LncRNA, miRNA and lncRNA-miRNA interaction in viral infection
Keywords: lncRNAs; miRNAs; Virus; Regulatory;
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LncRNA MALAT1 is up-regulated in diabetic gastroparesis and involved in high-glucose-induced cellular processes in human gastric smooth muscle cells
Keywords: Diabetic gastroparesis; Human gastric smooth muscle cells; lncRNA MALAT1; High-glucose stimulation; DGP; Diabetic gastroparesis; DM; diabetes mellitus; GI; gastrointestinal; ICC; interstitial cells of Cajal; SMCs; smooth muscle cells; SM-MHC; SM myosin he
A novel lncRNA, Lnc-OC1, promotes ovarian cancer cell proliferation and migration by sponging miR-34a and miR-34c
Keywords: Ovarian cancer; Lnc-OC1; miR-34a; miR-34c; Tumorigenicity; ceRNA; competing endogenous RNAs; EMT; epithelial-mesenchymal transition; GEO; Gene Expression Omnibus; LncRNAs; long non-coding RNAs; miRNA; microRNA; OC; ovarian cancer; RNA-FISH; RNA-fluorescen
Long noncoding RNA SNHG12 facilitates the tumorigenesis of glioma through miR-101-3p/FOXP1 axis
Keywords: lncRNAs; long noncoding RNAs; Glioma; SNHG12; miR-101-3p; FOXP1;
Long non-coding RNA DILC suppresses cell proliferation and metastasis in colorectal cancer
Keywords: CRC; Colorectal cancer; lncRNAs; Long non-coding RNAs; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; EdU; 5-ethynyl-2â²-deoxyuridine; APC; adenomatous polyposis coli; LCSC; liver cell stem cells; Colorectal cancer; lnc-DILC; STAT3; P
Regulatory network analysis of high expressed long non-coding RNA LINC00941 in gastric cancer
Keywords: lncRNAs; Long non-coding RNAs; GC; gastric cancer; WHO; World Health Organization; HOTAIR; HOX Transcript Antisense RNA; EGFR; epidermal growth factor receptor; H19; MATERNALLY EXPRESSED TRANSCRIPT; HULC; hepatocellular carcinoma up-regulated lncRNA; CCAT
Identification of a novel antisense long non-coding RNA PLA2G16-AS that regulates the expression of PLA2G16 in pigs
Keywords: NATs; natural antisense transcripts; PLA2G16; phospholipase A2 group XVI; lncRNAs; long non-coding RNAs; VIM; vimentin; VIM-AS1; VIM antisense transcript1; BACE1; β-site APP-cleaving enzyme 1; BACE1-AS; BACE1 antisense transcript; PLA2G16-AS; PLA2G16 ant
The overlap between regeneration and fibrosis in injured skeletal muscle is regulated by phosphatidylinositol 3-kinase/Akt signaling pathway - A bioinformatic analysis based on lncRNA microarray
Keywords: lncRNAs; Long noncoding RNA; PI3K/Akt; Phosphatidylinositol 3-kinase/Akt; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; TA; Tibialis anterior; PCC; Pearson correlation coefficient; FDR; False discovery rate; rt-PCR; Reverse transcripta
Long intergenic non-protein coding RNA 319 aggravates lung adenocarcinoma carcinogenesis by modulating miR-450b-5p/EZH2
Keywords: lncRNAs; long noncoding RNAs; ceRNA; competing endogenous RNAs; miR-363-5p; hsa-miRNA-450b-5p; LINC00319; long intergenic non-protein coding RNA 319; ANOVA; One-Way Analysis of Variance; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IHC; immunohistoche
Genetic variants in long noncoding RNA H19 and MEG3 confer risk of type 2 diabetes in an Iranian population
Keywords: DN; diabetes mellitus; T2D; type 2 diabetes; GWAS; genome-wide association studies; SNPs; single nucleotide polymorphisms; lncRNAs; long-noncoding RNAs; miRNA; microRNA; MEG3; maternally expressed 3; PCR-RFLP; polymerase chain reaction-restriction fragmen
