Keywords: Atherosclerosis; Cardiovascular diseases; Cell cycle; Proliferation; Pulmonary hypertension; Restenosis; Signaling pathway; Vascular smooth muscle cells; ACE; angiotensin converting enzyme; aFGF; acidic FGF; Ang II; angiotensin II; AP-1; activating protei
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Keywords: AF; atrial fibrillation; ApoE; apolipoprotein E; CD36; cluster of differentiation 36; DHE; dihydroethidium; ESTs; expressed sequence tag; IPA; Ingenuity Pathway Analysis; IP3R1; inositol 1,4,5-trisphosphate receptor type 1; LA; left atrium; P2RY12; purine
Keywords: ATF4; activating transcription factor-4; ATF6α; activating transcription factor-6α; EB1; end binding protein-1; EDEM; ER degradation-enhancing α-like protein; ER; endoplasmic reticulum; ERAD; ER-associated degradation; GCN2; general control non-derepre
Promoter analysis and transcriptional regulation of human carbonic anhydrase VIII gene in a MERRF disease cell model
Keywords: Gene transcription; Promoter; Specificity protein 1 (Sp1); Myoclonus epilepsy with ragged-red fibers (MERRF); Human carbonic anhydrase VIII (CA8); AP-2; activator protein-2; CA8; carbonic anhydrase 8; CARPs; CA-related proteins; DNA; deoxyribonucleic acid
Identification of novel regulatory GRE-binding elements in the porcine IP3R1 gene promoter and their transcriptional activation under glucocorticoid stimulation
Keywords: IP3R1; inositol 1, 4, 5-trisphosphate receptor 1; DEX; dexamethasone; GCs; glucocorticoids; GRα; glucocorticoids receptor α; GRE; glucocorticoids receptor element; HPA; hypothalamic-pituitary-adrenal axis; PSE; pale, soft and exudative; ACTD; actino
Disruption of dopamine D1/D2 receptor complex is involved in the function of haloperidol in cardiac H9c2 cells
Keywords: cAMP; 3â²5â²-cyclic adenosine monophosphate; D1R; dopamine D1 receptor; D2R; dopamine D2 receptor; DBP; diastolic blood pressure; Hal; haloperidol; HR; heart rate; IP3; inositol 1,4,5-trisphosphate; IP3R1; IP3 receptor type 1; Me; melperone hydrochlorid
Alpha-lipoic acid attenuates endoplasmic reticulum stress-induced insulin resistance by improving mitochondrial function in HepG2 cells
Keywords: ALA; alpha-lipoic acid; ER stress; endoplasmic reticulum (ER) stress; HepG2; hepatoblastoma cell line; Tun; tunicamycin; OXPHOS; oxidative phosphorylation; Olig; oligomycin; T2DM; type 2 diabetes mellitus; IRS; insulin receptor substrate; PI3K; phosphatid
Endoplasmic reticulum Ca2+ content decrease by PKA-dependent hyperphosphorylation of type 1 IP3 receptor contributes to prostate cancer cell resistance to androgen deprivation
Keywords: IP3R1; Apoptosis; Endoplasmic reticulum; Prostate cancer; PKA; Hormone therapy;
Cyclophilin D and myocardial ischemia-reperfusion injury: A fresh perspective
Keywords: ANT; adenine nucleotide translocator; ATP; adenosine triphosphate; ATP5G; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9); BAK; BCL2-antagonist/killer; BAX; BCL2-associated X protein; BCL-2; B cell lymphoma protein 2; C1QBP
Effect of M-phase kinase phosphorylations on type 1 inositol 1,4,5-trisphosphate receptor-mediated Ca2+ responses in mouse eggs
Keywords: Mouse eggs; Calcium; IP3R1; Egg activation;
Aβ leads to Ca2+ signaling alterations and transcriptional changes in glial cells
Keywords: Glial cells; Amyloid beta; Alzheimer's disease; Calcium deregulation; mGluR5; IP3R1; Calcineurin
Redox signaling loops in the unfolded protein response
Keywords: AGR2; anterior gradient 2; ARE; antioxidant responsive element; ATF4; activating transcription factor-4; ATF6; activating transcription factor-6; ASK1; apoptosis signal-regulating kinase-1; BI-1; BAX inhibitor-1; BiP; immunoglobulin heavy chain-binding pr
RNA therapeutics targeting osteoclast-mediated excessive bone resorption
Keywords: 3BP2; c-Abl SH3 domain-binding protein-2; ADAM; a disintegrin and metalloproteinases; Ago; Argonaute; AP-1; activator protein-1; Ckb; brain-type creatine kinase; CNV; choroidal neovascularization; CPA; cation-proton antiporter; CPC; calcium phosphate bone
Induction of Ca2+ signal mediated apoptosis and alteration of IP3R1 and SERCA1 expression levels by stress hormone in differentiating C2C12 myoblasts
Keywords: DEX; Calcium; Apoptosis; IP3R1; SERCA1; GRE
Altered expression of type 1 inositol 1,4,5-trisphosphate receptor in the Ngsk Prnp deficient mice
Keywords: doppel; IP3R1; calcium; purkinje cell; NFATc4; neurodegenerationBDNF, brain-derived neurotrophic factor; CHO, Chinese Hamster Ovary; CNS, central nervous system; Dpl, Doppel; EMSA, electrophoretic mobility shift assay; ER, endoplasmic reticulum; GluR2, io
The complex regulatory function of the ligand-binding domain of the inositol 1,4,5-trisphosphate receptor
Keywords: AHCY; S-adenosyl-l-homocysteine hydrolase; CaBP; Ca2+-binding protein; CaM; calmodulin; ER; endoplasmic reticulum; EVH; Ena/VASP homology; IICR; IP3-induced Ca2+ release; IP3; inositol 1,4,5-trisphosphate receptor; IP3R1; type 1 IP3 receptor; IP3R2; type
ERK binds, phosphorylates InsP3 type 1 receptor and regulates intracellular calcium dynamics in DT40 cells
Keywords: IP3R1; ERK1/2; DT40; FRET; Phosphorylation
Inositol 1,4,5-trisphosphate receptor type 1 phosphorylation and regulation by extracellular signal-regulated kinase
Keywords: Mouse; IP3R1; ERK1/2; IP3 binding; Phosphorylation