Keywords: HO-1، heme oxygenase 1; iAs, inorganic arsenic; Cd, cadmium; mRNA, messenger RNA; HO-1, heme oxygenase 1; MT, metallothionein; AQP9, aquaporin-9; ATP7B, Cu2 + transporting ATP-ase; DGT, diffusive gradient in thin film; O2 stress, oxidative stressToxicogenomics; Biomarkers; Real-
مقالات ISI HO-1، heme oxygenase 1 (ترجمه نشده)
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Keywords: HO-1، heme oxygenase 1; EDTA, ethylenediaminetetraacetic acid; eNOS, endothelial nitric oxide synthase; GSH, reduced glutathione; Hb, hemoglobin; HIF, hypoxia-inducible factor; HK-II, hexokinase-2; HO-1, heme oxygenase 1; Hp, haptoglobin; HPAEC, human pulmonary artery endothelia
Interplay between the chalcone cardamonin and selenium in the biosynthesis of Nrf2-regulated antioxidant enzymes in intestinal Caco-2 cells
Keywords: HO-1، heme oxygenase 1; ARE, antioxidant response element; GPx, glutathione peroxidase; HO-1, heme oxygenase 1; MeHg, methylmercury; Nrf2, nuclear factor erythroid 2-related factor 2; PSTK, O-phosphoseryl-tRNA(Sec) kinase; Sec, selenocysteine; SepSecS, O-phosphoseryl-tRNA(Sec) s
Nrf2 silencing to inhibit proteolytic defense induced by hyperthermia in HT22 cells
Keywords: HO-1، heme oxygenase 1; ARE, Antioxidant Response Element; DNPH, 2,4-Dinitrophenylhydrazine; GAPDH, Glyceraldehyde 3-Phosphate Dehydrogenase; GCL, Glutamate Cysteine Ligase; GST, Glutathione S-Transferase; HDAC, Histone Deacetylase; HO-1, Heme Oxygenase 1; HSP, Heat Shock Protei
3-(2-Oxo-2-phenylethylidene)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one (compound 1), a novel potent Nrf2/ARE inducer, protects against DSS-induced colitis via inhibiting NLRP3 inflammasome
Keywords: HO-1، heme oxygenase 1; ARE, antioxidant responsive element; BMDM, bone-marrow derived macrophages; CAC, colitis-associated colon cancer; DSRs, damage sensing receptor; DSS, dextran sulfate sodium; GSTs, glutathione S-transferases; HO-1, heme oxygenase 1; IBD, inflammatory bowel
Metallothionein blocks oxidative DNA damage induced by acute inorganic arsenic exposure
Keywords: HO-1، heme oxygenase 1; ABCC1, Multidrug resistance-related protein 1; ABCC2, Multidrug resistance-related protein 2; As, Arsenic; DMPO, 5,5-Dimethyl-1-pyrroline N-oxide; GST, Glutathione S-transferase; GSTα2, Glutathione S-transferase-α2; HO-1, Heme oxygenase 1; H2O2, Hydrogen
Keap1–Nrf2 signalling in pancreatic cancer
Keywords: HO-1، heme oxygenase 1; AKR1B10, Aldo–keto reductase family 1 b10; ARE, antioxidant response element; Bach1, BTB and CNC homology 1; CNC, Cap ‘n’ collar; Cul3, Cullin-3; ER, endoplasmic reticulum; GCLC, glutamate–cysteine ligase catalytic; HO-1, heme oxygenase 1; Keap1, Kelch-li
Bicyclol upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia
Keywords: HO-1، heme oxygenase 1; Nrf2, nuclear factor erythroid 2-related factor 2; HO-1, heme oxygenase 1; SOD1, superoxide dismutase 1; MDA, malondialdehyde; I/R, ischemia/reperfusion; pMCAO, permanent middle cerebral artery occlusion; MCAO, middle cerebral artery occlusion; By, bicycl
Redox status in mammalian cells and stem cells during culture in vitro: Critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance
Keywords: HO-1، heme oxygenase 1; Oxygen; Glutathione; Cystine transporter; xCT; Nrf2; Feeder cells; 2-Mercaptoethanol; CD36; Lymphocytes; Embryonic stem cells; iPS cellsBCS, bathocuproine sulfonate; ES cells, embryonic stem cells; HO-1, heme oxygenase 1; Prx1, peroxiredoxin 1; SQSTM1, se
Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin
Keywords: HO-1، heme oxygenase 1; ERK, extracellular signal-related kinase; γGCS, γ-glutamylcysteine synthetase; GSH, glutathione; HO-1, heme oxygenase 1; Keap1, Kelch-like ECH associating protein 1; m-CPBA, meta-chloroperoxybenzoic acid; Nrf2, Nuclear factor (erythroid-derived 2)-like 2;
Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: Role of Nrf2-dependent gene expression and antioxidant enzymes
Keywords: HO-1، heme oxygenase 1; CAT, catalase; cl. casp-3, cleaved caspase-3; γGCS, γ-glutamylcysteine-synthetase; GSH, glutathione; H&E, hematoxylin and eosin; HO-1, heme oxygenase 1; NQO1, NAD(P)H quinone oxidoreductase 1; Nrf2, nuclear factor erythroid-2 related factor 2; PEITC, phen
Effect of quercetin on inflammatory gene expression in mice liver in vivo – role of redox factor 1, miRNA-122 and miRNA-125b
Keywords: HO-1، heme oxygenase 1; AOAH, acyloxyacyl hydrolase; ALDOA, aldolase A; ALT, alanine transaminase; AST, aspartate transaminase; CRP, C-reactive protein; HO-1, heme oxygenase 1; IL6, interleukin 6; MCP-1, monocyte chemoattractant protein-1; miR, micro RNA; Ref-1, redox factor-1;
Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT3
Keywords: HO-1، heme oxygenase 1; VSMC, vascular smooth muscle cell; TP, Thymidine phosphorylase; HO-1, heme oxygenase 1; JAK/STAT, janus-activated kinase/signal transducers and activators of transcription; SFK, Src family kinase; FCS, fetal calf serum; C2, TP overexpressing cell clone nu
Induction of activation of the antioxidant response element and stabilization of Nrf2 by 3-(3-pyridylmethylidene)-2-indolinone (PMID) confers protection against oxidative stress-induced cell death
Keywords: HO-1، heme oxygenase 1; Keap1, kelch-like ECH-associated protein 1; Nrf2, nuclear factor (erythroid-derived 2)-like 2; Cul3, Cullin-3; ARE, antioxidant response element; GSH, glutathione; SOD, superoxide dismutase; HO-1, heme oxygenase 1; NQO1, NAD(P)H:quinone oxidoreductase 1;
Cadmium-induced teratogenicity: Association with ROS-mediated endoplasmic reticulum stress in placenta
Keywords: HO-1، heme oxygenase 1; ATF6, activating transcription factor 6; Cd, cadmium; CHOP, CCAAT/enhancer binding protein (C/EBP) homologous protein; ER, endoplasmic reticulum; GSH, Glutathione; HO-1, heme oxygenase 1; iNOS, inducible nitric oxide synthase; NT, nitrotyrosine; PBN, alph
Heme oxygenase 1 is induced by miR-155 via reduced BACH1 translation in endothelial cells
Keywords: HO-1، heme oxygenase 1; ARE, antioxidant-response element; AT1R, angiotensin II type 1 receptor; EBM, endothelial cell basal medium; ET-1, endothelin 1; FBS, fetal bovine serum; DMEM, Dulbecco's modified Eagle medium; HO-1, heme oxygenase 1; HUVEC, human umbilical vein endotheli
Benzylidenemalononitrile compounds as activators of cell resistance to oxidative stress and modulators of multiple signaling pathways. A structure–activity relationship study
Keywords: HO-1، heme oxygenase 1; ARE, antioxidant response element; BMN, benzylidenemalononitrile(s); ELSD, evaporative light scattering detection; ESI, electrospray ionization; GSH, glutathione; HO-1, heme oxygenase 1; IL-8, interleukin 8; LC–MS, liquid chromatography mass spectrometry;
l-Glyceraldehyde 3-phosphate reductase from Escherichia coli is a heme binding protein
Keywords: HO-1، heme oxygenase 1; Gpr, l-glyceraldehyde 3-phosphate reductase from Escherichia coli; l-GAP, l-glyceraldehyde 3-phosphate; AKR, aldo–keto reductase; Kvβ, voltage-gated potassium channel β-subunit; MALDI, matrix-assisted laser desorption/ionization; HO-1, heme oxygenase 1; C
Sulforaphane protects brains against hypoxic–ischemic injury through induction of Nrf2-dependent phase 2 enzyme
Keywords: HO-1، heme oxygenase 1; ANOVA, analysis of variance; HI, hypoxic–ischemic; HO-1, heme oxygenase 1; MDA, malondialdehyde; Nrf2, NF-E2-related factor-2; PBS, phosphate-buffered saline; ROS, reactive oxygen species; SFN, sulforaphane; TTC, 2,3,5-triphenyltetrazolium chloride; TUNEL
Peripheral nerve and brain differ in their capacity to resolve N,N-diethyldithiocarbamate-mediated elevations in copper and oxidative injury
Keywords: HO-1، heme oxygenase 1; TBS, tris buffered saline; GST-α, glutathione transferase alpha; BSA, bovine serum albumin; DEDC, N,N-diethyldithiocarbamate; HO-1, heme oxygenase 1; CCS, copper chaperone for superoxide dismutase 1; SOD1, superoxide dismutase 1Dithiocarbamate; Copper eli
Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells
Keywords: HO-1، heme oxygenase 1; 3-MC, 3-methylcholanthrene; CYP, cytochrome P450; DMSO, dimethylsulfoxide; EROD, 7-ethoxyresorufin O-deethylation; FCS, fetal calf serum; GSH, glutathione; GST, glutathione S-transferase; HAA, heterocyclic aromatic amines; HO-1, heme oxygenase 1; MeIQx, 2
Arsenic promotes angiogenesis in vitro via a heme oxygenase-1-dependent mechanism
Keywords: HO-1، heme oxygenase 1; HMVECs, human microvascular endothelial cells; HO-1, heme oxygenase 1; Bach1, BTB and CNC homolog 1; Nrf2, nuclear factor erythroid-derived 2 related factor 2; Maf, musculoaponeurotic fibrosarcoma; MARE, Maf recognition element; VEGF, vascular endothelial
Chlorobenzene induces oxidative stress in human lung epithelial cells in vitro
Keywords: HO-1، heme oxygenase 1; GSTP1, glutathione S-transferase pi; HO-1, heme oxygenase 1; GSH, glutathione; ROS, reactive oxygen species; VOC, volatile organic compoundChlorobenzene; Volatile organic compound (VOC); Glutathione S-transferase π1 (GSTP1); Heme oxygenase 1 (HO-1); Super
“Venopathy” at work: recasting neointimal hyperplasia in a new light
Keywords: HO-1، heme oxygenase 1; ACE, angiotensin-converting enzyme; AVF, arteriovenous fistulae; AVG, arteriovenous graft; BMP-7, Bone morphogenic protein-7; CD40L, CD40 ligand; End-MT, endothelial-mesenchymal transition; Hcy, homocysteine; HO-1, heme oxygenase 1; IEL, internal elastic
Identification and characterization of hypoxia-induced genes in Carassius auratus blastulae embryonic cells using suppression subtractive hybridization
Keywords: HO-1، heme oxygenase 1; SSH, suppression subtractive hybridization; CAB cells, Carassius auratus blastulae embryonic cells; ERO1-L, endoplasmic reticulum oxidoreductin 1 like; p53, tumor protein p53; CPO, coproporphyrinogen oxidase; HO-1, heme oxygenase 1; MKP2, MAPK phosphatase
The Right Ventricle Under Pressure : Cellular and Molecular Mechanisms of Right-Heart Failure in Pulmonary Hypertension
