Keywords: HHC; Human Hepatocellular Carcinoma; LCSLC; sliver cancer stem-like cells; TRPV2; Transient Receptor Potential Vanilloid-type 2 channel; TRP; Transient Receptor Potential; SCID; severe combined immunodeficiency; ALDH1; aldehyde dehydrogenase 1; GFP; green
مقالات ISI (ترجمه نشده)
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Keywords: Mrp1; Multidrug resistance proteins 1; Mrp2; Multidrug resistance proteins 2; Mrp3; Multidrug resistance proteins 3; Mrp4; Multidrug resistance proteins 4; Abcg2; ATP-binding cassette sub-family G member 2; Mrp transporters; Abcg2; Rat liver; Development;
Keywords: AC; adenylyl cyclase; AKT; protein kinase B; AMPK; AMP-activated protein kinase; AnR; androgen receptor; ARF6; ADP ribosylation factor 6; CaMK; Ca2+-calmodulin dependent kinase; CaMKK; CaMK kinase; cAMP; cyclic adenosine 3â²,5â²-monophosphate; CDK5; cyc
Structural patterns of the human ABCC4/MRP4 exporter in lipid bilayers rationalize clinically observed polymorphisms
Keywords: 6-MP; 6-mercaptopurine; ABC; ATP-binding cassette; ADV; adefovir; AZT; azidothymidine; BLOSUM; blocks substitution matrix; CFTR; cystic fibrosis transmembrane conductance regulator; Chol; cholesterol; cryo-EM; cryo-electronic microscopy; DMAV; dimethylars
Disruption of TFGβ-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand
Keywords: CDCA; chenodeoxycholic acid; CA; cholic acid; DCA; deoxycholic acid; LCA; litocholic acid; BAs; bile acids; BARS; bile acid activated receptors; GPBAR1; G protein coupled bile acid receptor; TGR5; Takeda G protein receptor 5; FXR; farnesoid x-receptor; PX
Gender-specific expression of ATP-binding cassette (Abc) transporters and cytoprotective genes in mouse choroid plexus
Keywords: CP; choroid plexus; BBB; blood-brain barrier; CSF; cerebrospinal fluid; Mrp; multidrug resistance-associated protein; Abc; ATP binding cassette; MTX; methotrexate; Mrp4; multidrug resistance-associated protein 4; BCSFB; blood-cerebrospinal fluid barrier;
Nonsteroidal anti-inflammatory drugs in-vitro and in-vivo treatment and Multidrug Resistance Protein 4 expression in human platelets
Keywords: Platelets; MRP4; NSAID; Osteoarthritis
Gene-gene interactions between DRD3, MRP4 and CYP2B6 polymorphisms and its influence on the pharmacokinetic parameters of efavirenz in HIV infected patients
Keywords: Efavirenz pharmacokinetics; Genetic factors; Gene-gene interactions; CYP2B6; MRP4; DRD3;
Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicosapentaenoic acid-derived PGE3
Keywords: NSAIDs; non-steroidal anti-inflammatory drugs; EPA-E; eicosapentaenoic acid ethyl ester; AA; arachidonic acid; PGE2; prostaglandin E2; PGE3; prostaglandin E3; EP; PGE receptor; OATP; organic anion transporting polypeptide; OAT; organic anion transporter;
The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4
Keywords: FLU; flutamide; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; CYP; cytochrome P450; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; 3-MC; 3-methylcholanthrene; ABCC4; ATP-binding cassette sub-family C member 4; MRP4; mul
N-linked glycans do not affect plasma membrane localization of multidrug resistance protein 4 (MRP4) but selectively alter its prostaglandin E2 transport activity
Keywords: ABC transporter; Membrane localization; MRP4; N-glycosylation; Polarized kidney cells; Prostaglandin E2 transport;
PKA and actin play critical roles as downstream effectors in MRP4-mediated regulation of fibroblast migration
Keywords: MEFs; mouse embryo fibroblasts; MRP4; multidrug resistance protein 4; PKA; protein kinase A; Rac; Ras-related C3 botulinum toxin substrate; SPT; single-particle tracking; VASP; vasodilator-stimulated phosphoprotein; WASP; Wiskott-Aldrich syndrome protei
MRP4 and CFTR in the regulation of cAMP and β-adrenergic contraction in cardiac myocytes
Keywords: MRP4; cAMP; β-Adrenergic signaling; Cardiac myocyte; CFTR
Expression of genes involved in xenobiotic metabolism and transport in end-stage liver disease: up-regulation of ABCC4 and CYP1B1
Keywords: liver disease; cytochrome P450; drug metabolism; CYP1B1; MRP4; alcohol liver disease; primary sclerosis cholangitis; HCV
Cellular accumulation of fluoroquinolones is not predictive of their intracellular activity: studies with gemifloxacin, moxifloxacin and ciprofloxacin in a pharmacokinetic/pharmacodynamic model of uninfected and infected macrophages
Keywords: Ciprofloxacin; Moxifloxacin; Gemifloxacin; Mrp4; Staphylococcus aureus; Listeria monocytogenes; Macrophages
Modulation of the expression of ABC transporters in murine (J774) macrophages exposed to large concentrations of the fluoroquinolone antibiotic moxifloxacin
Keywords: Moxifloxacin; Ciprofloxacin; Efflux; Mrp4; P-gp; Bcrp
Aspirin Extrusion From Human Platelets Through Multidrug Resistance Protein-4–Mediated Transport : Evidence of a Reduced Drug Action in Patients After Coronary Artery Bypass Grafting
Keywords: aspirin; bypass; MRP4; plateletsAA, arachidonic acid; ATP, adenosine triphosphate; bimane-GS, bimane-glutathione; CABG, coronary artery bypass grafting; CABG5, platelets obtained 5 days after coronary artery bypass grafting surgery; CABG10, platelets obta
Identification of MET and SRC Activation in Melanoma Cell Lines Showing Primary Resistance to PLX4032
Keywords: AK; adenylate kinase; AKT; v-akt murine thymoma viral oncogene homolog; ANOVA; analysis of variance; BCRP; breast cancer resistance protein; BRAF; v-raf murine sarcoma viral oncogene homolog B1; CCND1; cyclin D1; CRAF; v-raf-1 murine leukemia viral oncoge
Silencing MRP4 by small interfering RNA reverses acquired DDP resistance of gastric cancer cell
Keywords: Gastric cancer; MRP4; Multi-drug resistance; Chemotherapy; DDP
Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin
Keywords: Oxaliplatin; Ovarian carcinoma; ABC transporters; Cellular resistance; MRP4
Research ReportABC efflux transporters in brain vasculature of Alzheimer's subjects
Keywords: Blood-brain barrier; Alzheimer's disease; P-glycoprotein; MRP4; BCRP;
Involvement of NHERF1 in apical membrane localization of MRP4 in polarized kidney cells
Keywords: MRP4; NHERF1; Membrane trafficking; Polarized kidney cells; ABC transporter; Apical localization
cGMP (guanosine 3â²,5â²-cyclic monophosphate) transport across human erythrocyte membranes
Keywords: OSV; one-step inside-out membrane vesicles prepared by the spontaneous vesiculation method; SKNV; inside-out membrane vesicles prepared by the modified Steck and Kant; Nycodenz method; Erythrocyte; cGMP; ABC transporter; Multidrug-resistance associated pr
Up-regulation of Mrp4 expression in kidney of Mrp2-deficient TRâ rats
Keywords: Mrp; multidrug resistance-associated protein; TRâ; transport-deficient rat; UGT; UDP-glucuronosyltransferase; bDNA; branched DNA; PAH; p-aminohippurate; CYP; cytochrome P450; Mrp4; Mrp2; TRâ rat; Kidney; Up-regulation; Gunn rat;