Keywords: Atherosclerosis; Cardiovascular diseases; Cell cycle; Proliferation; Pulmonary hypertension; Restenosis; Signaling pathway; Vascular smooth muscle cells; ACE; angiotensin converting enzyme; aFGF; acidic FGF; Ang II; angiotensin II; AP-1; activating protei
مقالات ISI (ترجمه نشده)
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Keywords: ADM; acinar-to-ductal metaplasia; BMP; bone morphogenetic protein; GERD; gastroesophageal reflux disease; HIF; hypoxia inducible factor; IESC; intestinal epithelial stem cell; IGF1R; insulin-like growth factor 1 receptor; MDSC; myeloid-derived suppressor
Keywords: GDM; gestational diabetes mellitus; GLUT; glucotransporter; IR; insulin receptor; IGF; insulin growth factor; IGF1R; insulin-like growth factor 1 receptor; GTT; glucose tolerance test; ITT; insulin tolerance test; AUC; area under the curve.; Obesity; Ovar
Keywords: KME; aqueous extract of Korean mistletoe; EMG; electromyography; FoxO1; forkhead box protein O1; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GSK3; glycogen synthase kinase 3; IGF; insulin growth factor; IR; insulin receptor; IRS1; insulin receptor su
Keywords: AIs; aromatase inhibitors; AMPK; Adenosine Monophosphate-Activated Protein Kinase; AR; androgen; ATM; Ataxia Telangiectasia Mutated; ATP; Adenosine Triphosphate; BCSS; breast cancer specific survival; CK-MB; Creatine Kinase-MB; CREB1; cAMP Response Elemen
Keywords: ADHD; attention deficit hyperactivity disorder; APOE; apolipoprotein E gene; AR; androgen receptor gene; bdnf; brain derived neurotrophic factor; CAH; congenital adrenal hyperplasia; CAIS; complete androgen insensitivity syndrome; COMT; catechol-O-methylt
Keywords: NF2; neurofibromin 2; ZIC; Zinc finger protein; MCM; minichromosome maintenance; EGFL6; EGF-like domain multiple 6; LMO3; LIM domain only 3; IGF1R; Insulin like growth factor 1 receptor; GO; Gene ontology; FDR; false discovery rate; KEGG; Kyoto Encycloped
Keywords: ABCA1; ATP-binding cassette transporter 1; ABCG1; ATP Binding Cassette G1; AMPK; 5â²AMP-activated protein kinase; AP-1; activator protein 1; apo A-I; apolipoproteins A-I; AT; adipose tissue; CCK-1; cholecystokinin; CD; Crohn's disease; CVD; cardiovascula
Keywords: AAV; adeno-associated virus; BDNF; brain-derived neurotrophic factor; CNP; 2â²,3â²-cyclic nucleotide 3â²-phosphodiesterase; CNS; central nervous system; CNTF; ciliary neurotrophic factor; CNTFRα; ciliary neurotrophic factor receptor alpha; Cop-1; copa
Keywords: Ab; Antibody; ABC; ATP-binding cassette; AIOM; Associazione Italiana di Oncologia Medica; ALCAM; Activated leukocyte cell adhesion molecule; APOD; Apolipoprotein D; AR; androgen receptor; AURKA; Aurora kinase A; AURKB; Aurora kinase B; BCS; Biopharmaceuti
Keywords: ANXA2; annexin A2; ANXA5; annexin A5; AUC; area under the curve; C1QB; complement component 1, q subcomponent, B chain; C5; complement component 5; CD46; complement regulatory protein; CDC; Centers for Disease Control and Prevention; CFH; complement facto
Keywords: Arc; activity-regulated cytoskeleton-associated protein; IGF1R; insulin-like growth factor 1 receptor; IGF2; insulin-like growth factor 2; IGF2R; insulin-like growth factor 2 receptor; LTM; long-term memory; mBDNF; mature brain-derived neurotrophic factor
Keywords: IGF-I; IGF1R; Insulin receptor; IGFBP; New World Monkeys; Molecular evolution
Keywords: DAPI; 4â²,6-diamidino-2-phenylindole; YC-1; 5-[1-(phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol; IGF1R; insulin-like growth factor 1 receptor; IGFBP3; insulin-like growth factor-binding protein 3; phospho-IGF1R; phospho-insulin-like growth factor 1; HIF
Keywords: EGFR; epidermal growth factor receptor; NSCLC; non-small cell lung cancer; TKI; tyrosine kinase inhibitor; WT; wild type; KRAS; Kirsten RNA associated rat sarcoma 2 virus gene; PTEN; phosphatase and tensin homolog; HGF; hepatocyte growth factor; IGF1R; in
Keywords: ACE; angiotensin I converting enzyme; AGT; angiotensinogen; APOE; apolipoprotein E; APP; amyloid beta (A4) precursor protein; AR; androgen receptor; CADASIL; cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy; CST
Keywords: EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ERK; extracellular-signal-regulated kinases; ESC; embryonic stem cells; FACS; fluorescence-activated cell sorter; FGF2; fibroblast growth factor-2 (basic); IGF1; insulin-like growth fac