Keywords: HO-1، heme oxygenase 1; pulmonary arterial hypertension; pulmonary vascular resistance; right ventricleACE, angiotensin converting enzyme; ATII, angiotensin II; ECM, extracellular matrix; ET-1, endothelin-1; HO-1, heme oxygenase 1; IL, interleukin; LV, left ventricle/ventricular
Protective effects of peroxiredoxin-1 at the injured blood–brain barrier
Keywords: HO-1، heme oxygenase 1; 7AAD, 7-amino actinomycin D; BBB, blood–brain barrier; EAE, experimental autoimmune encephalomyelitis; ECs, endothelial cells; ECIS, electrical cell substrate impedance sensing; FCS, fetal calf serum; HO-1, heme oxygenase 1; MS, multiple sclerosis; Nrf2,
Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver
Keywords: HO-1، heme oxygenase 1; AFB1, aflatoxin B1; AFBO, AFB1-8,9-epoxide; Nrf2, nuclear factor-erythroid 2 p45-related factor 2; C+K, cafestol and kahweol; GCL, Glutamate cysteine Ligase; GSH, Reduced glutathione; GST, Glutathione S-transferase; HO-1, Heme oxygenase 1; NQO, NAD(P)H:qu
Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme
Keywords: HO-1، heme oxygenase 1; ROS, reactive oxygen species; HO-1, heme oxygenase 1; NQO1, NAD(P)H quinone oxidoreductase 1; GR, glutathione reductase; GPx, glutathione peroxidase; Nrf2, NF-E2-related factor-2; Keap1, Kelch-like ECH-associated protein 1; MTT, 3-(4,5-dimethylthiazol-2-y
A novel approach to screening for new neuroprotective compounds for the treatment of stroke
Keywords: HO-1، heme oxygenase 1; ARE, antioxidant response element; DMEM, Dulbecco's modified Eagle's medium; EGCG, epigallocatechin gallate; FCS, fetal calf serum; GSH, glutathione; HO-1, heme oxygenase 1; IAA, iodoacetic acid; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium
Baicalein inhibition of hydrogen peroxide-induced apoptosis via ROS-dependent heme oxygenase 1 gene expression
Keywords: HO-1، heme oxygenase 1; BE, baicalein; BI, baicalin; ERK, extracellular regulated kinases; JNK, c-Jun N-terminal kinases; HO-1, heme oxygenase 1; NAC, N-acetyl cysteine; CHX, cycloheximide; Act D, actinomycin D; H2O2, hydrogen peroxide; ROS, reactive oxygen species; MTT, (3-(4,5
p8 Upregulation sensitizes astrocytes to oxidative stress
Keywords: HO-1، heme oxygenase 1; p38 MAPK, p38 mitogen-activated protein kinase; HO-1, heme oxygenase 1; NQO-1, NAD(P)H dehydrogenase quinone 1; SOD-2, superoxide dismutase 2Astrocytes; DNA arrays; p8; Oxidative stress; Heme oxygenase 1; p38 MAPK
Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents
Keywords: HO-1، heme oxygenase 1; ARE, antioxidant responsive element; CCA, common carotid artery; HO-1, heme oxygenase 1; MCA, middle cerebral artery; Nrf2, nuclear factor E2-related factor-2; qPCR, quantitative polymerase chain reaction; SUL, sulforaphaneBrain ischemia; Heme oxygenase;
Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6
Keywords: HO-1، heme oxygenase 1; BE, baicalein; BI, baicalin; LPS, lipopolysaccharide; TPA, 12-O-tetradecanoylphorbol 13-acetate; H2O2, hydrogen peroxide; HO-1, heme oxygenase 1; HSP70, heat shock protein 70; HSP90, heat shock protein 90; HO-2, heme oxygenase 2; LDH, lactate dehydrogenas
Quercetin inhibition of ROS-dependent and -independent apoptosis in rat glioma C6 cells
Keywords: HO-1، heme oxygenase 1; HO-1, Heme oxygenase 1; LPS, Lipopolysaccharide; SnPP, Tin protoporphyrin; iNOS, Inducible nitric oxide synthase; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; NBT, Nitroblue tetrazolium; BCIP, 5-bromo-4-chloro-3-indolyl phosphate; Z