Keywords: AAPH; 2; 2â²-azo-bis (2-amidinopropane) dihydrochloride; cNOS; constitutive nitric oxide synthase; iNOS; inducible nitric oxide synthase; L-NAME; NG-nitro-l-arginine methyl ester; ROM; reactive oxygen metabolites; SNP; sodium nitroprusside;
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Keywords: E171; Titanium dioxide; Nanoparticles; Vasoconstriction; Endothelial dysfunction; 5-HT; 5-hydroxytryptamine; 5-HT1B; 5-hydroxytryptamine receptor 1B; 5-HT2A; 5-hydroxytryptamine receptor 2A; EDNRA; endothelin receptor A; EDNRB; endothelin receptor B; ICAM
Keywords: arginase; nitric oxide synthase; reactive oxygen species; red blood cells; type 2 diabetes; ABH; 2 (S)-amino-6-boronohexanoic acid; dP/dt; the first derivative of left ventricular pressure; eNOS; endothelial nitric oxide synthase; iNOS; inducible isoform
Keywords: PGMO; Pre-gestational maternal obesity; PGMN; Pre-gestational maternal normal weight; HUVECs; Human umbilical vein endothelial cells; NO; Nitric oxide; NOS; Nitric oxide synthase; eNOS; endothelial nitric oxide synthase; Akt; Protein kinase B/Akt; ER; end
Keywords: CVC; cutaneous vascular conductance; %CVCmax; percentage of maximum cutaneous vascular conductance; EDHF; endothelium derived hyperpolarizing factor; L-NAME; NG-nitro-l-arginine methyl ester; NO; nitric oxide; SNP; sodium nitroprusside; TRPV3; transient r
Keywords: NG-Nitro-l-arginine methyl ester; 7-Nitroindazole; Malathion; Oxidative stress; Cholinesterases; Comet assay;
Keywords: Ach; acetylcholine; CG; coeliac ganglion; E2; estradiol; eNOS; endothelial nitric oxide syntase; iNOS; inducible nitric oxide syntase; l-NAME; NG-nitro-l-arginine methyl ester; NO; nitric oxide; P; progesterone; PE; proestrous; PNS; peripheral nervous sys
Keywords: 2K-1C; two-kidney one-clip; ACE-Is; angiotensin converting enzyme inhibitors; AL; aliskiren; Ang II; angiotensin II; ANP; atrial natriuretic peptide; APTT; activated partial thromboplastin time; ARBs; AT1 receptor antagonists; ASA; aspirin; Fg; fibrinogen
Keywords: LCAT; lecithin:cholesterol acyltransferase; HDL; high density lipoproteins; NA; noradrenaline; ACh; acetylcholine; L-NAME; NG-nitro-l-arginine methyl ester; SNP; Sodium nitroprusside; NO; nitric oxide; eNOS; endothelial NO synthase; LcatKO; LCAT knockout
Keywords: AD; Alzheimer's disease; ALD; X-linked adrenoleukodystrophy; ALDRP; adrenoleukodystrophy-related protein; ALDP; adrenoleukodystrophy protein; ALS; amyotrophic lateral sclerosis; ATF-2; activating transcription factor 2; BBB; blood-brain barrier; AP-1; a
Keywords: hAECs; human aortic endothelial cells; oxLDL; oxidized low-density lipoprotein; nLDL; native low-density lipoprotein; GPX; glutathione peroxidase; IGF-1; insulin-like growth factor 1; Apoe; apolipoprotein e; ROS; reactive oxygen species; l-NAME; NG-nitro-
Intracellular acidification reduces l-arginine transport via system y+L but not via system y+/CATs and nitric oxide synthase activity in human umbilical vein endothelial cells
Keywords: pHo; extracellular pH; pHi; intracellular pH; 4F2hc; heavy chain of the cell surface antigen 4F2; HUVECs; human umbilical vein endothelial cells; HPAEC; human pulmonary artery endothelial cells; RAEC; rat aorta endothelial cells; hENT1/2; human equilibrat
Formaldehyde regulates vascular tensions through nitric oxide-cGMP signaling pathway and ion channels
Keywords: Formaldehyde; Thoracic aorta ring; Vascular tension; Ion channels; Signal pathway; 4-AP; 4-aminopyridine; ACh; acetylcholine; l-NAME; NG-nitro-l-arginine methyl ester; ACE; angiotensin-converting enzyme; VSMCs; vascular smooth muscle cells; BKCa; big-cond
Acetone fraction from Sechium edule (Jacq.) S.w. edible roots exhibits anti-endothelial dysfunction activity
Keywords: Ab; antibody; AGII; angiotensin II; AT1R; angiotensin II receptor type 1; AT2R; angiotensin II receptor type 2; BHA; branch of hepatic artery; CMC; carboxymethylcellulose; DAP; diastolic arterial pressure; DHE; dihydroethidium oxidation; ED; endothelial d
Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats
Keywords: MeCO; methanolic root extract of Colebrookea oppositifolia; I/R; ischemia reperfusion; DPPH; 2, 2-diphenyl-L-picrylhydrazyl; FRAP; ferric reducing antioxidant power; ORAC; oxygen radical absorbance capacity; LPS; lipopolysaccharide; LC-MS/MS; liquid chrom
Evidence of a role for spinal HMGB1 in ischemic stress-induced mechanical allodynia in mice
Keywords: CPSP; central post-stroke pain; HMGB1; high-mobility group box-1; BCAO; bilateral carotid artery occlusion; mAb; monoclonal antibody; LMWH; low-molecular-weight heparin; LPS-RS; lipopolysaccharides from the photosynthetic bacterium Rhodobacter sphaeroides
Tetrahydrobiopterin Role in human umbilical vein endothelial dysfunction in maternal supraphysiological hypercholesterolemia
Keywords: MPH; maternal physiological hypercholesterolemia; MSPH; maternal supraphysiological hypercholesterolemia; GTP; guanosine triphosphate; GTPCH1; GTP cyclohydrolase 1; DHFR; dihydrofolate reductase; BH2; dihydrobiopterine; BH4; tetrahydrobiopterine; HUVECs;
Labetalol, nebivolol, and propranolol relax human radial artery used as coronary bypass graft
Keywords: 16; 23; CABG; coronary artery bypass grafting; Emax; maximum relaxant effect; L-NAME; NG-nitro-L-arginine methyl ester; NO; nitric oxide; RA; radial artery; TEA; tetraethyl ammonium;
Hyperoxic gassing with Tiron enhances bradykinin-induced endothelium-dependent and EDH-type relaxation through generation of hydrogen peroxide
Keywords: CPA; cyclopiazonic acid; EDH; endothelium-derived hyperpolarization; EDRF; endothelium-derived relaxing factor; H2O2; hydrogen peroxide; l-NAME; NG-nitro-l-arginine methyl ester; PCAs; porcine coronary arteries; ROS; reactive oxygen species; SOD; superoxi
Gender specific generation of nitroxyl (HNO) from rat endothelium
Keywords: ACh; acetylcholine; AS; Angeli's salt; BH4; tetrahydrobiopterin; DEA/NO; diethylamine NONOate; EC; endothelial cell; eNOS; endothelial nitric oxide synthase; GSH; glutathione; HNO; nitroxyl; l-NAME; NG-nitro-l-arginine methyl ester; NO; nitric oxide radic
Heme oxygenase-1-derived bilirubin protects endothelial cells against high glucose-induced damage
Keywords: BAEC; bovine aortic endothelial cells; Bil; bilirubin; DCF-DA; 2,7-dichlorofluorescin diacetate; HO-1; heme oxygenase-1; L-NAME; NG-nitro-L-arginine methyl ester; MTT; 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide; Nrf2; nuclear factor ery
Des-aspartate angiotensin I (DAA-I) reduces endothelial dysfunction in the aorta of the spontaneously hypertensive rat through inhibition of angiotensin II-induced oxidative stress
Keywords: ACE; angiotensin converting enzyme; AT1R; angiotensin II type 1 receptor; AT2R; angiotensin II type 2 receptor; cGMP; cyclic guanosine monophosphate; DAA-I; Des- aspartate angiotensin I; DAG; diacylgylcerol; EDCF; endothelium-derived contracting factor; E
Gallic acid isolated from Spirogyra sp. improves cardiovascular disease through a vasorelaxant and antihypertensive effect
Keywords: GA; gallic acid; CVD; cardiovascular disease; NO; nitric oxide; HUVECs; human umbilical vein endothelial cells; l-NAME; NG-nitro-l-arginine methyl ester; ACE; angiotensin-I converting enzyme; SHR; spontaneously hypertensive rats; Gallic acid; Spyrogira sp
Sex differences in the role of transient receptor potential (TRP) channels in endothelium-dependent vasorelaxation in porcine isolated coronary arteries
Keywords: A23187; calcium ionophore; ACA; 2-[3-(4-pentylphenyl)prop-2-enoylamino]benzoic acid; EDH; endothelium-derived hyperpolarization; H2O2; hydrogen peroxide; L-NAME; NG-nitro-L-arginine methyl ester; PCAs; porcine coronary arteries; Pyr3; ethyl 1-[4-(trichlor
Effects of d-penicillamine on pentylenetetrazole-induced seizures in mice: Involvement of nitric oxide/NMDA pathways
Keywords: NO; nitric oxide; d-Pen; d-penicillamine; l-NAME; NG-nitro-l-arginine methyl ester; 7-NI; 7-nitroindazole; NOS; nitric oxide synthase; NMDA; N-methyl-d-aspartate; d-Penicillamine; Nitric oxide; Nitric oxide synthase inhibitors; Pentylenetetrazole; Seizure
Tributyltin contributes in reducing the vascular reactivity to phenylephrine in isolated aortic rings from female rats
Keywords: l-NAME; NG-Nitro-l-Arginine Methyl Ester; TBT; tributyltin; PHE; phenylephrine; ACh; acetylcholine; SNP; sodium nitroprusside; CONT; Control; NO; nitric oxide; TEA; tetraethylammonium; SR; sarcoplasmic reticulum; OTCs; Organotin compounds; ROS; reactive o
Cyclooxygenase metabolism mediates vasorelaxation to 2-arachidonoylglycerol (2-AG) in human mesenteric arteries
Keywords: 2-AG; 2-arachidonoylglcerol; AEA; anandamide; ANOVA; analysis of variance; CB1; cannabinoid receptor one; CB2; cannabinoid receptor two; COX-1; cyclooxygenase one; COX-2; cyclooxygenase two; ECS; endocannabinoid system; FAAH; fatty acid amide hydrolase; K
Formation, signaling functions, and metabolisms of nitrated cyclic nucleotide
Keywords: cGMP; guanosine 3â²,5â²-cyclic monophosphate; GTP; guanosine 5â²-triphosphate; pGC; particulate-type guanylyl cyclase; sGC; soluble-type guanylyl cyclase; 8-Nitro-cGMP; 8-nitroguanosine 3â²,5â²-cyclic monophosphate; PTM; post-translational modificati
The effect of inorganic arsenic on endothelium-dependent relaxation: Role of NADPH oxidase and hydrogen peroxide
Keywords: ACh; acetylcholine; CPA; cyclopiazonic acid; DHE; dihydroethidium; ER; endoplasmic reticulum; KCa; calcium-activated K+ channels; NO; nitric oxide; H2O2; hydrogen peroxide; L-NAME; NG-nitro-L-arginine methyl ester; O2â¢â; superoxide anion; PE; phenylep
Reduced angiotensin II levels cause generalized vascular dysfunction via oxidant stress in hamster cheek pouch arterioles
Keywords: ACE; angiotensin converting enzyme; ACh; acetylcholine; ANG II; angiotensin II; ARB; angiotensin receptor blocker; AT1; angiotensin II type 1 receptor; cGMP; cyclic guanosine monophosphate; Cu/Zn SOD; copper zinc (intracellular) superoxide dismutase; DHE;
Effects of NOS inhibitors on the benzodiazepines-induced memory impairment of mice in the modified elevated plus-maze task
Keywords: Benzodiazepines; Spatial memory; Modified elevated plus maze; NG-nitro-l-arginine methyl ester; 7-nitroindazole; Mice
Sustained activation of AMPK ameliorates age-associated vascular endothelial dysfunction via a nitric oxide-independent mechanism
Keywords: ACh; acetylcholine; AICAR; aminoimidazole carboxamide ribonucleotide; AMPK; adenosine monophosphate protein kinase; COX; cyclooxygenase; CVD; cardiovascular disease; EDD; endothelium dependent dilation; EDHF; endothelial derived hyperpolarizing factor; l-
Endothelial Nitric Oxide Synthase Expression in Postmenopausal Women: A Sex-Specific Risk Factor in Coronary Surgery
Keywords: CABG; coronary artery bypass graft surgery; eNOS; endothelium-derived nitric oxide synthase; IMA; internal mammary artery; L-NAME; nG-nitro-L-arginine methyl ester; mRNA; messenger ribonucleic acid; NO; nitric oxide; PCR; polymerase chain reaction; qRT-PC
Polysaccharide fractions of Caesalpinia ferrea pods: Potential anti-inflammatory usage
Keywords: ALT; alanine transaminase; AST; aspartate transaminase; AUC; area under curves; BSA; bovine serum albumin; TPL; total polysaccharides; fMLP; N-formyl-methionyl-leucyl phenylalanine; HE; hematoxylin-eosin; l-NAME; NG-nitro-l-arginine methyl ester; NO; ni
Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: role of nitric oxide and reactive oxygen species
Keywords: I/RP; ischemia/reperfusion; EC; endothelial cell; mtROS; mitochondrial reactive oxygen species; H/RO; hypoxia/reoxygenation; Drp1; dynamin-related protein 1; O2â¢â; superoxide; eNOS; endothelial nitric oxide synthase; ETC; electron transport chain; ONO
Nicotine improves ethanol-induced impairment of memory: Possible involvement of nitric oxide in the dorsal hippocampus of mice
Keywords: ANOVA; analysis of variance; CA1; field CA1 of the hippocampus; ETOH; ethanol; GMP; guanosine monophosphate; L-NAME; NG-nitro-l-arginine methyl ester; MK-801; Dizocilpine or (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H dibenzo[a,d]cyclohepten -5,10-imine hydrog
Ethanol induces vascular relaxation via redox-sensitive and nitric oxide-dependent pathways
Keywords: NO; Nitric oxide; eNOS; endothelial NO synthase; nNOS; neuronal NO synthase; ROS; reactive oxygen species; ([Ca2Â +]c); Cytosolic calcium concentration; ADH; alcohol dehydrogenase; ([NO]c); Cytosolic NO concentration; VSMCs; vascular smooth muscle cells;
Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension
Keywords: Ang II; angiotensin II; DAPI; 4,6-diamidino-2-phenylindole dichlorohydrate; DHE; dihydroethidium; DOCA; deoxycorticosterone acetate; DPI; diphenylene iodonium; eNOS; endothelial nitric oxide synthase; ET-1; endothelin-1; GCLC; γ-glutamylcysteine syntheta
Nitric oxide - A versatile key player in cochlear function and hearing disorders
Keywords: ABR; auditory brainstem response; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATP; adenosine triphosphate; DAF; 4,5-diaminofluorescein diacetate; dB; decibel; eNOS; endothelial nitric oxide synthase; EP; endocochlear potential; FAD; flavi
Activation of peroxisome proliferator-activated receptor-β/-δ (PPARβ/δ) prevents endothelial dysfunction in type 1 diabetic rats
Keywords: ACh; acetylcholine; CPT-1; carnitine palmitoyltransferase 1; DAPI; 4,6-diamidino-2-phenylindole dichlorohydrate; DHE; dihydroethidium; eNOS; endothelial NO synthase; EDHF; endothelium-derived hyperpolarizing factor; HR; heart rate; MCP-1; monocyte chemoat
Potent vasodilation effect of amurensin G is mediated through the phosphorylation of endothelial nitric oxide synthase
Keywords: ACC; acetyl-CoA carboxylase; ACh; acetylcholine; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; AMPK; adenosine 5â²-monophosphate-activated protein kinase; CA-AMPK; constitutive active AMPK; CaMK II; calmodulin-dependent protein kinase II;
Bacopa monnieri and its constituents is hypotensive in anaesthetized rats and vasodilator in various artery types
Keywords: PE; phenylephrine; E; endothelium; L-NAME; NG-nitro-l-arginine methyl ester; ACh; acetylcholine; SR; sarcoplasmic reticulum; Bacopa monnieri; Blood pressure; Artery; Vasodilation; Calcium;
Lack of heterologous receptor desensitization induced by angiotensin II type 1 receptor activation in isolated normal rat thoracic aorta
Keywords: RAS; renin-angiotensin system; ANG II; angiotensin II; AT1; angiotensin II type 1; AT2; angiotensin II type 2; GPCR; G-protein coupled receptors; BK; bradykinin; NO; nitric oxide; cGMP; cyclic guanosin monophosphate; L-NAME; NG-nitro-l-arginine methyl e
6-Methylnitroarachidonate: A novel esterified nitroalkene that potently inhibits platelet aggregation and exerts cGMP-mediated vascular relaxation
Keywords: NO; nitric oxide; AAMet; methylarachidonic acid; AAMetNO2; methylnitroarachidonate; 6-AAMetNO2; 6-methylarachidonate; AA; arachidonic acid; MS; mass spectrometry; IR; infrared radiation; NMR; nuclear magnetic resonance; cGMP; cyclic guanosine monophosphat
Effects of endokinin A/B, endokinin C/D, and endomorphin-1 on the regulation of mean arterial blood pressure in rats
Keywords: Endokinin A/B; Endokinin C/D; Endomorphin-1; SR140333B; SR48968C; SR142801; NG-nitro-l-arginine methyl ester
The systemic inhibition of nitric oxide production rapidly regulates TRH mRNA concentration in the paraventricular nucleus of the hypothalamus and serum TSH concentration. Studies in control and cold-stressed rats
Keywords: PVN; paraventricular nucleus of the hypothalamus; TRH; thyrotropin releasing hormone; NO; nitric oxide; TSH; thyrotropin; l-NAME; NG-nitro-l-arginine methyl ester; AVP; arginine vasopressin; OT; oxytocin; NOS; nitric oxide synthase; HPT; hypothalamus-pi
Transient Receptor Potential Ankyrin 1 Is Expressed by Inhibitory Motoneurons of the Mouse Intestine
Keywords: Enteric Nervous System; TRP Channels; Motility; AITC; allyl isothiocyanate; CCh; carbachol; CMA; cinnamaldehyde; GE; gastric emptying; IR; immunoreactivity; 4-HNE; 4-hydroxynonenal; l-NAME; NG-nitro-l-arginine methyl ester; NOS; nitric oxide synthase; SIT
Basal nitric oxide release attenuates cell migration of HeLa and endothelial cells
Keywords: 8-Br-cGMP; 8-bromoguanosine 3â²,5â²-cyclic monophosphate; DETA-NO; 2,2â²-(hydroxynitrosohydrazino)bis-ethanamine; DOX; doxicycline; ECs; endothelial cells; eNOS; endothelial nitric oxide synthase; FBS; fetal bovine serum; HUVECs; Human Umbilical Vein
Putative antinociceptive action of nitric oxide in the caudal part of the spinal trigeminal nucleus during chronic carrageenan-induced arthritis in the rat temporomandibular joint
Keywords: AD; articular disc; AC; anaesthetic control; BH4; tetrahydrobiopterin; CaM; calmodulin; CFA; complete Freund's adjuvant; cGMP; cyclic guanosine monophosphate; CIA; carrageenan-induced arthritis; CNS; central nervous system; Cuf; cuneate fascicle; DAB; 3,3
Nitric oxide synthase inhibitor attenuates the anorexigenic effect of corticotropin-releasing hormone in neonatal chicks
Keywords: Corticotropin-releasing hormone; Feeding; Intracerebroventricular injection; NG-nitro-l-arginine methyl ester; Neonatal chicks; Neuropeptide Y; Nitric oxide