دانلود مقالات ISI درباره حالت عمل + ترجمه فارسی

Finding synergies for 3Rs - Toxicokinetics and read-across: Report from an EPAA partners' Forum

Keywords: حالت عمل; Physiologically-based kinetic (PBK) modelling; Hazard and risk assessment; Weight-of-evidence (WoE); Threshold of toxicological concern (TTC); In vitro to in vivo extrapolation (IVIVE); Integrated approach for testing and assessment (IATA); Absorption; Di

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

The challenge of the application of 'omics technologies in chemicals risk assessment: Background and outlook

Keywords: حالت عمل; Omics; Transcriptomics; Weight-of-evidence; Registration, Evaluation, Authorisation, and Restriction (REACH); Plant protection products; Regulatory toxicology; Hazard assessment; Test method validation; Test method standardisation; AOP; Adverse outcome pa

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop

Keywords: حالت عمل; Regulatory toxicology; Transcriptomics; Metabolomics; Good laboratory practice (GLP); Weight-of-evidence (WoE); Adverse outcome pathway (AOP); Mode-of-action (MoA); Gene expression; Differentially expressed genes; ANOVA; Analysis of variance; AOP; Adverse

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

A generic Transcriptomics Reporting Framework (TRF) for 'omics data processing and analysis

Keywords: حالت عمل; Regulatory toxicology; Normalisation of 'omics data; Statistical analysis; Differentially expressed genes; Reproducibility; Bioinformatics; Gene expression; ADI; Acceptable daily intake level; ANOVA; Analysis of variance; CEFIC; European Chemical Indust

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents

Keywords: حالت عمل; AAG; alkyladenine DNA glycosylase; ATM; ataxia telangiectasia mutated; BER; base excision repair; BPD; break point dose; BMD; benchmark dose; BMDL; benchmark dose lower confidence limit; CSBP; computational systems biology pathway; DSB; double strand brea

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

A decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping)

Keywords: حالت عمل; AOP; adverse outcome pathway; APPIE; Association of Powder Process Industry; ASTM; American Society for Testing and Materials; ATP; adenosine triphosphate; BAM; German Federal Institute for Materials Research and Testing; BAuA; German Federal Institute fo

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2015 سفارش ترجمه

Kv7 channels as targets for anti-epileptic and psychiatric drug-development

Keywords: حالت عمل; KCNQ; Kv7; Anti-manic; Anti-psychotic; Anti-convulsion; Mode-of-action;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Toxicogenomics: The challenges and opportunities to identify biomarkers, signatures and thresholds to support mode-of-action

Keywords: حالت عمل; Toxicogenomics; Mode-of-action; Biomarkers; Liver carcinogenesis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

A consistent and transparent approach for calculation of Derived No-Effect Levels (DNELs) for petroleum substances

Keywords: حالت عمل; ACGIH; American Conference of Governmental Industrial Hygienists; AD; Animal Dose; AF; Assessment Factor; BW; body weight; CLP; Classification, Labelling and Packaging Regulation; CNS; Central Nervous System; CSA; Chemical Safety Assessment; CSR; Chemical

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: A dynamic and kinetic evaluation of a putative mode-of-action

Keywords: حالت عمل; TCS, triclosan; TH, thyroid hormones; T4, thyroxine; T3, triiodothyronine; MOA, mode-of-action; GD, gestational day; PND, postnatal dayTriclosan; Mode-of-action; Thyroid disruption; Developmental exposure

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Comparative analysis of pharmaceuticals versus industrial chemicals acute aquatic toxicity classification according to the United Nations classification system for chemicals. Assessment of the (Q)SAR predictability of pharmaceuticals acute aquatic toxicit

Keywords: حالت عمل; Pharmaceuticals; Aquatic toxicity; GHS; Mode-of-action; Hazard assessment; (Q)SAR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Naphthalene metabolism in relation to target tissue anatomy, physiology, cytotoxicity and tumorigenic mechanism of action

Keywords: حالت عمل; Naphthalene; Cancer; Carcinogenicity; Tumorigenesis; Mode-of-action; Mechanism of action; Cytotoxicity; Olfactory epithelial neuroblastoma; Respiratory epithelial adenoma; Inflammation; Metabolism; Cytochrome P450; 1,2-Naphthoquinone; 1,4-Naphthoquinone;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Databases applicable to quantitative hazard/risk assessment—Towards a predictive systems toxicology

Keywords: حالت عمل; Data integration; Toxicogenomics; Predictive toxicology; Carcinogenicity; Mode-of-action; Genotoxicity

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Analysis of in vivo mutation data can inform cancer risk assessment

Keywords: حالت عمل; Cancer risk assessment; Mode-of-action; Mutagenic carcinogen; Nonmutagenic carcinogen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Rapid test for distinguishing membrane-active antibacterial agents

Keywords: حالت عمل; Antibacterial agents; Mode-of-action; Bacterial membrane

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Effects of methoprene, nonylphenol, and estrone on the vitellogenesis of the mysid Neomysis integer

Keywords: حالت عمل; Crustacea; Endocrine disruption; ELISA; Mode-of-action; Invertebrate

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه