Keywords: MAPK، پروتئین کیناز متیوژن فعال; LPS, lipopolysaccharide; MAPK, mitogen activated protein kinase; NF-κB, nuclear factor kappa-B; SIC, streptococcal inhibitor of complementGastrointestinal mucosa; Epithelial cell; Mucin; Antimicrobial peptide; Pathogen; Evasion
مقالات ISI MAPK، پروتئین کیناز متیوژن فعال (ترجمه نشده)
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Keywords: MAPK، پروتئین کیناز متیوژن فعال; CARD, caspase recruitment domain; ASC, apoptosis-associated speck-like protein containing a CARD; NLR, nucleotide binding domain/leucine rich repeat; NLRP, NLR with pyrin domain; NLRC, NLR with CARD domain; MAPK, mitogen activated protein kinase; TRIF, TI
Keywords: MAPK، پروتئین کیناز متیوژن فعال; ALK, Activin receptor-like kinase; BMP, bone morphogenetic protein; EndoMT, endothelial-to-mesenchymal transition; HO, heterotopic ossification; MAPK, mitogen activated protein kinase; MMP, matrix metalloproteinase; OB, osteoblast; OC, osteoclast; RANK, r
Keywords: MAPK، پروتئین کیناز متیوژن فعال; AGF, angiopoietin related growth factor; FLI, fatty liver index; MAPK, mitogen activated protein kinase; PPARs, peroxisome proliferator activated receptors; PGC-1α, peroxisome proliferator activated receptor ϒ coactivator 1αAngiopoietin related growth fac
Keywords: MAPK، پروتئین کیناز متیوژن فعال; AqPM, aqueous PM suspension; COX, cyclooxygenase; DEP, diesel exhaust particles; HO-1, heme oxygenase-1; MAPK, mitogen activated protein kinase; NAC, N-acetyl cysteine; OC, organic carbon; OE, organic extract; PAH, polycyclic aromatic hydrocarbon; PG, pro
Keywords: MAPK، پروتئین کیناز متیوژن فعال; PG, prostaglandin; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; (TNF)-α, tumor necrosis factor; ERK, extracellular signal-related kinase; TLR, toll-like receptors (TLRs); MAPK, mitogen activated protein kinase; NF-κB, nuclear factor
Human cathelicidin LL-37 inhibits platelet aggregation and thrombosis via Src/PI3K/Akt signaling
Keywords: MAPK، پروتئین کیناز متیوژن فعال; LL-37; Antiplatelet; Antithrombosis; Src/PI3K/Akt signalingAMP, antimicrobial peptide; ADP, adenosine diphosphate; TxA2, thromboxane A2; GPIIb/IIIa, glycoprotein IIb–IIIa; MAPK, mitogen activated protein kinase; PI3K, phosphatidylinositol 3-kinase; SD, Sp
Response of the JAK-STAT signaling pathway to oxygen deprivation in the red eared slider turtle, Trachemys scripta elegans
Keywords: MAPK، پروتئین کیناز متیوژن فعال; Anoxia; Oxidative stress; Hypometabolism; Low oxygenSTAT, signal transducer and activator of transcription; JAK, janus kinase; MAPK, mitogen activated protein kinase; SOCS, suppressors of cytokine signaling; PIAS, protein inhibitors of activated STAT; bcl
Costunolide, an active sesquiterpene lactone, induced apoptosis via ROS-mediated ER stress and JNK pathway in human U2OS cells
Keywords: MAPK، پروتئین کیناز متیوژن فعال; DAPI, 4′,6-diamidino-2-phenylindole; OS, osteosarcoma; ROS, reactive oxygen species; ER, endoplasmic reticulum; MAPK, mitogen activated protein kinase; ERK, extracellular signal-regulated kinase; JNK, c-Jun N-terminal kinase; ASK1, apoptosis signal-regula
Src/Syk/IRAK1-targeted anti-inflammatory action of Torreya nucifera butanol fraction in lipopolysaccharide-activated RAW264.7 cells
