Keywords: میتوفوسین 2; Connexin-43; Heart; IFM; Methods; Mitochondria isolation; Mitofusin; Nagarse; SSM; Subtilisin BPN'; ADP; adenosine diphosphate; ATP5A; ATP synthase subunit alpha; BNIP3; bcl-2/adenovirus E1B 19Â kDa protein-interacting protein 3; COX4; cytochrome c oxidas
مقالات ISI میتوفوسین 2 (ترجمه نشده)
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Keywords: میتوفوسین 2; WT; wild-type; KO; knockout; tau-/-; homozygous tau KO; mPTP; Mitochondrial permeability transition pore; AD; Alzheimer's disease; GR; Glucocorticoid Receptor; HO; heme oxygenase; GCS; γ-glutamine cysteine synthase; ROS; reactive oxygen species; Mfn1; Mi
Keywords: میتوفوسین 2; AIF; apoptosis-inducing factor; ASL; argininosuccinate lyase; ASS; argininosuccinate synthetase; AST; aspartate aminotransferase; BER; base excision repair; cGC; cyclic guanylyl cyclase; CNS; central nervous system; DRP-1; dynamin-related protein 1; EAE;
Keywords: میتوفوسین 2; Atherosclerosis; Cardiovascular diseases; Cell cycle; Proliferation; Pulmonary hypertension; Restenosis; Signaling pathway; Vascular smooth muscle cells; ACE; angiotensin converting enzyme; aFGF; acidic FGF; Ang II; angiotensin II; AP-1; activating protei
Keywords: میتوفوسین 2; Resveratrol; Mitochondria; Fusion; Mitofusin 2; Cell proliferation;
Keywords: میتوفوسین 2; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; BNIP3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; CHOP; C/EBP homologous protein; DRP1; dynamin-related protein 1; FIS1; fission protein 1; GRP78; 78Â kDa glucose-regulat
Keywords: میتوفوسین 2; ALCAR; Acetyl-l-carnitine; mtDNA; mitochondrial DNA; nDNA; nuclear DNA; CS; citrate synthase; PGC-1α; peroxisome proliferator-activated receptor γ [PPARγ] coactivator-1α; PGC-1β; peroxisome proliferator-activated receptor γ [PPARγ] coactivator-1 β
Keywords: میتوفوسین 2; Calcium (Ca2+); Mitochondria; Endoplasmic reticulum (ER); Inter-organelle contacts; ER-mitochondria tethering; Mitochondria-Associated Membranes (MAMs); Mitofusin 2;
Keywords: میتوفوسین 2; Cardiomyocyte apoptosis; Doxorubicin; Mitofusin 2; Mitochondrial reactive oxygen species;
Keywords: میتوفوسین 2; ATP; adenosine triphosphate; Ca2+; Â calcium; CamK; calmodulin-dependent kinase; ChREBP; carbohydrate response element binding protein; CypD; cylophilin D; DGAT2; diacylglycerol acyltransferase 2; ER; endoplasmic reticulum; FOXO1; Forkhead box O1; G6P; gl
Keywords: میتوفوسین 2; Erigeron breviscapus; Breviscapine; Ischemia reperfusion; Liver; Mitofusin 2
Keywords: میتوفوسین 2; Glycosaminoglycans; Weight loss; Fat loss; White adipose tissue; Oxidative metabolism; B2m; beta-2 microglobulin; BAT; brown adipose tissue; CCK; cholecystokinin; Cox5a; cytochrome c oxidase subunit Va; Cpt1a; carnitine palmitoyltransferase 1a (liver isof
Keywords: میتوفوسین 2; Akt; Protein kinase B; CHD; Coronary heart disease; Cx; Connexin; Drp-1; Dynamin related protein 1; EF; Ejection fraction; GAPDH; Glyceraldehyde 3-phosphate dehydrogenase; HSP60; Heat shock protein 60; JC-1; Tetraethylbenzimidazolylcarbocyanine iodide; LV
Keywords: میتوفوسین 2; Mitochondrial dynamics; Mitofusin 2; Bioenergetics; Coenzyme Q; Mevalonate pathway;
Keywords: میتوفوسین 2; AMPK; AMP-activated protein kinase; ATG; autophagy-related; CL; cardiolipin; EM; electron microscopy; EMC; ER membrane protein complex; ER; endoplasmic reticulum; ERMES; ER-mitochondria encounter structure; FFAT; two phenylalanines in an acid tract; HOPS;
Keywords: میتوفوسین 2; ATP synthesis; Reactive oxygen species; Mitofusin 2; Superoxide dismutase 2
Keywords: میتوفوسین 2; Mitofusin 2; Hypothalamus; Insulin resistance; Endoplasmic reticulum stress
Keywords: میتوفوسین 2; CNS; central nervous system; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; Ad; adenovirus; GFP; green fluorescent protein; EdU; 5-Ethynyl-2â²-deoxyuridine; GFAP; glial fibrillary acidic protein; PCNA; proliferating cell nuclear antig
Keywords: میتوفوسین 2; AICAR; 5â²aminoimidazole-4-carboxyamide-ribonucleoside; AD; Alzheimer's disease; ATF-2; activating transcription factor-2; AMPK; AMP-activated protein kinase; Bnip3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BnipL/Nix; BCL2/adenovirus E1B 19Â
Keywords: میتوفوسین 2; AKAP1; A kinase anchoring protein 1; Endo B1; endophilin B1; ER; endoplasmic reticulum; GDAP1; ganglioside-induced differentiation-associated protein 1; GED; GTPase effector domain; GFP; green fluorescent protein; KO; knockout; LRRK2; leucine-rich repeat
Different mitochondrial fragmentation after irradiation with X-rays and carbon ions in HeLa cells and its influence on cellular apoptosis
Keywords: میتوفوسین 2; Mitochondrial dynamics; Different quality radiations; Release of cytochrome c; Apoptosis; Radiosensitivity; LET; linear energy transfer; RBE; relative biological effectiveness; Mfn1; mitofusin1; Mfn2; mitofusin 2; OPA1; optic atrophy 1; Drp1; Dynamin-rela
Inhibition of ERK-Drp1 signaling and mitochondria fragmentation alleviates IGF-IIR-induced mitochondria dysfunction during heart failure
Keywords: میتوفوسین 2; AAV; adenovirus-associated virus; ANP; atrial natriuretic protein; ANG II; angiotensin II; BNP; brain natriuretic protein; Drp1; dynamin-related protein 1; ERK; extracellular signal-regulated kinase; IGF-II; insulin-like growth factor II; IGF-IIR; insulin
A novel homozygous MFN2 mutation associated with severe and atypical CMT2 phenotype
Keywords: میتوفوسین 2; Charcot-Marie-Tooth; CMT2; Mitofusin 2; MFN2; Neuropathy; Homozygous mutation; CMT; Charcot-Marie-Tooth disease; CMT2A; Charcot-Marie-Tooth type 2A; MFN2; mitofusin 2; NCV; nerve conduction velocity; EMG; electromyography; CMAP; compound motor action pote
TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics
Keywords: میتوفوسین 2; APP; amyloid precursor protein; VDAC1; voltage dependent anion channel 1; TDP-43; TAR DNA binding protein of 43â¯kDa; PSEN1/PS1; presenilin 1; AD; Alzheimer disease; hnRNP; heterogeneous nuclear ribonucleoprotein; ALS; amyotrophic lateral sclerosis; MND;
Highlighting the endoplasmic reticulum-mitochondria connection: Focus on Mitofusin 2
Keywords: میتوفوسین 2; Endoplasmic reticulum-mitochondria contacts; Mitofusin 2; MAM; Electron/confocal microscopy; Ca2+ signaling; SPLICS;
Heme oxygenase-1 protects liver against ischemia/reperfusion injury via phosphoglycerate mutase family member 5-mediated mitochondrial quality control
Keywords: میتوفوسین 2; ALT; Alanine aminotransferase; Drp1; dynamin-related protein 1; EDTA; ethylenediaminetetraacetic acid; GDH; glutamate dehydrogenase; H&E; hematoxylin&eosin; HO-1; heme oxygenase-1; H/R; hypoxia/reoxygenation; IL; interleukin; I/R; ischemia/reperfusion; LP
Mitochondria as pharmacological targets in Down syndrome
Keywords: میتوفوسین 2; AD; Alzheimer's disease; AGO; Argonaute proteins; AMPK; AMP-activated protein kinase; ANTs; adenine nucleotide translocators; AK; adenylate kinase; APP; amyloid-β precursor protein; ASD; autism spectrum disorder; CAT; catalase; CNS; central nervous syste
FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission
Keywords: میتوفوسین 2; AGEs; advanced glycation end products; Drp1; dynamin-relatedprotein-1; ECs; endothelial cells; FOXO1; forkhead box O1; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HUVECs; human umbilical vein endothelial cells; HG; high glucose concentration; mtROS;
Progesterone treatment modulates mRNA OF neurosteroidogenic enzymes in a murine model of multiple sclerosis
Keywords: میتوفوسین 2; CC1; anti-adenomatours polyposis coli clone CC1; CD11b; cluster of differentiation molecule 11B; CFA; complete Freund adjuvant; DHP; dihydroprogesterone; EAE; experimental autoimmune encephalomyelitis; Fis1; mitochondrial fission 1; GABA; gamma-aminobutyr
Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice
Keywords: میتوفوسین 2; ALT; Alanine aminotransferase; ActD; Actinomycin D; CYP; Cytochrome P450; CQ; Chloroquine; Drp1; Dynamin-related protein 1; DHPAs; Dehydropyrrolizidine alkaloids; DHR; dehydroretronecine; EM; Electron microscopy; GSH; Glutathione; GAPDH; Glyceradehyde-3-p
Research PaperAge-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression
Keywords: میتوفوسین 2; CMT; Charcot-Marie-Tooth; DBA; DBA/2J; DOA; dominant optic atrophy; D2G; DBA/2JGpnmb +;  IOP; intraocular pressure; Mfn1; mitofusin 1; Mfn2; mitofusin 2; NICIF; nanoimmuno capillary isoelectric focusing; NP; NanoPro; ON; optic nerve; Opa1; optic atrophy
CDK5 inhibitors prevent astroglial apoptosis and reactive astrogliosis by regulating PKA and DRP1 phosphorylations in the rat hippocampus
Keywords: میتوفوسین 2; SE; status epilepticus; MFN1; mitofusin 1; MFN2; mitofusin 2; OPA1; optic atrophy 1; DRP1; dynamin-related protein 1; Fis-1; fission related protein-1; MFF; mitochondrial fission factor; CDK5; cyclin-dependent kinase 5; PKA; protein kinase A; AIF; apoptot
Coenzyme Q10 ameliorates cerebral ischemia reperfusion injury in hyperglycemic rats
Keywords: میتوفوسین 2; Ischemia; Coenzyme Q10; Hyperglycemia; Mitochondria; Fission 1; Mitofusin 2;
Inhibition of Drp1-mediated mitochondrial fission improves mitochondrial dynamics and bioenergetics stimulating neurogenesis in hippocampal progenitor cells from a Down syndrome mouse model
Keywords: میتوفوسین 2; AR; aspect ratio; BrdU; bromodeoxyuridine; CaN; calcineurin; DAPI; 4',6-diamidino-2-phenylindole; DCX; doublecortin; Drp1; dynamin-related protein 1; DS; Down syndrome; L-Opa; long Opa1; Mdivi-1; mitochondrial division inhibitor 1; Mnf2; mitofusin 2; NPCs
Globular CTRP3 promotes mitochondrial biogenesis in cardiomyocytes through AMPK/PGC-1α pathway
Keywords: میتوفوسین 2; AMPK; AMP-activated protein kinase; AraA; adenine 9-β-d-arabinofuranoside; ATP-5β; ATP synthase 5β; Cyt B; cytochrome B; CTRP3; C1q/tumor necrosis factor-related protein-3; FCCP; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone; H/R; hypoxia-reoxy
Effects of cultured Cordyceps mycelia polysaccharide A on tumor neurosis factor-α induced hepatocyte injury with mitochondrial abnormality
Keywords: میتوفوسین 2; Cordyceps sinensis mycelia polysaccharide A; Mitochondria abnormality; TNF-α receptor 1; Mitofusin 2; Apoptosis;
Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability
Keywords: میتوفوسین 2; OMM; outer mitochondrial membrane; DRP1; dynamin-related protein-1; MFN1; mitofusin 1; MFN2; mitofusin 2; mtDNA; mitochondrial DNA; PINK1; PTEN-induced putative kinase 1; PARK2; parkin; DOA; dominant optic atrophy; CMT2A; Charcot-Marie-Tooth neuropathy ty
Regulation of autophagy by mitochondrial phospholipids in health and diseases
Keywords: میتوفوسین 2; ALCAT1; lysocardiolipin acyltransferase 1; ALE1; lysophospholipid acyltransferase (yeast); AMPK; AMP-activated protein kinase; Atg; autophagy-related gene; ATGL; adipose triglyceride lipase; AVT1; amino acid vacuolar transport; BNIP3; BCL2/adenovirus E1B
Drp1 guarding of the mitochondrial network is important for glucose-stimulated insulin secretion in pancreatic beta cells
Keywords: میتوفوسین 2; Pancreatic beta cells; Dynamin-related protein 1 (Drp1); Mitochondrial fission; Mitochondrial dynamics; Glucose-stimulated insulin secretion; Drp1; dynamin-related protein 1; ER; endoplasmic reticulum; Fis1; fission protein 1; Mff; mitochondrial fission f
Influence of the APOE genotype on hepatic stress response: Studies in APOE targeted replacement mice and human liver cells
Keywords: میتوفوسین 2; AD; Alzheimer's disease; APOE; apolipoprotein E; ATP; adenosine triphosphate; ATP5A1; ATP synthase subunit alpha, mitochondrial; B2M; beta-2 microglobulin; BAX; BCL2-associated X protein; BCL2; B-cell leukemia/lymphoma 2; BiP; binding immunoglobulin prote
Analysis of mitochondrial structure and function in the Drosophila larval musculature
Keywords: میتوفوسین 2; ATP; adenosine triphosphate; AEL; after egg laying; CMT2A; Charcot-Marie-Tooth Type 2A; ConA; concanavalin A; Drp1; dynamin-related protein; DOA; dominant optic atrophy; GFP; green fluorescent protein; IFM; indirect flight muscle; IMF; intermyofibrill
Candesartan cilexetil attenuated cardiac remodeling by improving expression and function of mitofusin 2 in SHR
Keywords: میتوفوسین 2; LVH; left ventricular hypertrophy; VSMC; vascular smooth muscle cell; EH; essential hypertension; Mfn2; mitofusin 2; SHR; spontaneously hypertensive rat; WKY; Wistar-Kyoto rat; ÎÏm; mitochondrial membrane potential; ROS; reactive oxygen species; BW; bod
Rg1 prevents myocardial hypoxia/reoxygenation injury by regulating mitochondrial dynamics imbalance via modulation of glutamate dehydrogenase and mitofusin 2
Keywords: میتوفوسین 2; H/R; hypoxia/reoxygenation; I/R; ischemia/reperfusion; CK; creatine kinase; LDH; lactate dehydrogenase; ROS; reactive oxygen species; OCR; oxygen consumption rate; ECAR; extracellular acidification rate; α-KG; α-ketoglutaric acid; GDH; glutamate dehydro
Epigallocatechin gallate and mitochondria-A story of life and death
Keywords: میتوفوسین 2; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; ALT; alanine aminotransferase; AMP; adenosine monophosphate; AP-1; activator protein-1; ASK1; apoptosis signal-regulating kinase 1; ATP; adenosine triphosphate; Bax; BCL2-Associated X Protein; Bc
PGC-1α overexpression via local transfection attenuates mitophagy pathway in muscle disuse atrophy
Keywords: میتوفوسین 2; PGC-1α; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; FoxO; forkhead box O; 4-HNE; 4-hydroxynonenal; Mul1; mitochondrial E3 ubiquitin protein ligase 1; PINK1; PTEN-induced putative kinase 1; Mfn2; mitofusin 2; mROS; mitochondrial
miR-106a promotes cardiac hypertrophy by targeting mitofusin 2
Keywords: میتوفوسین 2; miR-106a; Mitofusin 2; miRNAs; Angiotensin II; Hypertrophy;
A cohort study of Han Chinese MFN2-related Charcot-Marie-Tooth 2A
Keywords: میتوفوسین 2; Mitofusin 2; Early onset; Hereditary neuropathy; Charcot-Maria-Tooth; Axonal neuropathy; Pathology;
MFN2-related neuropathies: Clinical features, molecular pathogenesis and therapeutic perspectives
Keywords: میتوفوسین 2; Mitofusin 2; Mitochondrial network; Neurodegeneration; Charcot-Marie-Tooth disease type 2A; Clinical and genetic features; Pathogenetic mechanisms;
Mitofusin 2 ameliorates hypoxia-induced apoptosis via mitochondrial function and signaling pathways
Keywords: میتوفوسین 2; AIf; apoptosis-inducing factor; ANOVA; analysis of variance; ATP; adenosine triphosphate; Bcl-2; B Cell Leukemia 2; Bax; Bcl-2 associated X protein; CCA; common carotid artery; CCK-8; cell counting kit-8; CoCl2; cobalt chloride; Ct; critical threshold; DM
Epigallocatechin-3-gallate inhibits proliferation of human aortic smooth muscle cells via up-regulating expression of mitofusin 2
Keywords: میتوفوسین 2; Epigallocatechin-3-gallate; Ras-Raf-ERK/MAPK; Human aortic smooth muscle cell; Proliferation; Mitofusin 2; siRNA