Keywords: miRNAs، microRNAs; BDNF, brain-derived neurotrophic factor; Dnmt-1, DNA methyltransferase 1; miRNAs, microRNAs; mPFC, medial prefrontal cortex; piRNA, Piwi interacting RNAstransgenerational inheritance; epigenetics; cocaine; BDNF; prefrontal cortex
مقالات ISI miRNAs، microRNAs (ترجمه نشده)
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Keywords: miRNAs، microRNAs; miRNAs, MicroRNAs; BPH, Benign prostatic hyperplasis; PCa, Prostate cancer; PSA, Prostate specific antigen; AR, Androgen receptor; PRDX1, Peroxiredoxin 1; q RT-PCR, Quantitative real time PCR; M, Methylated; U, UnmethylatedProstate cancer; miRNAs; miR-510
Comprehensive review of genetic association studies and meta-analysis on miRNA polymorphisms and rheumatoid arthritis and systemic lupus erythematosus susceptibility
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; SNPs, single nucleotide polymorphisms; ACR, American College of Rheumatology; OR, odds ratio; 95% CI, 95% confidence interval; HWE, Hardy–Weinberg equilibriumMicroRNAs; Polymo
Roles of miR-278-3p in IBP2 regulation and Bombyx mori cytoplasmic polyhedrosis virus replication
Keywords: miRNAs، microRNAs; BmCPV, Bombyx mori cytoplasmic polyhedrosis virus; miRNAs, microRNAs; IBP, insulin-related peptide binding protein; B. mori, Bombyx mori; qRT-PCR, quantitative real-time PCR; IGFBP7, insulin-like growth-factor binding protein 7; IB, a single insulin bindi
MicroRNA-29a contributes to drug-resistance of breast cancer cells to adriamycin through PTEN/AKT/GSK3β signaling pathway
Keywords: miRNAs، microRNAs; ADR, adriamycin; miRNAs, microRNAs; IGF-1R, insulin-like growth factor-1 receptor; GSK3β, Glycogen Synthase Kinase 3β; PTEN, phosphatase and tensin homolog deleted on chromosome 10; PI3K, phosphatidylinositol 3-kinase; IC50, the inhibitory concentration t
miR-195 inhibits tumor growth and angiogenesis through modulating IRS1 in breast cancer
Keywords: miRNAs، microRNAs; miRNAs, MicroRNAs; BC, breast cancer; VEGFA, vascular endothelial growth factor a; IRS1, Insulin receptor substrate 1; HIPAA, Health Insurance Portability and Accountability Act; DMEM, Dulbecco’s Modified Eagle Medium; FBS, fetal bovine serum; MEM, Minimu
Hypoxia-regulated lncRNAs in cancer
Keywords: miRNAs، microRNAs; lncRNAs, long noncoding RNAs; miRNAs, microRNAs; mRNAs, messenger RNAs; siRNA, small interfering RNA; HIF-1, hypoxia-inducible factor-1; linc-RoR, long intergenic noncoding RNA, regulator of reprogramming; NEAT1, Nuclear Enriched Abundant Transcript 1; UC
MicroRNA-506-3p regulates neural stem cell proliferation and differentiation through targeting TCF3
Keywords: miRNAs، microRNAs; NSCs, neural stem cells; miRNAs, microRNAs; siRNA, interfering RNA; ESC, embryonic stem cell; HEK, human embryonic kidney; GFAP, glial fibrillary acidic protein; Tuj1, Neuronal Class III β-TubulinNeural stem cell; TCF3; MicroRNA-506-3p
miR-125b inhibits keratinocyte proliferation and promotes keratinocyte apoptosis in oral lichen planus by targeting MMP-2 expression through PI3 K/Akt/mTOR pathway
Keywords: miRNAs، microRNAs; OLP, oral lichen planus; LPS, lipopolysaccharide; miRNAs, microRNAs; qRT-PCR, quantitative real-time PCR; . UTR, un-translated region; MMPs, matrix metalloproteinases; OSCC, oral squamous cell carcinoma; FBS, fetal bovine serum; CCK-8, cell counting kit-8
Integrative proteomic and microRNA analysis of the priming phase during rat liver regeneration
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; 3′UTRs, 3′ untranslated regions; PH, partial hepatectomy; LR, liver regeneration; iTRAQ, isobaric tags for relative and absolute quantitation; IPA, ingenuity pathway analysis; SCX, strong cation exchange; HCC, hepatocellular carcinoma;
miR-125b targets DNMT3b and mediates p53 DNA methylation involving in the vascular smooth muscle cells proliferation induced by homocysteine
