MyD88, IRAK1 and TRAF6 knockdown in human chondrocytes inhibits interleukin-1-induced matrix metalloproteinase-13 gene expression and promoter activity by impairing MAP kinase activation
Keywords: Interleukin-1; Signal transduction; MyD88; IRAK1; TRAF6; RNA interference; Transcription factors; Matrix metalloproteinase-13; Gene regulation; Rheumatoid arthritis; Cartilage