Keywords: کیناز فعال p21; Actin dynamics; Rho GTPases; dendritic spines; postsynapse; Abi-1; Abelson interacting protein 1; Abp1; actin binding protein 1; ACTN4; α-actinin-4; ADF; actin-depolymerizing factor; ADHD; attention deficit/hyperactivity disorder; ADNP; activity-dependen
مقالات ISI کیناز فعال p21 (ترجمه نشده)
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Keywords: کیناز فعال p21; Di-n-butyl phthalate (DBP); Neuroplasticity; Rho-GTPase; ANOVA; analysis of variance; BBP; benzyl butyl phthalate; CREB; cyclic adenosine monophosphate response element binding protein; DBP; di-n-butyl phthalate; DiBP; diisobutyl phthalate; DEHP; di(2-eth
Label-free quantitative phosphoproteomic profiling of cellular response induced by an insect cytokine paralytic peptide
Keywords: کیناز فعال p21; PP; Paralytic peptide; LC-MS/MS; liquid chromatography-tandem mass spectrometry; TFs; transcription factors; PKs; protein kinases; KEGG; Kyoto Encyclopedia of Genes and Genomes; MAPK; mitogen-activated protein kinase; PAK; p21-activated kinase; GBP; growt
Keywords: کیناز فعال p21; EC; endothelial cells; HPAEC; human pulmonary artery endothelial cells; HLMVEC; human lung microvascular endothelial cells; MLC; myosin light chain; MYPT; myosin-associated phosphatase; PAK1; p21-activated kinase;
Keywords: کیناز فعال p21; AGEs; advanced glycation end products; BSA; bovine serum albumin; LLC-PK1; porcine kidney proximal tubule epithelial cells; HK2; human kidney proximal tubule epithelial cells; SFM; serum-free medium; GM; growth medium; PIP5Kγ; phosphatidylinositol 4-phos
Keywords: کیناز فعال p21; Aggrecan; Axon regeneration; Dystrophic endball; Optic nerve; p21-activated kinase; Paxillin; Point contact; Protein kinase A;
Keywords: کیناز فعال p21; Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange
Relevance of small GTPase Rac1 pathway in drug and radio-resistance mechanisms: Opportunities in cancer therapeutics
Keywords: کیناز فعال p21; GEF; Guanine Exchange Factor; GAP; GTPase-activating protein; EGF; epidermal growth factor; PDGF; platelet-derived growth factor; EGFR; epidermal growth factor receptor; Pak; p21-activated kinase; EMT; epithelial to mesenchymal transition; SCC; squamous c
Nanobodies targeting cortactin proline rich, helical and actin binding regions downregulate invadopodium formation and matrix degradation in SCC-61 cancer cells
Keywords: کیناز فعال p21; Abl; ableson kinase; ABR; actin binding repeat; Arg; ableson related gene kinase; Arp2/3; actin related protein 2/3; ATAT1; alpha-tubulin N-acetyltransferase 1; DMEM; Dulbecco's modified Eagle's medium; DOX; doxycycline; Erk; extracellular signal-re
Tubulin-dependent secretion of S100A6 and cellular signaling pathways activated by S100A6-integrin β1 interaction
Keywords: کیناز فعال p21; BSA; bovine serum albumin; CCCP; carbonyl cyanide chlorophenylhydrazone; DPBS; Dulbecco's Phosphate Buffered Saline; DTT; dithiothreitol; EGFR; epidermal growth factor receptor; FAK; focal adhesion kinase; GSK3β; glycogen synthase kinase-3β; ILK; integr
Loss of p21-activated kinase 1 (Pak1) promotes atrial arrhythmic activity
Keywords: کیناز فعال p21; Atrial fibrillation; Excitation-contraction coupling; NADPH oxidase-2; p21-activated kinase; Reactive oxygen species;
EphBs and ephrin-Bs: Trans-synaptic organizers of synapse development and function
Keywords: کیناز فعال p21; βGal; β-Galactosidase; Aβ; amyloid-β; Abl; Abelson murine leukemia viral oncogene homolog; AD; Alzheimer's disease; AMPAR; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; APP; amyloid precursor protein; BLA; basolateral amygdala; CaMKI
Paving the Rho in cancer metastasis: Rho GTPases and beyond
Keywords: کیناز فعال p21; ADP; adenosine diphosphate; AMP; adenosine monophosphate; AMT; amoeboid-mesenchymal transition; APC; adenomatosis polyposis coli; Arp2/3; actin related protein 2/3; Cdc42; cell division control protein 42 homolog; CK1; casein kinase 1; COX-2; cyclooxygena
p21-activated kinase 4 regulates HIF-1α translation in cancer cells
Keywords: کیناز فعال p21; Pak4; HIF-1α; Hypoxia; Akt; mTOR; 4E-BP1; Pak; p21-activated kinase; HIF; hypoxia-inducible factor; PHD; prolyl hydroxylase domain-containing protein; FBS; fetal bovine serum; HRE; hypoxia response element; PGK-1; phosphoglycerate kinase-1; DFO; desferri
Regulation of merlin by protein phosphatase 1-TIMAP and EBP50 in endothelial cells
Keywords: کیناز فعال p21; BPAEC; Bovine Pulmonary Artery Endothelial Cells; ERM; ezrin, radixin, moesin; FERM; band 4.1, ezrin, radixin, moesin; GST; glutathione S-transferase; ILK; integrin-linked kinase; IP; immunoprecipitation; MYPT; myosin phosphatase target subunit; NF2; neur
Discovery of indolin-2-one derivatives as potent PAK4 inhibitors: Structure-activity relationship analysis, biological evaluation and molecular docking study
Keywords: کیناز فعال p21; p21-Activated kinase; PAK4 inhibitor; Indolin-2-one; Structure-activity relationship; Molecular docking;
Development of 2, 4-diaminoquinazoline derivatives as potent PAK4 inhibitors by the core refinement strategy
Keywords: کیناز فعال p21; p21-activated kinase; PAK4 inhibitor; Synthesis; Anti-cancer; 2,4-diaminoquinazoline; ASRZBBITPATROI-UHFFFAOYSA-N;
Structure, biochemistry, and biology of PAK kinases
Keywords: کیناز فعال p21; PAK; p21-activated kinase; AID; auto-inhibitory domain; PBD; p21-binding domain; p21-Activated kinase; PAK; Cytoskeleton remodeling; Cancer; Nervous system; Heart;
Regulation of HC11 mouse breast epithelial cell differentiation by the E-cadherin/Rac axis
Keywords: کیناز فعال p21; cRac1; Cellular Rac1; CRIB; Cdc42/Rac-interactive binding; E-cadherin; Epithelial cadherin; ECL; enhanced chemiluminescence; EGF; Epidermal growth factor; GAP; GTPase activating protein; GDP; guanosine 5â²-diphosphate; GEF; guanine nucleotide exchange fa
Redox regulation of the actin cytoskeleton and its role in the vascular system
Keywords: کیناز فعال p21; α; alpha; β; beta; γ; gamma; G-actin; globular actin; F-actin; filamentous actin; ROS; reactive oxygen species; O2â¢â; superoxide; H2O2; hydrogen peroxide; HOâ¢; hydroxyl radical; RNS; reactive nitrogen species; NO; nitric oxide; â¢NO2; nitrogen d
Pervanadate induces Mammalian Ste20 Kinase 3 (MST3) tyrosine phosphorylation but not activation
Keywords: کیناز فعال p21; Cys; cysteine; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth factor receptor; GPCR; G protein-coupled receptor; HEK 293; human embryonic kidney 293; HPK1; hematopoietic progenitor kinase 1; MST; mammalian Ste20 kinase; MAP4K; MAP kinase
An optimized synthesis of the potent and selective Pak1 inhibitor FRAX-1036
Keywords: کیناز فعال p21; p21-Activated kinase; PAK inhibitor; FRAX-1036;
Expression of p21-activated kinases 1 and 3 is altered in the brain of subjects with depression
Keywords: کیناز فعال p21; ANCOVA; analysis of covariance; PAK; p21-activated kinase; PFC; prefrontal cortex; PMI; postmortem interval; qPCR; quantitative polymerase chain reaction; RT; reverse transcription; postmortem; mRNA expression; coexpression analysis; p21-activated kinase;
P21-activated kinase 1 and 4 were associated with colorectal cancer metastasis and infiltration
Keywords: کیناز فعال p21; P21-activated kinase; Colorectal cancer; Gene expression; Recurrence; Metastasis
Sec8 regulates cytokeratin8 phosphorylation and cell migration by controlling the ERK and p38 MAPK signalling pathways
Keywords: کیناز فعال p21; IF; intermediate filament; MAPKs; mitogen-activated protein kinases; MAP2K; MAPK kinase; MAP3K; MAPK kinase kinase; ERK; extracellular signal-regulated kinase; JNK; c-jun N-terminal kinase; KSR; kinase suppressor of Ras; MEK1/2; ERK kinase 1/2; JIP4; JNK-
PAK1 is involved in sensing the orientation of collagen stiffness gradients in mouse fibroblasts
Keywords: کیناز فعال p21; ECM; extracellular matrix; PAK1; p21-activated kinase; PAK1 K299R; p21-activated kinase dominant negative-kinase dead; PAK1 KD; p21-activated kinase knockdown; PAK1 T423E; p21-activated kinase constitutively active; PAK1 OE; p21-activated kinase over-expr
CDK5 knockdown in astrocytes provide neuroprotection as a trophic source via Rac1
Keywords: کیناز فعال p21; CDK5; cyclin-dependent kinase; GLU; glutamate; AD; Alzheimer's disease; DIV; day in vitro; ROS; reactive oxygen species; BDNF; brain-derived neurotrophic factor; ROCK; Rho kinase; LDH; lactate dehydrogenase; G-LISA; GTP enzyme-linked immunosorbent assay;
Regulation of hippocampal synaptic plasticity by BDNF
Keywords: کیناز فعال p21; 4E-BPs; eIF4E-binding proteins; 5-HT; 5-hydroxytryptamine; ADF; actin-depolymerising factor; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptors; Arc; activity-regulated cytoskeleton-associated protein; BDNF; brain-derived n
BDNF mechanisms in late LTP formation: A synthesis and breakdown
Keywords: کیناز فعال p21; Brain-derived neurotrophic factor (BDNF); TrkB signaling; Synaptic plasticity; Long-term potentiation (LTP); Protein synthesis; Translation control; Cytoskeletal dynamics; Arc; activity-regulated cytoskeleton-associated protein; AS; Angelman syndrome; AS-
BDNF-induced local protein synthesis and synaptic plasticity
Keywords: کیناز فعال p21; Brain-derived neurotrophic factor (BDNF); Synaptic plasticity; Long-term potentiation (LTP); Translation; RNA transport; ADF; actin-depolymerizing factor; A2RE; heterogeneous nuclear ribonucleoprotein (hnRNP) A2 response element; Arc; activity-regulated c
p21-activated kinases and gastrointestinal cancer
Keywords: کیناز فعال p21; AID; auto-inhibitory domain; CDK5RAP3; CDK5 kinase regulatory subunit-associated protein 3; CRC; colorectal carcinoma; EGFR; epithelial growth factor receptor; GAP; GTPase-activating protein; HBV; hepatitis B virus; HBx; HBV X protein; HCC; hepatocellular
Inhibition of formyl peptide-stimulated superoxide anion generation by Fal-002-2 occurs mainly through the blockade of the p21-activated kinase and protein kinase C signaling pathways in ratneutrophils
Keywords: کیناز فعال p21; Neutrophils; Superoxide anion; p21-Activated kinase; Protein kinase C; p47phox;
PI3K regulates branch initiation and extension of cultured mammary epithelia via Akt and Rac1 respectively
Keywords: کیناز فعال p21; ECM; extracellular matrix; EGF; epidermal growth factor; FGF; fibroblast growth factor; GEF; guanine nucleotide exchange factor; HGF; hepatocyte growth factor; MMP; matrix metalloproteinase; PAK; p21-activated kinase; PI3K; phosphoinositide 3-kinase; PTEN
The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity
Keywords: کیناز فعال p21; 5-FU; 5-fluorouracil; BrdU; 5-bromo-2â²-deoxyuridine; FACS; fluorescence activated cell sorting; FAK; focal adhesion kinase; GMP; granulocyte-monocyte progenitor; HPC; hematopoietic progenitor cell; KLS; c-Kit+lineageâSca-1+; LT-HSC; long-term hemato
The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis
Keywords: کیناز فعال p21; GPCR; G protein-coupled receptor; GRK; GPCR kinase; GIT; GRK-interacting protein; ARF-GAPs; ADP-ribosylation factor GTPase-activating proteins; GEF; guanine nucleotide exchange factor; MSC; mesenchymal stem cell; qCT; quantitative micro-computed tomograph
Phosphorylation of β-catenin at serine 663 regulates its transcriptional activity
Keywords: کیناز فعال p21; p21-Activated kinase; β-Catenin; Phosphorylation; Transcription;
The signaling mechanisms mediating the inhibitory effect of TCH-1116 on formyl peptide-stimulated superoxide anion generation in neutrophils
Keywords: کیناز فعال p21; Neutrophil; Superoxide anion; p21-Activated kinase; Akt; Protein kinase C; p47phox;
Small GTPases Rap1 and RhoA regulate superoxide formation by Rac1 GTPases activation during the phagocytosis of IgG-opsonized zymosans in macrophages
Keywords: کیناز فعال p21; DHE; dihydroethidium; DMEM; Dulbecco's modified Eagle medium; Epac; exchange protein directly activated by cAMP; ERK; extracellular signal-regulated kinases; FBS; fetal bovine serum; FITC; fluorescein isothiocyanate; GAP; GTPase activating proteins; GDI;
Hepatitis B Virus X Protein Confers Resistance of Hepatoma Cells to Anoikis by Up-regulating and Activating p21-Activated Kinase 1
Keywords: کیناز فعال p21; Liver Cancer; Mouse Model; Metastasis; Apoptosis Signal Transduction; HBV; hepatitis B virus; HBx; hepatitis B virus X protein; HCC; hepatocellular carcinoma; Mcl1; myeloid cell leukemia sequence 1; PAK; p21-activated kinase; PI; propidium iodide; PVTT; p
Rho GTPases as regulators of morphological neuroplasticity
Keywords: کیناز فعال p21; C3; Clostridium botulinum ribosyltransferase; cAMP; cyclic adenosine monophosphate; Cdc42; cell division control protein 42 homolog; CRIB; Cdc42/Rac interactive binding; DRG; dorsal root ganglia; ERK; extracellular signal-regulated kinase; FAK; focal adhe
The cell adhesion-associated protein Git2 regulates morphogenetic movements during zebrafish embryonic development
Keywords: کیناز فعال p21; ArfGAP; Arf GTPase activating protein; EVL; enveloping layer; ECM; Extracellular matrix; FAK; focal adhesion kinase; PAK; p21-activated kinase; PIX; PAK interacting exchange factor; Zebrafish; Epiboly; Gastrulation; Git2; Non-muscle Myosin II; Blebbistati
Merlin-Deficient Human Tumors Show Loss of Contact Inhibition and Activation of Wnt/β-Catenin Signaling Linked to the PDGFR/Src and Rac/PAK Pathways
Keywords: کیناز فعال p21; ABC; active β-catenin, dephosphorylated on Ser37 and Thr41; AJ; adherens junction; ERM; ezrin-radixin-moesin; NF2; neurofibromatosis type 2; NHERF1/EBP50; Na+-H+ exchanger regulatory factor 1/ERM binding protein; PAK; p21-activated kinase; PDGFR; platele
POSH2 is a RING finger E3 ligase with Rac1 binding activity through a partial CRIB domain
Keywords: کیناز فعال p21; Plenty of SH3 domains; Src homology 3; p21-Activated kinase; CRIB domain; E3 ligasePOSH, plenty of SH3 domains; PAK, p21-activated kinase; CRIB, Cdc42/Rac1-interactive binding; SH3, Src homology 3
CK2β interacts with and regulates p21-activated kinases in Drosophila
Keywords: کیناز فعال p21; Drosophila; CK2; Regulatory β-subunit; p21-activated kinase;
PAK signalling in neuronal physiology
Keywords: کیناز فعال p21; p21-Activated kinase; Brain; Neuronal development; Neurodegenerative diseases; Synaptic plasticity
Inhibition of superoxide anion generation by CHS-111 via blockade of the p21-activated kinase, protein kinase B/Akt and protein kinase C signaling pathways in rat neutrophils
Keywords: کیناز فعال p21; Neutrophil; Superoxide anion; p21-Activated kinase; Akt; Protein kinase C; p47phox
Rho GTPases and p21-activated kinase in the regulation of proliferation and apoptosis by gastrins
Keywords: کیناز فعال p21; β-Catenin; Colorectal cancer; Gastrins; P21-activated kinase; Rho
A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells
Keywords: کیناز فعال p21; MEK; mitogen-activated protein/extracellular signal-regulated kinase; TPA; 12-O-tetradecanoyl phorbol 13-acetate; MMP; matrix metalloproteinase; ERK; extracellular regulated kinases; HEPT; 3,5,6,7,8,3â²,4â²-heptamethoxyflavone; MEM; Eagle's minimum es
Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes
Keywords: کیناز فعال p21; Akt/PKB; P21-activated kinase; Cardiomyocytes
c-Cbl facilitates cytoskeletal effects in v-Abl transformed fibroblast through Rac1- and Rap1-mediated signaling
Keywords: کیناز فعال p21; ANOVA; analysis of variance; CA-Rac1; GST-fused constitutively active form of Rac1; CPT; 8-CPT-2'-O-Me-cAMP; EPAC; exchange protein directly activated by cAMP; FN; fibronectin; PAK; p21-activated kinase; mAb; monoclonal antibody; PI3K; phosphatidylinosito