دانلود مقالات ISI درباره HMG-CoA ردوکتاز + ترجمه فارسی

Proteolytic hydrolysis of cowpea proteins is able to release peptides with hypocholesterolemic activity

Keywords: HMG-CoA ردوکتاز; Taurocholate (PubChem CID 23666345); Cholestrol (PubChem CID 5997); Phosphatidylcholine (PubChem CID 45266626); NADPH (PubChem CID 5884); Pravastatin (PubChem CID 54687); HMG-CoA (PubChem CID 445127)Cowpea bean; HMG-CoA reductase; Micellar cholesterol sol

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Peptide inhibitors of human HMG-CoA reductase as potential hypocholesterolemia agents

Keywords: HMG-CoA ردوکتاز; ELISA; enzyme-linked immunosorbent assay; HMG-CoA; 3-hydroxyl-3-methylglutaryl coenzyme A; hHMGR; human HMG-CoA reductase; HRP; horseradish peroxidase; IPTG; isopropyl β-d-1-thiogalactopyranoside; LB buffer; Luria-Bertani buffer; LDL; low density lipopro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Phenolics from grapefruit peels inhibit HMG-CoA reductase and angiotensin-I converting enzyme and show antioxidative properties in endothelial EA.Hy 926 cells

Keywords: HMG-CoA ردوکتاز; Endothelial cells; Antioxidant; Angiotensin-I converting enzyme; Grapefruit peels; HMG-CoA reductase

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Physiological feedback regulation of cholesterol biosynthesis: Role of translational control of hepatic HMG-CoA reductase and possible involvement of oxylanosterols

Keywords: HMG-CoA ردوکتاز; HMG-CoA reductase; 3-hydroxy-3-methylgutaryl coenzyme A reductase; LDL; low density lipoprotein; HDL; high density lipoprotein; SRE; sterol response element; SREBP-2; sterol response element binding protein-2; Scap; SREBP cleavage-activating protein; Insi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Effect of Eclipta prostrata on lipid metabolism in hyperlipidemic animals

Keywords: HMG-CoA ردوکتاز; Eclipta prostrata; Antioxidant; Hyperlipidemia; Triton WR-1339; HMG-CoA reductase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of HMG-CoA reductase by MFS, a purified extract from the fermentation of marine fungus FusaFusarium solani FG319, and optimization of MFS production using response surface methodology

Keywords: HMG-CoA ردوکتاز; Metabolite; HPLC analysis; HMG-CoA reductase; Response surface methodology

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Differentiation and apoptosis induction by lovastatin and γ-tocotrienol in HL-60 cells via Ras/ERK/NF-κB and Ras/Akt/NF-κB signaling dependent down-regulation of glyoxalase 1 and HMG-CoA reductase

Keywords: HMG-CoA ردوکتاز; GLO1, glyoxalase 1; HMGCR, HMG-CoA reductase; ERK, extracellular signal regulated kinases; Akt, protein kinase B; NF-κB, nuclear factor kappa-B; MG, methylglyoxalGlyoxalase 1; HMG-CoA reductase; Lovastatin; Apoptosis; Leukemia; γ-Tocotrienol; Differentiat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Cholesterol-lowering effects and potential mechanisms of different polar extracts from Cyclocarya paliurus leave in hyperlipidemic mice

Keywords: HMG-CoA ردوکتاز; Arjunolic acid (PubChem CID: 73641); Cyclocaric acid B (CAS no.182315-46-4); Pterocaryoside B (CAS no. 168146-27-8); Hederagenin (PubChem CID: 258538); 3β, 23-dihydroxy-12-ene-28-ursolic acid (CAS no. 125137-37-3); Oleanolic acid (PubChem CID: 10494).; C

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Structural bisphenol analogues differentially target steroidogenesis in murine MA-10 Leydig cells as well as the glucocorticoid receptor

Keywords: HMG-CoA ردوکتاز; 5αRed1; 5α-reductase type 1; 3β-HSD(1); 3β-hydroxysteroid dehydrogenase (type 1); 17β-HSD(3); 17β- hydroxysteroid dehydrogenase (type 3); cAMP; 8-bromoadenosine 3′,5′-cyclic monophosphate; AR; androgen receptor; BPA; bisphenol A; BPF; bisphenol

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

MYC and metabolism on the path to cancer

Keywords: HMG-CoA ردوکتاز; 2-DG; 2-deoxyglucose; 4E-BP; eIF4E-binding protein; 5,10-methylene THF; 5,10-methylenetetrahydrofolate; ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ChIP-seq; chromatin immunoprecip

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

Understanding the molecular mechanism of host-based statin resistance in hepatitis C virus replicon containing cells

Keywords: HMG-CoA ردوکتاز; Statins; Hepatitis C virus; Resistance; HMG-CoA reductase; Efflux;

دانلود رایگان متن کامل مقاله ISI 74 صفحه سال انتشار : 2015 سفارش ترجمه

Synthetic studies on statins. Part 3: A facile synthesis of rosuvastatin calcium through catalytic enantioselective allylation strategy

Keywords: HMG-CoA ردوکتاز; Rosuvastatin calcium; HMG-CoA reductase; Keck asymmetric allylation; VO(acac)2; syn-Epoxidation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Potential synergistic effects of Chinese herbal prescription FTZ components detected in blood towards hepatic lipid-modulating targets

Keywords: HMG-CoA ردوکتاز; TCM; traditional Chinese medicine; UPLC/Q-TOF-MS; ultra-performance liquid chromatography/quadruple-time-of-flight mass-spectrometry; RC; Rhizoma Coptidis; RSM; Radix Salvia Miltiorrhiza; TC; total cholesterol; TG; total triglyceride; LDL-C; low density l

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Kinetic characterization of an oxidative, cooperative HMG-CoA reductase from Burkholderia cenocepacia

Keywords: HMG-CoA ردوکتاز; Burkholderia cenocepacia; HMG-CoA reductase; Enzyme cooperativity; Isoprenoid biosynthesis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors

Keywords: HMG-CoA ردوکتاز; Hypolipidemic; Docking; 2-Acyl phenols; 2-Alkyl phenols; Phenoxyacetic; HMG-CoA reductase;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Computational simulation of the effect of quantum chemical parameters on the molecular docking of HMG-CoA reductase drugs

Keywords: HMG-CoA ردوکتاز; DFT calculations; Molecular docking; HMG-CoA reductase; Inhibition efficiency; Molecular electrostatic potential;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Overexpression of a key regulator of lipid homeostasis, Scap, promotes respiration in prostate cancer cells

Keywords: HMG-CoA ردوکتاز; CHO; Chinese hamster ovary; ER; endoplasmic reticulum; FASN; fatty acid synthase; FCS; foetal calf serum; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HMGCR; HMG-CoA reductase; LDH; lactate dehydrogenase; LDLR; low-density lipoprotein receptor; MT-ND1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Bioefficacy of EPA-DHA from lipids recovered from fish processing wastes through biotechnological approaches

Keywords: HMG-CoA ردوکتاز; Fish visceral waste; Fermentation; Enzymatic hydrolysis; EPA; DHA; HMG-CoA reductase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Resveratrol protects against atherosclerosis, but does not add to the antiatherogenic effect of atorvastatin, in APOE*3-Leiden.CETP mice

Keywords: HMG-CoA ردوکتاز; CETP; cholesteryl ester transfer protein cox1/-2, cyclooxygenase-1/-2; CXCL1; chemokine (C-X-C motif) ligand-1; E3L; APOE*3-Leiden transgenic; HMG-CoA reductase; 3-hydroxy-3-methylglutaryl coenzyme A reductase; Ig; immunoglobulin; IL; interleukin; 8-iso-P

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase

Keywords: HMG-CoA ردوکتاز; TERT; telomerase reverse transcriptase; mTOR; mechanistic target of rapamycin; S6K; p70 S6 kinase; 4E-BP1; 4E-binding protein 1; eIF4; eukaryotic initiation factor 4; PI3K; phosphoinositide 3-kinase; CHAPS; 3-[(3-Cholamidopropyl)dimethylammonio]-l-propane

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells

Keywords: HMG-CoA ردوکتاز; LDL receptor; HMG-CoA reductase; Cholesterol transporters; Lipid homeostasis; Chylomicron; Apo B-48; ABC; ATP binding cassette transporter; ACAT; acylcoenzyme A: cholesterol acyltransferase; Ab; antibody; Apo; apolipoprotein; CD36; cluster determinant 36/

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases

Keywords: HMG-CoA ردوکتاز; LXR; Oxysterols; Dementia; Biomarker; Mass spectrometry; 24OHC; 24S-hydroxycholesterol; 27OHC; 27-hydroxycholesterol; Aβ; amyloid beta; ABC; ATP-binding cassette transporter; ACAT; acyl-Coa:cholesterol acyltransferase; AD; Alzheimer disease; Apoe; apolip

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Evaluation of cholesterol absorption and biosynthesis by decoctions of Annona cherimola leaves

Keywords: HMG-CoA ردوکتاز; Annona cherimola; Rutin; Hypercholesterolemia; Cholesterol uptake; HMG-CoA reductase; Caco-2 cells

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Stem-bark of Terminalia arjuna attenuates human monocytic (THP-1) and aortic endothelial cell activation

Keywords: HMG-CoA ردوکتاز; AE; alcohol extract; Butylated hydroxytoluene; (BHT); H2DCFDA; 2´,7´-dichlorofluorescin diacetate; HAECs; Human aortic endothelial cells; 3-hydroxy-3-methylglutaryl coenzyme A; HMG-CoA reductase; ICAM-1; Intercellular adhesion molecule-1; IL-8; Interleu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Atorvastatin inhibits RhoC function and limits head and neck cancer metastasis

Keywords: HMG-CoA ردوکتاز; Head and neck squamous cell carcinoma; RhoC; HMG-COA reductase; Geranylation; Lung metastasis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Activation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase during high fat diet feeding

Keywords: HMG-CoA ردوکتاز; HMG-CoA reductase; Cholesterol; SREBP-2; Fatty liver

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Post-translational events and modifications regulating plant enzymes involved in isoprenoid precursor biosynthesis

Keywords: HMG-CoA ردوکتاز; DMAPP; dimethylallyl diphosphate; FPP; farnesyl diphosphate; GGPP; geranylgeranyl diphosphate; GPP; geranyl diphosphate; HMG-CoA; 3-hydroxy-3-methylglutaryl-coenzyme A; LC; liquid chromatography; ROS; reactive oxygen species; Isoprenoid biosynthesis; Meth

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

The increase in cholesterol levels at early stages after dengue virus infection correlates with an augment in LDL particle uptake and HMG-CoA reductase activity

Keywords: HMG-CoA ردوکتاز; Cholesterol; LDL receptor; HMG-CoA reductase; Dengue virus; Lipid rafts

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

The impact of severe LDL receptor mutations on SREBP-pathway regulation in homozygous familial hypercholesterolemia (FH)

Keywords: HMG-CoA ردوکتاز; ABCA1; ATP binding cassette transporter A1; FH; familial hypercholesterolemia; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HDL; high density lipoprotein; HMGCR; HMG-CoA reductase; INSIG-1; insulin induced gene 1; LDL; low density lipoprotein; LDLR; l

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of fibre-enriched diets on tissue lipid profiles of MSG obese rats

Keywords: HMG-CoA ردوکتاز; MSG; Fibre; Obesity; Dyslipidemia; HMG-CoA reductase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of RYR, MFA and MFB on serum lipids and antioxidant activity in rats

Keywords: HMG-CoA ردوکتاز; Red yeast rice; Monascus metabolites; HMG-CoA reductase; ACAT; Fecal sterols; Antioxidant enzymesHDL, high density lipoprotein; HMG-CoA, 3-hydroxy-3-methylglutaryl-CoA; ACAT, acyl CoA:cholesterol acyltransferase; RYR, red yeast rice; MFA, monasfluore A; M

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Alcohol depletes coenzyme-Q10 associated with increased TNF-alpha secretion to induce cytotoxicity in HepG2 cells

Keywords: HMG-CoA ردوکتاز; HepG2 cells; Ethanol; Triacylglycerol; Phospholipids; HMG-CoA reductase; Coenzyme-Q10; TNF-alpha;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Microbial transformation of lovastatin by Beauveria bassiana

Keywords: HMG-CoA ردوکتاز; Lovastatin; Microbial transformation; Beauveria bassiana AS 3.4270; Resting cells; HMG-CoA reductase

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Influence of large molecular polymeric pigments isolated from fermented Zijuan tea on the activity of key enzymes involved in lipid metabolism in rat

Keywords: HMG-CoA ردوکتاز; LMPP; large molecular polymeric pigments; FC; free cholesterol; TC; total cholesterol; TG; triacylglycerol; HDL-C; high density lipoprotein-cholesterol; LDL-C; low density lipoprotein-cholesterol; HL; hepatic lipase; HSL; hormone-sensitive lipase; LCAT; l

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

DPA n-3, DPA n-6 and DHA improve lipoprotein profiles and aortic function in hamsters fed a high cholesterol diet

Keywords: HMG-CoA ردوکتاز; Docosahexaenoic acid; Docosapentaenoic acid; Total cholesterol; HMG-CoA reductase; SREBP-2; Vascular reactivity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Prooxidative toxicity and selenoprotein suppression by cerivastatin in muscle cells

Keywords: HMG-CoA ردوکتاز; HMG-CoA reductase; Mevalonate pathway; Myopathy; Oxidative stress; Selenoproteins; Statins

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells

Keywords: HMG-CoA ردوکتاز; Cholesterol; HMG-CoA reductase; mevalonic acid; farnesyl pyrophosphate; geranylgeranyl pyrophosphate; ovarian theca-interstitial cells; resveratrol; simvastatin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Role and classification of cholesterol-lowering functional foods

Keywords: HMG-CoA ردوکتاز; ACAT; CETP; Cholesterol; HDL; HMG-CoA reductase; LDL; Lipoproteins; Nutraceuticals; NPC1L1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

A new TCM formula FTZ lowers serum cholesterol by regulating HMG-CoA reductase and CYP7A1 in hyperlipidemic rats

Keywords: HMG-CoA ردوکتاز; FTZ; Fufang Zhenzhu Tiao Zhi; HMG-CoA reductase; 3-hydroxy-3-methylglutaryl coenzyme A reductase; CYP7A1; cholesterol 7α-hydroxylase; Ch; cholesterol; BA; bile acid; TCM; Traditional Chinese Medicine; HPLC; high performance liquid chromatograph; Hyperlip

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases

Keywords: HMG-CoA ردوکتاز; Mevalonate pathway; Metabolic pathway optimization; HMG-CoA Reductase; E. coli; Cofactor regeneration; Mevalonate kinase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway

Keywords: HMG-CoA ردوکتاز; Anaplastic thyroid cancer; HMG-CoA reductase; Lovastatin; p27; Rho

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Hepatic Overexpression of Abcb11 Promotes Hypercholesterolemia and Obesity in Mice

Keywords: HMG-CoA ردوکتاز; Mouse Model; Micelle; Energy Expenditure; Bile Salt Export Pump; CYP7A1; cholesterol 7α-hydroxlyase; FGF; fibroblast growth factor; HMG-CoAR; HMG-CoA reductase; NPC1L1; Niemann-Pick C1 like 1; TTR; transthyretin; WT; wild-type;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Insulin-induced gene: A new regulator in lipid metabolism

Keywords: HMG-CoA ردوکتاز; Insigs; SCAP; HMG-CoA reductase; Cholesterol metabolism; Lipogenesis; Glucose homeostasis; Disease

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Hypocholesterolemic activity of grape seed proanthocyanidin is mediated by enhancement of bile acid excretion and up-regulation of CYP7A1

Keywords: HMG-CoA ردوکتاز; Cholesterol; Grape seed proanthocyanidin; CYP7A1; LDL receptor; HMG-CoA reductase; SREBP-2; Liver X receptor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Farnesyltransferase inhibitor improved survival following endotoxin challenge in mice

Keywords: HMG-CoA ردوکتاز; Farnesylation; Statin; HMG-CoA reductase; Lipopolysaccharide; Caspase-3; c-Jun NH2-terminal kinase; Liver; Spleen

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Taurine alleviates dyslipidemia and liver damage induced by a high-fat/cholesterol-dietary habit

Keywords: HMG-CoA ردوکتاز; Taurine; Serum lipids; Hepatic lipids; Faecal lipids and bile acid; HMG-CoA reductase; CYP7A1; LDL receptor; GPT; GOT; Hepatic C-reactive protein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Peptide fragmentation as an approach in modeling of an active peptide and designing a competitive inhibitory peptide for HMG-CoA reductase

Keywords: HMG-CoA ردوکتاز; Peptides; Inhibitors; Design; HMG-CoA reductase; β-Turn conformation; Circular dichroism

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Design, synthesis, and docking of highly hypolipidemic agents: Schizosaccharomyces pombe as a new model for evaluating α-asarone-based HMG-CoA reductase inhibitors

Keywords: HMG-CoA ردوکتاز; Alpha-asarone; Docking; HMG-CoA reductase; Hypocholesterolemic activity; Schizosaccharomyces pombe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

The protective effect of simvastatin against low dose streptozotocin induced type 1 diabetes in mice is independent of inhibition of HMG-CoA reductase

Keywords: HMG-CoA ردوکتاز; Simvastatin; Type 1 diabetes; Mevalonic acid; CD-1 mice; HMG-CoA reductase; Lymphocyte function associated antigen-1; Streptozotocin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Influence of bamboo oil supplementation on blood lipid concentration in serum

Keywords: HMG-CoA ردوکتاز; Bamboo oil; HMG-CoA reductase; Cholesterol; Triglyceride; Phospholipid

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه