دانلود مقالات ISI درباره Hts + ترجمه فارسی

3D bioprinting - Flow cytometry as analytical strategy for 3D cell structures

Keywords: 7-AAD; 7-Aminoactinomycin D; HMI; Human-Machine Interface; 3D; three-dimensional; HTPD; high-throughput process development; HTS; high-throughput screening; FSC-A; Forward scatter peak area; FSC-H; Forward scatter peak height; SSC-A; side scatter peak are

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

New perspectives for pharmacological chaperoning treatment in methylmalonic aciduria cblB type

Keywords: AdoCbl; adenosylcobalamin; ATR; ATP:cob(I)alamin adenosyltransferase; DSF; differential scanning fluorimetry; HGMD; Human Gene Mutation Database; HTS; high-throughput screening; iPSCs; induced pluripotent stem cells; MMA; methylmalonic aciduria; MUT; meth

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Analysis of Genes Associated With Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn's Disease

Keywords: Inflammatory Bowel Disease; Candidate Gene Approach; Mendelian Disorder; Complex Trait; CD; Crohn's disease; ELISA; enzyme-linked immunosorbent assay; eQTL; expression quantitative trait loci; GWAS; genome-wide association study; HTS; high-throughput seq

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Proteomic analyses for profiling regulated proteins/enzymes by Fucus vesiculosus fucoidan in B16 melanoma cells: A combination of enzyme kinetics functional study

Keywords: 2-DE; two-dimensional electrophoresis; MALDI-TOF; matrix-assisted laser desorption/ionization time-of-flight; IPG; immobilized pH gradient; HTS; high-throughput screening; Fucoidan; B16 melanoma cell; Proteomics;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic

Keywords: ANO; Anoctamin; BSA; bovine serum albumin; CaCC; calcium (Ca2+)-activated Cl- channel; CF; cystic fibrosis; CFBE; cystic fibrosis bronchial epithelial (cells); CFTR; cystic fibrosis transmembrane conductance regulator; Dox; doxycycline; ER; endoplasmic re

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Cell cultures in drug discovery and development: The need of reliable in vitro-in vivo extrapolation for pharmacodynamics and pharmacokinetics assessment

Keywords: 3Rs; Reduction, Replacement, Refinement; PBPK; physiologically based pharmacokinetic; 2D; two-dimensional; 3D; three-dimensional; HTS; high-throughput screening; IVIVE; in vitro-in vivo extrapolation; ADME; absorption, distribution, metabolism and excreti

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Combining mouse embryonic stem cells and zebrafish embryos to evaluate developmental toxicity of chemical exposure

Keywords: α/β-Cardiac Myosin; Heavy chain Alpha and Beta Cardiac Myosin; ABCG2; ATP-Binding Cassette sub-family G member 2; ANOVA; Analysis of Variance; DMEM; Dulbecco's Modified Eagle Medium; DMSO; Dimethyl Sulfoxide; DPBS; Dulbecco's Phosphate-Buffered Sali

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Investigation of yeast population diversity and dynamics in spontaneous fermentation of Vidal blanc icewine by traditional culture-dependent and high-throughput sequencing methods

Keywords: Icewine; Yeast; Diversity; Dynamics; Spontaneous fermentation; Culture-dependent and -independent approaches; Frequent and infrequent species; WL nutrient agar; Wallerstein laboratory nutrient agar; HTS; High-throughput sequencing; ITS region; Internal tr

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model

Keywords: AUCu; unbound area-under-the-curve; (S)-BINAP; (S)-(-)-(1,1′-binaphthalene-2,2′-diyl)bis(diphenylphosphine); CLu; unbound systemic clearance rate; Compd; compound; DIEA; N,N-diisopropyl ethylamine, EtOAc, ethyl acetate; FFA2 receptor; free fatty acid-

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Deciphering the role of IspD (2‑C‑methyl‑D‑erythritol 4‑phosphate cytidyltransferase) enzyme as a potential therapeutic drug target against Plasmodium vivax

Keywords: IspD; (2‑C‑methyl‑d-erythritol 4-phosphate cytidyltransferase); PvIspD; Plasmodium vivax IspD; PfIspD; Plasmodium falciparum IspD; AtIspD; Arabidopsis thaliana IspD; MEP; Methyl erythritol phosphate (Non-mevalonate); HTS; High Throughput Screening;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition

Keywords: Idebenone (PubChem CID: 3686); acarbose (PubChem CID: 41774); BI78D3 (PubChem CID: 2747117); candesartan cilexetil (PubChem CID: 2540); PQ401 (PubChem CID: 9549305); Src I1 (PubChem CID: 1474853); 17a-Hydroxyprogesterone (PubChem CID: 6238); FPA 124 (PubC

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma

Keywords: Organoid; AUY922; Bile Duct Cancer; DNAJB5; CCA; cholangiocarcinoma; DMSO; dimethyl sulfoxide; FFPE; formalin-fixed paraffin-embedded; FGFR; fibroblast growth factor receptor; GI; growth inhibition; HSP; heat shock protein; HTS; high-throughput screen; iC

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

Use of biorelevant dissolution and PBPK modeling to predict oral drug absorption

Keywords: Biorelevant dissolution; Weak base; PBPK modeling; BCS class II; pH dependent solubility; ACAT; advanced compartmental absorption and transit model; ADAM; advanced dissolution, absorption and metabolism model; API; active pharmaceutical ingredient; ASD;

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2018 سفارش ترجمه

Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR

Keywords: Natural products; Nuclear receptors; Liver X receptor; Farnesoid X receptor; Retinoid X receptor; Metabolic syndrome; Precision medicine; 6-ECDCA; 6α-ethyl-chenodeoxycholic acid (obeticholic acid); AA; arachidonic acid; ABC; ATP-binding cassette transpor

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2018 سفارش ترجمه

A series of novel indazole derivatives of Sirt 1 activator as osteogenic regulators

Keywords: Sirt 1; Osteoporosis; Osteogeneration; Indazole; HTS;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Human pegivirus-1 in the CSF of patients with HIV-associated neurocognitive disorder (HAND) may be derived from blood in highly viraemic patients

Keywords: HAND; HIV-associated neurocognitive disorder; HTS; high throughput sequencing; CSF; cerebrospinal fluid; HPgV1; human pegivirus-1; ART; antiretroviral therapy; CNS; central nervous system; ddPCR; digital droplet PCR; 5′NCR; 5′ non coding regione; Huma

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Improvement of Ka-band satellite link availability for real-time IP-based video contribution

Keywords: HTS; IP video streaming; Ka-band; Network availability; Propagation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Herb-drug interaction potential of Berberis aristata through cytochrome P450 inhibition assay

Keywords: CYP450; cytochrome P450; HTS; high-throughput screening; IC50; the 50% inhibitory concentration; RP-HPLC; reverse phase high-performance liquid chromatography; CYP450-CO; cytochrome P450- carbon monoxide; RLM; rat liver microsome; CI; combination index; H

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of a compound isolated from German chamomile (Matricaria chamomilla) with dermal sensitization potential

Keywords: ACN; Acetonitrile; DBN; 1,5-Diazabicyclo[4.3.0]non-5-ene; DCYA; Dansyl CYsteamine; DNE; 1,6-Dioxaspiro[4.4]non-3-en-2-one; DMSO; Dimethyl sulfoxide; DPRA; Direct Peptide Reactivity Assay; ESI; Electro spray ionization; HTS; High throughput screening; LLNA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Long noncoding RNA activated by TGF-β in human cancers: A meta-analysis

Keywords: ATB; activated by TGF-β; HR; hazard ratio; CI; confidence interval; OR; odds ratio; CRC; colorectal cancer; NSCLC; non-small cell lung cancer; PRC; pancreatic cancer; GC; gastric cancer; RCC; renal cell carcinoma; PSC; prostate carcinoma; HCC; hepatocell

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Test results of 12/18 kA ReBCO coated conductor current leads

Keywords: HTS; high temperature superconductor; LTS; low temperature superconductor; CC; coated conductor; 2G; second generation; CL; current lead; LN2; liquid nitrogen; GN2; gaseous nitrogen; SHe; supercritical helium; LHC; large hadron collider; HEP; high energy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

High-throughput screening of hybridoma supernatants using multiplexed fluorescent cell barcoding on live cells

Keywords: HTS; high-throughput screening; MFCB; multiplexed fluorescent cell barcoding; FCB; fluorescent cell barcoding; mAbs; monoclonal antibodies; CFSE; carboxyfluorescein succinimidyl ester; 5-TAMRA; 5-Carboxytetramethylrhodamine; APC; allophycocyanin; V; Viole

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus

Keywords: Zika flavivirus; NS2B/NS3 serine protease; Small molecule inhibitor; apo ZIKV NS2B-NS3pro structure; ZIKV; Zika flavivirus; HCV; hepatitis C virus; DENV; Dengue virus; WNV; West Nile virus; SPR; surface plasmon resonance; HTS; high-throughput screening;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells

Keywords: HTS; high throughput screening; ECs; endothelial cells; DA; dorsal aorta; PCV; posterior cardinal vein; hpf; hours post fertilization; ISVs; intersegmental vessels; DLAV; dorsal longitudinal anastomotic vessel; CV; caudal vein; CVP; caudal vein plexus; pV

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of pyrazolopyrimidine derivatives as novel inhibitors of ataxia telangiectasia and rad3 related protein (ATR)

Keywords: ATR; Pyrazolopyrimidine; DNA damage; PI3K; HTS;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Visible-photo catalytic performance and screening of sulfide-loaded g-C3N4 composites in an aqueous reaction

Keywords: Ratio; Photo-catalyst; HTS; g-C3N4; Metal sulfide;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Analyses of decay heat removal tests with PRACS and DRACS of a sodium loop using the NETFLOW++ code

Keywords: AC; air cooler; CFD; computational fluid dynamics; DHX; direct heat exchanger; DRACS; direct reactor auxiliary cooling system; FBR; fast breeder reactor; HTS; heat transport system; IHX; intermediate heat exchanger; IRACS; intermediate reactor auxiliary c

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Investigation of cryogenic level sensors for LN2 and LOX

Keywords: HTS; Liquid level sensors calibration; Discrete diode array; Capacitance level sensor; Cryogenics;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Keywords: ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and evaluation of 5-(arylthio)-9H-pyrimido[4,5-b]indole-2,4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents

Keywords: Multiple receptor tyrosine kinase inhibitors; Antiangiogenic agents; Pyrimido[4,5-b]indole synthesis; Thymidylate synthase inhibitors; Combination chemotherapeutic potential in single agents; RTK; receptor tyrosine kinases; VEGF; vascular endothelial grow

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

(Re-)programming of subtype specific cardiomyocytes

Keywords: ADSC; adipose tissue-derived mesenchymal stem cell; Alcam; activated leukocyte cell adhesion molecule; AMI; acute myocardial infarction; ANF; natriuretic factor; AP; action potential; ASC; adult stem cell; AV; atrioventricular; AVB; atrioventricular bundl

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Mycoloyltransferases: A large and major family of enzymes shaping the cell envelope of Corynebacteriales

Keywords: aa; amino acids; AG; arabinogalactan; Ag85; antigen 85; DEP; diethyl phosphate; DTT; dithiothreitol; ESI-MS; ElectroSpray Ionisation- Mass Spectrometry; Fbp(s); fibronectin-binding protein(s); FITC; fluorescein isothiocyanate; HTS; high throughput screeni

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

HIVE-heptagon: A sensible variant-calling algorithm with post-alignment quality controls

Keywords: NGS; HTS; Variant-calling; Post-alignment quality control; SNP; Genome assembly;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Lipidomics in translational research and the clinical significance of lipid-based biomarkers

Keywords: 5-HETE; 5-hydroxyicosatetraenoic acid; 12-HETE; 12-hydroxyicosatetraenoic acid; 15-HETE; 15-hydroxyicosatetraenoic acid; aa; diacyl; ae; acyl-alkyl; ACs; acylcarnitines; ACOG; The American College of Obstetricians and Gynecologists; AD; Alzheimer's dise

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Investigating the regulatory roles of the microRNAs and the Argonaute 1-enriched small RNAs in plant metabolism

Keywords: AGO1; Argonaute 1; miRNA; microRNA; sRNA; small RNA; siRNA; small interfering RNA; PMN; Plant Metabolic Network; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; SPL; Squamosa promoter binding Protein-Like; HTS; high-throughput sequencing

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Targeted pharmacotherapies for defective ABC transporters

Keywords: 4-PBA; 4-phenylbutyrate; ABC; ATP-Binding Cassette; BRIC2; Benign Recurrent Intrahepatic Cholestasis type 2; BSEP; Bile Salt Export Pump; CF; Cystic Fibrosis; CFTR; Cystic Fibrosis Transmembrane conductance Regulator; CsA; Cyclosporin A; DMSO; DiMethylSul

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies

Keywords: Ap3A; diadenosine triphosphate; Ap4A; diadenosine tetraphosphate; Ap5A; diadenosine pentaphosphate; AR-C67085MX; 2-propylthio-β,γ-dichloromethylene-ATP; PSB0412; 2-propargylthio-β,γ-dichloromethylene-ATP; 5-BDBD; 5-(3-bromophenyl)-1,3-dihydro-2H-benzo

