Keywords: ماوس Mdx; Duchenne muscular dystrophy; Translational biomarker; Titin; mdx mouse; Dmdmdx rat;
مقالات ISI ماوس Mdx (ترجمه نشده)
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Keywords: ماوس Mdx; mdx mouse; Associative learning; Executive functions; Working memory; Spatial learning; Hearing;
Keywords: ماوس Mdx; [125I]-αBGT; [125I]-α-bungarotoxin; ACh; acetylcholine; AChE; acetylcholinesterase; ANOVA; analysis of variance; ATR; atropine; CA1; cornus ammonis 1 of hippocampus; DAPC; dystrophin-associated glycoprotein complex; DHBE; dihydro-β-erythroidine; DMD; D
Expression patterns of regulatory RNAs, including lncRNAs and tRNAs, during postnatal growth of normal and dystrophic (mdx) mouse muscles, and their response to taurine treatment
Keywords: ماوس Mdx; Skeletal muscle; Post-natal growth; Non-coding RNAs; Mdx mouse; Muscular dystrophy; Taurine;
Effect of a long-term treatment with metformin in dystrophic mdx mice: A reconsideration of its potential clinical interest in Duchenne muscular dystrophy
Keywords: ماوس Mdx; DMD; Duchenne muscular dystrophy; DGC; dystrophin-associated glycoprotein complex; ECM; extracellular matrix; SIRT1; Sirtuin1; PGC-1α; peroxisome proliferator-activated receptor γ coactivator 1α; PPARγ; peroxisome proliferator-activated receptor γ; B
Reduced Myocardial Reserve in Young X-Linked Muscular Dystrophy Mice Diagnosed by Two-Dimensional Strain Analysis Combined with Stress Echocardiography
Keywords: ماوس Mdx; Duchenne muscular dystrophy cardiomyopathy; Myocardial reserve; Stress echocardiography; Strain; mdx mouse; ÎTpeak,max; Maximum time difference between times to peak systolic strain; 2D; Two-dimensional; CC; Cardiac cycle; C-Endo; Circumferential peak sy
Assessment of ventricular function in mouse models of muscular dystrophy: A comparison of MRI with conductance catheter
Keywords: ماوس Mdx; Cardiac MRI; Cardiac conductance catheter; cardiomyopathy; Sgcdâ/â mouse; Mdx mouse; Preclinical research; Outcome measures;
Opposing roles of miR-21 and miR-29 in the progression of fibrosis in Duchenne muscular dystrophy
Keywords: ماوس Mdx; α-SMA; α-smooth muscle actin; COL1A1; collagen type I alpha 1; COL3A1; collagen type III alpha 1; COL6A1; collagen type VI alpha 1; DMD; Duchenne muscle dystrophy; ECM; extracellular matrix; ERK; extracellular signal-regulated kinase; FBN1; fibrillin 1;
Low intensity training of mdx mice reduces carbonylation and increases expression levels of proteins involved in energy metabolism and muscle contraction
Keywords: ماوس Mdx; 2D-PAGE; two dimensional polyacrylamide gel electrophoresis; BN-PAGE; Blue Native polyacrylamide gel electrophoresis; Co-IP; coimmunoprecipitation; DMD; Duchenne muscular dystrophy; DNPH; 2,4-dinitrophenylhydrazine; IEF; isoelectric focusing; LIT; low int
Long-term administration of the TNF blocking drug Remicade (cV1q) to mdx mice reduces skeletal and cardiac muscle fibrosis, but negatively impacts cardiac function
Keywords: ماوس Mdx; Muscular dystrophy; Inflammation; mdx mouse; Treatment; Myostatin; AKT; Signaling;
Noninvasive in vivo assessment of muscle impairment in the mdx mouse model – A comparison of two common wire hanging methods with two different results
Keywords: ماوس Mdx; Duchenne muscular dystrophy; mdx mouse; Wire hanging test; Noninvasive function test; Muscle impairment
N-Acetylcysteine treatment of dystrophic mdx mice results in protein thiol modifications and inhibition of exercise induced myofibre necrosis
Keywords: ماوس Mdx; Duchenne Muscular Dystrophy; mdx Mouse; N-Acetylcysteine; Treadmill exercise; Oxidative stress; Protein thiol oxidation;
Identification of decorin derived peptides with a zinc dependent anti-myostatin activity
Keywords: ماوس Mdx; Decorin; Small leucine rich proteoglycans; Myostatin; Skeletal muscle; Muscular dystrophy; mdx mouse;
Animal Models of Duchenne Muscular Dystrophy, with Special Reference to the mdx Mouse
Keywords: ماوس Mdx; duchenne muscular dystrophy; mdx mouse; cardiomyopathy; animal models; MRI; cardiac catheter; standard operating procedures
A single 30Â min treadmill exercise session is suitable for 'proof-of concept studies' in adult mdx mice: A comparison of the early consequences of two different treadmill protocols
Keywords: ماوس Mdx; Mdx mouse; Treadmill exercise; Skeletal muscle damage; Myofibre necrosis; Creatine kinase; Inflammation; Oxidative stress;
Rescue of a dystrophin-like protein by exon skipping normalizes synaptic plasticity in the hippocampus of the mdx mouse
Keywords: ماوس Mdx; Dystrophin; Exon skipping; Gene therapy; Mdx mouse; Synaptic plasticity; Hippocampus; Inhibition; GABA receptor; AAV vector; Adult brain;
Reduced resting potentials in dystrophic (mdx) muscle fibers are secondary to NF-κB-dependent negative modulation of ouabain sensitive Na+-K+ pump activity
Keywords: ماوس Mdx; Duchenne muscular dystrophy; Mdx mouse; Na+-K+ ATPase pump; Resting membrane potential; Ouabain; NF-κB inhibitors; Pyrrolidine dithiocarbamate; Ursodeoxycholic acid;
Blockade of TNF in vivo using cV1q antibody reduces contractile dysfunction of skeletal muscle in response to eccentric exercise in dystrophic mdx and normal mice
Keywords: ماوس Mdx; Inflammation; Muscle damage; Isokinetic dynamometer; Duchenne muscular dystrophy; mdx mouse;
Serum matrix metalloproteinase-9 (MMP-9) as a biomarker for monitoring disease progression in Duchenne muscular dystrophy (DMD)
Keywords: ماوس Mdx; Duchenne muscular dystrophy; Matrix metalloproteinase-9; Tissue inhibitors of metalloproteinase-1; Osteopontin; mdx mouse;
Bone is functionally impaired in dystrophic mice but less so than skeletal muscle
Keywords: ماوس Mdx; Duchenne muscular dystrophy; Bone geometry; μCT; Bone strength; Mdx mouse;
Pre-clinical study of 21 approved drugs in the mdx mouse
Keywords: ماوس Mdx; Dystrophin; Duchenne muscular dystrophy; Nematode; mdx Mouse; Tricyclics; Antidepressants
A simple protocol for assessing inter-trial and inter-examiner reliability for two noninvasive measures of limb muscle strength
Keywords: ماوس Mdx; Muscular dystrophy; mdx mouse; Wire holding test; Escape test; Whole body tension; Muscle function; Noninvasive measures; Duchenne muscular dystrophy; Becker muscular dystrophy; Translational studies
Reduction of abnormal behavioral response to brief restraint by information from other mice in dystrophin-deficient mdx mice
Keywords: ماوس Mdx; Duchenne muscular dystrophy; mdx mouse; Behavior; Olfactory information; Attention
Excessive collagen accumulation in dystrophic (mdx) respiratory musculature is independent of enhanced activation of the NF-κB pathway
Keywords: ماوس Mdx; Duchenne muscular dystrophy; Mdx mouse; NF-κB; Fibrosis; TGF-β1; MMP-9; Collagen; Skeletal muscle; Triangularis sterni; Diaphragm
A 3 months mild functional test regime does not affect disease parameters in young mdx mice
Keywords: ماوس Mdx; Mdx mouse; Duchenne Muscular Dystrophy; Histopathology; Biomarkers; Functional tests;
Oxidative variables and antioxidant enzymes activities in the mdx mouse brain
Keywords: ماوس Mdx; mdx mouse; Brain; Oxidative variables
RhoA leads to up-regulation and relocalization of utrophin in muscle fibers
Keywords: ماوس Mdx; DGC; dystrophin glycoprotein complex; GFP; green fluorescent protein; NMJ; neuromuscular junction; TA; Tibialis anterior; Utrophin up-regulation; Duchenne muscular dystrophy; Dystrophin; RhoA GTPase; mdx mouse;
Treatment with inhibitors of the NF-κB pathway improves whole body tension development in the mdx mouse
Keywords: ماوس Mdx; Muscular dystrophy; Mdx mouse; NF-κB; Ursodeoxycholic acid; Pyrollidine dithiocarbamate; Muscle function; Whole body tension
Nerve growth factor and its receptors TrkA and p75 are upregulated in the brain of mdx dystrophic mouse
Keywords: ماوس Mdx; angiogenesis; blood–brain barrier; mdx mouse; MMPs; NGF; VEGFAQP4, aquaporin-4; BB, blocking buffer; BBB, blood–brain barrier; BSA, bovine serum albumin; CNS, central nervous system; CSF, cerebrospinal fluid; DAP, dystrophin-associated protein; DMD, Duche
Increases in nuclear p65 activation in dystrophic skeletal muscle are secondary to increases in the cellular expression of p65 and are not solely produced by increases in IκB-α kinase activity
Keywords: ماوس Mdx; Duchenne muscular dystrophy; Becker muscular dystrophy; mdx mouse; NF-κB; Diaphragm; Respiratory musculature; Limb musculature; Akt; Cell signaling
Regions downstream from the WW domain of dystrophin are important for binding to postsynaptic densities in the brain
Keywords: ماوس Mdx; mdx mouse; Hippocampus; Neuron; Primary culture; Adenovirus vector; Minidystrophin
Mdx respiratory impairment following fibrosis of the diaphragm
Keywords: ماوس Mdx; Duchenne muscular dystrophy; Mdx mouse; Respiratory function; Whole-body plethysmography; Gene therapy;
GABAergic miniature spontaneous activity is increased in the CA1 hippocampal region of dystrophic mdx mice
Keywords: ماوس Mdx; Duchenne muscular dystrophy; Dystrophin; GABAaR; CA1; IPSC; Interneuron; Electrophysiology; mdx mouse
Strong induction of the Tis11B gene in myogenic differentiation
Keywords: ماوس Mdx; TIS11B; Myogenesis; p38 MAPK; mdx mouse
In vivo delivery of naked antisense oligos in aged mdx mice: Analysis of dystrophin restoration in skeletal and cardiac muscle
Keywords: ماوس Mdx; Exon skipping; Antisense oligonucleotides; mdx mouse; Force measurement; Cardiac muscle
Reduced muscle necrosis and long-term benefits in dystrophic mdx mice after cV1q (blockade of TNF) treatment
Keywords: ماوس Mdx; DMD; Mdx mouse; TNF; Myofibre necrosis; Voluntary exercise
Transient receptor potential cation channels in normal and dystrophic mdx muscle
Keywords: ماوس Mdx; Duchenne muscular dystrophy; mdx mouse; Calcium influx; TRP channels; TRPC3; TRPC6; TRPV4; TRPM7; Sarcolemma;
Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy
Keywords: ماوس Mdx; Mdx mouse; Muscular dystrophy; Standard operating procedures; Biological variation; Muscle function; Pre-clinical trials
Morphological changes in the trigemino-rubral pathway in dystrophic (mdx) mice
Keywords: ماوس Mdx; Dystrophin; Duchenne muscle disease; mdx mouse; Red nucleus; Trigeminal sensory nuclear complex; Fluorogold;
Cytoplasmic γ-actin expression in diverse animal models of muscular dystrophy
Keywords: ماوس Mdx; Duchenne muscular dystrophy; mdx Mouse; GRMD dog; γ-Actin; Sarcoglycan; α-Dystrobrevin; α7 Integrin; Utrophin;
Strength and corticosteroid responsiveness of mdx mice is unchanged by RAG2 gene knockout
Keywords: ماوس Mdx; BW; body weight; CK; creatine kinase; FGS; forelimb grip strength; GC; glucocorticoid; RAG2; recombinase activating gene 2; SCID; severe combined immune deficiency; mdx mouse; Prednisolone; RAG2 knockout; Strength; Fatigue; Voluntary wheel running; T-cell
Duchenne muscular dystrophy: Focus on pharmaceutical and nutritional interventions
Keywords: ماوس Mdx; Duchenne muscular dystrophy; Mdx mouse; Pharmaceuticals; Nutritional supplements; Therapy;
Postnatal overexpression of the CT GalNAc transferase inhibits muscular dystrophy in mdx mice without altering muscle growth or neuromuscular development: Evidence for a utrophin-independent mechanism
Keywords: ماوس Mdx; Dystroglycan; Utrophin; Neuromuscular junction; Glycosylation; Muscle; Duchenne muscular dystrophy; mdx mouse
Bone marrow transplantation improves outcome in a mouse model of congenital muscular dystrophy
Keywords: ماوس Mdx; BMT, bone marrow transplantation; DMD, Duchenne muscular dystrophy; MDC1A, congenital muscular dystrophy type 1A; SpO2, arterial hemoglobin saturationBone marrow transplantation; Muscular dystrophy; mdx mouse; dy mouse; Laminin α2; Basal lamina
Overactivity of exercise-sensitive cation channels and their impaired modulation by IGF-1 in mdx native muscle fibers: Beneficial effect of pentoxifylline
Keywords: ماوس Mdx; In vivo exercise; Muscular dystrophy; mdx mouse; Patch-clamp recordings; Voltage-insensitive cation channels; IGF-1 and cAMP modulation; Pentoxifylline; Histology
S-myotrophin promotes the hypertrophy of skeletal muscle of mice in vivo
Keywords: ماوس Mdx; Muscle hypertrophy; S-myotrophin; Normal mouse; mdx mouse; ScN mouse; Dystrophin; Laminin;
Streptomycin reduces stretch-induced membrane permeability in muscles from mdx mice
Keywords: ماوس Mdx; mdx mouse; Stretch-activated channels; Membrane permeability;
Variability and failure of neurotransmission in the diaphragm of mdx mice
Keywords: ماوس Mdx; Dystrophin; mdx Mouse; Neurotransmission failure; Neuromuscular junctionAChRs, Acetylcholine receptors; DMD, duchenne muscular dystrophy; EPP, endplate potential; MEPP, miniature endplate potential; NMJ, neuromuscular junction; Lo, optimal muscle length
Poloxamer 188 failed to prevent exercise-induced membrane breakdown in mdx skeletal muscle fibers
Keywords: ماوس Mdx; mdx mouse; Poloxamer 188; Sarcolemma; Dystrophin-deficient; Exercise;
Generation of skeletal muscle from transplanted embryonic stem cells in dystrophic mice
Keywords: ماوس Mdx; Embryonic stem cells; Muscle; Dystrophy; Transplantation; mdx mouse;