Keywords: T2DM; type 2 diabetes mellitus; PON; paraoxonase; Hmgcr; hepatic 3-hydroxy-3-methylglutaryl-CoA reductase; Scarb1; scavenger receptor class B member 1; Ahr; aryl hydrocarbon receptor; Lipc; hepatic Lipase; Lcat; lecithin-cholesterol acyltransferase; VLDL;
مقالات ISI (ترجمه نشده)
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Keywords: ACC; acetyl-CoA carboxylase; ADPH; adipophilin; Akt/PKB; protein kinase B; ALOX5; arachidonate 5-lipoxygenase; BTN1A1; butyrophilin subfamily 1 member a1; CIDEA; cell death-inducing DNA fragmentation factor α-like effector A; COX2; cyclooxygenase 2; DGAT
Keywords: NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; FC; free cholesterol; VLDL; very low density lipoprotein; LDL; low density lipoprotein; mTOR; mechanistic target of rapamycin signaling; AMPK; AMP-activated protein kinase; TG; t
Keywords: BB; bevacizumab-bevacizumab; BP; bevacizumab followed by panitumumab; CA9; carbonic anhydrase 9; CRC; colorectal cancer; DEGs; differentially expressed genes; EGFR; epidermal growth factor receptor; EPHA2; ephrin type-A receptor 2; FASN; fatty acid syntha
Keywords: 27-HC; 27-hydroxycholesterol; ER; estrogen receptor; CYP27A1; cytochrome P450, family 27, subfamily A, polypeptide 1; LXR; liver X receptor; BRCA1 and BRCA2; Breast cancer 1 and 2; LDL; low density lipoprotein; HDL; high density lipoprotein; ApoE; apolipo
Keywords: IUGR; intrauterine growth retardation; PNE; prenatal nicotine exposure; TCH; total cholesterol; HDL-C; high-density lipoprotein-cholesterol; LDL-C; low-density lipoprotein-cholesterol; SR-B1; scavenger receptor class B type 1; ABCA1; ATP-binding cassette
Keywords: Acadl; acyl-CoA dehydrogenase, long chain; Acadvl; acyl-CoA dehydrogenase, very long chain; Acaca; acetyl-CoA carboxylase alpha; Abcb11; ATP binding cassette subfamily B member 11; Abcg5; ATP binding cassette subfamily G member 5; Abcg8; ATP binding casse
Keywords: Rare disease; Sterol; Homeostasis; Sterol regulatory element binding protein-2; ABCG8; ATP-binding cassette sub-family G member 8; SREBP-2; Sterol regulatory element-binding protein 2; LDL; low-density lipoprotein; HMGCR; 3-Hydroxy-3-Methylglutaryl-CoA re
Keywords: TCM; Traditional Chinese medicine; YXST; Yangxinshi tablet; SPR; Surface plasmon resonance; PPARγ; Peroxisome proliferator-activated receptor gamma; ACE; Angiotensin-converting enzyme; MAPK; Mitogen-activated protein kinase 14; KEGG; Kyoto Encyclopedia o
Keywords: ACSVL3; acyl-coA synthetase VL3; ALDH1; aldehyde dehydrogenase; ALDOA; aldolase A; ALDOC; aldolase C; AMPK; 5â² AMP-activated protein kinase; ASNS; asparagine synthetase; BTICs; brain tumor initiating cells; 3-BrOP; 3-bromo-2-oxopropionate-1-propyl ester
Keywords: ASBT; apical sodium-dependent bile acid transporter; ASDs; amorphous solid dispersions; BACS; bile acid-CoA synthase; BAT; bile acid-amino acid transferase; BCS; biopharmaceutics classification system; BSH; bile salt hydrolase; C4; 7α-hydroxy-4-cholesten
Keywords: Oxysterols; Cancer; Polymorphism; Risk; Genetics; Cholesterol; 25(OH)D; 25-hydroxyvitamin D; ABC; ATP-binding cassette; AEBS; antiestrogen-binding site; BC; breast cancer; BCR; biochemical recurrence; CETP; cholesteryl ester transfer protein; CH25H; chole
Effect of luteolin on the expression of intestinal cholesterol transporters
Keywords: DMEM; Dulbecco's Modified Eagle Medium; EDTA; ethylenediaminetetraacetic acid; HC; high cholesterol group; HL; HC with 20 mM luteolin at 5 mL/kg body weight group; HMGCR; HMG CoA reductase; HNF4α; hepatocyte nuclear factor 4α; HQ; HC with 20 mM querceti
Keywords: ACADL; acyl-coenzyme A dehydrogenase long-chain; ACSL3; acyl-CoA synthetase long-chain family member 3; BAX; BCL2-associated X; BCL2; B-cell lymphoma 2; BSA; bovine serum albumin; CDS FBS; charcoal:dextran stripped fetal bovine serum; COC; cumulus-oocyte
Keywords: ACC; Acetyl-CoA carboxylase; ADPN; adiponectin; AL; Alentejano; BW; body weight; C; commercial; CB; C diet supplemented with betaine; FA; fatty acid; FASN; Fatty acid synthase; H-FABP; Heart-type fatty acid binding protein; HMGCR; 3-Hydroxy-3-methyl-gluta
Keywords: ALT; alanine aminotransferase; bw; body weight; CESD; cholesteryl ester storage disease; EC; esterified cholesterol; E/L; endosomal/lysosomal; ERT; enzyme replacement therapy; Fas; fatty acid synthase; Hmgcr; hydroxymethylglutaryl coenzyme A reductase; Hm
Keywords: CK; creatine kinase; cN1A; cytosolic 5â²-nucleotidase 1A; DM; dermatomyositis; HMGCR; 3-hydroxy-3-methylglutaryl coenzyme A reductase; IBM; inclusion body myositis; IIM; idiopathic inflammatory myopathy; IMM; immune-mediated myopathy; IVIG; intravenous i
Keywords: Chronic lymphocytic leukemia; Janus kinases; STAT3; Ruxolitinib; Cholesterol; Lipoproteins; Lysosomal lipase; HMGCR; Nuclear receptors;
Keywords: DCFH-DA; 2â²,7â²-Dichlorodihydrofluorescein diacetate; CCCP; carbonyl cyanide m-chlorophenylhydrazone; AMPK; AMP-activated protein kinase; PGC1; Peroxisome proliferator-activated receptor gamma coactivator 1; NOX4; NADPH oxidase 4; SOD2; manganese-depen
Keywords: ALT; alanine transaminase; AST; aspartate transaminase; FBG; fasting blood glucose; GCK; glucokinase; G6Pase; glucose-6-phosphatase; HMGCR; 3-hydroxy-3-methyl-glutaryl-CoA reductase; LBEO; lemon balm essential oil; PPAR; peroxisome proliferator-activated
Keywords: Abcg1; ATP-binding cassette transporter G1; BCA; bicinchoninic acid; C; carbon atoms; Cyp51; lanosterol 14α-demethylase or 14α-sterol demethylase; CypB; cyclophilin B; db; double bonds; Dhcr24; desmosterol reductase or sterol â24-reductase; Elovl 2; e
Keywords: 4-HNE; α,β-unsaturated hydroxyl-alkenal (4-Hydroxynonenal); DCFH; 2â²,7â²-dichlorofluorescin diacetate; DGAT; acyl-coenzyme A: diacylglycerol acyltransferase; FITC; fluorescein-isothiocyanate; HDL; high-density lipoprotein; hLAE; human Lesion Aqueou
Keywords: HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; FTase; farnesyl transferase; GGTase; geranylgeranyl transferase; Statin toxicity; Prenylation; Cholesterol; HMG COA;
Keywords: 7DHC; 7-dehydrocholesterol; ABC transporter; ATP binding cassette transporter; ApoA1; apolipoprotein A1; ApoE; apolipoprotein E; CNS; central nervous system; CYP46A1; cholesterol 24-hydroxylase; CYP51; lanosterol 14 alpha-demethylase; DHCR7; 7-dehydrochol
Keywords: PFOA; perfluorooctanoic acid; ER stress; endoplasmic reticulum stress; 4-PBA; sodium 4-phenylbutyrate; ROS; reactive oxygen species; Cat; catalase; Sod1; superoxide dismutase 1; Sod2; superoxide dismutase 2; Sesn1; sestrin 1; LC3; microtubule-associated p
Keywords: ABC; ATP binding cassette; ADR; adverse drug reactions; ALA; alpha-linolenic acid; ALT; alanine aminotransferase; CVD; cardiovascular disease; AUC; area under the concentration-time curve; Cmax; maximal plasma concentration; CYP; cytochrome P; EGCG; epi
Keywords: CYP7A1; cytochrome P450 family 7 subfamily A polypeptide 1; FXRα; farnesoid X receptor α; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; LDLR; low density lipoprotein receptor; PCSK9; proprotein convertase subtilisin/kexin type 9; SREBP2; sterol regul
Keywords: Abc; ATP-binding cassette transporter; Fasn; fatty acid synthase; GDI; GDP dissociation inhibitor; GP; generalized polarization; HDL; high-density lipoprotein; HFHC; high-fat, high-cholesterol; Hmgcr; 3-hydroxy-3-methyl-glutaryl-CoA reductase; LDL; low-de
Keywords: A2M; alpha-2-macroglobulin; AMACR; alpha-methylacyl-CoA racemase; APOA1; apolipoprotein A-I; AR; androgen receptor; BCL2L1; BCL2-like 1; CAT; catalase; CCNA2; cyclin A2; CCND2; cyclin D2; CCNE1; cyclin E1; CEL; carboxyl ester lipase (bile salt-stimulated
Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation
Keywords: ACAT1; acetyl-CoA cholesterol acyltransferase 1; APOA1; apolipoprotein A1; BHMT; betaine homocysteine methyltransferase; BBB; blood brain barrier; CYP46A1; cholesterol 24-hydroxylase A 1; DNMT1; DNA methyltransferase 1; DNMT3A; DNA methyltransferase 3 A;
Mining Ferula gummosa transcriptome to identify miRNAs involved in the regulation and biosynthesis of terpenes
Keywords: bp; base pair(s); RNA-seq; ribonucleic acid sequencing; KEGG; The Kyoto Encyclopedia of Genes and Genome; BLAST; basic local alignment search tool; TF; transcription factor; TP; terpene synthesis; GO; gene ontology; E-value; expectation value; MVA; mevalo
Roles of microRNA in prostate cancer cell metabolism
Keywords: AMPK; adenosine monophosphate-activated protein kinase; HIF-1α; hypoxia-inducible factor 1-alpha; mTOR; mammalian target of rapamycin; PI3K/AKT; phosphatidylinositol 3-kinase; ATP; adenosine triphosphate; TCA cycle; tricarboxylic acid cycle; GLUTs; gluco
Oral administration of palatinose vs sucrose improves hyperglycemia in normal C57BL/6J mice
Keywords: Palatinose; Hepatic lipogenesis; Cholesterol homeostasis; C57BL/6J mice; Sucrose; ACC; acetyl-CoA carboxylase; ALT; alanine aminotransferase; AST; serum aspartate aminotransferase; AUC; area under the curve; CYP7A1; cholesterol 7 alpha-hydroxylase; FAS; f
CGplus, a standardized herbal composition ameliorates non-alcoholic steatohepatitis in a tunicamycin-induced mouse model
Keywords: Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Hepatotherapeutic; Herbal medicine; ACADL; acyl-CoA dehydrogenase long chain; AMPK; AMP-activated protein kinase; ANOVA; analysis of variance; ALT; alanine transaminase; AST; aspartate tran
Low-expressional IGF1 mediated methimazole-induced liver developmental toxicity in fetal mice
Keywords: IGF-1R; insulin-like growth factor-1 receptor; Akt2; serine-threonine protein kinase 2; HMGCR; HMG CoA reductase; FASN; fatty acid synthase; PEPCK; phosphoenolpyruvate carboxykinase; PCNA; proliferating cell Nuclear antigen; HNF4α; hepatocyte nuclear fac
Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis
Keywords: Actb/ACTB; gene/protein for β-actin; AKT; protein for protein kinase B (AKT/PRKGB); BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; Cyp11a1; gene for cytochrome P450 side chain cleavage enzyme; Cyp17
Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption
Keywords: Cholesterol metabolism; Lipoproteins; Liver; Transcription; Dyslipidemia; ABCA1; ATP-binding cassette transporter A1; ACAT2; acyl-Coenzyme A:cholesterol acyltransferase 2; apo; apolipoprotein; CYP7A1; cholesterol 7α-hydroxylase; HMGCR; 3-hydroxy-3-methyl
Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway
Keywords: Ganoderic Acid A; SREBPs; Obesity; Insulin resistance; Lipid accumulation; ABCA1; ATP-binding cassette transporter 1; ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; BAT; brown adipose tissue; CPT1; carntine palmitoyltransferase 1; CYP7A1; cholesterol
Chronic environmentally relevant levels of simvastatin disrupt embryonic development, biochemical and molecular responses in zebrafish (Danio rerio)