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of a Potential Molecular Diagnostic Biomarker in Keloid Disease: Syndecan-1 (CD138) Is Overexpressed in Keloid Scar Tissue

Keywords: DFSP; dermatofibrosarcoma protuberan; HTS; hypertrophic scars; KS; keloid scars; NS; normal scar;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Design and Performance Analysis of an Iron Core-based No-Insulation HTS Magnet for HTS DC Induction Heating Machine

Keywords: Cryogenic; FEM; HTS; Induction heating; Iron core; No insulation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery and development of benzo-[1,2,4]-triazolo-[1,4]-oxazepine GPR142 agonists for the treatment of diabetes

Keywords: GPR142; g-protein coupled receptor 142; HTS; high throughput screen; PPB; plasma protein binding; CYP; cytochrome P450; GPR142; Diabetes; Wild-type knock-out study;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Modeling AC ripple currents in HTS coated conductors by integral equations

Keywords: AC losses; AC ripples; Finite-element method; Numerical models; HTS;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

ESI-IMS-MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules

Keywords: Aβ; amyloid-β peptide; Aβ40; amyloid-β peptide residues 1-40; AD; Alzheimer's disease; ADH; alcohol dehydrogenase; AFM; atomic force microscopy; CCS; collision-cross sectional area; Cl-NQTrp; chloronaphthoquinine-tryptophan; CsI; caesium iodide; D

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Original ArticleWound HealingPreventing Scars after Injury with Partial Irreversible Electroporation

Keywords: DOP; degree of polarization; HTS; hypertrophic scarring; IRE; irreversible electroporation; pIRE; partial irreversible electroporation; PS-OCT; polarization-sensitive optical coherence tomography; ROI; region of interest;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Optimizing multi-dimensional high throughput screening using zebrafish

Keywords: hpf; hours post fertilization; DMSO; Dimethyl sulfoxide; HTS; high-throughput screening; Zebrafish; High throughput screening; Developmental toxicity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

A high-throughput screening system targeting the nuclear export pathway via the third nuclear export signal of influenza A virus nucleoprotein

Keywords: IAV; influenza virus; NP; nucleoprotein; vRNA; viral RNA; vRNP; viral ribonucleoprotein; NLS; nuclear localization signal; NES; nuclear export signal; CRM1; chromosome region maintenance 1; LMB; leptomycin B; HTS; high-throughput screening; AcGFP; green f

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Original ArticleConnective TissueLongitudinal, 3D Imaging of Collagen Remodeling in Murine Hypertrophic Scars In Vivo Using Polarization-Sensitive Optical Frequency Domain Imaging

Keywords: DOP; degree of polarization; HTS; hypertrophic scars; LR; local retardation; OCT; optical coherence tomography; PS; polarization-sensitive; PS-OFDI; polarization-sensitive optical frequency domain imaging;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Synergistic effect of vitamin D and low concentration of transforming growth factor beta 1, a potential role in dermal wound healing

Keywords: αSMA; alpha smooth muscle actin; COL1; type 1 collagen; CTGF; connective tissue growth factor; ECM; extracellular matrix; FN1; fibronectin 1; HPRT; hypoxanthine-guaninephosphoribosyltransferase gene; HTS; hypertrophic scar (s); siRNA; small interfering R

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators

Keywords: ACC; acetyl-CoA carboxylase; ADaM; allosteric drug and metabolite; AID; auto-inhibitory domain; α-RIM; α-regulatory interacting motif; AMPK; adenosine monophosphate-activated protein kinase; ASMS; affinity selection mass spectrometry; CamKKβ; Ca2+/calm

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Mechanisms of allergy and clinical immunologyPersistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy

Keywords: Aeroallergens; allergen-specific antibodies; clonotype evolution; IgE; immunoglobulin class-switch; local immunity; repertoire; specific immunotherapy; HTS; High-throughput sequencing; IGHV; Immunoglobulin heavy chain variable; scFv; Single-chain fragment

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Screening and characterization of molecules that modulate the biological activity of IFNs-I

Keywords: APA; antiproliferative assay; AVA; antiviral assay; C+; positive control; C-; negative control; CC; compound control; CWT; cells without treatment; DMSO; dimethyl sulfoxide; EGFP; enhanced green fluorescent protein; EnE; enhancer effect; FCS; fetal calf s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه