Keywords: ABA; abscisic acid; ABI; ABA-insensitive; AIM/LIR; ATG8-interacting motif/LC3-interacting region; AREB/ABFs; ABRE-binding protein/ABRE-binding factor; ARM; armadillo repeat; Atg8; autophagy-related 8; BAG6; BCL-2 associated athanogene 6; BiPs; lumenal bin
مقالات ISI (ترجمه نشده)
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Keywords: Ub; ubiquitin; UBLs; ubiquitin-like proteins; DUBs; deubiquitinating enzymes; TCR; T cell receptor; UPS; ubiquitin-proteasome system; IAPs; inhibitors of apoptosis-related proteins; GAPs; GTPase-activating proteins; PI3K; phosphatidylinositol 3-kinase;
Keywords: AL; Air Laboratory; AMCV; Air Monitoring Comparison Value; APWL; Air Pollutant Watch List; AutoGC; Automated Gas Chromatography; CFR; Code of Federal Regulation; EI; Emissions Inventory; EPA; Environmental Protection Agency; HECT; HRVOC Emission Cap and T
Keywords: Ub; ubiquitin; SCF; Skp-Cullin-F-box; HECT; homologous to E6 carboxyl terminus; RING; really Interesting New Gene; SUMO; small ubiquitin-like modifier; UPS; ubiquitin proteasome system; UFD; ubiquitin fusion degradation; ERAD; endoplasmic reticulum-associ
Seeing is understanding: Salmonella's way to penetrate the intestinal epithelium
Keywords: ARNO; adenosine diphosphate (ADP) ribosylation factor nucleotide exchange factor; BMP; bone morphogenetic protein; Cdc42; cell division control protein 42 homolog; CFU; colony forming unit; EGF; epithelial growth factor; Ets; E26 transformation-specific;
Ubiquitin-proteasome signaling in lung injury
Keywords: AJ; adherens junctions; ALI; acute lung injury; AMPK; adnosine monophosphate activated protein kinase; ARDS; acute respiratory distress syndrome; ATP; adenosine triphosphate; CFTR; cystic fibrosis transmembrane conductance regulator; cIAP; cellular inhibi
A partnership with the proteasome; the destructive nature of GSK3
Keywords: AMPK; AMP-activated protein kinase; ARE; antioxidant response element; β-TrCP; beta-transducin repeat containing protein; CKI; casein kinase-1; CHD; chromatin helicase DNA-binding factor; CRY; cryptochrome; EMT; epithelial-mesenchymal transition; FGD; fa
Generation of SMURF2 knockout human cells using the CRISPR/Cas9 system
Keywords: SMURF2; CRISPR/Cas9; Knockout; Human cells; SMURF2; Smad Ubiquitination Regulatory Factor 2; HECT; homologous to E6-AP COOH-terminus; CRISPR; clustered regularly interspaced short palindromic repeats; Cas9; CRISPR-associated protein 9; ZFNs; zinc finger n
Expression in Escherichia coli, purification and characterization of LRSAM1, a LRR and RING domain E3 ubiquitin ligase
Keywords: LRSAM1; Ubiquitin ligase; RING-finger; Purification; Activity; LRSAM1; Human leucine rich repeat and sterile alpha motif containing 1; RING; really interesting new gene; HECT; the homology to E6AP carboxyl terminus; LRR; leucine-rich repeats; E. coli; Esc
E6AP/UBE3A catalyzes encephalomyocarditis virus 3C protease polyubiquitylation and promotes its concentration reduction in virus-infected cells
Keywords: 3C protease; ARIH1; E6AP/UBE3A; Encephalomyocarditis virus; UbcH7/UBE2L3; Ubiquitylation; 3Cpro; 3C protease; EMCV; encephalomyocarditis virus; HRV; human rhinovirus; HECT; homologous to E6AP carboxyl terminus; RBR; ring between ring; RING; really interes
Reviewp53 stability is regulated by diverse deubiquitinating enzymes