Investigation of candidate long noncoding RNAs and messenger RNAs in the immediate phase of spinal cord injury based on gene expression profiles
Keywords: SCI; spinal cord injury; lncRNAs; long noncoding RNAs; mRNAs; messenger RNAs; DE lncRNAs; differentially expressed lncRNAs; DE mRNAs; differentially expressed mRNAs; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; PPI; protein-protein in
Jejunal long noncoding RNAs are associated with glycemic control via gut-brain axis after bariatric surgery in diabetic mice
Keywords: lncRNAs; Gut-brain axis; Microarray; Type 2 diabetes (T2D); Metabolic and bariatric surgery;
Novel long noncoding RNA NMR promotes tumor progression via NSUN2 and BPTF in esophageal squamous cell carcinoma
Keywords: LncRNAs; ESCC; Oncogenesis; Metastasis; Drug resistance;
Long non-coding RNA FOXD2-AS1 aggravates nasopharyngeal carcinoma carcinogenesis by modulating miR-363-5p/S100A1 pathway
Keywords: lncRNAs; long noncoding RNAs; NPC; nasopharyngeal carcinoma; EMT; epithelial-to-mesenchymal transition; ceRNA; competing endogenous RNAs; miR-363-5p; hsa-miRNA-363-5p; ANOVA; One-Way Analysis of Variance; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; I
lncRNAs as potential molecular biomarkers for the clinicopathology and prognosis of glioma: A systematic review and meta-analysis
Keywords: lncRNAs; long noncoding RNAs; UCA1; urothelial carcinoma associated 1; OR; odds ratio; CI; confidence interval; WHO; World Health Organization; MALAT1; metastasis-associated lung adenocarcinoma transcript 1; OS; overall survival; HR; hazard ratio; RR; rel
Long Noncoding RNA SNHG1 Promotes Neuroinflammation in Parkinson's Disease via Regulating miR-7/NLRP3 Pathway
Keywords: lncRNAs; long noncoding RNAs; LPS; lipopolysaccharide; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NLRP3; nod-like receptor protein 3; PD; Parkinson's disease; SNHG1; small nucleolar RNA host gene 1; SNpc; substantia nigra pars compacta; TNF; tu
Epigenetics of breast cancer: Biology and clinical implication in the era of precision medicine
Keywords: BC; breast Cancer; ER; estrogen Receptor; PgR,PR; progesteron receptor; HER-2; human epidermal growth factor receptor 2; TNBC; triple negative breast cancer; ncRNA; non coding RNA; CpG(s); cytosine-phosphate-guanine dinucleotide(s); 5-me-C; 5-methyl-cytos
Long non-coding RNA CHRF facilitates cardiac hypertrophy through regulating Akt3 via miR-93
Keywords: ceRNA; competing endogenous RNA; lncRNAs; long non-coding RNAs; CHRF; cardiac hypertrophy related factor; TAC; transverse aortic constriction; β-MHC; β-myosin heavy chain; ANP; atrial natriuretic peptide; Iso; isoproterenol; lncRNA; Cardiac hypertrophy;
Long Noncoding RNA uc.173 Promotes Renewal of the Intestinal Mucosa by Inducing Degradation of MicroRNA 195
Keywords: lncRNAs; IEC; Post-transcriptional Regulation; Mouse Model; BrdU; bromodeoxyuridine; DFMO; D,L-α-difluoro-methylornithine; FISH; fluorescence in situ hybridization; IEC; intestinal epithelial cell; LNA; locked nucleic acid; lncRNA; long noncoding RNAs; L
Engineered exosomes: A new promise for the management of musculoskeletal diseases