Keywords: MAPK، پروتئین کیناز متیوژن فعال; PG, prostaglandin; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; TNF-α, tumor necrosis factor α; ERK, extracellular signal-related kinase; TLR, Toll-like receptors; MAPK, mitogen activated protein kinase; NF-κB, nuclear factor-κB; AP
Elevated RET expression enhances EGFR activation and mediates EGFR inhibitor resistance in head and neck squamous cell carcinoma
Keywords: MAPK، پروتئین کیناز متیوژن فعال; RET; EGFR; TKI resistance; HNSCCRET, rearranged during transfection; EGFR, epidermal growth factor receptor; RTK, receptor tyrosine kinase; TKI, tyrosine kinase inhibitors; GDNF, glial-derived neurotrophic factor; MAPK, mitogen activated protein kinase; H
TCDD and omeprazole prime platelets through the aryl hydrocarbon receptor (AhR) non-genomic pathway
Keywords: MAPK، پروتئین کیناز متیوژن فعال; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; AhR, aryl hydrocarbon receptor; ARNT, aryl hydrocarbon receptor translocator; MAPK, mitogen activated protein kinase; cPLA2, cytosolic phospholipase A2; aNF, alpha naphthoflavone; CH, CH-223192; SB, SB 202190; PR
Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis 12
Keywords: MAPK، پروتئین کیناز متیوژن فعال; IL6, interleukin-6; JAK, Janus kinase; STAT3, signal transducer and activator of transcription 3; PI3K, phosphoinositide 3-kinase; MAPK, mitogen activated protein kinase; LFABP, liver fatty acid binding protein; RS6K, ribosomal S6 kinase; HCC, hepatocellu
Strain differences in stress-induced changes in central CRF1 receptor expression
Keywords: MAPK، پروتئین کیناز متیوژن فعال; CRF, corticotropin-releasing factor; CRFR1 and CRFR2, CRF receptor 1 and 2; ERK, extracellular signal regulated kinase; FC, frontal cortex; GI, gastrointestinal; IBS, Irritable Bowel Syndrome; MAPK, mitogen activated protein kinase; PVN, paraventricular n
Identification of a truncated kinase suppressor of Ras 2 mRNA in sperm
Keywords: MAPK، پروتئین کیناز متیوژن فعال; KSR, kinase suppressor of Ras; ERK, extracellular signal-regulated protein kinase; T-KSR2, testes-kinase suppressor of Ras 2; MAPK, mitogen activated protein kinase; CA, conserved area; SH2, Src homology 2; RACE, rapid amplification of cDNA ends; NDK-1, n
The Schizosaccharomyces pombe Hikeshi/Opi10 protein has similar biochemical functions to its human homolog but acts in different physiological contexts
Keywords: MAPK، پروتئین کیناز متیوژن فعال; EMM, Edinburgh minimal medium; GFP, green fluorescent protein; Imp-αs, importin-α family proteins; Imp-βs, importin-β family proteins; MAPK, mitogen activated protein kinase; NPC, nuclear pore complex; NTR, nucleocytoplasmic transport receptor; SAPK, stre
Identification and expression of microRNA in the brain of hibernating bats, Myotis lucifugus
Keywords: MAPK، پروتئین کیناز متیوژن فعال; C/EBP, ccaat-enhancer-binding protein; KEGG, Kyoto Encyclopedia of Genes and Genomes; limk1, LIM domain kinase 1; mdDA, mesencephalic–diencephalic dopaminergic; miR, microRNA; MAPK, mitogen activated protein kinase; PVDF, polyvinylidenedifluorideNon-codin