Keywords: UPP; Ubiquitin-proteasome pathway; DUB; Deubiquitinating enzyme; PTM; Post-translational modification; E1; Ubiquitin-activating enzyme; E2; Ubiquitin-conjugatng enzyme; E3; Ubiquitin ligase; RING; Really interesting new gene; HECT; Homologous to E6-AP car
CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response
Keywords: CXCR4; CXCR7; Cardiogenesis; hiPSC; Engineered tissue; hiPSC; human induced pluripotent stem cell; hiPSC-CM; human induced pluripotent stem cell-derived cardiomyocyte; hECT; human engineered cardiac tissue; GPCR; G-protein coupled receptor; SDF-1; stromal
Immune defects caused by mutations in the ubiquitin system
Keywords: Ubiquitin; nuclear factor κB; immunodeficiency; CVID; Common variable immunodeficiency; DUB; Deubiquitinating enzyme; EDA-ID; Ectodermal dysplasia with immunodeficiency; HECT; Homologous to EGAP C-terminus; HOIL-1; Heme-oxidase iron responsive element bi
Modulation of hippocampal synapse maturation by activity-regulated E3 ligase via non-canonical pathway
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BCA; bicinchoninic acid; CA; Cornu Ammonis; DG; Dentate Gyrus; DIV; days in vitro; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GFAP; Glial Fibrilary Acidic Protein; GFP; Green Fluorescent P
The E3 ubiquitin ligase MID1/TRIM18 promotes atypical ubiquitination of the BRCA2-associated factor 35, BRAF35
Keywords: BHC; BRAF-histone deacetylase; BRAF35/HMG20b; BRCA2-associated factor 35; CC; coiled-coil; coREST/RCOR1; REST corepressor 1; E1; UBE1, ubiquitin activating enzyme; E2; UBE2 ubiquitin conjugating enzyme; E3; ubiquitin ligase enzyme; FN3; fibronectin type I
Cullin 5-RING E3 ubiquitin ligases, new therapeutic targets?
Keywords: E3 ubiquitin ligase; Cullin RING ligase; Ubiquitin-proteasome system; Therapeutic targets; ASB; ankyrin repeat-containing proteins with a SOCS box; β-Trcp; β-transducin repeat-containing protein; BTB; bric-a-brac; CIS1; cytokine-inducible Src homology
Regulation of connexins by the ubiquitin system: Implications for intercellular communication and cancer
Keywords: AMSH; associated molecule with the SH3 domain of STAM (signal transducing adaptor molecule); ATP; adenosine triphosphate; cAMP; cyclic adenosine monophosphate; CIP75; Cx43-interacting protein of 75 kD; CIP85; Cx43-interacting protein of 85 kDa; Cx; connex
Regulation of peroxisomal matrix protein import by ubiquitination
Keywords: AAA; ATPase associated with diverse cellular activities; APEM9; aberrant peroxisome morphology 9; HECT; homologous to the E6-AP carboxyl-terminus; PTS; peroxisomal targeting sequence; RBR ligase; RING-between-RING ligase; RING; really interesting new gene
Regulation of the TGF-β pathway by deubiquitinases in cancer
Keywords: AMSH; Associated molecule with SH3 domain proteases; AMSH-LP; Associated molecule with SH3 domain-like proteases; ATXN3; ataxin-3; ATXN3L; ataxin 3-like; BMPs; bone morphogenetic proteins; BRCC36; BRCA1/BRCA2-containing complex subunit 36; CHIP; carboxy t
Synaptic structure and function are altered by the neddylation inhibitor MLN4924
Keywords: NEDD8; neural precursor cell expressed, developmentally down-regulated 8; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; Ubc12; ubiquitin carrier protein 12; RING; really interesting new gene; HECT; homologous to the E6-AP carboxyl
Mechanisms of p53 degradation
Keywords: ATM; ataxia telangiectasia mutated; CHIP; C-terminus of HSP70-interacting protein; CBP; CREB binding protein; COP1; constitutively photo-morphogenic 1; DDB1; DNA damage binding protein 1; DHFR; dihydrofolate reductase; DUB; de-ubiquitinating enzyme; E1; u
NEDD4: The founding member of a family of ubiquitin-protein ligases
Keywords: RING; Really Interesting New Gene; HECT; Homologous to E6-AP C-Terminus; Ndfip1; Nedd4 family interacting protein 1; AMPARs; alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid receptors; EGFR; epidermal growth factor receptor; FGFR1; Fibroblast gro
Identification of HECT E3 ubiquitin ligase family genes involved in stem cell regulation and regeneration in planarians
Keywords: HECT; Planarian; Stem cells; HUWE1; TRIP12; WWP1;
Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing
Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-
Human CTP:phosphoethanolamine cytidylyltransferase: Enzymatic properties and unequal catalytic roles of CTP-binding motifs in two cytidylyltransferase domains
Keywords: CCT; CTP:phosphocholine cytidylyltransferase; CDP-Etn; CDP-ethanolamine; CT; cytidylyltransferase; DTT; dithiothreitol; ECT; CTP:phosphoethanolamine cytidylyltransferase; GCT; CTP:glycerol-3-phosphate cytidylyltransferase; hECT; human ECT; PE; phosphatidy
Classification and interaction modes of 40 rice E2 ubiquitin-conjugating enzymes with 17 rice ARM-U-box E3 ubiquitin ligases
Keywords: HECT; homology to E6-AP carboxyl-terminus; MBP; maltose binding protein; PCR; polymerase chain reaction; RING; really interesting new gene; E2 ubiquitin-conjugating enzyme; ARM-U-box E3 ubiquitin-ligase; E2-E3 interaction; Rice (Oryza sativa L.); Ubiqui
The VTLISFG motif in the BH1 domain plays a significant role in regulating the degradation of Mcl-1
Keywords: Apoptosis; Mcl-1; Degradation motif; PEST domain; β-TrCP; β-transducin repeat-containing protein; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma-2; BH domain; Bcl-2 homology domain; Bim; Bcl-2-interacting mediator; BSA; bovine serum albumin; Ca
Ubiquitin in the peroxisomal protein import pathway
Keywords: Ubiquitination; Peroxisome; PEX5; Thioester; Protein trafficking; AAA; ATPases associated with diverse cellular activities; DTM; docking/translocation module; DUBs; deubiquitinating enzymes; E1; ubiquitin-activating enzyme; E2; ubiquitin-conjugating enzym
Hectd1 is required for development of the junctional zone of the placenta
Keywords: HECT; homologous to E6-AP carboxyl terminus; Ub; ubiquitin; IUGR; intrauterine growth restriction; TGC; trophoblast giant cell; H&E; hematoxylin and eosin; PAS; periodic acid-Schiff; uNK; uterine natural killer cells; HECT E3 ligase; Placenta; Trophoblast
Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity
Keywords: AIP4; atrophin-interacting protein 4; Baf; bafilomycin; BMP; bis(monoacylglycero)phosphate; CMA; chaperone-mediated autophagy; CQ; chloroquine; HD; Huntington disease; HECT; homologous to E6-AP C-terminus; IB; inclusion bodies; Lamp2a; lysosome associated
Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis
Keywords: APC/C; Anaphase Promoting Complex/Cyclosome; AOM; azoxymethane; Bub3; budding uninhibited by benzimidazole protein 3; BubR1; bub1-related protein; Cdc20; cell division cycle 20; Cdh1; Cdc20 homologue protein 1; DMBA; 7,12-dimethylbenz-α-anthracene; Emi1;
Role of the ubiquitin-proteasome system in brain ischemia: Friend or foe?
Keywords: 3-MA; 3-methyladenine; 15d-PHJ2; 15-deoxy-Î12,14-prostaglandin J2; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole proprionic acid; AMPAR; AMPA receptors; APC/C; anaphase-promoting complex/cyclosome; APV; D-aminophosphonovalerate; ATF4; activating transcri
Identification of ubiquitin-modified lysine residues and novel phosphorylation sites on eukaryotic initiation factor 2B epsilon
Keywords: DMEM; Dulbecco's modified Eagle's medium; eIF; eukaryotic initiation factor; HECT; homologous to E5-AP carboxyl terminus; LC; liquid chromatography; MS/MS; tandem mass spectrometry; NEDD4; neural precursor cell expressed, developmentally down-regulate
Suppression of Arabidopsis RING E3 ubiquitin ligase AtATL78 increases tolerance to cold stress and decreases tolerance to drought stress
Keywords: ABA; abscisic acid; ATL; Arabidopsis Tóxicos en Levadura; AtAIRP; Arabidopsis thaliana ABA-insensitive RING protein; AtRDUF; Arabidopsis thaliana RING domain-of-unknown-function; CRWL; cut rosette water loss; DAB; 3,3â²-diaminobenzidine; HECT; the homol
NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway
Keywords: AKT; v-akt murine thymoma viral oncogene; CRC; colorectal cancer; FDR; false discovery rate; HECT; homologous to E6AP C terminus; KEGG; Kyoto Encyclopedia of Genes and Genomes; mut; mutated; NCBI; National Center for Biotechnology Information; PBS; phosph
The HECTD3 E3 Ubiquitin Ligase Suppresses Cisplatin-Induced Apoptosis via Stabilizing MALT1
Keywords: CHX; cycloheximide; DD; death domain; DOC; destruction of cyclin; HECT; homologous to the E6-associated protein carboxyl terminus; HECTD3; HECT domain containing 3; IP; immunoprecipitation; MALT; mucosa-associated lymphoid tissue; SPR; surface plasmon res
Neurobehavioral effects of exposure to traffic-related air pollution and transportation noise in primary schoolchildren
Keywords: CI; Confidence Interval; dB(A); A-weighted frequency spectrum in decibel; Df; Degrees of freedom; DMST; Digit Memory Span Test; HECT; Hand-Eye Coordination Test; LAeq,7-23Â h; A-weighted equivalent sound pressure level for the period from 7:00 to 23:0
Endocytosis and post-endocytic sorting of connexins
Keywords: CHO; Chinese hamster ovary; CIP75; connexin43-interacting protein of 75-kDa; CIP85; connexin43-interacting protein of 85-kDa; Dab2; disabled-2; EEA1; early endosomal autoantigen 1; EGF; epidermal growth factor; ENaC; amiloride-sensitive epithelial sodium
Ubiquitination of LHY by SINAT5 regulates flowering time and is inhibited by DET1
Keywords: E1; ubiquitin-activating enzyme; E2; ubiquitin-conjugating enzyme; E3; ubiquitin ligase; HECT; E6-associated protein carboxyl terminus; SINA; seven in absentia; SINAT5; an Arabidopsis homologue of the SINA; Siah1; a human homologue of the SINA; NAC1; NOAP
The E3 ubiquitin ligase WWP1 regulates ÎNp63-dependent transcription through Lys63 linkages
Keywords: Ubiquitin; HECT; Ubiquitin ligase; p63; Transcription; Cell death; Skin; Epidermis;
Caspase cleavage of Itch in chronic lymphocytic leukemia cells
Keywords: Hect; Ubiquitin; E3; Caspases; Apoptosis; p53; Chemotherapy; TRAIL; HDACi; CLL
Itch regulates p45/NF-E2 in vivo by Lys63-linked ubiquitination
Keywords: Itch; NF-E2; p45; Lys63-linkage; Ubiquitin; HECT; E3 ligase; Hematopoiesis; Megakaryocytic; Erythroid
The neuronal ubiquitin-proteasome system: Murine models and their neurological phenotype
Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; AR-JP; Autosomal Recessive-Juvenile Parkinsonism; AS; Angelman syndrome; CHIP; C-terminal Hsp70 interacting protein; DA; dopamine; DUB; deubiquitinating enzyme; ERAD; endoplasmatic reticulum (ER-) associated degra
Sequence Determinants of E2-E6AP Binding Affinity and Specificity
Keywords: β-Me, β-mercaptoethanolubiquitin; UbcH7; E6AP; HECT; E2–E3 specificity
G2E3 is a nucleo-cytoplasmic shuttling protein with DNA damage responsive localization
Keywords: Nucleolus; DNA damage; Ubiquitin ligase; HECT; CRM1; Leptomycin B; Nuclear export
Targeted protein degradation
Keywords: HECT; homology to E6AP C-terminus; HPV; human papillomavirus; Protac; proteolysis targeting chimeric molecule; Rb; retinoblastoma; RING; Really Interesting New Gene; SCF; Skp1, Cullin 1, F-box-containing substrate receptor, and the Rbx1/Roc1/Hrt1 ubiquiti
The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects
Keywords: Ubiquitin ligase; HERC; HECT; RCC1; Alternative splicing; Evolution;