دانلود مقالات ISI درباره MPP +، 1-Methyl-4-phenylpyridinium + ترجمه فارسی

هورمون گیاه استروئیدی: اثرات خارج از پادشاهی گیاه

Steroid plant hormones: Effects outside plant kingdom

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; BS, brassinosteroids; CC50, 50% cytotoxic concentration; EBl, 24-epibrassinolide; EC50, half maximal effective concentration; HSV, herpes simplex virus; HBl, 28-homobrassinolide; MPP+, 1-methyl-4-phenylpyridinium; TNF-α, tumor necrosis factor αBrassinoste

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

افزایش فسفوریلاسیون 14-3-3 در بیماری پارکینسون موجب کاهش پتانسیل عصبی پروتئین 14-3-3 می شود

Increased 14-3-3 phosphorylation observed in Parkinson's disease reduces neuroprotective potential of 14-3-3 proteins

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; αsyn, alpha-synuclein; CK, casein kinase; GFP, green fluorescent protein; LDH, lactate dehydrogenase; LRRK2, leucine-rich repeat kinase 2; MPP+, 1-Methyl-4-phenylpyridinium; n.s, not significant; PD, Parkinson's disease; PBS, phosphate-buffered saline; SN

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Hydroxytyrosol induces phase II detoxifying enzyme expression and effectively protects dopaminergic cells against dopamine- and 6-hydroxydopamine induced cytotoxicity

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; Hydroxytyrosol; Parkinson's disease; Dopamine; Oxidative stressPD, Parkinson's disease; DA, Dopamine; DAQ, Dopamine quinone; HT, Hydroxytyrosol; SF, Sulforaphane; 6-OHDA, 6-Hydroxydopamine; MPP+, 1-Methyl-4-phenylpyridinium; ROS, Reactive oxygen species;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The neuroprotective effect of lovastatin on MPP+-induced neurotoxicity is not mediated by PON2

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; MPP+, 1-methyl-4-phenylpyridinium; PD, Parkinson's disease; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydrophenylpyridine; MAO-B, monoamine oxidase B; DA, dopamine; ROS, reactive oxidant species; PON2, paraoxonase-2; HVA, homovanillic acid; DOPAC, 3,4-dihydrox

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Dopamine and its metabolites in cathepsin D heterozygous mice before and after MPTP administration

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+, 1-methyl-4-phenylpyridinium; 3-MT, 3-methoxytyramine; MHPG, 3-methoxy-4-hydroxyphenylglycol; DOPAC, 3,4-dihydroxymethylphenylacetic acid; 5-HIAA, 5-hydroxyindoleacetic acid; 5-HT, 5-hydroxytryptami

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Tissue transglutaminase cross-links beclin 1 and regulates autophagy in MPP+-treated human SH-SY5Y cells

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; PD, Parkinson’s disease; MPP+, 1-methyl-4-phenylpyridinium; tTG, tissue transglutaminase; ER, endoplasmic reticulum; LBs, Lewy-bodies; RA, retinoic acidParkinson’s disease; Autophagy; SH-SY5Y; Tissue transglutaminase; Beclin 1; Endoplasmic reticulum

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenetic histone acetylation and deacetylation mechanisms in experimental models of neurodegenerative disorders

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; MPP+, 1-methyl-4-phenylpyridinium; 4-PBA, 4-phenylbutyrate; AD, Alzheimer's disease; Aβ, amyloid-beta peptide; APP, β-amyloid precursor protein; HAT, histone acetyl transferase; HDACs, histone deacetylases; HD, Huntington's disease; PD, Parkinson's diseas

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Matrix metalloproteinase-3 is activated by HtrA2/Omi in dopaminergic cells: Relevance to Parkinson’s disease

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; ER, endoplasmic reticulum; FBS, fetal bovine serum; HtrA2/Omi, High temperature requirement A2; MMP-3, matrix metalloproteinase-3; MPP+, 1-methyl-4-phenylpyridinium; PD, Parkinson’s disease; RT-PCR, reverse transcription-polymerase chain reactionHtrA2/Omi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular effects of activated BV-2 microglia by mitochondrial toxin 1-methyl-4-phenylpyridinium

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; CD68, cluster of differentiation 68; FACS, registered trademark of Becton Dickinson and Company; FITC, fluorescein isothiocyanate; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; MAC-1, macrophage antigen complex-1; MPP+, 1-methyl-4-phenylpyridinium; MPT

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Genetically engineered mouse models of Parkinson's disease

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; MPTP, 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine; MPP+, 1-methyl-4-phenylpyridinium; 6-OHDA, 6-hydroxydopamine; COMT, catechol-O-methyltransferase; DA, dopamine; DAT, dopamine transporter; L-DOPA, levodopa; LB, Lewy body; LPS, lipopolysaccharride; MAOB,

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of cryopreservation on the activity of OATP1B1/3 and OCT1 in isolated human hepatocytes

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; E217βG, estradiol-17β-glucuronide; MPP+, 1-methyl-4-phenylpyridinium; OATP1B1/3, Organic Anion Transporting Polypeptide 1B1 and 1B3; SLCO, Solute carrier organic anion transporter; SLC, Solute Carrier; OCT1, Organic Cation Transporter 1Cryopreserved hepat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Implication of the c-Jun-NH2-terminal kinase pathway in the neuroprotective effect of puerarin against 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in PC-12 cells

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; ANOVA, one way analysis of variance; Ct, threshold cycles; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; JNK, c-Jun N-terminal kinase; LDH, lactate dehydrogenase; MPP+, 1-methyl-4-phenylpyridinium; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazol

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Myricetin attenuated MPP+-induced cytotoxicity by anti-oxidation and inhibition of MKK4 and JNK activation in MES23.5 cells

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; Myricetin; MPP+; Oxidative stress; MKK4MPTP, 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine; MPP+, 1-methyl-4-phenylpyridinium; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide; JNK, c-Jun N-terminal kinase; DA, dopamine; DMEM/F12, Eagl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Deprenyl prevents MPP+-induced oxidative damage in PC12 cells by the upregulation of Nrf2-mediated NQO1 expression through the activation of PI3K/Akt and Erk

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; PD, Parkinson's disease; ROS, reactive oxygen species; ARE, antioxidant response element; Nrf2, nuclear factor erythroid 2-related factor 2; MAO-B, B-type monoamine oxidase; NQO1, NAD(P)H quinone oxidoreductase 1; MPP+, 1-methyl-4-phenylpyridinium; Erk, e

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; CHHS, cryopreserved human hepatocyte suspensions; E2-17β-G, etradiol-17β-d-glucuronide; MPP+, 1-methyl-4-phenylpyridinium; NTCP/Ntcp, Na+-taurocholate co-transporting peptide (Human/Rat); OAT/Oat, organic anion transporter (Human/Rat); OATP/Oatp, organic

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; DA, Dopamine; PD, Parkinson's disease; MPP+, 1-methyl-4-phenylpyridinium; HDACs, Histone deacetylases; HDACIs, Histone deacetylase inhibitors; NaB, Sodium butyrate; VPA, Valproic acid; SAHA, Suberoylanilide hydroxamic acid; IAP's, Inhibitors of Apoptosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Rg1 protects the MPP+-treated MES23.5 cells via attenuating DMT1 up-regulation and cellular iron uptake

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; Parkinson's disease; 1-Methyl-4-phenylpyridinium (MPP+); Divalent metal transporter 1 (DMT1); NF-κB; Rg1SN, substantia nigra; SNpc, substantia nigra pars compacta; PD, Parkinson's disease; MPP+, 1-methyl-4-phenylpyridinium; DMT1, divalent metal transporte

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; AIF, apoptosis-inducing factor; Dld, dihydrolipoamide dehydrogenase; DNP, 2,4 dinitrophenylhydrazone; DNPH, 2,4 dinitrophenylhydrazine; DTNB, 5,5′-dithiobis-(2-nitrobenzoic acid); Hq, harlequin; MPP+, 1-methyl-4-phenylpyridinium; SOD, superoxide dismutase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Substrate discrimination by ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5: Gain-of-function by interchange of selected amino acids

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; CT, carnitine; CTT, carnitine transporter; ET, ergothioneine; ETT, ergothioneine transporter; LC, liquid chromatography; MPP+, 1-methyl-4-phenylpyridinium; MS, mass spectrometry; TMS, transmembrane segmentCarnitine transporter; Ergothioneine transporter;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in MES23.5 cells

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; SN, substantia nigra; PD, Parkinson's disease; MPP+, 1-methyl-4-phenylpyridinium; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; DMT1, divalent metal transporter 1; IRE, iron responsive element; TfR, transferrin receptor; UTR, untranslational region;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; AFR, ascorbate free radical; CNS, central nervous system; CSF, cerebrospinal fluid; DHA, dehydroascorbic acid; GLUT, glucose transporter; GSH, glutathione; HIF-1α, hypoxia-inducible factor 1α; MPP+, 1-methyl-4-phenylpyridinium; MPTP, 1-methyl-4-phenyl-1,2

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Mitochondria and ubiquitin-proteasomal system interplay: Relevance to Parkinson's disease

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; DAergic, dopaminergic; DCFH2DA, 2,7′-dichlorofluorescein diacetate; ETC, electron transport chain; LBs, Lewy bodies; MPP+, 1-methyl-4-phenylpyridinium; MPTP, 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine; mtDNA, mitochondrial DNA; NT2, human teratocarcinom

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Nitration of soluble proteins in organotypic culture models of Parkinson's disease

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; AMPT, α-methyl-p-tyrosine; DA, dopamine; DOPA, 3,4-dihydroxyphenylalanine; HBSS, Hanks balanced salt solution; LDH, lactate dehydrogenase; l-NAME, N-nitro l-arginine methyl ester; MPP+, 1-methyl-4-phenylpyridinium; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahyd

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Magnesium exerts both preventive and ameliorating effects in an in vitro rat Parkinson disease model involving 1-methyl-4-phenylpyridinium (MPP+) toxicity in dopaminergic neurons

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; Mg, magnesium; MPP+, 1-methyl-4-phenylpyridinium; PD, Parkinson disease; TH, tyrosine hydroxylaseMagnesium; 1-methyl-4-phenylpyridinium; Dopaminergic neuron; Ventral mesencephalic–striatal co-culture; Parkinson disease

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; 6-OHDA, 6-hydroxydopamine; BBB, blood–brain barrier; DA, dopamine; DAergic, dopaminergic; DDC, diethyldithiocarbamate; Fe–S, iron–sulfur; GSH, glutathione; MPP+, 1-methyl-4-phenylpyridinium; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NOS, nitric

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Probing the substrate specificity of the ergothioneine transporter with methimazole, hercynine, and organic cations

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; ETT, ergothioneine transporter; LC, liquid chromatography; MPP+, 1-methyl-4-phenylpyridinium; MS, mass spectrometry; TEA, tetraethylammoniumSLC22A4; Chronic inflammatory disease; Ergothioneine; Ergothioneine transporter; Methimazole; Organic cations

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

17β-Estradiol reduces nitrotyrosine immunoreactivity and increases SOD1 and SOD2 immunoreactivity in nigral neurons in male mice following MPTP insult

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; DAB, 3,3′-diaminobenzidine tetrahydrochloride; E2, 17β-estradiol; -IR, immunoreactive; MPP+, 1-methyl-4-phenylpyridinium; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NT, nitrotyrosine; PBS, phosphate buffered saline; PD, Parkinson's disease; SEM,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Cortical regulation of dopamine depletion-induced dendritic spine loss in striatal medium spiny neurons

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; cortex; dendrite; glutamate; MPP+; Parkinson’s disease; striatumDIV, days in vitro; HVA, homovanillic acid; ir, immunoreactive; MPP+, 1-methyl-4-phenylpyridinium; MSN, medium spiny neuron; PD, Parkinson’s disease; TBS, Tris-buffered saline; TBS+, 50 mM Tr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

The role of organic cation transporter-3 in methamphetamine disposition and its behavioral response in rats

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; OCT3, organic cation transporter-3; METH, methamphetamine; OCT3-AS, antisense against OCT3; OCT3-SCR, scrambled antisense against OCT3; PFC, prefrontal cortex; NAcc, nucleus accumbens; MPP+, 1-methyl-4-phenylpyridinium; CP, choroid plexus; CSF, cerebrospi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Comparative analysis of the effects of resveratrol in two apoptotic models: Inhibition of complex I and potassium deprivation in cerebellar neurons

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; cerebellar granule cells; resveratrol; sirtinol; SIRT1; MPP+; serum and potassium withdrawalCGN, cerebellar granule neuron; Ct, cycle threshold; H2DCFDA, 2,7-dichlorodihydrofluorescein diacetate; MPP+, 1-methyl-4-phenylpyridinium; PBS, phosphate buffered

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; cyclin dependent kinases; apoptosis; cerebellar granule cells; flavopiridol; vitamin EAIF, apoptosis-inducing factor; CGN, cerebellar granule neuron; FLAV, flavopiridol; H2DCFDA, 2,7-dichlorodihydrofluorescein diacetate; MPP+, 1-methyl-4-phenylpyridinium;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

(−)-Epigallocatechin gallate regulates dopamine transporter internalization via protein kinase C-dependent pathway

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; 6-OHDA, 6-hydroxydopamine; DAT, dopamine transporter; EGCG, (−)-epigallocatechin gallate; MPP+, 1-methyl-4-phenylpyridinium; PKC, protein kinase C; PMA, phorbol 12-myristate 13-acetate; Sulfo-NHS-SS-Biotin, sulfosuccinimidyl 2-(biotinamido)-ethyl-1, 3-dit

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Enhancement of tyrosine hydroxylase expression and activity by Trypanosoma cruzi parasite-derived neurotrophic factor

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; PDNF, parasite-derived nerve factor; TH, tyrosine hydroxylase; MPP+, 1-methyl-4-phenylpyridinium; MAPK, mitogen-activated protein kinase; Erk, extracellular signal-regulated kinase; PKA, cAMP-dependent protein kinase A; NGF, nerve growth factorParasite-de

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

The parkinsonism producing neurotoxin MPP+ affects microtubule dynamics by acting as a destabilising factor

Keywords: MPP +، 1-Methyl-4-phenylpyridinium; DIC, differential interference contrast; MPP+, 1-methyl-4-phenylpyridinium; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson’s disease1-Methyl-4-phenylpyridinium; Microtubule; Dynamics; Cytoskeleton; Neurodegeneration; Parkinson’s disease

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه