Keywords: بیماری کبد چرب غیرالکلی; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; BMI; body mass index; AST; aspartate aminotransferase; ALT; alanine aminotransferase; GGT; gammaglutamyltranspaptidase; NAS; NAFLD activity score; HOMA-IR; homeostasis model as
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Keywords: بیماری کبد چرب غیرالکلی; CESD; cholesteryl ester storage disease; LAL; lysosomal acid lipase; CE; cholesteryl ester; TG; triglyceride; ERT; enzyme replacement therapy; NAFLD; non-alcoholic fatty liver disease; Wolman disease; Cholesteryl ester storage disease; 1H MR spectroscopy;
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; CRN; Clinical Research Network; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AGL; acquired generalized lipodystrophy; CGL; congenital generalized lipodystrop
Keywords: بیماری کبد چرب غیرالکلی; BMI; Body mass index; FFA; Free fatty acids; GDM; Gestational diabetes mellitus; IHCL; Intrahepatocellular lipid; IV; Intravenous; MRI; Magnetic resonance imaging; MRS; Magnetic resonance spectroscopy; NAFLD; Nonalcoholic fatty liver disease; TE; Echo tim
Keywords: بیماری کبد چرب غیرالکلی; ACC-1; acetyl-CoA carboxylase-1; ERK1/2; extracellular signal-regulated kinase 1/2; FAS; fatty acid synthase; FFAs; free fatty acids; HPS; hepassocin; NAFLD; non-alcoholic fatty liver disease; NAS; NAFLD activity score; NASH; non-alcoholic steatohepatitis
Keywords: بیماری کبد چرب غیرالکلی; HCC; hepatocellular carcinoma; NAFLD; non-alcoholic fatty liver disease; IMS; imaging mass spectrometry; MALDI; matrix-assisted laser desorption/ionization; LPCAT; lysophosphatidylcholine acyltransferase; PCA; principal component analysis; cPLA2α; cytoso
Keywords: بیماری کبد چرب غیرالکلی; Gutmicrobiota; Human Disease; Fecal Transplantation; Therapy; CDI; Clostridium difficile infection; FMT; fecal microbiota transplantation; IBD; inflammatory bowel disease; NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; SCFA;
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; non-alcohol-related fatty liver; DDR; DNA damage response; γ-H2AX; phosphorylated histone H2AX; Q-FISH; quantitative fluorescent in situ hybridization; MCM; minichromosome maintenance protein; PH3; phosphorylated histone 3; MFI; mean fluorescent i
Keywords: بیماری کبد چرب غیرالکلی; PT; prothrombin time; aPTT; activated partial thromboplastin time; PVT; portal vein thrombosis; LMWH; low molecular weight heparin; DVT; deep vein thrombosis; VKA; vitamin K antagonists; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steato
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; T2DM; type 2 diabetes mellitus; LB; liver biopsy; Se; sensitivity; Sp; specificity; ROC; receiver operating characteristic; AUROC; area under ROC; NPV; negative predictive valu
Keywords: بیماری کبد چرب غیرالکلی; Epidemiology; Burden; Liver disease; Cirrhosis; Primary liver cancer; Hepatocellular carcinoma; Alcohol-related liver disease; Hepatitis; NAFLD;
Keywords: بیماری کبد چرب غیرالکلی; Mancozeb; Fungicide hepatoxicity; NAFLD; HepG2NAFLD, nonalcoholic fatty liver disease; HepG2, hepatocarcinoma cell line; LDH, intracellular lactate dehydrogenase; MTT, tetrazolium dye 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; FA, fatty
Keywords: بیماری کبد چرب غیرالکلی; CGA, chlorogenic acid; MEC, multiethnic cohort; MRP, Maillard reaction products; NAFLD, nonalcoholic fatty liver diseasecoffee; hepatocellular carcinoma; fibrosis; cirrhosis; mortality; NAFLD
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; ALD; MortalityAAH, acute alcoholic hepatitis; ALD, alcoholic fatty liver disease; BMI, body mass index; HCC, hepatocellular carcinoma; HRQL, health-related quality of life; NAFLD, nonalcoholic fatty liver disease; NHANES, National Health and Nutrit
