Keywords: MAP; Antibodies; NS4B; Dengue virus
مقالات ISI (ترجمه نشده)
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K48-linked polyubiquitination of dengue virus NS1 protein inhibits its interaction with the viral partner NS4B
Keywords: Dengue virus; NS1; NS4B; Ubiquitination; K48-linked polyubiquitin; Deubiquitinase; Proteasome;
Codon usage variation of Zika virus: The potential roles of NS2B and NS4A in its global pandemic
Keywords: ZIKV; Zika virus; NS1; non-structural protein NS1; E; envelope protein; NS3; non-structural protein NS3; C; anchored capsid protein; prM; membrane glycoprotein precursor; NS2A; non-structural protein NS2A; NS2B; non-structural protein NS2B; NS4A; non-stru
Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit
Keywords: Dengue virus; NS4B; Cell-based screen; Scaffold morphing; 2-Oxopiperazine;
Characterization of a dengue NS4B inhibitor originating from an HCV small molecule library
Keywords: Dengue; Non-structural protein 4B; NS4B; Antiviral compound; HCV; RLuc; Renilla luciferase; 2â²CMC; 2â²-C-methylcytidine;
Discovery of 2-(4-sulfonamidophenyl)-indole 3-carboxamides as potent and selective inhibitors with broad hepatitis C virus genotype activity targeting HCV NS4B
Keywords: CQDSXYOVMHALPF-UHFFFAOYSA-N; OBULGMCFXOTNNK-ZDUSSCGKSA-N; DUGHOSNYUCLBTI-UHFFFAOYSA-N; HCV inhibitor; Replicon; 2-(4-Sulfonamidophenyl)-indole 3-carboxamides; NS4B;
Heterogeneous genomic locations within NS3, NS4A and NS4B identified for genotyping and subtyping of Hepatitis C virus: A simple genome analysis approach
Keywords: bs; bootstrap; GTR; general time reversible; HCV; Hepatitis C virus; MCL; maximum composite likelihood; ML; maximum likelihood; N-J; neighbor-joining; RA; reference alignment; SVR; sustained virological response; HCV; Genotyping; Subtyping; Phylogenetic a
Inhibition of HCV replication by humanized-single domain transbodies to NS4B
Keywords: Direct acting anti-HCV; Hepatitis C virus; Humanized-nanobody; NS4B; Transbody; qRT-PCR;
Targeting dengue virus NS4B protein for drug discovery
Keywords: Flavivirus; Dengue; Nonstructural protein 4B; NS4B; Antivirals
Autophagy and proteins involved in vesicular trafficking
Keywords: AMD; age-related macular degeneration of the eye; AMPK; AMP-activated protein kinase; ATG; autophagy-related protein; CMA; chaperone-mediated autophagy; COPII; coat protein complex II; DFCP1; double FYVE domain-containing protein 1; EGF; epidermal growth
6-(Azaindol-2-yl)pyridine-3-sulfonamides as potent and selective inhibitors targeting hepatitis C virus NS4B
Keywords: SNKXAUJPUHFFKN-NSHDSACASA-N; ZLGQGMUTVCQNFC-NSHDSACASA-N; HCV inhibitors; Replicon; 6-(Azaindol-2-yl)pyridine-3-sulfonamides; Structure-activity relationship; NS4B;
Secondary structure and membrane topology of dengue virus NS4B N-terminal 125 amino acids
Keywords: Dengue virus; Membrane protein; NMR; Paramagnetic relaxation enhancement; NS4B;
Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein
Keywords: NS4B; Hepatitis C virus (HCV); Replication inhibitors; Spirocyclic ketals; Pyrazolo[1,5-a]pyridine
Research ArticleHepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity
Keywords: HCV; hepatitis C virus; PAMP; pathogen-associated molecular pattern; STING; stimulator of interferon genes; MITA; mediator of IRF3 activation; SeV; Sendai virus; ER; endoplasmic reticulum; Hepatitis C virus; Interferon; NS4B; STING/MITA; TBK-1;
Discovery of novel HCV inhibitors: Synthesis and biological activity of 6-(indol-2-yl)pyridine-3-sulfonamides targeting hepatitis C virus NS4B
Keywords: HCV inhibitors; Replicon; 6-(Indol-2-yl)pyridine-3-sulfonamides; NS4B;
Development and characterization of a replicon-based phenotypic assay for assessing HCV NS4B from clinical isolates
Keywords: HCV; NS4B; Chimeric replicon; Clinical isolates;
HCV NS4B induces apoptosis through the mitochondrial death pathway
Keywords: Hepatitis C virus; NS4B; Apoptosis; Mitochondrial death pathway; Cytochrome c;
The membrane spanning domains of protein NS4B from hepatitis C virus
Keywords: NS4B; HCV; Pre-transmembrane domain;
Interaction with membranes of the full C-terminal domain of protein NS4B from Hepatitis C virus
Keywords: 5-NS; 5-doxyl-stearic acid; 16-NS; 16-doxyl-stearic acid; 14BMP; bis(monomyristoylglycero)phosphate; 18BMP; bis(monooleoylglycero)phosphate; BPI; bovine brain l-α-phosphatidylinositol; BPS; bovine brain l-α-phosphatidylserine; CF; 5-carboxyfluorescein;
Evaluation of core and NS4B synthetic peptide-based immunoassays for the detection of hepatitis C virus antibodies in clinical samples from Cameroon, Central Africa
Keywords: Hepatitis C; Core; NS4B; Peptides; Antibodies; Cameroon
A small molecule inhibits HCV replication and alters NS4B's subcellular distribution
Keywords: HCV; Inhibitor; NS4B; Amphipathic helix
A comparative analysis of the substrate permissiveness of HCV and GBV-B NS3/4A proteases reveals genetic evidence for an interaction with NS4B protein during genome replication
Keywords: Hepacivirus; Hepatitis C virus; GB virus B; Protease; Substrate specificity; Replication; Mutagenesis; Structural model; NS3; NS4B
Identification of the nonstructural protein 4B of hepatitis C virus as a factor that inhibits the antiviral activity of interferon-alpha
Keywords: IFN-alpha resistance; Hepatitis C virus; NS4B
Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-κB activation
Keywords: Hepatitis C virus; NS4B; UPR; EOR; ROS; Ca2+; NF-κB; IκBα; Liver pathogenesis; Signal transduction pathways
Formation and function of hepatitis C virus replication complexes require residues in the carboxy-terminal domain of NS4B protein
Keywords: HCV; NS4B; NS3; NS5A; Subcellular localization; Membrane-association; Replication complex; Membranous web
Structural and functional comparison of the non-structural protein 4B in flaviviridae
Keywords: In silico analysis; Flaviviridae; NS4B; Leucine zipper; Structure model
A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesis
Keywords: West Nile virus; NS4B; Flavivirus replication