acid; RACE; rapid amplification of cDNA ends; RT-PCR; reverse transcr
The protective effect of magnesium lithospermate B against glucose-induced intracellular oxidative damage
Keywords: LAB; magnesium lithospermate B; ROS; reactive oxygen species; HO-1; heme oxygenase-1; Nrf2; nuclear factor E2-related factor2; GSTs; glutathione S-transferases; CAT; hydrogen peroxidase; H2O2; hydrogen peroxide; SOD; superoxide dismutase; O2â; superoxid
Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA industry sectors
Keywords: ADME; absorption, distribution, metabolism, and excretion; ADI; Acceptable Daily Intake; Colipa; the European Cosmetic Toiletry and Perfumery Association; CYPs; cytochrome P450s; DNEL; Derived No Effect Level; DG; Directorate General; ECHA; EU Chemicals A
Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers
Keywords: 1,3-butadiene; Chromosomal damage; MN; GSTs; CYP2E1; mEH
Effects of genetic polymorphisms CYP1A1, GSTM1, GSTT1 and GSTP1 on urinary 1-hydroxypyrene levels in sugarcane workers
Keywords: Sugarcane workers; 1-Hydroxypyrene (1-OHP); Genetic polymorphisms; Polycyclic aromatic hydrocarbons (PAHs); CYPs; GSTs
Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species
Keywords: ARE; Antioxidant-responsive element; BHA; Butylated hydroxyanisole; BTB; Broad complex-tramtrack-bric-a-brac; bZip; Basic leucine zipper; CBP; CREB binding protein; C/EBPβ; CCAAT/enhancer binding protein β; CNC; Cap' n' collar; Cox2; Cyclooxygenase
Microarray analysis on Phase II drug metabolizing enzymes expression in pregnant rats after treatment with pregnenolone-16α-carbonitrile or phenobarbital
Keywords: GSTs; Microarray analysis; Pregnenolone-16α-carbonitrile (PCN); Phenobarbital; Pregnant rat; UDPGTs;
Synthesis and analysis of chimeric maize glutathione transferases
Keywords: Dimerisation; GSTs; Herbicide detoxification; Protein engineering; Domain swapping; Phi class GST; Tau class GST; Zea mays;