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; NASH; Microbiome; Liver
Keywords: بیماری کبد چرب غیرالکلی; Diabetes risk; Epidemiology; NAFLD; Non-alcoholic fatty liver disease; Type 2 diabetes
Keywords: بیماری کبد چرب غیرالکلی; ADME; absorption distribution metabolism and excretion; AFP; alpha-fetoprotein; BCLC; Barcelona Clinic Liver Cancer; Chk 1; check point 1; HBV; Hepatitis B Virus; HCC; hepatocellular carcinoma; HCV; Hepatitis C Virus; LT; liver transplatation; NAFLD; nona
Keywords: بیماری کبد چرب غیرالکلی; TF; transcription factor; TFBS; transcription factor binding sites; GEP; gene expression profiling; NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; LXR; liver X receptor; PPAR; peroxisome proliferator-activated receptor; HNF;
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; PPAR; Peroxisome proliferator-activated receptor; SNPs; single nucleotide polymorphisms; Nonalcoholic fatty liver disease; NASH; PPAR; Polymorphism;
Research paperPatatin-like phospholipase domain-containing protein 3 (PNPLA3): A potential role in the association between liver disease and bipolar disorder
Keywords: بیماری کبد چرب غیرالکلی; Bipolar disorder; Affective disorder; Patatin-like phospholipase domain-containing protein 3; PNPLA3; Non-alcoholic fatty liver disease; NAFLD;
Gene polymorphisms of desaturase enzymes of polyunsaturated fatty acid metabolism and adiponutrin and the increased risk of nonalcoholic fatty liver disease
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; nonalcoholic fatty liver disease; MetS; metabolic syndrome; PUFAs; polyunsaturated fatty acids; CAD; coronary artery disease; CVD; cardiovascular disease; PNPLA3; patatin-like phospholipase domain containing protein-3; GWAS; genome wide association
Microarray data and pathway analyses for primary human activated hepatic stellate cells compared to HepG2 human hepatoma cells
Keywords: بیماری کبد چرب غیرالکلی; Hepatocyte; Stellate cell; Liver; NAFLD;
Nrf2 is crucial for the down-regulation of Cyp7a1 induced by arachidonic acid in Hepg2 cells
Keywords: بیماری کبد چرب غیرالکلی; AA; arachidonic acid; CYP7A1; cholesterol 7α-hydroxylase; FA; fatty acid; HFD; high-fat diet; NAFLD; non-alcoholic fatty liver disease; Nrf2; nuclear factor erythroid-derived 2-like 2; siRNA; small interfering RNA; NAFLD; Nrf2; CYP7A1; HepG2; Arachidonic
Saponins from the roots of Platycodon grandiflorum ameliorate high fat diet-induced non-alcoholic steatohepatitis
Keywords: بیماری کبد چرب غیرالکلی; ACOX; acyl-CoA oxidase; ARE; antioxidant response element; CKS; Platycodon grandiflorum root-derived saponins; CPT-1; carnitine palmitoyltransferase-1; HFD; High fat diet; HSCs; hepatic stellate cells; NAFLD; non-alcoholic fatty liver disease; NASH; non-a
Antioxidant and anti-inflammatory effects of Chinese propolis during palmitic acid-induced lipotoxicity in cultured hepatocytes
Keywords: بیماری کبد چرب غیرالکلی; Propolis; Polyphenols; Lipoapoptosis; Hepatocytes; NAFLD;
Time-course microarrays reveal early activation of the immune transcriptome in a choline-deficient mouse model of liver injury
Keywords: بیماری کبد چرب غیرالکلی; CD; choline deficient; NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; VLDL; very low density lipoprotein; PC; phosphatidylcholine; Stat1; signal transducer and activator of transcription 1; FADS; fatty acid desaturases; ELOVL
MicroRNA-206 prevents hepatosteatosis and hyperglycemia by facilitating insulin signaling and impairing lipogenesis
Keywords: بیماری کبد چرب غیرالکلی; Insulin signaling; Lipogenesis; Hyperglycemia; NAFLD; MicroRNAs; Phosphorylation; Diet, high-fat;
Histone modifications in FASN modulated by sterol regulatory element-binding protein 1c and carbohydrate responsive-element binding protein under insulin stimulation are related to NAFLD
Keywords: بیماری کبد چرب غیرالکلی; Histone modification; SREBP-1c; ChREBP; NAFLD; IR; Hepatocyte steatosis;
The assessment of the chronic hepatotoxicity induced by Polygoni Multiflori Radix in rats: A pilot study by using untargeted metabolomics method
Keywords: بیماری کبد چرب غیرالکلی; TCM; Traditional Chinese Medicine; HSW; He-Shou-Wu; DILI; Drug-Induced Live Injury; NAFLD; Non-Alcoholic Fatty Liver Disease; LC-MS; Liquid-Chromatography-Tandem Mass Spectrometry; GC-MS; Gas Chromatography-Mass Spectrometry; TSG; 2,3,5,4â²-tetrahydr
Zoledronic acid, an FPPS inhibitor, ameliorates liver steatosis through inhibiting hepatic de novo lipogenesis
Keywords: بیماری کبد چرب غیرالکلی; Zoledronic acid (PubChem CID: 6099949); NAFLD; Zoledronic acid; Protein prenylation; Lipid metabolism;
Research ArticleAntioxidant properties of tea blunt ROS-dependent lipogenesis: beneficial effect on hepatic steatosis in a high fat-high sucrose diet NAFLD obese rat model
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; Camellia sinensis; Antilipogenesis; Antioxidant; Mitochondrial ROS; Obesogenic diet;
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; NLRP3; Inflammasomes; Cholesterol crystals; Kupffer cells; Hepatocytes; Interleukin-1β; Fibrosis; Diet, atherogenic; Methionine; NLR proteins;
Effects of polyphenol compounds melanin on NAFLD/NASH prevention
Keywords: بیماری کبد چرب غیرالکلی; ANOVA; analysis of variance; NAFLD; non, alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; TLR; toll-like receptor; T2DM; type 2 diabetes mellitus; ROS; reactive oxygen species; MSG; monosodium glutamate; IL; interleukin; INF; interferon
Sorafenib: A potential therapeutic drug for hepatic fibrosis and its outcomes
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; Non-alcoholic fatty liver disease; NASH; Non-alcoholic steatohepatitis3; ECM; Extracellular matrix; VEGF-R; Vascular endothelial growth factor receptor; PDGF-R; Platelet-derived growth factor receptor; c-KIT; c-kit proto-oncogene protein; FLT-3; FM
Zinc alpha2 glycoprotein alleviates palmitic acid-induced intracellular lipid accumulation in hepatocytes
Keywords: بیماری کبد چرب غیرالکلی; Non-alcoholic fatty liver disease; Triglycerides; Fatty acid oxidation; Lipogenesis; Nuclear receptors; Adiponectin; ZAG; zinc alpha2 glycoprotein; NAFLD; non-alcoholic fatty liver disease; TG; triglycerides; PA; palmitic acid; SREBP-1c; sterol-regulatory
APD668, a G protein-coupled receptor 119 agonist improves fat tolerance and attenuates fatty liver in high-trans fat diet induced steatohepatitis model in C57BL/6 mice
Keywords: بیماری کبد چرب غیرالکلی; GPR119 agonist; GLP-1; Triglyceride; Gastric emptying; NAFLD; NASH;
CD44 is a key player in non-alcoholic steatohepatitis
Keywords: بیماری کبد چرب غیرالکلی; CD44; Liver; NAFLD; Steatosis; NASH; MCP1; Macrophages;
Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro
Keywords: بیماری کبد چرب غیرالکلی; Wogonin; NAFLD; Oxidative stress; PPARα; AdipoR2;
Apigenin, a modulator of PPARγ, attenuates HFD-induced NAFLD by regulating hepatocyte lipid metabolism and oxidative stress via Nrf2 activation
Keywords: بیماری کبد چرب غیرالکلی; Apigenin; NAFLD; Nrf2; PPARγ;
Activation of the Hypoxia Inducible Factor 1α Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones
Keywords: بیماری کبد چرب غیرالکلی; Gallstone; NAFLD; Hypoxia; Aquaporin-8; AQP; aquaporin; CCD; cholesterol and cholate-rich diet; cDNA; complementary DNA; HIF1; hypoxia-inducible factor 1; HIF1α; hypoxia-inducible factor 1 α subunit; Hmox1; heme oxygenase-1; IBDU; isolated bile duct uni
Does bilirubin prevent hepatic steatosis through activation of the PPARα nuclear receptor?
Keywords: بیماری کبد چرب غیرالکلی; Heme oxygenase; Bilirubin; Biliverdin; NAFLD; NASH; Non-alcoholic fatty liver disease; PPAR; PPARα; SPPARM; Nuclear receptors;
Original articleInvestigating the effects of an oral fructose challenge on hepatic ATP reserves in healthy volunteers: A 31P MRS study
Keywords: بیماری کبد چرب غیرالکلی; ATP; Fructose infusion; Oral challenge; NAFLD; Liver; 31P MRS; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; ATP; adenosine triphosphate; MRS; magnetic resonance spectroscopy; Pi; inorganic phosphate; PDE; phosphodiesters;
Correlation between non-alcoholic fatty liver disease (NAFLD) and dyslipidemia in type 2 diabetes
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; Dyslipideamia; Metabolic disorders; Ultrasound sonography
Progression of carotid vascular damage and cardiovascular events in non-alcoholic fatty liver disease patients compared to the general population during 10Â years of follow-up
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; Intima-media thickness; Carotid plaques; Cardiovascular events; NASH;
Insulin resistance, postprandial GLP-1 and adaptive immunity are the main predictors of NAFLD in a homogeneous population at high cardiovascular risk
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; GLP-1; Inflammation; HDL; Insulin resistance; IFN-g
Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy
Keywords: بیماری کبد چرب غیرالکلی; NAFLD; non-alcoholic fatty liver disease; GWAS; genome-wide association study; PNPLA3; patatin-like phospholipase domain-containing-3; TM6SF2; transmembrane 6 superfamily member 2; GCKR; glucokinase regulatory protein; IRGM; immunity-related GTPase family
Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties
Keywords: بیماری کبد چرب غیرالکلی; Farnesoid X receptor; FXR agonist; GW4064; High fat diet; C57BL/6J mice; NAFLD; NASH
Non-alcoholic fatty liver disease (NAFLD) potentiates autoimmune hepatitis in the CYP2D6 mouse model
Keywords: بیماری کبد چرب غیرالکلی; Autoimmune hepatitis; NAFLD; CYP2D6; Mouse model; Hepatic fibrosisNAFLD, non-alcoholic fatty liver disease; NASH, non-alcoholic steatohepatitis; HCC, hepatocellular carcinoma; AIH, autoimmune hepatitis; CYP2D6, cytochrome P450 2D6; LKM-1, type 1 liver/kid
Metabolic and immune impairments induced by the endocrine disruptors benzo[a]pyrene and triclosan in Xenopus tropicalis
Keywords: بیماری کبد چرب غیرالکلی; Amphibian; Xenopus tropicalis; Endocrine disruptors; Metabolism; NAFLD; benzo[a]pyrene; Triclosan
Dihydromyricetin ameliorates oleic acid-induced lipid accumulation in L02 and HepG2 cells by inhibiting lipogenesis and oxidative stress
Keywords: بیماری کبد چرب غیرالکلی; Dihydromyricetin; NAFLD; Apoptosis; Lipid accumulation; Oxidative stress