دانلود مقالات ISI درباره LBD، دامنه اتصال لیگاند + ترجمه فارسی

ارزیابی فارماکولوژیک مکانیسم های درگیر در افزایش چربی دریایی در ماهی قزل آلا ناشی از آلودگی محیط زیست تبتالیتین

Pharmacological evaluation of the mechanisms involved in increased adiposity in zebrafish triggered by the environmental contaminant tributyltin

Keywords: LBD، دامنه اتصال لیگاند; DBD, DNA-binding domain; DMSO, dimethylsulfoxide; DHA, docosahexaenoic acid; ER, estrogen receptor; HFD, high fat diet; LBD, ligand-binding domain; LXR, liver X receptor; MSC, multipotent stromal stem cell; NR, nuclear receptor; PPAR, peroxisome prolifera

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

بررسی خواص عملکردی و محلی سازی سلول های محلی گیرنده های استروژن ماهی قزل آلا و رنگین کمان در داخل یک سلول مخلوط مخمر منحصر به فرد

Investigation of the functional properties and subcellular localization of alpha human and rainbow trout estrogen receptors within a unique yeast cellular context

Keywords: LBD، دامنه اتصال لیگاند; E2, 17β-estradiol; ES, estrogens; ER, estrogen receptor; ERE, estrogen response element; LBD, ligand-binding domain; DBD, DNA-binding domain; EREcs, consensus estrogen response element; hERα, human estrogen receptor alpha subtype; rtERαS, short isoform of

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

E17110 promotes reverse cholesterol transport with liver X receptor β agonist activity in vitro

Keywords: LBD، دامنه اتصال لیگاند; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; ApoA-I, apolipoprotein A-I; GAPDH, glyceraldehyde-phosphate dehydrogenase; HDL, high-density lipoprotein; LBD, ligand-binding domain; LXR, liver X receptor; LXRE, LXR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of glabridin as a bioactive compound in licorice (Glycyrrhiza glabra L.) extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ)

Keywords: LBD، دامنه اتصال لیگاند; FABP1, human fatty acid binding protein 1; HMGCS2, 3-hydroxy-3-methylglutaryl-CoA synthase 2; HPRT1, hypoxanthine phosphoribosyltransferase; LBD, ligand-binding domain; PCK1, phosphoenolpyruvate carboxykinase 1; PPAR, peroxisome proliferator-activated rec

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular dynamics study-based mechanism of nefiracetam-induced NMDA receptor potentiation

Keywords: LBD، دامنه اتصال لیگاند; LBD, ligand-binding domain; GLUN1, subunit 1 of NMDA receptor; TMD, transmembrane domain; BSP-SLIM, binding site prediction-shape-based ligand matching with binding pocketNMDA receptor; Nefiracetam; Threonine-647; Gauche trap; Molecular dynamics

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Peroxisome proliferator-activated receptor alpha1 in yellow catfish Pelteobagrus fulvidraco: Molecular characterization, mRNA tissue expression and transcriptional regulation by insulin in vivo and in vitro

Keywords: LBD، دامنه اتصال لیگاند; BW, body weight; DBD, DNA-binding domain; FBS, fetal bovine serum; LBD, ligand-binding domain; NJ, neighbor-joining; ORF, open reading frame; PPAR, peroxisome proliferator-activated receptor; RACE, rapid amplification of cDNA ends; RT-PCR, reverse transcr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Peroxisome proliferator-activated receptor gamma (PPARγ) in yellow catfish Pelteobagrus fulvidraco: Molecular characterization, mRNA expression and transcriptional regulation by insulin in vivo and in vitro

Keywords: LBD، دامنه اتصال لیگاند; aa, amino acid; DBD, DNA-binding domain; LBD, ligand-binding domain; NJ, neighbor-joining; nt, nucleotide; ORF, open reading frame; PPAR, peroxisome proliferator-activated receptor; RACE, rapid amplification of cDNA ends; SEM, standard errors of means; UT

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

How Hsp70 Molecular Machines Interact with Their Substrates to Mediate Diverse Physiological Functions

Keywords: LBD، دامنه اتصال لیگاند; SBD, substrate-binding domain; NBD, nucleotide-binding domain; EM, electron microscopy; GR, glucocorticoid receptor; LBD, ligand-binding domain; ER, endoplasmic reticulumHsp70 molecular chaperone; chaperone substrates; protein folding; disaggregation; com

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Structural design and synthesis of arylalkynyl amide-type peroxisome proliferator-activated receptor γ (PPARγ)-selective antagonists based on the helix12-folding inhibition hypothesis

Keywords: LBD، دامنه اتصال لیگاند; PPARγ; PPARγ antagonist; Agonist–antagonist switching; Rational design; Helix12 folding inhibition hypothesisNR, nuclear receptor; PPAR, peroxisome proliferator-activated receptor; LBD, ligand-binding domain; H12, helix12

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of thyroid hormone receptor homologs in the fluke Opisthorchis felineus (Platyhelminthes)

Keywords: LBD، دامنه اتصال لیگاند; THR, thyroid hormone receptor; LBD, ligand-binding domain; T3, triiodothyronine; T4, thyroxineHost–parasite interaction; Thyroid hormone receptor; Trematoda

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Fish granulocytes express a constitutively active androgen receptor variant

Keywords: LBD، دامنه اتصال لیگاند; AR, androgen receptor; T, testosterone; 11KT, 11-ketotestosterone; E2, 17β-estradiol; NTD, amino-terminal domain; DBD, DNA-binding domain; LBD, ligand-binding domain; RCs, reproductive cycles; SG, spermatogenesis; S, spawning; PS, post-spawning; R, restin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish

Keywords: LBD، دامنه اتصال لیگاند; Aryl hydrocarbon receptor (AHR); Cardiotoxicity; Firemaster 550; Flame retardant; Zebrafish; CH223191AHR, aryl hydrocarbon receptor; CYP1A, cytochrome P450 1A; FM550, Firemaster 550; IHC, immunohistochemistry; LBD, ligand-binding domain; mITP, mono-substi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor

Keywords: LBD، دامنه اتصال لیگاند; HTS, high-throughput screen; FXR, farnesoid X receptor; NRs, nuclear receptors; Cyp7A1, cytochrome 7A1; BAs, bile acids; BSEP, bile salt export pump; SAR, structure–activity relationship; LBD, ligand-binding domain

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

Cyanidin is an agonistic ligand for peroxisome proliferator-activated receptor-alpha reducing hepatic lipid

Keywords: LBD، دامنه اتصال لیگاند; PPAR, peroxisome proliferated-activated receptor; LBD, ligand-binding domain; RXR, retinoid X receptor; Apo, apolipoprotein; KD, equilibrium dissociation constant; EC50, the half maximal effective concentration; SPR, surface plasmon resonance; TR-FRET, ti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular determinants for nuclear receptors selectivity: Chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors α/γ agonists

Keywords: LBD، دامنه اتصال لیگاند; Peroxisome proliferator-activated receptors; Selectivity; Docking; GRIND; 3D-QSAR; MutagenesisMS, metabolic syndrome; CVD, cardiovascular disease; LBD, ligand-binding domain; SDM, site directed mutagenesis; DOPE, discrete optimized protein energy; MIFs, m

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Design and synthesis of a series of α-benzyl phenylpropanoic acid-type peroxisome proliferator-activated receptor (PPAR) gamma partial agonists with improved aqueous solubility

Keywords: LBD، دامنه اتصال لیگاند; NR, nuclear receptor; hPPAR, human peroxisome proliferator-activated receptor; LBD, ligand-binding domain; PDB, protein data bank3VSO; hPPARγ LBD-(R)-7JHuman peroxisome proliferator-activated receptor; PPAR gamma; Partial agonist; Structural biology

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis and SAR study of modulators inhibiting tRXRα-dependent AKT activation

Keywords: LBD، دامنه اتصال لیگاند; RXRα; tRXRα modulator; AKT activation; Sulindac analogsRXRα, retinoid X receptor alpha; tRXRα, N-terminally-truncated retinoid X receptor alpha; PI3K, phosphatidylinositol-3-OH kinase; NR, nuclear receptor; LBD, ligand-binding domain; LBP, ligand-binding

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

A large deletion/insertion-induced frameshift mutation of the androgen receptor gene in a family with a familial complete androgen insensitivity syndrome

Keywords: LBD، دامنه اتصال لیگاند; AIS, Androgen insensitivity syndrome; AR, androgen receptor; BLAST, Basic Local Alignment Search Tool; CAIS, complete androgen insensitivity syndrome; DBD, DNA-binding domain; LBD, ligand-binding domain; NTD, N-terminal domain; PAIS, partial androgen inse

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

A comparison of glycine- and ivermectin-mediated conformational changes in the glycine receptor ligand-binding domain

Keywords: LBD، دامنه اتصال لیگاند; AF546, Alexa Fluor 546C5 maleimide; GlyR, glycine receptor; LBD, ligand-binding domain; MTS-R, sulforhodamine methanethiosulfonate; MTS-TAMRA, 2-((5(6)-tetramethylrhodamine) carboxylamino)ethyl methanethiosulfonate; TMD, transmembrane domain; TMRM, tetram

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Negative regulation of ERRα by a novel nucleolar protein

Keywords: LBD، دامنه اتصال لیگاند; ERR, estrogen-related receptor; RaRF, retinoic acid resistance factor; AD, transcriptional activation domain; DBD, DNA-binding domain; LBD, ligand-binding domain; IP, immunoprecitation; WB, Western blotting; GST, glutathione S-transferase; β-gal, β-galact

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Highly potent binding and inverse agonist activity of bisphenol A derivatives for retinoid-related orphan nuclear receptor RORγ

Keywords: LBD، دامنه اتصال لیگاند; BP, bisphenol; ER, estrogen receptor; ERR, estrogen-related receptor; 25-HC, 25-hydroxycholesterol; LBD, ligand-binding domain; LBP, ligand-binding pocket; PPAR, peroxisome proliferator-activated receptor; RORγ, retinoid-related orphan receptors γEndocrin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Androgen receptor repression of gonadotropin-releasing hormone gene transcription via enhancer 1

Keywords: LBD، دامنه اتصال لیگاند; cs, charcoal/dextran-treated; DBD, DNA-binding domain; DHT, 5α-dihydrotestosterone; GnRH-E, GnRH enhancer; GnRH-P, GnRH promoter; HPG, hypothalamic-pituitary-gonadal; LBD, ligand-binding domain; MMTV, mouse mammary tumor virus; Nkx2.1, NK2 homeobox 1; Oct

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Intrinsic Motions in the N-Terminal Domain of an Ionotropic Glutamate Receptor Detected by Fluorescence Correlation Spectroscopy

Keywords: LBD، دامنه اتصال لیگاند; ACF, autocorrelation function; AMPA, α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; AMPAR, AMPA receptor; BSA, bovine serum albumin; FCS, fluorescence correlation spectroscopy; iGluR, ionotropic glutamate receptor; LBD, ligand-binding domain; NMDA, N

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Molecular determinants of the interactions between SRC-1 and LXR/RXR heterodimers

Keywords: LBD، دامنه اتصال لیگاند; 9cisRA, 9-cis retinoic acid; 22ROHC, 22(R)-hydroxycholesterol; AF2, activation function 2; MBP, maltose-binding protein; LBD, ligand-binding domain; LXR, liver X receptor; NR, nuclear receptor; NR box-1/-2/-3, the first/second/third NR box of SRC-1, respe

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Identification of a novel human thyroid hormone receptor β isoform as a transcriptional modulator

Keywords: LBD، دامنه اتصال لیگاند; CoA, coactivator protein; CoR, corepressor protein; DBD, DNA-binding domain; FBS, fetal bovine serum; LBD, ligand-binding domain; Luc, luciferase; RTH, resistance to thyroid hormone; TK, thymidine kinase; TR, thyroid hormone receptor; TRE, thyroid hormone

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Regulation of Nur77 protein turnover through acetylation and deacetylation induced by p300 and HDAC1

Keywords: LBD، دامنه اتصال لیگاند; HAT, histone acetyltransferase; HDAC, histone deacetylase; IP, immunoprecipitation; TSA, trichostatin A; DBD, DNA-binding domain; LBD, ligand-binding domain; NGF, nerve growth factor; EGF, epithelial growth factor; PMA, phorbol myristate acetate; CHX, cyc

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening

Keywords: LBD، دامنه اتصال لیگاند; hGR-LBD, human glucocorticoid receptor ligand-binding domain; FACS, fluorescence-activated cell sorting; eGFP, enhanced green fluorescent protein; GR, glucocorticoid receptor; LBD, ligand-binding domain; mGR-LBD, mouse glucocorticoid receptor ligand-bindi

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Atomic structure of mutant PPARγ LBD complexed with 15d-PGJ2: Novel modulation mechanism of PPARγ/RXRα function by covalently bound ligands

