Keywords: 3-MP; 3-mercaptopyruvate; 3-MST; 3-mercaptopyruvate sulfurtransferase; AAT; aspartate amino transferase; AE1; anion exchanger-1; AGEs; advanced glycation end products; AKI; acute kidney injury; AMPK; AMP-activated protein kinase; AT1; angiotensin receptor
مقالات ISI (ترجمه نشده)
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Keywords: Potassium channel; Placenta; Early pregnancy; KCNQ; KCNE
Keywords: Drosophila; Heart; Development; Cardiomyopathy; Optical heartbeat analysis; Electrophysiology; Atomic force microscopy; Immunohistochemistry; KCNQ; Tinman;
Keywords: BK; big potassium channel; BN-PAGE; blue native polyacrylamide gel electrophoresis; Cav; voltage-gated calcium; CNG; cyclic nucleotide-gated channels; CRAC; cholesterol binding sites; CTD; cytoplasmic domain; ENaC; epithelial sodium channels; FRET; Först
Keywords: DRG; Nociceptor; M channel; KCNQ; K2P; Ion channel; Pain;
Keywords: aCSF; artificial cerebrospinal fluid; 4-AP; 4-aminopyridine; DH; dorsal horn; SG; substantia gelatinosa; VH; ventral horn; Dorsal horn; Oscillatory activity; KCNQ; Nociception; Potassium channels; M-current;
A constitutively-active IKK-complex at the axon initial segment
Keywords: Axon initial segment; NF-κB; IKK 2 Kinase; Ankyrin-G; Proximity ligation assay; Axon; AIS; axon initial segment; ASA; acetyl-salicylic acid; DMEM; Dulbecco's modified Eagle media; eGFP; enhanced green-fluorescent protein; FADD; Fas-associated death dom
Retigabine diminishes the effects of acetylcholine, adrenaline and adrenergic agonists on the spontaneous activity of guinea pig smooth muscle strips in vitro
Keywords: KCNQ (Kv7) channels; voltage-gated potassium channels; KS; modified Krebs solution; ACh; acetylcholine; AUC; area under the curve; BT; baseline tone; BT + Amean; relative change in spontaneous muscle contraction; KCNQ; Acetylcholine; Adrenaline; α-adre
Electrophysiological characterization of the M-current in rat hypoglossal motoneurons
Keywords: ACh; acetylcholine; AP; action potential; APV; (2R)-amino-5-phosphonovaleric acid; DHβE; dihydro-β-erythroidine; DNQX; 6,7-dinitroquinoxaline-2,3-dione; EK; potassium equilibrium potential; GABA; γ-aminobutyric acid; HM; hypoglossal motoneuron; Ih; hyp
The lateral habenula and alcohol: Role of glutamate and M-type potassium channels
Keywords: AUD; alcohol use disorder; BK; big potassium; BNST; bed nucleus of the stria terminalis; CAMKII; calcium/calmodulin dependent kinase II; CeA; Central Amygdala; CTA; conditioned taste aversion; DA; dopaminergic; DAR; dopamine receptors; D1R; dopamine recep
Discovery of a novel Kv7 channel opener as a treatment for epilepsy
Keywords: Kv7 channel opener; KCNQ; PF-05020182; Dimethoxypyrimidine; Maximal electroshock; Pentylenetetrazole-induced seizure; Amygdala-kindled seizure;
Kv7 channels as targets for anti-epileptic and psychiatric drug-development
Keywords: KCNQ; Kv7; Anti-manic; Anti-psychotic; Anti-convulsion; Mode-of-action;
The KV7.2/3 preferring channel opener ICA 27243 attenuates L-DOPA-induced dyskinesia in hemiparkinsonian rats
Keywords: LID; KCNQ; ICA 27243;
Electrophysiological correlates of hyperalgesic priming in vitro and in vivo
Keywords: Action potential; Hyperalgesia; KCNQ; Nociceptor; Pain; Prostaglandin E2; Resting membrane potential; Tumor necrosis factor alpha;
Time course and duration of changes in Kv7.2 and Kv11.1 mRNA expression in the hippocampus and piriform cortex following electroconvulsive stimulations
Keywords: ECT; ECS; erg; kcnq; seizure
The genetics of monogenic idiopathic epilepsies and epileptic encephalopathies
Keywords: Monogenic; Epilepsy; Epileptic encephalopathies; Channels; SCN1A; KCNQ;
Kv7 (KCNQ) channel openers induce hypothermia in the mouse
Keywords: Kv7; KCNQ; Retigabine; ICA-27243; Hypothermia; Thermoregulation;
Drosophila as a model to study cardiac aging
Keywords: Insulin; KCNQ; Dystrophin; Heart; Senescence; Sulfonylurea receptor (SUR); Target of Rapamycin (TOR);
Identification of novel KCNQ4 openers by a high-throughput fluorescence-based thallium flux assay
Keywords: KCNQ; Kv7; Patch clamp; Stable cell line; Thallium flux; 86Rubidium flux; Potassium channel opener; High-throughput screening;
Effects of the potassium ion channel modulators BMS-204352 Maxipost and its R-enantiomer on salicylate-induced tinnitus in rats