Keywords: Preeclampsia; IUGR; Glycosylation; Placental membrane; DSA-FACE; IR; IGF1R
Keywords: N-glycosylation; Placenta; Gestation; IR; IGF1R; IGF2R
Medaka igf1 identifies somatic cells and meiotic germ cells of both sexes
Keywords: aa; amino acid residues; igf; insulin-like growth factor; ISH; in situ hybridization; FISH; fluorescence ISH; nt; nucleotide; PGCs; primordial germ cells; cyp19a; P450 aromatase; egfr; epidermal growth factor receptor; cAMP; cyclic adenosine monophosphate
Suppression of cleavage factor Im 25 promotes the proliferation of lung cancer cells through alternative polyadenylation
Keywords: Alternative polyadenylation; Cancer; A549; IGF1R; CyclinD1; GSK3β; Proliferation; Apoptosis; P53;
Fecundity in an infertile man with r(15) - a challenge to the current paradigm
Keywords: IGF1R; Infertility; PCSK6; Ring chromosome 15; SNRPA1; TM2D3;
Bisphenol A (BPA) the mighty and the mutagenic
Keywords: GC-MS; gas chromatography-mass spectrometry; HPLC; high-performance liquid chromatography; ELISA; enzyme linked immunosorbent assay; MS; mass spectrometry; LLE; liquid/liquid extraction; SPE; solid phase extraction; DES; diethyl stilbesterol; SPCA1; s
Trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine induces lipid peroxidation-associated apoptosis via the intrinsic and extrinsic apoptosis pathways in a first-trimester placental cell line
Keywords: S-(1,2-dichlorovinyl)-l-cysteine [DCVC]; Trichloroethylene [TCE]; Apoptosis; Lipid peroxidation; Extravillous trophoblasts; Placenta; BAK1; BCL2-antagonist/killer 1; BAX; BCL2-associated X protein; BCL-2; B-cell CLL/lymphoma 2; BCL2A1; BCL2-related protei
Effect of glycated insulin on the blood-brain barrier permeability: An in vitro study
Keywords: Type 2 diabetes; Glycated insulin; AGE products; Permeability; Blood-brain barrier; BBB; blood-brain barrier; CNS; central nervous system; AGE; advanced glycated end product; HUVEC; human umbilical vein endothelial cells; T2DM; type 2 diabetes mellitus;
Oncogenic non-coding RNA NEAT1 promotes the prostate cancer cell growth through the SRC3/IGF1R/AKT pathway
Keywords: NEAT1; SRC3; Prostate cancer; IGF1R;
Understanding the mechanism of bias signaling of the insulin-like growth factor 1 receptor: Effects of LL37 and HASF
Keywords: HASF; hypoxia and Akt induced stem cell factor; Biased agonism; LL37; HASF; Extracellular-signal-regulated kinase (ERK); Insulin-like growth factor (IGF); IGF1R;
Nuclear translocation of IGF1R by intracellular amphiregulin contributes to the resistance of lung tumour cells to EGFR-TKI
Keywords: IGF1R; Nuclear trafficking; EGFR-TKI; Resistance; Lung cancer;
Nellore bulls (Bos taurus indicus) with high residual feed intake have increased the expression of genes involved in oxidative phosphorylation in rumen epithelium
Keywords: 18S; 18S ribosomal RNA; ADG; average daily gain; AQP3, AQP7, AQP8, AQP10; aquaporins 3, 7, 8, and 10; ATP1B1, ATP1B2, ATP1B3; ATPase Na+/K+ transporting subunits beta 1, 2, and 3; ATP5H; ATP synthase; BDH1, BDH2; 3-hydroxybutyrate dehydrogenase 1 and 2; B
PI3K pathway in prostate cancer: All resistant roads lead to PI3K
Keywords: CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P
Identification of a unique loss-of-function mutation in IGF1R and a crosstalk between IGF1R and Wnt/β-catenin signaling pathways
Keywords: PI3K/Akt; Wnt/β-catenin signaling; IGF1R; Receptor Tyrosine Kinases;
Mini reviewCrosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1
Keywords: CHO; Chinese hamster ovary; CSC; cancer stem cells; ECM; extracellular matrix; IGF1R; insulin-like growth factor type I receptor; IGF1; insulin-like growth factor-1; polyHEMA; poly-2-hydroxyethyl methacrylate; IGF1; Integrin; Crosstalk; Dominant-negative
Regulation of body growth by microRNAs
Keywords: miRNA; Body growth; Body size; Growth plate; Cartilage; miRNAs; microRNAs; Pri-miRNAs; primary miRNAs; GH; growth hormone; GHR; growth hormone receptor; IGF-I; insulin-like growth factor-I; IGF1R; insulin-like growth factor-I receptor; RISC; RNA-induced s
APBB1 reinforces cancer stem cell and epithelial-to-mesenchymal transition by regulating the IGF1R signaling pathway in non-small-cell lung cancer cells
Keywords: ALDH1; APBB1; Cancer stem cell; EMT; IGF1R;
Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor
Keywords: Everolimus; Platycodin D; Hsp90; Cdc37; EGFR; IGF1R;
ReviewThe IGF axis in HPV associated cancers
Keywords: HPV; IGF-I; IGF-II; IGF1R; IGF2R; Cancer;
Original ArticleSimultaneous inhibition of IGF1R and EGFR enhances the efficacy of standard treatment for colorectal cancer by the impairment of DNA repair and the induction of cell death
Keywords: IGF1R; EGFR; Radiochemotherapy; DNA damage; Apoptosis; Heterodimerisation;
Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1 Receptor-Rac1 Activation to Inhibit Keratinocyte Motility
Keywords: AS; antisense oligonucleotide; GCS; glucosylceramide synthase; GCSI; glucosylceramide synthase inhibitor; GM3S; ganglioside GM3 synthase; IGF-1; insulin-like growth factor-1; IGF1R; insulin-like growth factor-1 receptor; IR; insulin receptor; M2D3; GM2/GD
Association of rs1319868, rs1567811 and rs8041224 of IGF1R gene with infection among sickle cell anemia Tunisian patients
Keywords: IGF1R; SCA; Infection;
miR-139 is up-regulated in osteoarthritis and inhibits chondrocyte proliferation and migration possibly via suppressing EIF4G2 and IGF1R
Keywords: Osteoarthritis; miR-139; Cell proliferation and migration; EIF4G2; IGF1R;
Growth Retardation, Loss of Desmosomal Adhesion, and Impaired Tight Junction Function Identify a Unique Role of Plakophilin 1 In Vivo
Keywords: AJ; adherens junction; DSC; desmocollin; DSG; desmoglein; DSP; desmoplakin; EDSFS; ectodermal dysplasia-skin fragility syndrome; IGF1R; IGF1 receptor; KO; knockout; PG; plakoglobin; PKP; plakophilin; TJ; tight junctions; WT; wild-type;
Glucose metabolism and hepatic Igf1 DNA methylation are altered in the offspring of dams fed a low-salt diet during pregnancy
Keywords: ANOVA; analysis of variance; AUC; area under the curve; CpG; dinucleotide cytosine-guanine; GTT; glucose tolerance test; HOMA-IR; homeostatic model assessment - insulin resistance; Igf1; insulin-like growth factor 1; Igf1r; type 1 insulin-like growth fact
IGF1R and c-met as therapeutic targets for colorectal cancer
Keywords: Colorectal cancer; IGF1R; c-Met; Receptor tyrosine kinase
Molecular mechanisms of LL-37-induced receptor activation: An overview
Keywords: AMP; antimicrobial peptide; APD; antimicrobial peptide database; IFN; interferon; DC; dendritic cell; NK-cells; natural killer cells; GPCR; G protein-coupled receptor; RTK; receptor tyrosine kinase; LGIC; ligand-gated ion channel; TLR; toll-like receptor;
MiR-18b suppresses high-glucose-induced proliferation in HRECs by targeting IGF-1/IGF1R signaling pathways
Keywords: DR; diabetic retinopathy; PDR; proliferative diabetic retinopathy; HRECs; human retinal endothelial cells; REC; retinal microvascular endothelial cell; VEGF; vascular endothelial growth factor; IGF-1; insulin growth factor-1; IGF1R; insulin growth factor-
Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain
Keywords: 4-PBA; 4-phenyl butyric acid; 6-OHDA; 6-hydroxydopamine; Aβ; amyloid beta; AD; Alzheimer's disease; ATF3; activating transcription factor 3; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BACE1; β-site APP cleaving enz
miR-322 regulates insulin signaling pathway and protects against metabolic syndrome-induced cardiac dysfunction in mice
Keywords: miR; microRNA; HFD; high fat diet; CD; control diet; IGF-1; insulin growth factor-1; IGF1R; insulin growth factor-1 receptor; INSR; insulin receptor; SIRT4; sirtuin 4; CD1; cyclin D1; VSMC; vascular smooth muscle cell; FS; fractional shortening; LVESD; le
IGF2 Is Up-regulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and Is an Actionable Oncogene Product in Experimental Models
Keywords: Hepatocarcinogenesis; IGF 1 Receptor; Epi-Driver; Therapeutic Target; FC; fold change; GEMM; genetically engineered mouse model; HCC; hepatocellular carcinoma; IGF; insulin-like growth factor; IGF1R; insulin-growth factor 1 receptor; INSR; insulin recepto
Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation
Keywords: BRAF; v-Raf murine sarcoma viral oncogene homolog B; MAPK; mitogen-activated protein kinases; MMP; matrix metalloproteinase; ECM; extracellular matrix; IL-8; interleukin 8; EGFR; epidermal growth factor receptor; TIMP-2; metallopeptidase-2 or tissue inhib
Knockdown of type I insulin-like growth factor receptor inhibits human colorectal cancer cell growth and downstream PI3K/Akt, WNT/β-catenin signal pathways
Keywords: IGF1R; Cell cycle arrest; Apoptosis; Inflammation; PI3K/Akt; WNT/β-catenin