Keywords: Oral squamous cell carcinoma; Head and neck cancer; Tongue cancer; OPLS-DA; Tissue proteomics; CA1; S100A7; Neutrophil defensin 1; ANP32B; Immunohistochemistry; ALYREF; THO complex subunit 4; ANP32B; Acidic leucine-rich nuclear phosphoprotein 32 family me
مقالات ISI (ترجمه نشده)
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Keywords: Resistin-like molecule; Macrophage; Helminth infection; T helper type 2; Toll-like Receptor 4; ABC; ATP-binding cassette transporter; ADD1; adipocyte determination and differentiation dependent factor 1; ADSF; adipocyte secreted factor; Akt (aka PKB); pro
Keywords: α-CGRP; alpha-calcitonin gene related peptide; Ang; angiopoietin; AE2; anion exchanger 2; ADP; adenosine diphosphate; ADPKD; autosomal dominant polycystic kidney disease; ATP; adenosine triphosphate; ASBT; sodium-dependent bile acid transporter; AQP; aqu
Keywords: AFM; (mixed) amplitude and frequency modulation; AM; amplitude modulation; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATP; adenosine triphosphate; BC; basket cell; ER; endoplasmic reticulum; FM; frequency modulation; GABA; γ-aminobutyri
Keywords: AANAT; arylalkylamine N-acetyltransferase; AE2; Clâ/HCO3- anion exchanger 2; ANIT; α-naphthylisothiocyanate; BA; biliary atresia; BDL; bile duct ligation; cAMP; adenosine 3â²,5â²-cyclic monophosphate; CCA; cholangiocarcinoma; CCl4; carbon tetrachlo
Keywords: Ca2+; Endoplasmic reticulum; Lysosome; Synaptic plasticity; Alzheimer's disease; SOCE; RyR; IP3R;
Keywords: ADP; adenosine diphosphate; AMP; adenosine monophosphate; ATP; adenosine triphosphate; [Ca2+]i; intracellular calcium concentration; CaM; calmodulin; CaMKII; Ca2+/calmodulin-dependent kinase II; cAMP; cyclic adenosine monophosphate; COX-2; cyclooxygenase-
Keywords: ATP; adenosine triphosphate; Ca2+; Â calcium; CamK; calmodulin-dependent kinase; ChREBP; carbohydrate response element binding protein; CypD; cylophilin D; DGAT2; diacylglycerol acyltransferase 2; ER; endoplasmic reticulum; FOXO1; Forkhead box O1; G6P; gl
Keywords: CM; cardiomyocyte; Fab; the Fab fragment of the monoclonal anti-PLB antibody 2D12; IP3R; inositol 1,4,5-trisphosphate receptor; nCa2Â +; Â perinuclear/nuclear Ca2Â +; Â NE; nuclear envelope; NM; perinuclear/nuclear membranes; PLB; phospholamban; RyR2; rya
Keywords: 5-HT; Serotonin; BMI; Body Mass Index; CBT; Cognitive Behavioural Therapy; CEE; Conjugated Equine Estrogen; CES-D; Centre for Epidemiological Studies of Depression scale; CI; Confidence Interval; CVD; Cardiovascular Disease; DSM-IV; Diagnostic and Statist
Keywords: ÎΨm; mitochondrial transmembrane potential; CAD; caspase-activated DNase; CaM; calmodulin; CaMKII; Ca2 +/calmodulin-dependent protein kinase II; CypD; cyclophilin D; DISC; death-inducing signalling complex; FADD; Fas-associated protein with death domai
Keywords: 2-APB; 2-aminoethoxydiphenyl borate; BAPTA-AM; 1,2-bis(2-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid acetoxymethyl ester; BCA; bicinchonininc acid; CFM; calcium-free medium; ECL; enhanced chemiluminescence; ER; endoplasmic reticulum; IP3; inositol
Keywords: EDL; extensor digitorum longus; ER; endoplasmic reticulum; ERAD; endoplasmic reticulum-associated degradation; DHPR; dihydropyridine receptor; HHATL; hedgehog acyltransferase-like; IP3R; inositol trisphosphate receptor; JP; junctophilin; LC-MS/MS; liqui
Keywords: RyR; ryanodine receptor; [Ca2+]i; intracellular Ca2+ concentration; IP3R; inositol trisphosphate receptor; ER; endoplasmic reticulum; TC; terminal cisternae; LSR; longitudinal sarcoplasmic reticulum; CICR; Ca2+ induced Ca2+ release; SERCA; sarco-endoplasm
Keywords: Insulin; Ca2+; Cardiomyocytes; Myotubes; IP3R; RyR; GLUT4; NOX2; Mitochondria
Keywords: BK; big potassium channel; BN-PAGE; blue native polyacrylamide gel electrophoresis; Cav; voltage-gated calcium; CNG; cyclic nucleotide-gated channels; CRAC; cholesterol binding sites; CTD; cytoplasmic domain; ENaC; epithelial sodium channels; FRET; Först
Keywords: CaMKII; Ca2Â +/calmodulin dependent protein kinase II; cAMP; cyclic adenosine monophosphate; cTn; cardiac Troponin; DAD; delayed afterdepolarization; EAD; early afterdepolarization; ECC; excitation-contraction coupling; H2O2; hydrogen peroxide; HNO; Nit
Keywords: Diabetes; Cancer; Insulin; Anti-diabetics; Cannabinoid; Obesity; 2-AG; 2-arachidonoyl glycerol; ACC; acetyl-CoA carboxylase; AMPK; adenosine monophosphate-activated protein kinase; CB1R; cannabinoid 1 receptor; CB2R; cannabinoid 2 receptor; CPT-1; carniti
Keywords: AGES; advanced glycation end products; BI-1; Bax inhibitor-1; CPA; cyclopiazonic acid; CICR; calcium-induced calcium release; EC; endothelial cell; eNOS; endothelial nitric oxide synthase; ER; endoplasmic reticulum; IP3R; inositol 1,4,5-trisphosphate rece
Keywords: Ryanodine receptor; IP3R; ER; Neuron; Brain; Neurodegeneration; Calcium; Alzheimer's disease; Synaptic plasticity; Amyloid; Clinical trials
Keywords: Ï-CTX; Ï-conotoxin GVIA; BIM; BIM 23056; CYN; CYN-154806; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; EGTA; ethylene glycol-bis(β-aminoethyl ether) N,N,Nâ²,Nâ²-tetraacetic acid; GABA; γ-aminobutyric acid; HEPES; 4-(2-hydr
The role of TRPV4 in fibrosis
Keywords: α-SMA; α-smooth muscle actin; aa; amino acids; AHF; alcohol/high fat diet; AIP4; atrophin-interacting protein 4; ANK; ankyrin; ARS-L; arachidonate-like recognition sequence; ASL; airway surface liquid; BKCa; Ca2 +-dependent K+; [Ca2 +]i; intracellular
A critical appraisal of the role of intracellular Ca2+-signaling pathways in Kawasaki disease
Keywords: [Ca2+]cyt; free cytosolic Ca2+ concentration; CRAC; Ca2+-release activated Ca2+ entry; EBV; Epstein-Barr virus; ER; endoplasmic reticulum; IP3; inositol 1,4,5-trisphosphate; IP4; inositol 1,3,4,5-tetrakisphosphate; IP3R; IP3 receptor; KD; Kawasaki disease
Ripk3 regulates cardiac microvascular reperfusion injury: The role of IP3R-dependent calcium overload, XO-mediated oxidative stress and F-action/filopodia-based cellular migration
Keywords: Calcium overload; ER; IP3R; IR injury; Microcirculation; Oxidative stress; Ripk3; XO;
Selective inhibition of histamine-evoked Ca2+ signals by compartmentalized cAMP in human bronchial airway smooth muscle cells
Keywords: AC; adenylyl cyclase; 2-APB; 2-aminoethoxyphenylborane; ASM; airway smooth muscle; cAMP; 3',5'-cyclic AMP; COPD; chronic obstructive pulmonary disease; [Ca2+]i; intracellular free Ca2+ concentration; DMSO; dimethyl sulfoxide; EC50 (IC50); half-maximally e
Phospholamban regulates nuclear Ca2+ stores and inositol 1,4,5-trisphosphate mediated nuclear Ca2+ cycling in cardiomyocytes
Keywords: Phospholamban; Calcium signaling; Cardiomyocyte; Nuclear membranes; 1,4,5-Trisphosphate receptor; Sarcoplasmic reticulum Ca2+ cycling; Nuclear Ca2+ dynamics; CM; cardiomyocyte; ER; endoplasmic reticulum; Fab; the Fab fragment of the monoclonal anti-PLB an
The effects of mitochondrial inhibitors on Ca2+ signalling and electrical conductances required for pacemaking in interstitial cells of Cajal in the mouse small intestine
Keywords: CTC; Ca2+ transient cluster; ETC; electron transport chain; FOV; field of view; GI; gastrointestinal; ICC; interstitial cells of Cajal; ICC-DMP; interstitial cells of Cajal at the level of the deep muscular plexus; ICC-IM; intramuscular interstitial cells
Peptide YY (3-36) modulates intracellular calcium through activation of the phosphatidylinositol pathway in hippocampal neurons
Keywords: PYY; peptide YY; NPY; neuropeptide Y; PP; pancreatic polypeptide; Y2R; Y2 receptor; CNS; central nervous system; Ca2Â +; Â calcium; [Ca2Â +]i; intracellular Ca2Â + concentrations; HBS; HEPES-buffered solution; GPCR; G-protein coupled receptors; ER; endopl
Pathophysiological consequences of isoform-specific IP3 receptor mutations
Keywords: ALS; amyotrophic lateral sclerosis; Bcl-2; B-cell lymphoma-2; CA8; carbonic anhydrase 8 (carbonic anhydrase-related protein); CSCC; cervical squamous cell carcinoma; CTT; C-terminal tail; DKO; double knockout; FAD; familial Alzheimer's disease; GS; Gilles
Mitochondria-associated membranes (MAMs): An emerging platform connecting energy and immune sensing to metabolic flexibility
Keywords: Organelle communication; Mitochondria-associated membranes; Nutrients; Microbiome; Innate immunity; Insulin sensitivity; Metabolic diseases; Ca2+; calcium; CLRs; C-type lectin receptors; CypD; cyclophilin D; DAMPs; Danger-Associated Molecular patterns; ER
IP3R3 silencing induced actin cytoskeletal reorganization through ARHGAP18/RhoA/mDia1/FAK pathway in breast cancer cell lines
Keywords: IP3R; inositol 1,4,5-trisphosphate receptors; FAK; Focal Adhesion Kinase; GAP; Rho GTPases activating proteins; Breast cancer; Type 3 inositol 1,4,5-trisphosphate receptor; Cytoskeleton; Actin; Rho GTPases; Calcium;
Herpud1 impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca2+-calcineurin-Akt axis
Keywords: AdLacZ; adenovirus encoding β-galactosidase; CAIN; calcineurin inhibitor; CA-CN; constitutively-active calcineurin; CsA; cyclosporine A; [3H]-2DG; [3H]2-deoxyglucose; ER; endoplasmic reticulum; KO; knockout; Herpud1; homocysteine-inducible endoplasmic re
Amyloid toxicity is enhanced after pharmacological or genetic invalidation of the Ï1 receptor
Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; Aβ25-35; amyloid-β[25-35] peptide; BDNF; brain-derived neurotrophic factor; BiP; 78 kDa glucose-regulated protein; cAMP; cyclic adenosine monophosphate; CREB;
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury
Keywords: 2-APB; 2-aminoethoxydiphenyl borate; AD; Alzheimer's disease; ATF6; activating transcription factor 6; BiP; binding immunoglobulin protein; BSA; bovine serum albumin; CHOP; CCAAT enhancer binding protein homologous protein; DRG; dorsal root ganglion; ED
The activation of STIM1 mediates S-phase arrest and cell death in paraquat induced acute lung intoxication
Keywords: ALI; acute lung injury; 2-APB; 2-Aminoethoxydiphenyl borate; BSA; bovine serum albumin; CCNA/CCND/Cyclin A/D; mammalian A/D-type Cyclin; CDK; Cyclin dependent kinase; CKI; Cyclin dependent kinase inhibitor; CRISPR-CAS9; clustered regularly interspaced sho
Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor-transmembrane protein 16A-voltage-dependent Ca2+ channel axis and contribute to bronchial hyperresponsiveness in asthma
Keywords: Airway smooth muscle; asthma; hypersensitivity; inflammatory mediator; TMEM16A; 5-HT; 5-Hydroxytryptamin; Ai38D; Cre-dependent GCaMP3 reporter mouse; ASM; Airway smooth muscle; ASMC; Airway smooth muscle cell; ClCa; Ca2+-activated Clâ; CTR; Control; GCa
Autophagy in ischemic stroke
Keywords: 3-MA; 3-methyladenine; Aβ; amyloid β; AIF; apoptosis-inducing factor; Akt; protein kinase B; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; Atg; autophagy-related genes; ATP; adenosine 5â²-triphosphate; BBB; blood-brain ba
Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension
Keywords: ADRF; adipocyte-derived relaxing factor; AE; anion exchanger; ATP; adenosine triphosphate; BH4; tetrahydrobiopterin; BKCa; big conductance Ca2+-sensitive K+ channel; CaM; calmodulin; cAMP; cyclic adenosine monophosphate; CAT; cysteine aminotransferase; CB
BAPTA-AM decreases cellular pH, inhibits acidocalcisome acidification and autophagy in amino acid-starved T. brucei
Keywords: Acidocalcisome acidification; Autophagy; BAPTA-AM; Calcium; IP3R; SERCA;
Regulation of IP3 receptors by cyclic AMP
Keywords: AC; adenylyl cyclase; EPAC; exchange protein activated by cAMP; IP3; inositol 1,4,5-trisphosphate; IP3R; IP3 receptor; IRAG; IP3R-associated cGMP kinase substrate; IRBIT; IP3R-binding protein released by IP3; PKA; protein kinase A (cAMP-dependent protein
Acetylcholine-induced ex vivo ATP release from the human nasal mucosa
Keywords: Ach; acetylcholine; M3AchR; M3 acetylcholine receptor; PLC; phospholipase C; PIP2; phosphatidylinositol bisphosphate; DAG; diacylglycerol; IP3; inositol triphosphate; IP3R; inositol triphosphate receptor; P2X7; purinergic P2X7 receptor; Human nasal mucosa
Distinct phosphodiesterase 5A-containing compartments allow selective regulation of cGMP-dependent signalling in human arterial smooth muscle cells
Keywords: HASMC; human arterial smooth muscle cell; cAMP; 3â²5â², cyclic adenosine monophosphate; cGMP; 3â²5â², cyclic guanosine monophosphate; PDE; cyclic nucleotide phosphodiesterase; PKA; protein kinase A; PKG; protein kinase G; IP3; inositol-1, 4, 5-trispho
Mag-Fluo4 in T cells: Imaging of intra-organelle free Ca2Â + concentrations
Keywords: AM; acetoxymethylester; [Ca2Â +]ER; free luminal endoplasmic reticular Ca2Â + concentration; [Ca2Â +]i; free cytosolic Ca2Â + concentration; [Ca2Â +]mito; free luminal mitochondrial Ca2Â + concentration; cADPR; cyclic adenosine diphosphoribose; ER; endopl
Resveratrol-induced autophagy is dependent on IP3Rs and on cytosolic Ca2Â +
Keywords: Akt; protein kinase B; AMPK; AMP-activated protein kinase; BAPTA-AM; 1,2-bis(o-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid acetoxymethyl ester; DMEM; Dulbecco's modified Eagle's medium; EGTA; ethylene glycol tetraacetic acid; ER; endoplasmic reticu
Orai3 channel is the 2-APB-induced endoplasmic reticulum calcium leak
Keywords: 2-APB; 2-aminoethoxydiphenyl borate; Ca2+; calcium; [Ca2+]ER; Endoplasmic Reticulum Ca2+concentration; [Ca2+]i; intracellular Ca2+concentration; IP3; Inositol 1,4,5- trisphosphate; IP3R; inositol 1,4,5-trisphosphate receptor; SERCA; sarco/endoplasmic reti
DPB162-AE, an inhibitor of store-operated Ca2+ entry, can deplete the endoplasmic reticulum Ca2+ store
Keywords: 2-APB; 2-aminoethyl diphenylborinate; AUC; area under the curve; [Ca2+]cyt; cytosolic calcium concentration; CPA; cyclopiazonic acid; ER; endoplasmic reticulum; HEK293wt; HEK293 wild-type cells; HEK 3KO; HEK triple IP3R-knockout cells; IP3R; inositol 1,4,
Activation of endoplasmic reticulum calcium leak by 2-APB depends on the luminal calcium concentration
Keywords: 2-APB; 2-aminoethoxydiphenyl borate; Ca2+; calcium; [Ca2+]; ERendoplasmic reticulum Ca2+ concentration; [Ca2+]i; intracellular Ca2+ concentration; IP3; Inositol 1,4,5- trisphosphate; IP3R; inositol 1,4,5-trisphosphate receptor; SERCA; sarco/endoplasmic re
Shear stress enhances Ca2Â + sparks through Nox2-dependent mitochondrial reactive oxygen species generation in rat ventricular myocytes
Keywords: CCCP; carbonyl cyanide 3-chlorophenylhydrazone; DPI; diphenyleneiodonium; DTT; dl-dithiothreitol; ICa; L-type Ca2Â + current; IP3R; inositol 1,4,5-trisphosphate receptor; L-NAME; NG-nitro-L-arginin methyl ester; NCX; Na+-Ca2Â + exchanger; NOS; nitric oxid
Activation of phospholipase C-γ1 and translocation of phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase contribute to GL-V9-induced apoptosis in human gastric cancer cells
Keywords: PLCγ1; phospholipase C-γ1; PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase; CHOP; CCAAT/enhancer-binding protein-homologous protein; ER; endoplasmic reticulum; ROS; reactive oxygen species; IP3; inositol1,4,5-trisphosphate; IP3R; inositol1,