Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; Hypoxia inducible factor-1α; NF-E2-related factor 2; Seven in absentia homolog 2; Hypoxia; Oxidative stressHIF-1α, hypoxia inducible factor-1α; PHD, prolyl hydroxylase domain-containing protein; MafG, small Maf protein G; Nrf2, NF-E2-related factor 2; Kea
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Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; Sb, Antimony; NAC, N-acetylcysteine; Nrf2, NF-E2-related factor 2; ROS, Reactive oxygen species; Sb2O3, Antimony trioxide; TBHQ, Tertiary butylhydroquinoneAntimony; Apoptosis; Nrf2; Gadd45b; ROS
Anthocyans-rich Aronia melanocarpa extract possesses ability to protect endothelial progenitor cells against angiotensin II induced dysfunction
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; Chokeberry; Aronia melanocarpa; Endothelial progenitor cells; Oxidative stress; Angiotensin II, Heme oxygenase-1EPC, endothelial progenitor cells; Ang II, angiotensin II; Nrf2, NF-E2-related factor 2; HO-1, heme oxygenase-1; AME, Aronia melanocarpa extrac
The Role of Nrf2 in Migration and Invasion of Human Glioma Cell U251
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; Glioma; Invasion; Matrix metalloproteinase 9; Migration; NF-E2-related factor 2ARE, antioxidant response element; DMEM, Dulbecco's modified Eagle medium; MMP9, Matrix metalloproteinase 9; Nrf2, NF-E2-related factor 2; RT-PCR, Reverse transcriptase–polymer
Sulforaphane attenuates hepatic fibrosis via NF-E2-related factor 2-mediated inhibition of transforming growth factor-β/Smad signaling
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; SFN, DL-sulforaphane; Nrf2, NF-E2-related factor 2; TGF-β, transforming growth factor-β; BDL, bile duct ligation; TIMP-1, tissue inhibitor of matrix metalloproteinase-1; PAI-1, plasminogen activator inhibitor-1; ECM, extracellular matrix; HSC, hepatic ste
Autophagy in cancer: Having your cake and eating it
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; LC3, microtubule-associated protein 1 light chain 3; OIS, oncogene-induced senescence; PI3K, phosphoinositide 3-kinase; mTOR, mammalian target of rapamycin; PTEN, phosphatase and tensin homolog; NRF2, NF-E2-related factor 2; HDF, human diploid fibroblasts
Sulforaphane prevents microcystin-LR-induced oxidative damage and apoptosis in BALB/c mice
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; MCs, microcystins; MC-LR, microcystin-LR; SFN, sulforaphane; Nrf2, NF-E2-related factor 2; ROS, reactive oxygen species; GSH, glutathione; CMZ, chlomethiazole; DAS, diallyl sulfide; DMSO, dimethyl sulfoxide; PBS, phosphate-buffered saline; ELISA, immunoso
Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; AhR, aryl hydrocarbon receptor; BNF, β-naphthoflavone; DEN, N-diethylnitrosamine; DIM, 3,3′-diindolylmethane; GST-P, glutathione S-transferase placental form; I3C, indole-3-carbinol; Nrf2, NF-E2-related factor 2; PCB,
A comparative integrated transcript analysis and functional characterization of differential mechanisms for induction of liver hypertrophy in the rat
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; AhR, Aryl hydrocarbon Receptor; CAR, Constitutive Androstane Receptor; Cyp, Cytochrome P450; FA, fatty acid; LH, liver hypertrophy; Nrf2, NF-E2-related factor 2; PP, Peroxisome Proliferator; PPAR, Peroxisome Proliferator Activated Receptor; PXR, Pregnane
Simvastatin lowers reactive oxygen species level by Nrf2 activation via PI3K/Akt pathway
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; HMG-CoA, 3-hydroxy-3-methyl-glutaryl-CoA; Nrf2, NF-E2-related factor 2; ROS, reactive oxygen species; Keap1, Kelch-like ECH associating protein; ARE, antioxidant response element; FBS, fetal bovine serum; MEF, mouse embryonic fibroblast; WT, wild type; KO