Keywords: Engineered exosomes; Drug delivery; Musculoskeletal diseases; Regenerative medicine; Oncology; Immune system regulation; 3â²UTR; 3â²untranslated regions; 6-OHDA; 6-hydroxydopamine; APC; adenomatous polyposis coli; BRD7; bromo-domain-containing protein 7
LncRNAs and CircRNAs from the same gene: Masterpieces of RNA splicing
Keywords: LncRNAs; CircRNAs; microRNA sponge; Competing endogenous RNA; RNA splicing;
Baicalein inhibits cervical cancer progression via downregulating long noncoding RNA BDLNR and its downstream PI3Â K/Akt pathway
Keywords: lncRNAs; long noncoding RNAs; BDLNR; baicalein down regulated long noncoding RNA; FBS; fetal bovine serum; RACE; rapid amplification of cDNA ends; qRT-PCR; quantitative real-time polymerase chain reaction; EdU; ethynyl deoxyuridine; TUNEL; TdT-mediated dU
The C/EBPβ-LINC01133 axis promotes cell proliferation in pancreatic ductal adenocarcinoma through upregulation of CCNG1
Keywords: LINC01133; CCAAT/enhancer-binding protein β; Cyclin G1; Pancreatic ductal adenocarcinoma; PDAC prognostic biomarker; LncRNAs; Long non-coding RNAs; PDAC; pancreatic ductal adenocarcinoma; C/EBPβ; CCAAT/enhancer-binding protein β; CCNG1; cyclin protein
The long noncoding RNA expression profiles of paroxysmal atrial fibrillation identified by microarray analysis
Keywords: lncRNAs; long noncoding RNAs; PAF; paroxysmal atrial fibrillation; qRT-PCR; quantitative real-time PCR; lincRNAs; large intergenic non-coding RNAs; CARL; cardiac-apoptosis related lncRNA; MALAT1; metastasis-associated lung adenocarcinoma transcript 1; HIF
Isolation of the sex-determining gene Sex-lethal (Sxl) in Penaeus (Litopenaeus) vannamei (Boone, 1931) and characterization of its embryogenic, gametogenic, and tissue-specific expression
Keywords: Sxl; Sex-lethal; SS; Splice site; tra; transformer; tra-2; transformer-2; dsx; doublesex; dmrt; doublesex and mab-3 related transcription factor; QTL; quantitative trait locus; PFA; paraformaldehyde; PBS; phosphate buffered saline; RNA; ribonucleic acid;
Long non-coding RNAs in coronary atherosclerosis
Keywords: LncRNAs; Coronary atherosclerosis; Cellular dysfunction; Metabolic disorders; Immune inflammatory response;
Long non-coding RNAs regulation in adipogenesis and lipid metabolism: Emerging insights in obesity
Keywords: lncRNAs; Obesity; White adipogenesis; Brown adipocyte differentiation; Lipid metabolism; Therapeutics; WAT; white adipose tissue; BAT; brown adipose tissue; Pparg; peroxisome proliferator-activated receptor γ; Cebpa; CCAAT/enhancer binding protein α; Fa
Targeting epigenome with dietary nutrients in cancer: Current advances and future challenges
Keywords: Methylation; Acetylation; Histones; miRNAs; lncRNAs; Polyphenols; Epigenome; Natural products;
Cardiac repair by epicardial EMT: Current targets and a potential role for the primary cilium
Keywords: BBS8; Bardet-Biedl syndrome 8; bFGF; basic fibroblast growth factor; BMP; bone morphogenetic protein; BMSCs; bone marrow-derived hematopoietic stem cells; ECM; extracellular matrix; EGF; epidermal growth factor; EMT; epithelial-to-mesenchymal transition;
Angiogenic lncRNAs: A potential therapeutic target for ischaemic heart disease
Keywords: LncRNAs; Therapeutic angiogenesis; Ischaemic heart disease; Angiogenesis;
Meeting report for Odd Pols 2016: Ann Arbor 2.0