Keywords: RM-ANOVA; repeated measures analysis of variance; SS; sodium salicylate; SIP; schedule induced polydipsia; SIPAC; Schedule Induced Polydipsia Avoidance Conditioning; SEM; standard error of the mean; Tinnitus; Salicylate; Schedule induced polydipsia; Rats;
Examining the effects of age, sex, and body mass index on normative median motor nerve excitability measurements
Keywords: Nerve excitability; Sex; QTRAC; Ageing; Peripheral nerve; BMI; KCNQ
Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury
Keywords: KCNQ; M current; REST; Sensory neuron; DRG; Neuropathic pain;
Phospholipase C-mediated inhibition of the M-potassium current by muscarinic-receptor activation in the vestibular primary-afferent neurons of the rat
Keywords: Vestibular system; Inner ear; KCNQ; XE-992; Oxotremorine-M; U73122; Second messenger; Afferent neurons; Efferent system; Hair cells
Antimanic efficacy of retigabine in a proposed mouse model of bipolar disorder
Keywords: KCNQ; Lithium; Mania; Amphetamine; Anhedonia; Depression
Functional effects of the KCNQ modulators retigabine and XE991 in the rat urinary bladder
Keywords: Bladder; Urinary incontinence; Retigabine; XE991; KCNQ; KV7; M-current
Differential modulation of cardiac potassium channels by Grb adaptor proteins
Keywords: Oocyte; Grb; Channel; Regulation; Kv7; KCNE; KCNQ; Heart; Cardiac; Interaction
The KCNQ2/3 selective channel opener ICA-27243 binds to a novel voltage-sensor domain site
Keywords: KCNQ; Kv7; K+ channel opener; ICA-27243; Retigabine; Binding site; Voltage-sensor domain; Sub-type-selective
Opposite regulation of KCNQ5 and TRPC6 channels contributes to vasopressin-stimulated calcium spiking responses in A7r5 vascular smooth muscle cells
Keywords: Vasopressin; Calcium spiking; KCNQ; TRPC6; Resting membrane potential
The muscarinic inhibition of the potassium M-current modulates the action-potential discharge in the vestibular primary-afferent neurons of the rat
Keywords: efferent synapse; KCNQ; linopirdine; XE-991; E4031; muscarinic receptorsAChE, acetylcholinesterase; AHP, afterhyperpolarization; E-4031, N-[4-[[1-[2-(6-methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamide dihydrochloride; IK(erg), er
Skeletal muscle Kv7 (KCNQ) channels in myoblast differentiation and proliferation
Keywords: KCNQ; Skeletal muscle; Proliferation; Myogenesis; Potassium channels
Effect of the new antiepileptic drug retigabine in a rodent model of mania
Keywords: KCNQ; Kv7; Retigabine; Lithium; Lamotrigine; Mania; Bipolar disorder; Rat; Animal model
Drosophila aging 2006/2007
Keywords: Endocrine systems; Senescence; Insulin; TOR; KCNQ; Dietary restriction; Sleep; Circadian rhythm; Cardiac aging; Arrhythmia; Heart failure; Heart disease
Expression profile and characterisation of a truncated KCNQ5 splice variant
Keywords: KCNQ; Splice variant; Smooth muscle; Kv7
Retigabine reduces the excitability of unmyelinated peripheral human axons
Keywords: Neuronal potassium channel activator; Retigabine; KCNQ; M channel; Kv7; Axonal excitability; Human C-fiber; Electrophysiology; Threshold tracking; Neuropathic pain; Nociception
Developmental changes in KCNQ2 and KCNQ3 expression in human brain: Possible contribution to the age-dependent etiology of benign familial neonatal convulsions
Keywords: Epilepsy; KCNQ; M-current; Benign neonatal convulsions; Neuropathology
Retigabine-induced population primary afferent hyperpolarisation in vitro
Keywords: Retigabine; XE-991; KCNQ; Spinal cord; Primary afferent fibres; Dorsal root reflexes
The corticosteroid hormone induced factor: A new modulator of KCNQ1 channels?
Keywords: KCNQ; Voltage-regulated; IV-relation; Channel; β-Subunit; KCNE; FXYD; CHIF; Kidney; Colon; Aldosterone
Firing pattern and calbindin-D28k content of human epileptic granule cells
Keywords: Afterhyperpolarization; Spike frequency adaptation; Gramicidin, Perforated patch; Granule cell; Dentate gyrus; Temporal lobe epilepsy; Calcium binding protein; KCNQ; IM
Dorsal root ganglion neurones in culture: A model system for identifying novel analgesic targets?
Keywords: Dorsal root ganglia (DRG); Ion channel; KCNQ; Nociceptor; Patch clamp; Pain; Methods;
The use of Chinese hamster ovary (CHO) cells in the study of ion channels
Keywords: Methods; CHO cells; KCNQ; Potassium channels; Transfection; Patch clamp; Muscarinic receptors; ENaC;
Electrophysiological and molecular identification of hepatocellular volume-activated K+ channels
Keywords: cDNA; Human; KCNE; KCNQ; Patch clamp; Rat; RVD;