Keywords: miRNAs، microRNAs; VSMCs, Vascular Smooth Muscle Cells; AS, atherosclerosis; Hcy, homocysteine; HHcy, Hyperhomocysteinemia; DNMT3b, DNA (cytosine-5)-methyltransferase 3b; nMS-PCR, nested methylation-specific-PCR; UTR, untranslated region; miRNAs, microRNAs; mfe, minimum fre
A novel framework for inferring condition-specific TF and miRNA co-regulation of protein–protein interactions
Keywords: miRNAs، microRNAs; TF, transcription factor; miRNAs, microRNAs; PPI, protein–protein interaction; mRNA, messenger RNA; FFL, feed-forward loop; FBL, feedback loop; CoRePPI, Condition-specific Regulation of PPIs; TCGA, The Cancer Genome Atlas; BLCA, bladder urothelial carcino
miR-187-3p inhibits the metastasis and epithelial–mesenchymal transition of hepatocellular carcinoma by targeting S100A4
Keywords: miRNAs، microRNAs; miR-187-3p; S100A4; Hepatocellular carcinoma; Metastasis; EMTHCC, hepatocellular carcinoma; EMT, epithelial–mesenchymal transition; miRNAs, microRNAs; H&E, hematoxylin and eosin; PVTT, portal vein tumor thrombus; qRT-PCR, real-time quantitative reverse tr
MicroRNA expression is altered in lateral septum across reproductive stages
Keywords: miRNAs، microRNAs; ANOVA, analysis of variance; ATFD, Animal Transcription Factor Database; CNS, central nervous system; LS, lateral septum; miRNAs, microRNAs; mPFC, edial prefrontal cortex; MPOA, medial preoptic area; MSET, Modular Single-set Enrichment Test; NAC, nucleus
Effects of microRNA-346 on epithelial–mesenchymal transition in mouse podocytes
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; 3′-UTR, 3′-untranslated region; GSK-3β, glycogen synthase kinase-3β; EMT, epithelial–mesenchymal transition; Invitrogen, Lipofectamine 2000; SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis; PVDF, polyvinylidene fluor
Computational analysis of miRNA-target community network reveals cross talk among different metabolisms
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; GRN, Gene Regulatory Network; FDR, false discovery rateMicroRNAs; EST; MiRNA community; Nitrogen metabolism
miR-99b suppresses IGF-1R expression and contributes to inhibition of cell proliferation in human epidermal keratinocytes
Keywords: miRNAs، microRNAs; CA, condyloma acuminatum; HPV, human papillomavirus; miRNAs, microRNAs; IGF-1R, insulin-like growth factor-1 receptor; qRT-PCR, quantitative real-time PCR analysis; p-AKT, phosphorylated AKT1Condyloma acuminatum; miR-99b; IGF-1R; PI3K-AKT; Proliferation
Haploinsufficiency of the miR-873/miR-876 microRNA cluster is associated with craniofacial abnormalities
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; Lingo2, leucine rich repeat and Ig domain containing 2; aCGH, array comparative genomic hybridization; DGV, Database of Genomic Variants; Hh, HedgehogCraniofacial; Developmental defect; Haploinsufficiency; Hedgehog; miR-873; miR-876
MicroRNA expression profiling and functional annotation analysis of their targets associated with the malignant transformation of oral leukoplakia
Keywords: miRNAs، microRNAs; FGF3, fibroblast growth factor 3; GEO, Gene Expression Omnibus; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; miRNAs, microRNAs; mtOLK, malignant transformed oral leukoplakia; ncRNA, non-coding RNA; OLK, oral leukoplakia; OSCC, oral sq
Downregulation of miR-363 increases drug resistance in cisplatin-treated HepG2 by dysregulating Mcl-1
Keywords: miRNAs، microRNAs; HCC, hepatocellular carcinoma; HepG2-R, cisplatin-resistant HepG2; 3′-UTR, 3′-Untranslated Regions; MiRNAs, microRNAs; FBS, fetal bovine serum; RT, reverse transcription; NCO, oligonucleotide; MTT, (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromid
In silico identification, characterization and expression analysis of miRNAs in Cannabis sativa L.
Keywords: miRNAs، microRNAs; ESTs, Expressed Sequence Tags; TSA, transcribed sequence assemblies; MiRNAs, MicroRNAs; DCL, dicer like enzyme; Nt, nucleotide; Pre-miRNAs, precursor microRNAs; BLAST, basic local alignment search tool; GO, gene ontologyComputational; Conserved; Expressio
Global correlation analysis for microRNA and gene expression profiles in human obesity
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; GEO, gene expression omnibus; DEMs, differentially expressed miRNAs; DEGs, differentially expressed genes; RMA, Robust multiarray average; GO, gene ontology; DAVID, The Database for Annotation, Visualization and Integrated Discovery; MT
MicroRNA-138 regulates the balance of Th1/Th2 via targeting RUNX3 in psoriasis
Keywords: miRNAs، microRNAs; Th, T helper; IL, interleukin; RUNX3, Runt-related transcription factor 3; microRNA-138, miR-138; miRNAs, MicroRNAs; MERs, miRNA recognition elements; 3′-UTR3′, untranslated region; mRNAs, messenger RNAs; PASI, psoriasis area severity indexPsoriasis; RUNX
MicroRNA-495 regulates the proliferation and apoptosis of human umbilical vein endothelial cells by targeting chemokine CCL2
Keywords: miRNAs، microRNAs; CAD, coronary artery disease; CCK8, cell counting kit 8; Ct, threshold cycle; ECs, endothelial cells; HUVECs, human umbilical vein endothelial cells; miRNAs, microRNAs; NC, negative control; qRT-PCR, quantitative RT-PCR; 3’ UTR, 3’ untranslated regionAthe
MicroRNAs: New players in intervertebral disc degeneration
Keywords: miRNAs، microRNAs; IVD, intervertebral disc; NP, nucleus pulposus; AF, annulus fibrosus; CEPs, cartilaginous endplates; IDD, intervertebral disc degeneration; ECM, extracellular matrix; miRNAs, microRNAs; RNA pol, RNA polymerase; DGCR8, DiGeorge syndrome critical gene 8; Ex
Effects of simulated microgravity on microRNA and mRNA expression profile of rat soleus
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; TS, tail suspension; SMG, simulated microgravity; IGF-1, insulin-like growth factor 1; PI3K/Akt, phosphatidylinositol 3-kinases/protein kinase B; PTEN, phosphatase and tensin homology deleted on chromosome 10; SFRP2, Secreted frizzled-r
Integrative computational mRNA–miRNA interaction analyses of the autoimmune-deregulated miRNAs and well-known Th17 differentiation regulators: An attempt to discover new potential miRNAs involved in Th17 differentiation
Keywords: miRNAs، microRNAs; IBD, inflammatory bowel disease; miRNAs, microRNAs; MS, multiple sclerosis; PBMCs, peripheral blood mononuclear cells; PS, prediction score; RA, rheumatoid artists; RAR, retinoic acid receptor; RRMS, relapsing-remitting MS; RXR, retinoid X receptor; SLE,
miR-375 regulates the canonical Wnt pathway through FZD8 silencing in arthritis synovial fibroblasts
Keywords: miRNAs، microRNAs; Rheumatoid arthritis; Adjuvant-induced arthritis; miR-375; Canonical Wnt signaling; Frizzled 8RA, Rheumatoid arthritis; FLS, fibroblast-like synoviocytes; miRNAs, microRNAs; FZD8, Frizzled 8; RANKL, receptor activator of nuclear factor-kappa B ligand; WIS
MicroRNA-663 activates the canonical Wnt signaling through the adenomatous polyposis coli suppression
Keywords: miRNAs، microRNAs; RA, rheumatoid arthritis; FLS, fibroblast-like synoviocytes; miRNAs, microRNAs; APC, adenomatous polyposis coli; 3′UTR, 3′-untranslated region; miRISC, miRNA-induced silencing complex; SDF-1, stromal cell derived factor 1; VCAM-1, vascular cell adhesion m
CCL5 promotes vascular endothelial growth factor expression and induces angiogenesis by down-regulating miR-199a in human chondrosarcoma cells
Keywords: miRNAs، microRNAs; VEGF, vascular endothelial growth factor; miRNAs, microRNAs; MMP-3, matrix metalloproteinase-3; CM, conditioned medium; JJ012, human chondrosarcoma cell line; EPCs, endothelial progenitor cells; PBMCs, peripheral blood mononuclear cells; CAM, chorioallant
MiR-205 and miR-218 expression is associated with carboplatin chemoresistance and regulation of apoptosis via Mcl-1 and Survivin in lung cancer cells
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; 3′-UTRs, 3′-untranslated regions; BCL-2, B-cell lymphoma 2; ERCC1, excision repair cross-complementation group 1; LRP, resistance-related protein; MDR1, multidrug resistance protein 1; MRP, multidrug resistance associated protein 1; GST
MicroRNA-21/PTEN/Akt axis in the fibrogenesis of biliary atresia
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; miR-21, MicroRNA-21; BA, biliary atresia; PTEN, phosphatase and tensin homolog deleted on chromosome ten; a-SMA, a-smooth muscle actin; IHC, immunohistochemistry; HSC, hepatic stellate cell; MEM, minimum essential medium; H&E, hematoxyl
Down-regulation of miR-199b associated with imatinib drug resistance in 9q34.1 deleted BCR/ABL positive CML patients
Keywords: miRNAs، microRNAs; CML, chronic myeloid leukemia; miRNAs, microRNAs; FISH, fluorescence in-situ hybridization; BAC, bacterial artificial chromosomes; BCR, breakpoint cluster region; ABL, Abelson; PCR, polymerase chain reaction; RT-PCR, real time PCR; REST, Relative Expressi
Tumor-stromal cross talk: direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes
Keywords: miRNAs، microRNAs; FACS, fluorescence-activated cell sorting; FBS, fetal bovine serum; miRNAs, microRNAs; nM, nanomolars; nm, nanometers; ng, nanograms; OB, osteoblasts; OS, osteosarcoma; TnTs, Tunneling nanotubes
MiR-1 targets PIK3CA and inhibits tumorigenic properties of A549 cells
Keywords: miRNAs، microRNAs; Non-small cell lung cancer; MicroRNA; miR-1; PIK3CA; A549; Gene therapyMiR-1, MicroRNA-1; NSCLC, Non-small cell lung cancer; PIK3CA, Phosphoinositide-3-kinase catalytic subunit alpha; 3′UTR, 3′ untranslated region; miRNAs, MicroRNAs; CCK-8, Cell Counting
MicroRNA expression in the aging mouse thymus
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; IPA, Ingenuity Pathway Analysis; RISC, RNA-induced silencing complex; IGF1, insulin-like growth factor-1; FasL, Fas ligand (TNF superfamily, member 6); BCL-2, B cell lymphoma/leukemia-2; Mcl-1, myeloid cell leukemia-1; MMP9, matrix meta
Long noncoding RNAs: Novel insights into hepatocelluar carcinoma
Keywords: miRNAs، microRNAs; Long noncoding RNAs; Hepatocellular carcinoma (HCC); Function; Therapeutic targetslncRNAs, long noncoding RNAs; HCC, hepatocellular carcinoma; ncRNAs, non-coding RNAs; miRNAs, microRNAs; siRNAs, small interfering RNAs; piRNAs, PIWI-interacting RNAs; DDIT4
Circulating microRNA profiles altered in mice after 28 d exposure to perfluorooctanoic acid
Keywords: miRNAs، microRNAs; PFASs, perfluoroalkyl and polyfluoroalkyl substances; PFOA, perfluorooctanoic acid; PFOS, perfluorooctane sulfonate; miRNAs, microRNAs; PPAR, peroxisome proliferator activated receptor; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP,
MicroRNA-21 is a unique signature associated with coronary plaque instability in humans by regulating matrix metalloproteinase-9 via reversion-inducing cysteine-rich protein with Kazal motifs
Keywords: miRNAs، microRNAs; MMP, matrix metalloproteinase; miRNAs, microRNAs; 3′-UTR, 3′-untranslated region; RECK, reversion-inducing cysteine-rich protein with Kazal motifs; ECM, extracellular matrix; CCTA, coronary computed tomographic angiography; CACS, coronary artery calcium s
Identification of 23 novel conserved microRNAs in three rice cultivars
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; qPCR, quantitative real-time polymerase chain reaction; sRNA, small RNA; siRNAs, short interfering RNAs; pri-miRNA, primary RNA precursors; RDRP, RNA-dependent RNA polymerase; PAGE, polyacrylamide gel electrophoresis; CT, threshold cycl
MicroRNA-17/20a inhibits glucocorticoid-induced osteoclast differentiation and function through targeting RANKL expression in osteoblast cells
Keywords: miRNAs، microRNAs; GCs, Glucocorticoids; RA, Rheumatoid arthritis; GIO, GC-induced osteoporosis; RANKL, Receptor activator of nuclear factor B ligand; M-CSF, Macrophage-colony stimulating factor; OPG, Osteoprotegerin; miRNAs, MicroRNAs; 3′-UTR, 3′-untranslational region; α-
MiR-199a-3p promotes gastric cancer progression by targeting ZHX1
Keywords: miRNAs، microRNAs; GC, gastric cancer; MiRNAs, microRNAs; ZHX1, zinc fingers and homeoboxes 1; UTR, untranslated region; HCC, hepatocellular carcinomaGastric cancer; MiR-199a-3p; Proliferation; Apoptosis; ZHX1
Diagnostic and prognostic value of circulating miR-21 for cancer: A systematic review and meta-analysis
Keywords: miRNAs، microRNAs; miRNAs, MicroRNAs; HRs, hazard ratios; LRP, positive likelihood ratio; LRN, negative likelihood ratio; DOR, diagnostic odd ratio; OS, overall survival; QUADAS, Quality Assessment of Diagnostic Accuracy Studies; tp, true-positive; fp, false-positive; fn, f
The ways of action of long non-coding RNAs in cytoplasm and nucleus
Keywords: miRNAs، microRNAs; siRNA, small interfering RNA; miRNAs, microRNAs; lncRNAs, long non-coding RNAs; rRNAs, ribosomal RNAs; tRNAs, transfer RNAs; H3K4me3, trimethylation of lysine4 of histone H3; H3K36me3, trimethylation of lysine36 of histone H3; ORFs, open reading frames; U
MiR-98 is involved in rat embryo implantation by targeting Bcl-xl
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; Bcl-xl, B-cell lymphoma-extra large; 3′-UTR, 3′-untranslated region; PFA, paraformaldehyde; BCIP, 5-bromo-4-chloro-3-indolyl phosphate; NBT, p-nitroblue tetrazolium chloride; DIG, digoxigenin; ESCs, endometrial stromal cells; FITC, fluo
miR-29b suppresses proliferation, migration, and invasion of tongue squamous cell carcinoma through PTEN–AKT signaling pathway by targeting Sp1
Keywords: miRNAs، microRNAs; TSCC, tongue squamous cell carcinoma; Sp1, specificity protein 1; 3′ UTR, 3′ untranslated region; miRNAs, MicroRNAs; PTEN, phosphatase and tensin homolog; PI3K, phosphatidylinositol-3-kinase; DNMT3A/3B, DNA methyltransferase 3A/3B; HOK, human oral keratin
MiR-185 is involved in human breast carcinogenesis by targeting Vegfa
Keywords: miRNAs، microRNAs; miRNAs, MicroRNAs; Vegfa, vascular endothelial growth factor a; 3′-UTR, 3′-untranslated region; DMEM, Dulbecco’s Modified Eagle Medium; FBS, fetal bovine serum; qRT-PCR, quantitative reverse-transcriptase polymerase chain reaction; Gapdh, glyceraldehyde-3
Dynamic expression of microRNAs in M2b polarized macrophages associated with systemic lupus erythematosus
Keywords: miRNAs، microRNAs; SLE, systemic lupus erythematosus; ALD-DNA, activated lymphocyte-derived DNA; UnALD-DNA, unactivated lymphocyte-derived DNA; BMDMs, murine bone marrow derived macrophages; miRNAs, microRNAs; PBMCs, peripheral blood mononuclear cells; FACS, fluorescence-ac
MiR-125a TNF receptor-associated factor 6 to inhibit osteoclastogenesis
Keywords: miRNAs، microRNAs; miRNAs, microRNAs; PBMCs, peripheral blood mononuclear cells; RANKL, nuclear factor-κB ligand; M-CSF, macrophage colony stimulating factor; OPG, osteoprotegerin; M-CSFR, macrophage colony stimulating factor receptor; NFI-A, nuclear factor I-A; MMP2, metal
MiR-27 orchestrates the transcriptional regulation of brown adipogenesis
Keywords: miRNAs، microRNAs; WAT, White adipose tissue; SAT, Subcutaneous adipose tissue; VAT, Visceral adipose tissue; BAT, Brown adipose tissue; miRNAs, microRNAs; Ucp1, Uncoupling protein 1; Myf5, Myogenic factor 5; Prdm16, PRDI-BF1-RIZ1 (PR) domain containing 16; Pparα and γ, Per