Keywords: FGFR2; FGF Receptor-2; hESCs; human embryonic stem cells; lncRNAs; long noncoding RNAs; NORs; Nucleolus Organizer Regions; RdDM; RNA-directed DNA Methylation; Pol I; RNA polymerase I; Pol II; RNA polymerase II; Pol III; RNA polymerase III; Pol IV; RNA pol
H19 mediates methotrexate resistance in colorectal cancer through activating Wnt/β-catenin pathway
Keywords: CRC; colorectal cancer; DHFR; dihydrofolate reductase; DMEM; Dulbecco's modified Eagle's medium; lncRNAs; long or large noncoding RNAs; HT-29-R; MTX-resistant colorectal cell line HT-29; MDR1; multi-drug resistance 1; MTT; 3-(4,5-Dimethylthiazol-2-yl)-2,5
Upregulation of the long non-coding RNA SPRY4-IT1 indicates a poor prognosis and promotes tumorigenesis in ovarian cancer
Keywords: lncRNAs; Long noncoding RNAs; qRT-PCR; quantitative real-time polymerase chain reaction; OS; overall survival; PFS; progression-free survival; OC; Ovarian cancer; ROC; Receiver operating characteristic; Long non-coding RNA; SPRY4-IT1; Ovarian cancer; Prog
Long non-coding RNAs: The novel diagnostic biomarkers for leukemia
Keywords: lncRNAs; long non-coding RNAs; ncRNAs; non-coding RNAs; AL; acute leukemia; CL; chronic leukemia; AML; acute myeloid leukemia; ALL; acute lymphoblastic leukemia; CML; chronic myeloid leukemia; CLL; chronic lymphoblastic leukemia; mlncRNA; mRNA-like noncod
EZH2-mediated α-actin methylation needs lncRNA TUG1, and promotes the cortex cytoskeleton formation in VSMCs
Keywords: LncRNAs; long non-coding RNAs; TUG1; taurine up-regulated gene 1; VSMCs; vascular smooth muscle cells; SENCR; smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA; Ang II; angiotensin II; PRC2; polycomb repr
The nuclear protein-coding gene ANKRD23 negatively regulates myoblast differentiation
Keywords: MRFS; myogenic regulatory factors; MARP; muscle ankyrin repeat protein; CARP; cardiac ankyrin repeat protein; Ankrd2; Ankyrin repeat domain protein2; ANKRD23; diabetes related ankyrin repeat protein; MyoG; myogenin; LncRNAs; long non-coding RNAs; MLP; mus
ReviewThe role of a new class of long noncoding RNAs transcribed from ultraconserved regions in cancer
Keywords: lncRNAs; miRNAs; T-UCRs; Cancer;
Low expression of long noncoding RNA CASC2 indicates a poor prognosis and promotes tumorigenesis in thyroid carcinoma
Keywords: lncRNAs; long noncoding RNA; OS; overall survival; qRT-PCR; quantitative real-time polymerase chain reaction; ROC; receiver operating characteristic; Thyroid carcinoma; Long noncoding RNAs; CASC2; Prognosis;
Introduction of novel splice variants for CASC18 gene and its relation to the neural differentiation
Keywords: EST; primary expressed sequence tag; lncRNAs; long non-coding RNAs; FBS; fetal bovine serum; RA; retinoic acid; PcG; Polycomb group; CASC18 gene; Long non-coding RNA; NT2 differentiation, Oct4-A gene;
Genome-wide analysis of long non-coding RNAs at the mature stage of sea buckthorn (Hippophae rhamnoides Linn) fruit
Keywords: lncRNAs; long non-coding RNAs; DE-lncRNAs; different expression lncRNAs; ncRNAs; noncoding RNAs; CPC; Coding Potential Calculator; FPKM; fragment per kilobase of exon model per Million mapped reads; CIRI; CircRNA identifier; Sea buckthorn; Fruit; lncRNAs;
LncRNA GAS5 controls cardiac fibroblast activation and fibrosis by targeting miR-21 via PTEN/MMP-2 signaling pathway
Keywords: LncRNAs; long noncoding RNAs; GAS5; growth arrest-specific 5; miR-21; microRNA-21; AF; atrial fibrillation; MI; myocardial infarction; CFs; cardiac fibroblasts; ECM; extracellular matrix; Col1A1; type I collagen; α-SMA; smooth muscle alpha-action; PTEN;
Knockdown of linc-OIP5 inhibits proliferation and migration of glioma cells through down-regulation of YAP-NOTCH signaling pathway
Keywords: CCK8; Cell Counting Kit-8; CNS; central nervous system; DMEM; Dulbecco's modified Eagle's medium; GBM; glioblastoma; Hes-1; hairy and enhancer of split-1; Jag-1; Jagged-1; LincRNAs; long intergenic noncoding RNAs; LncRNAs; Long noncoding RNAs; MALAT1; Met
Research ReportExpression signatures of long non-coding RNA in the substantia nigra of pre-symptomatic mouse model of Parkinson's disease
Keywords: Parkinson's disease; lncRNAs; Microarray; Substantia nigra pars compacta;
Long noncoding RNAs in the initiation, progression, and metastasis of hepatocellular carcinoma
Keywords: Long noncoding RNAs; lncRNAs; Noncoding RNA; Hepatocellular carcinoma; HULC; HOTAIR;
Long non-coding RNA FTH1P3 facilitates oral squamous cell carcinoma progression by acting as a molecular sponge of miR-224-5p to modulate fizzled 5 expression
Keywords: lncRNAs; long noncoding RNAs; OSCC; oral squamous cell carcinoma; EMT; epithelial-to-mesenchymal transition; FTH1P3; ferritin heavy chain 1 pseudogene 3; ceRNA; competing endogenous RNAs; miR-224-5p; hsa-miRNA-224-5p; ANOVA; One-Way Analysis of Variance;
LncRNA, TUG1 regulates the oral squamous cell carcinoma progression possibly via interacting with Wnt/β-catenin signaling
Keywords: OSCC; oral squamous cell carcinoma; lncRNAs; long non-coding RNAs; TUG1; taurine upregulated gene 1; EMT; epithelial-to-mesenchymal transition; OSCC; TUG1; Cell proliferation; Apoptosis; Wnt/β-catenin signaling;
LncRNA MALAT1 sponges miR-204 to promote osteoblast differentiation of human aortic valve interstitial cells through up-regulating Smad4
Keywords: lncRNAs; long non-coding RNAs; CAVD; calcific aortic valve disease; qRT-PCR; quantitative reverse transcription- polymerase chain reaction; VICs; valve interstitial cells; FBS; fetal bovine serum; AVR; aortic valve replacement; β-gal; β-galactosidase; 3
Long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1): A molecular predictor of poor survival in glioblastoma multiforme in Egyptian patients
Keywords: DFS; disease-free survival; FFPE; formalin-fixed paraffin embedded; GBM; glioblastoma multiform; lncRNAs; long non-coding RNA; MALAT1; metastasis-associated lung adenocarcinoma transcript 1; NEAT2; nuclear-enriched abundant transcript 2; OS; overall survi
Melanoma long non-coding RNA signature predicts prognostic survival and directs clinical risk-specific treatments
Keywords: lncRNAs; long non-coding RNAs; CM; cutaneous melanoma; OS; overall survival; AJCC; American Joint Committee on Cancer; RFS; relapse-free survival; EGFR; epidermal growth factor receptor; BANCR; BRAF-activated non-protein coding RNA; MAPK; mitogen-activate
Original ArticlelncRNA DANCR promotes tumor progression and cancer stemness features in osteosarcoma by upregulating AXL via miR-33a-5p inhibition
Keywords: DANCR; AXL; Stemness feature; miR-33a-5p; Osteosarcoma; lncRNAs; long noncoding RNAs; DANCR; differentiation antagonizing non-protein coding RNA; CSCs; cancer stem cells; TICs; tumor-initiating cells; EMT; epithelial-to-mesenchymal transition; DFS; diseas