Nrf2/HO-1 signaling pathway may be the prime target for chemoprevention of cisplatin-induced nephrotoxicity by lycopene
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; ARE, antioxidant response element; CAT, catalase; GPx, glutathione peroxidase; HO-1, heme oxygenase-1; NF-κB p65, nuclear factor kappa B; Nrf2, NF-E2-related factor 2; NP-40, nonidet P-40; PMSF, phenylmethylsulfonyl-fluoride; ROS, reactive oxygen species;
Cochlear protection from acoustic injury by inhibitors of p38 mitogen-activated protein kinase and sequestosome 1 stress protein
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; p38 MAPK; sequestosome 1; p62; A170; acoustic injury; cochleaABR, auditory brainstem response; JNK, c-Jun NH2-terminal kinase; Nrf2, NF-E2-related factor 2; p38 MAPK, p38 mitogen-activated protein kinase
Genistein as a neuroprotective antioxidant attenuates redox imbalance induced by β-amyloid peptides 25–35 in PC12 cells
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; GEN, genistein; Aβ, β-amyloid peptides; AD, Alzheimer's disease; GSH/GSSG, reduced glutathione/oxidized glutathione; Nrf2, NF-E2-related factor 2; HO-1, heme oxygenase-1; γ-GCS, γ-glutamylcysteine synthetase; ARE, antioxidant response element; GSH, glutat
Effects of 4-phenylbutyric acid on the process and development of diabetic nephropathy induced in rats by streptozotocin: Regulation of endoplasmic reticulum stress-oxidative activation
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; 4-PBA, 4-phenylbutyric acid; DN, diabetic nephropathy; ER, endoplasmic reticulum; SD, Sprague–Dawley; STZ, streptozotocin; p-IRE1α, phosphorylation of inositol-requiring enzyme-1α; NT, nitrotyrosine; Nrf2, NF-E2-related factor 2; MDA, malondialdehyde; SOD
Sulforaphane protects Microcystin-LR-induced toxicity through activation of the Nrf2-mediated defensive response
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; MCs, Microcystins; MC-LR, Microcystin-LR; SFN, Sulforaphane; PLC, Primary Liver Cancer; Nrf2, NF-E2-related factor 2; GSH, Glutathione; ARE, antioxidant response element; ALT, Alanine aminotransferase; ITC, isothiocyanate; NQO1, NAD(P)H:quinone oxidoreduc
Targeting NRF2 signaling for cancer chemoprevention
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; NRF2, NF-E2-related factor 2; KEAP1, Kelch-like ECH-associated protein 1; GSTs, Glutathione S-transferases; NQO1, NAD(P)H quinine oxidoreductases; UGTs, UDP-glucuronosyl transferases; ROS, reactive oxygen species; DMBA, 7, 12-dimethylbenz[a]anthracene; TP
Nrf2:INrf2 (Keap1) signaling in oxidative stress
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; ARE, antioxidant-response element; BTB, broad complex, tramtrack, bric-a-brac; Nrf2, NF-E2-related factor 2; INrf2, inhibitor of Nrf2, also known as Keap1; ROS, reactive oxygen speciesNrf2; INrf2; Keap1; Antioxidant response element; Regulation of gene ex
Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; Prdx, peroxiredoxin; ARE, antioxidant-responsive element; t-BHQ, tert-butylhydroquinone; Nrf2, NF-E2-related factor 2; Nrf3, NF-E2-related factor 3; Keap1, Kelch-like ECH-associated protein 1; siRNA, short interfering RNA; ChIP, chromatin immunoprecipitat
β-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; BNF, β-naphthoflavone; AhR, aryl hydrocarbon receptor; DEN, N-diethylnitrosamine; GST-P, glutathione S-transferase placental form; qRT-PCR, quantitative real-time RT-PCR; Nrf2, NF-E2-related factor 2; ROS, reactive oxygen species; 8-OHdG, 8-hydroxydeoxygu
HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells
Keywords: Nrf2، فاکتور 2 مربوط به NF-E2; Anti-oxidants; Bach 1; Gene expression; Heme; Heme oxygenase; Hepatitis C virus; Oxidative stressAP, activator protein; ARE, anti-oxidant response element; HCV, hepatitis C virus; HO, heme oxygenase; Nrf2, NF-E2-related factor 2; NS, nonstructural; ROS, r