The mycotoxin beauvericin induces apoptotic cell death in H4IIE hepatoma cells accompanied by an inhibition of NF-κB-activity and modulation of MAP-kinases
Keywords: MAPK، پروتئین کیناز متیوژن فعال; CAPE, caffeic acid phenylethylester; ERK, extracellular regulated protein kinase; FCS, fetal calf serum; HMBC, heteronuclear multiple bond correlation; MAPK, mitogen activated protein kinase; MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium-brom
Dual contribution of MAPK and PI3K in epidermal growth factor-induced destabilization of thyroid follicular integrity and invasion of cells into extracellular matrix
Keywords: MAPK، پروتئین کیناز متیوژن فعال; TSH, thyroid stimulating hormone; EGF, epidermal growth factor; TGF-β, transforming growth factor-beta; MAPK, mitogen activated protein kinase; ERK, extracellular-regulated kinase; MEK, MAPK/ERK kinase; PI3K, phosphoinositide 3-kinase; EMT, epithelial–mes
BMP-2 induces ATF4 phosphorylation in chondrocytes through a COX-2/PGE2 dependent signaling pathway
Keywords: MAPK، پروتئین کیناز متیوژن فعال; Chondrocytes; BMP-2; COX-2; ATF4BMP, Bone Morphogenic Protein; COX, Cyclooxygenase; ATF, Activating Transcription Factor; ALK, Activin Receptor-like Kinase; MAPK, Mitogen Activated Protein Kinase; TGF, Transforming Growth Factor; TAK, TGF-β Activated Kina
Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3
Keywords: MAPK، پروتئین کیناز متیوژن فعال; DAPI, diamidino-2-phenylindole; MAPK, mitogen activated protein kinase; PARP, poly (ADP-ribose) polymerase; STAT3, signal transducer and activator of transcription 3Apoptosis; Fas; Luteolin; Paclitaxel; STAT3
Cloning, expression and characterization of a gene encoding mitogen activated protein kinase 2 (MPK2) from Tetrahymena thermophila
Keywords: MAPK، پروتئین کیناز متیوژن فعال; MAPK, mitogen activated protein kinase; MPK2, mitogen activated protein kinase 2; GST-MPK2, glutathione-S-transferase tagged MPK2; RACE, rapid amplification of cDNA ends; RT-PCR, reverse transcriptase polymerase chain reactions; AURE, Adenosine- and Uridi
Xylopia aethiopica (Annonaceae) fruit extract suppresses Freund׳s adjuvant-induced arthritis in Sprague-Dawley rats
Keywords: MAPK، پروتئین کیناز متیوژن فعال; DNA, deoxyribonucleic acid; ERK, extracellular signal-regulated kinase; HGB, haemoglobin; HCT, haematocrit; IgG, immunoglobulin G; IL, interleukin; MAPK, mitogen activated protein kinase; NO, nitric oxide; NF-κB, nuclear Factor-κB; PG, prostaglandin; RBC,
Melanin-concentrating hormone induces neurite outgrowth in human neuroblastoma SH-SY5Y cells through p53 and MAPKinase signaling pathways
Keywords: MAPK، پروتئین کیناز متیوژن فعال; MCH, Melanin-concentrating hormone; MCH-R1, Melanin-concentrating hormone receptor 1; MCH-R2, Melanin-concentrating hormone receptor 2; MEK, mitogen activated protein kinase kinase; MAPK, mitogen activated protein kinase; Erk1/2, extracellular signal-regu
DHA supplementation: Current implications in pregnancy and childhood
Keywords: MAPK، پروتئین کیناز متیوژن فعال; DHA, docosahexaenoic acid; LCPUFA, long chain polyunsaturated fatty acids; TLR, toll like receptor; GPR, G-coupled protein receptor; PPARγ, peroxisome proliferator activated receptor-γ; MAPK, mitogen activated protein kinase; NFkB, nuclear factor kappaB;
AP-1 pathway-targeted inhibition of inflammatory responses in LPS-treated macrophages and EtOH/HCl-treated stomach by Archidendron clypearia methanol extract
Keywords: MAPK، پروتئین کیناز متیوژن فعال; PG, prostaglandin; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; (TNF)-α, tumour necrosis factor; ERK, extracellular signal-related kinase; TLR, Toll-like receptor (TLR); MAPK, mitogen activated protein kinase; NF-κB, nuclear factor-
Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells
Keywords: MAPK، پروتئین کیناز متیوژن فعال; AITC, allyl isothiocyanate; EGF, epithelial growth factor; ERK1/2, extracellular signal-regulated protein kinase ½; FCS, fetal calf serum HBS, HEPES buffered saline; MAPK, mitogen activated protein kinase; RR, ruthenium red; SDS, sodium dodecyl sulfate; T
Peroxiredoxin I is a ROS/p38 MAPK-dependent inducible antioxidant that regulates NF-κB-mediated iNOS induction and microglial activation
Keywords: MAPK، پروتئین کیناز متیوژن فعال; ROS, reactive oxygen species; Prx, peroxiredoxin; LPS, lipopolysaccharide; NO, nitric oxide; MAPK, mitogen activated protein kinase; JNK, c-Jun N-terminal kinase; ERK, extracellular signal-regulated kinase; TNF, tumor necrosis factor; PD, Parkinson's dise
SnoN/SkiL expression is modulated via arsenic trioxide-induced activation of the PI3K/AKT pathway in ovarian cancer cells
Keywords: MAPK، پروتئین کیناز متیوژن فعال; As2O3, arsenic trioxide; DMSO, dimethyl sulfoxide; EGFR, epidermal growth factor receptor; FBS, fetal bovine serum; MAPK, mitogen activated protein kinase; p-AKT, phosphorylated protein kinase B; PARP, poly(ADP-ribose) polymerase; PBS, phosphate buffered
Insulin resistance: An adaptive mechanism becomes maladaptive in the current environment — An evolutionary perspective
Keywords: MAPK، پروتئین کیناز متیوژن فعال; MS, metabolic syndrome; DM2, type 2 diabetes mellitus; CVD, cardiovascular disease; TGs, triglycerides; IRS, insulin receptor substrates; PI3K, phosphatidylinositol 3-kinase; Akt/PKB, Protein kinase B; MAPK, mitogen activated protein kinase; JNK, c-Jun am
The transmembrane protein Opy2 mediates activation of the Cek1 MAP kinase in Candida albicans
Keywords: MAPK، پروتئین کیناز متیوژن فعال; MAPK, Mitogen Activated Protein Kinase; SVG, Sterile Vegetative GrowthSVG; Osmotic stress; Cell wall integrity; Pathogenic fungus; MAPK phosphorylation; Candida albicans
Targeting apoptosis pathways in pancreatic cancer
Keywords: MAPK، پروتئین کیناز متیوژن فعال; Programmed cell death; Anti-cancer therapy; ChemoresistanceEGF, epidermal growth factor; ERK, extracellular signal related kinase; HDAC, histone deacetylase; HDI, HDAC inhibitor; IKK, IκBkinase; MAPK, mitogen activated protein kinase; miRNA, micro RNA; mT
JAK2-targeted anti-inflammatory effect of a resveratrol derivative 2,4-dihydroxy-N-(4-hydroxyphenyl)benzamide
Keywords: MAPK، پروتئین کیناز متیوژن فعال; PG, prostaglandin; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; TNF-α, tumor necrosis factor α; ERK, extracellular signal-related kinase; TLR, Toll-like receptors; MAPK, mitogen activated protein kinase; NF-κB, nuclear factor-κB; AP
Mucoid Pseudomonas aeruginosa caused by mucA mutations result in activation of TLR2 in addition to TLR5 in airway epithelial cells
Keywords: MAPK، پروتئین کیناز متیوژن فعال; AEC, airway epithelial cells; CF, cystic fibrosis; CFTR, CF transmembrane regulator; MAPK, mitogen activated protein kinase; PRR, pattern recognition receptor; PsaDM, P. aeruginosa diffusible material; SCFM, synthetic CF media; TLR, Toll-like receptorsPse
A novel dehydrin-like protein from Aspergillus fumigatus regulates freezing tolerance
Keywords: MAPK، پروتئین کیناز متیوژن فعال; AFP, anti-freeze protein; DTT, dithiothreitol; eGFP, enhanced green fluorescent protein; HCA, hydrophobic cluster analysis; HSP, heat shock protein; MAPK, mitogen activated protein kinase; UPR, unfolded protein responseFreeze–thaw injury; Water channel; A
Integrins in mammary development
Keywords: MAPK، پروتئین کیناز متیوژن فعال; BLG, β-lactoglobulin; ECM, extracellular matrix; FAK, focal adhesion kinase; ILK, integrin-linked kinase; JAK2, Janus-activated kinase 2; JNK, Jun NH2-terminal kinase; MAPK, mitogen activated protein kinase; MMTV, mouse mammary tumor virus; P130Cas, p130
Cyclosporin A and tacrolimus induce renal Erk1/2 pathway via ROS-induced and metalloproteinase-dependent EGF-receptor signaling
Keywords: MAPK، پروتئین کیناز متیوژن فعال; ADAM-17, a disintegrin and metalloproteinase 17; PPIase, peptidyl-prolyl cis/trans isomerase; CsA, cyclosporin A; ERK, extracellular signal-regulated kinase; MAPK, mitogen activated protein kinase; MC, mesangial cells; NAC, N-acetyl cysteine; ROS, reactiv
Transcriptomic profile of host response in mouse brain after exposure to plant toxin abrin
Keywords: MAPK، پروتئین کیناز متیوژن فعال; CNS, central nervous system; GSH, glutathione; PBS, phosphate buffered saline; qRT-PCR, quantitative real-time polymerase chain reaction; MAPK, mitogen activated protein kinase; KEGG, Kyoto Encyclopedia of Genes and Genomes; DAVID, Database for Annotation
Comparative proteomic analysis to dissect differences in signal transduction in activating TSH receptor mutations in the thyroid
Keywords: MAPK، پروتئین کیناز متیوژن فعال; PKA, protein kinase A; GEF(s), guanine nucleotide exchange factor(s); EPAC, exchange proteins activated by cAMP; MAPK, mitogen activated protein kinase; mTOR, mammalian target of rapamycin; 8-CPT, 8-CPT-2-O-Me-cAMPThyroid hormone stimulating receptor (TSH
Mechanical regulation of signaling pathways in bone
Keywords: MAPK، پروتئین کیناز متیوژن فعال; Akt, protein kinase B; MAPK, mitogen activated protein kinase; FAK, focal adhesion kinase; GTPase, guanine triphosphatase; MSC, mesenchymal stem cell; 1,25(OH)2D3, 1,25 dihydroxy vitamin D3; RANKL, receptor activator of NF kappa B ligand; mRNA, messenger
Pathogenesis of pre-eclampsia: marinobufagenin and angiogenic imbalance as biomarkers of the syndrome
Keywords: MAPK، پروتئین کیناز متیوژن فعال; preE, Preeclampsia; MBG, marinobufagenin; RBG, resibufogenin; IUGR, intrauterine growth restriction; DOCA, desoxycorticosterone acetate; MAPK, mitogen activated protein kinase; BBB, blood-brain barrier; CTB, cytotrophoblast; ECF, extracellular fluid; RLME
Phytoalexin transgenics in crop protection—Fairy tale with a happy end?
Keywords: MAPK، پروتئین کیناز متیوژن فعال; CHS, chalcone synthase; HR, hypersensitive response; IAA, indole-3-acetic acid; MAPK, mitogen activated protein kinase; PAL, phenylalanine ammonia-lyase; PR, pathogenesis related; PAMP, pathogen- associated molecular patterns; ROS, reactive oxygen species
Molecular cross-regulation between PPAR-γ and other signaling pathways: Implications for lung cancer therapy
Keywords: MAPK، پروتئین کیناز متیوژن فعال; EGFR, epidermal growth factor receptor; HDAC, histone deacetylases; IKK, iκB kinase; IL-1β, interleukin 1 β; MAPK, mitogen activated protein kinase; MMP, matrix metallo protease; NES, nuclear export signal; PGC1α, PPARγ coactivator-1; PGJ2, prostaglandin
Adaptive changes results in activation of alternate signaling pathways and resistance to aromatase inhibitor resistance
Keywords: MAPK، پروتئین کیناز متیوژن فعال; ER, estrogen receptor; Δ4A, androstenedione; E2, estradiol; HER-2, human epidermal growth factor receptor-2; MAPK, mitogen activated protein kinase; AIs, aromatase inhibitors; AEs, antiestrogens; TRZ, trastuzumab; Let, letrozoleAromatase inhibitors; Estro
TGF-β signals the formation of a unique NF1/Smad4-dependent transcription repressor-complex in human diploid fibroblasts
Keywords: MAPK، پروتئین کیناز متیوژن فعال; ANT, adenine nucleotide translocator; Go-1/Go-2, Go NF1-binding repressor elements 1 and 2; TGF-β, transforming growth factor-β; TGF-β RI, transforming growth factor-β type I receptor; MAPK, mitogen activated protein kinase; HGPRT, hypoxanthine–guanine ph
A non-coding transcript of nephronectin promotes osteoblast differentiation by modulating microRNA functions
Keywords: MAPK، پروتئین کیناز متیوژن فعال; 3′-UTR, 3′-untranslated region; miRNA, microRNA; AMEM, alpha modified eagle’s medium; FBS, fetal bovine serum; PAGE, polyacrylamide gel electrophoresis; ERK, extracellular signal related kinase; MAPK, mitogen activated protein kinase; EGFR, epidermal grow
Phosphorylation/dephosphorylation of human SULT4A1: Role of Erk1 and PP2A
Keywords: MAPK، پروتئین کیناز متیوژن فعال; SULT, cytosolic sulfotransferase; PP2A, protein phosphatase 2A; HA, hemagglutinin A; GST, glutathione s-transferase; MAPK, mitogen activated protein kinase; ERK, extracellular signal-regulated kinaseSulfotransferase; PP2A; ERK1; Phosphorylation
Mild stretch activates cPLA2 in alveolar type II epithelial cells independently through the MEK/ERK and PI3K pathways
Keywords: MAPK، پروتئین کیناز متیوژن فعال; cPLA2, cytosolic Phospholipase A2; MAPK, Mitogen Activated Protein Kinase; ERK1/2, Extracellular Signal-Regulated Kinases 1/2; PI3 kinase, phosphatidylinositol 3-kinase; AA, arachidonic acidMechanical stretch; A549 cells; Cytosolic PLA2; ERK1/2; PI3 kinas
Growth factor signaling enhances aromatase activity of breast cancer cells via post-transcriptional mechanisms
Keywords: MAPK، پروتئین کیناز متیوژن فعال; PI3K, phosphatidylinositol 3-kinase; Akt, protein kinase B; MAPK, mitogen activated protein kinase; COX2, cyclooxygenase 2; PGE2, prostaglandin E2; EP, PGE2 receptor; ER, estrogen receptor; EGF, epidermal growth factor; TGFα, transforming growth factor α;
Role of mitogen activated protein kinases in skin tumorigenicity of Patulin
Keywords: MAPK، پروتئین کیناز متیوژن فعال; PAT, Patulin; MAPK, mitogen activated protein kinase; ERK, Extracellular signal-related kinases; JNK, jun-amino terminal kinases; TPA, 12-tetradecanoyl phorbol myristate acetate; DMBA, dimethylbenzanthracene; DCFDA, 2′,7′-Dichlorofluorescin diacetateMycot