Keywords: LBD، دامنه اتصال لیگاند; PPARγ, peroxisome proliferators-activated receptor γ; RXR, retinoid X receptor; 15d-PGJ2, 15-deoxy-Δ12,14-prostaglandin J2; LBD, ligand-binding domain; LBP, ligand-binding pocket; DBD, DNA-binding domainPPARγ; covalently bound ligand; PPARγ/RXRα; activati

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARγ activation

Keywords: LBD، دامنه اتصال لیگاند; PPAR, peroxisome proliferator-activated receptor; TG, triacylglyceride; DBD, DNA-binding domain; LBD, ligand-binding domain; MM, maintenance medium; DM, differentiation medium; LPL, lipoprotein lipase; 2DG, 2-deoxy-glucoseBixin; Norbixin; PPAR; Adipocyte;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Anti-androgen activity of polybrominated diphenyl ethers determined by comparative molecular similarity indices and molecular docking

Keywords: LBD، دامنه اتصال لیگاند; BDE, Brominated diphenyl ether; PBDEs, Polybrominated diphenyl ethers; 3D-QSAR, Three-dimensional quantitative structure-activity relationship; CoMSIA, Comparative molecular similarity indices analysis; AR, Androgen receptor; LBD, Ligand-binding domain; P

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Exploration of endocrine-disrupting chemicals on estrogen receptor α by the agonist/antagonist differential-docking screening (AADS) method: 4-(1-Adamantyl)phenol as a potent endocrine disruptor candidate

Keywords: LBD، دامنه اتصال لیگاند; AADS, the agonist/antagonist differential-docking screening; AF2, activation function 2; Cpf, conformation preference factor; EDC, endocrine-disrupting chemical; ERα, estrogen receptor α; LBD, ligand-binding domain; LBP, ligand-binding pocket; NR, nuclear

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

INT131: A Selective Modulator of PPARγ

Keywords: LBD، دامنه اتصال لیگاند; peroxisome proliferator-activated receptor γ; T131; INT131; TZD; diabetesPPARγ, peroxisome proliferator-activated receptor γ; TZD, thiazolidinedione; LBD, ligand-binding domain; Gal4-UAS, Gal4 upstream-activating sequence; LXR, liver X receptor; HTRF, hom

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Helix 3–helix 5 interactions in steroid hormone receptor function

Keywords: LBD، دامنه اتصال لیگاند; hPR, human progesterone receptor; hGR, human glucocorticoid receptor; hMR, human mineralocorticoid receptor; LBD, ligand-binding domain; NR, nuclear receptor; H3, helix 3; H5, helix 5; vdW, van der Waals

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Nuclear receptors in Bombyx mori: Insights into genomic structure and developmental expression

Keywords: LBD، دامنه اتصال لیگاند; Bombyx mori; Nuclear receptor; Structure; Expression; MetamorphosisNR, nuclear receptor; LBD, ligand-binding domain; DBD, DNA-binding domain; SNP, single nucleotide polymorphisms; WGS, whole genome sequence; Bm, Bombyx mori; Dm, Drosophila melanogaster; A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

3,3′,5-Triiodo-l-thyronine-like activity in effluents from domestic sewage treatment plants detected by in vitro and in vivo bioassays

Keywords: LBD، دامنه اتصال لیگاند; BTEB, basic transcription element-binding protein; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GST, glutathione-S-transferase; HPLC, high-performance liquid chromatography; LBD, ligand-binding domain; Luc, luciferase; MEC, minimum effective concentra

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Induced-fit docking of mometasone furoate and further evidence for glucocorticoid receptor 17α pocket flexibility

Keywords: LBD، دامنه اتصال لیگاند; des-CIC, desisobutyryl-ciclesonide; Dex, dexamethasone; FF, fluticasone furoate; FP, fluticasone propionate; GC, glucocorticoid; GR, glucocorticoid receptor; IFD, induced-fit docking; LBD, ligand-binding domain; MF, mometasone furoate; PDB, Protein Data B

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Discovery of substituted sulfonamides and thiazolidin-4-one derivatives as agonists of human constitutive androstane receptor

Keywords: LBD، دامنه اتصال لیگاند; CAR, constitutive androstane receptor; CITCO, 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)-oxime; CYP, cytochrome P450; EE2, 17α-ethynyl-3,17β-estradiol; H12, helix 12; LBD, ligand-binding domain; LBP, ligand-binding

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Crystal Structures of the Streptomyces coelicolor TetR-Like Protein ActR Alone and in Complex with Actinorhodin or the Actinorhodin Biosynthetic Precursor (S)-DNPA

Keywords: LBD، دامنه اتصال لیگاند; (S)-DNPA, 4-dihydro-9-hydroxy-1-methyl-10-oxo-3-H-naphtho-[2,3-c]-pyran-3-(S)-acetic acid; DBD, DNA-binding domain; LBD, ligand-binding domain; SeMet, selenomethionine; PEG, polyethylene glycol; PDB, Protein Data BankTetR transcriptional regulators; antib

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Deoxyelephantopin inhibits cancer cell proliferation and functions as a selective partial agonist against PPARγ

Keywords: LBD، دامنه اتصال لیگاند; ESD, deoxyelephantopin; PPARγ, peroxisome proliferator-activated receptor-γ; TZDs, thiazolidinediones; NF-κB, nuclear factor-κB; LBD, ligand-binding domain; AF-2, ligand-dependent activation domain; SRC-1, steroid receptor coactivator-1; CBP, cAMP-respons

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Controlling the chromatin organization of vitamin D target genes by multiple vitamin D receptor binding sites

Keywords: LBD، دامنه اتصال لیگاند; 1α,25(OH)2D3, 1α,25-dihydroxy vitamin D3; ChIP, chromatin immunoprecipitation; CoA, co-activator; CoR, co-repressor; CYP, cytochrome P450; DR, direct repeat; ER, everted repeat; IGFBP, insulin-like growth factor binding protein; LBD, ligand-binding domain

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Phylogenetic conservation of the androgen receptor AR45 variant form in placental mammals

Keywords: LBD، دامنه اتصال لیگاند; AR, androgen receptor; DBD, DNA-binding domain; ER, estrogen receptor; GR, glucocorticoid receptor; LBD, ligand-binding domain; MR, mineralocorticoid receptor; PR, progesterone receptor.Androgen receptor; Steroid receptors; Phylogeny; Exon; Alternative sp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Highly sensitive upregulation of apolipoprotein A-IV by peroxisome proliferator-activated receptor α (PPARα) agonist in human hepatoma cells

Keywords: LBD، دامنه اتصال لیگاند; AOX, acyl-CoA oxidase; apo, apolipoprotein; CHO-K1, Chinese hamster ovary-K1; CPT1A, carnitine palmitoyltransferase 1A; DMEM, Dulbecco's modified Eagle's medium; HDL, high-density lipoprotein; LBD, ligand-binding domain; L-FABP, liver fatty acid binding p

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Post-translational modifications of steroid receptors

Keywords: LBD، دامنه اتصال لیگاند; Steroid receptor; Phosphorylation; Acetylation; Ubiquitylation; SumoylationAR, androgen receptor; CDK, cyclin-dependent kinase; DBD, DNA-binding domain; ER, estrogen receptor; GR, glucocorticoid receptor; LBD, ligand-binding domain; MR, mineralocorticoid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Recombinant Human PPAR-β/δ Ligand-binding Domain is Locked in an Activated Conformation by Endogenous Fatty Acids

Keywords: LBD، دامنه اتصال لیگاند; crystal structure; fatty acid; ligand-binding domain; mass spectrometry; nuclear receptorPPAR, peroxisome proliferator-activated receptor; LBD, ligand-binding domain; FA, fatty acid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Classification and comparison of ligand-binding sites derived from grid-mapped knowledge-based potentials

Keywords: LBD، دامنه اتصال لیگاند; AR, androgen receptor; LBD, ligand-binding domain; NR, nuclear receptor; PCA, principal component analysis; PLS, partial least squares; PPAR, peroxisome proliferator-activated receptor; PR, progesterone receptor; RMSD, root mean square deviationMolecular

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Structural basis for androgen receptor agonists and antagonists: Interaction of SPEED 98-listed chemicals and related compounds with the androgen receptor based on an in vitro reporter gene assay and 3D-QSAR

Keywords: LBD، دامنه اتصال لیگاند; AR, androgen receptor; ER, estrogen receptor; LBD, ligand-binding domain; DHT, dihydrotestosterone; PR, progesterone receptor; GR, glucocorticoid receptor; QSAR, quantitative structure–activity relationships; SAR, structure–activity relationships; CoMFA,

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه