Keywords: Isoniazid resistance; Mycobacterium tuberculosis; katG; inhA; Mutation; Promotor region;
مقالات ISI (ترجمه نشده)
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Keywords: Antitubercular activity; Diphenyl ether; Enzyme inhibition; InhA; Structure-activity relationship; Triclosan;
Keywords: 11KT; 11-ketotestosterone; 17bhsd; 17β-hydroxysteroid dehydrogenase; 17P; 17α-hydroxyprogesterone; 17,20bP; 17,20β-dihydroxy-4-pregnen-3-one; 20b-HSD; 20β-hydroxysteroid dehydrogenase; 20βS; 17,20β,21-trihydroxy-4-pregnen-3-one; actRIIB; activin rec
Keywords: Antimycobacterial; Alkynoic; InhA; Sulfur
Keywords: InhA; Triclosan; GRD; DFT; QSAR; Molecular dynamics; ADMET;
Keywords: MDRTB; Nanodiagnostics; Gold nanoparticles; Tuberculosis; inhA; rpoB;
Keywords: Isoniazid; KatG; InhA; Drug resistance; Mutation
Keywords: Premature ovarian failure; BMP15; ESR1; FMR1; FSHR; INHA;
Keywords: Antitubercular activity; Isoniazid derivatives; Mycobacterium tuberculosis; Resistance; QSARs; Synthesis; AE; average error; AAE; absolute average error; ASNNs; associative neural networks; BCG; Bacillus Calmette-Guérin; CCC; concordance correlation co
Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides
Keywords: Cyclodepsipeptides; Antimycobacterial agent; PknB; InhA; Tuberculosis;
An overview on crystal structures of InhA protein: Apo-form, in complex with its natural ligands and inhibitors
Keywords: InhA; Anti-tubercular agents; Enoyl-ACP-Reductase; Molecular mechanism; Crystallographic structures; Inhibitors; Drug design;
Pharmacophore mapping, molecular docking, chemical synthesis of some novel pyrrolyl benzamide derivatives and evaluation of their inhibitory activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis
Keywords: Pyrroles; Tuberculosis; Enoyl-ACP reductase; InhA; GALAHAD;
Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor
Keywords: Tuberculosis; Antibiotic; InhA; Bactericidal; Drug discovery; Single-cell imaging; Catalase
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis
Keywords: Mycobacterium tuberculosis; InhA; Synthesis; Inhibition; Pyrrolidinone; Pyrrolidine;
New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold
Keywords: Inhibitors; InhA; Tuberculosis; Synthesis;
Detection of novel and reported mutations in the rpoB, katG and inhA genes in multidrug-resistant tuberculosis isolates: A hospital-based study
Keywords: Mycobacterium tuberculosis; Drug resistance; DNA sequencing; rpoB; katG; inhA;
Development of a Mycobacterium smegmatis transposon mutant array for characterising the mechanism of action of tuberculosis drugs: Findings with isoniazid and its structural analogues
Keywords: Mycobacterium; Tuberculosis; Smegmatis; Transposon; Isoniazid; nudC; inhA;
Synthesis, molecular docking and anti-mycobacterial evaluation of new imidazo[1,2-a]pyridine-2-carboxamide derivatives
Keywords: Anti-mycobacterial activity; Imidazopyridine amide; InhA; Tuberculosis; X-ray crystallographyTB, tuberculosis; MDR, multiple drug-resistant; XDR, extensively drug-resistant; HIV-AIDS, human immunodeficiency virus-acquired immunodeficiency syndrome; DIPEA,
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth
Keywords: Medicinal chemistry; Inhibitors; InhA; Mycobacterium tuberculosis; Efflux pumps;
Association of inhibin α gene promoter polymorphisms with risk of idiopathic primary ovarian insufficiency in Korean women
Keywords: Idiopathic primary ovarian insufficiency; POI; Inhibin alpha; INHA; Polymorphism
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis
Keywords: Succinimide; Michael addition; Tuberculosis; InhA
Stearoyl-CoA desaturase regulates inflammatory gene expression by changing DNA methylation level in 3T3 adipocytes
Keywords: SCD1; stearoyl-CoA desaturase 1; WAT; white adipose tissue; TNFα; tumor necrosis factor-α; IL6; interleukin 6; MCP1; monocyte chemoattractant protein 1; LPS; lipopolysaccharide; Il10ra; interleukin 10 receptor a; Il6st; interleukin 6 signal transducer;
Development of 2-(4-oxoquinazolin-3(4H)-yl)acetamide derivatives as novel enoyl-acyl carrier protein reductase (InhA) inhibitors for the treatment of tuberculosis
Keywords: Tuberculosis; Enoyl acyl carrier protein reductase; InhA; Cytotoxicity
Development of benzo[d]oxazol-2(3H)-ones derivatives as novel inhibitors of Mycobacterium tuberculosis InhA
Keywords: Tuberculosis; InhA; Enoyl acyl carrier protein reductase; Cytotoxicity;
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis
Keywords: Mycobacterium tuberculosis; InhA; Inhibition; 3-(9H-Fluoren-9-yl)pyrrolidine-2,5-dione; Succinimide;
Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents
Keywords: Inhibitor; Triazole; Enoyl ACP reductase; InhA; Tuberculosis
Gene-environment interactions: The potential role of contaminants in somatic growth and the development of the reproductive system of the American alligator
Keywords: Alligator; Ovary; Aromatase; Activin; Follistatin; Growth; CYP11A1; cytochrome P450, family 11, subfamily A, polypeptide 1 (side chain cleavage); CYP17A1; cytochrome P450, family 17, subfamily A, polypeptide 1 (17-alpha-hydroxylase); CYP19A1; cytochrome P
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents
Keywords: Inhibitor; Triazole; Enoyl ACP reductase; InhA; Tuberculosis;
A pyrosequencing method for molecular monitoring of regions in the inhA, ahpC and rpoB genes of Mycobacterium tuberculosis
Keywords: AhpC; inhA; Mycobacterium tuberculosis; pyrosequencing, rpoB
Isoniazid-resistant tuberculosis in Denmark: Mutations, transmission and treatment outcome
Keywords: Resistance; Therapy; Restriction fragment length polymorphism; katG; inhA; rpoB
Investigating the structural basis of arylamides to improve potency against M. tuberculosis strain through molecular dynamics simulations
Keywords: Molecular dynamics simulations; Arylamide; InhA; M. tuberculosis
Molecular characterization of INH-resistant Mycobacterium tuberculosis isolates by PCR-RFLP and multiplex-PCR in North India
Keywords: Tuberculosis; INH; PCR-RFLP; Multiplex-PCR; katG; inhA
The clinical relevance of Mycobacterial pharmacogenetics
Keywords: Mycobacterium tuberculosis; inhA; Isoniazid; High dose
Discovery of potential new InhA direct inhibitors based on pharmacophoreand 3D-QSAR analysis followed by in silico screening
Keywords: InhA; Pyrrolidine carboxamide; Pharmacophore; 3D-QSAR; Virtual screening; Docking
Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors
Keywords: Tuberculosis; Diaryl ether; Enoyl reductase; Mycolic acids; InhA; Isoniazid; Antitubercular drug; Diphenyl ether; FabI; Lipinski parameter; Bioavailability
Combined effect of epigallocatechin gallate and triclosan on enoyl-ACP reductase of Mycobacterium tuberculosis
Keywords: Mycobacterium tuberculosis; Tuberculosis; InhA; Enoyl reductase; FAS I; FAS II; Tea catechins; Epigallocatechin gallate; EGCG; Triclosan; Fluorescence titration; Scatchard plot;
Evaluation of N-(phenylmethyl)-4-[5-(phenylmethyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-4-yl]benzamide inhibitors of Mycobacterium tuberculosis growth
Keywords: Mycobacterium tuberculosis; Imidazopiperidines; InhA
Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis
Keywords: Mycobacterium tuberculosis; InhA; Crystal structure; Isoniazid; Drug resistance; Enoyl-ACP reductase
Evaluation of the CombiChip Mycobacteria™ Drug-Resistance detection DNA chip for identifying mutations associated with resistance to isoniazid and rifampin in Mycobacterium tuberculosis
Keywords: Oligonucleotide microchip; Isoniazid; Rifampin; M. tuberculosis; katG 315; inhA; rpoB