Keywords: Zebrafish; Simvastatin; HMGCR; Chronic effects; Low-level exposures;
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene
Keywords: SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family
Part B: Morphometric and transcriptomic responses to sub-chronic exposure to the polycyclic aromatic hydrocarbon phenanthrene in the fathead minnow (Pimephales promelas)
Keywords: PNPLA2; patatin-like phospholipase domain containing 2; APOE; apolipoprotein E; NPC1; Niemann-Pick disease, type C1; LCAT; lecithin-cholesterol acyltransferase; DGAT1; diacylglycerol O-acyltransferase 1; LRP1; low density lipoprotein-related protein 1 (al
Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice
Keywords: 3αHSD; 3alpha-hydroxysteroid reductase; ABCA1; ATP-binding cassette sub-family A member 1; ABCG1; 4, 5 or 8, ATP-binding cassette sub-family G member 1,4, 5 or 8; ACAT2; acetyl-CoA acetyltransferase (Soat2 gene); ACC1; acetyl-CoA carboxylase (Acaca gene)
Effects of Rosuvastatin on the expression of the genes involved in cholesterol metabolism in rats: adaptive responses by extrahepatic tissues
Keywords: ABCA1; ATP binding cassette subfamily A member 1; ABCG1; ATP binding cassette subfamily G member 1; ApoA1; apolipoprotein A1; HMGCR; 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase; LXR; liver X receptors; PPAR; peroxisome proliferator activated receptor
Alliin attenuates 1, 3-dichloro-2-propanol-induced lipogenesis in HepG2 cells through activation of the AMP-activated protein kinase-dependent pathway
Keywords: SACS; 1,3-DCP; Lipogenesis; AMPK; SREBP; HMGCR;
Lysophosphatidylcholine induces expression of genes involved in cholesterol biosynthesis in THP-1 derived macrophages
Keywords: LPC; lysophosphatidylcholine; PCA; principal component analysis; FFA; free fatty acids; DMSO; dimethyl sulfoxide; FPKM; fragments per kilobase of transcript per million fragments mapped; RT-PCR; reverse transcription polymerase chain reaction; KEGG; Kyoto
Mitophagy in three cases of immune-mediated necrotizing myopathy associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase autoantibodies: ultrastructural and immunohistochemical studies
Keywords: Autoantibody; BNIP3; HMGCR; Mitophagy; Necrotizing myopathy; Programmed cell death;
Atorvastatin alters gene expression and cholesterol synthesis in primary rainbow trout (Oncorhynchus mykiss) hepatocytes
Keywords: Statin drugs; Hepatocytes; Lipid metabolism; HMGCR; Cholesterol; LDL;
Prenatal caffeine ingestion induces long-term alterations in scavenger receptor class B type I expression and glucocorticoid synthesis in adult male offspring rat adrenals
Keywords: Prenatal caffeine ingestion (PCI); Intrauterine growth retardation (IUGR); Scavenger receptor class B type I (SR-BI); Glucocorticoids; Cholesterol supply; Adrenal; ACTH; adrenocorticotropic hormone; CE; cholesteryl esters; GAPDH; glyceraldehyde phosphate
Standardized fraction of Xylocarpus moluccensis fruits improve vascular relaxation and plaque stability in dyslipidemic models of atherosclerosis
Keywords: ABC; ATP-binding cassette; Atorva; atorvastatin; CE; cholesteryl ester; eNOS; endothelial nitric oxide synthase; FC; free cholesterol; HDL; high density lipoprotein; HMGCR; 3-hydroxy-3-methylglutaryl coenzyme A reductase; iNOS; inducible nitric oxide synt
The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain
Keywords: GFAP; glial fibrillary acidic protein; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase-1; PSD95; postsynaptic density protein 95; miRNA; astrocytes; cholesterol; aging; memory;