Keywords: Eosinophils; p47phox; AMP-activated protein kinase; Reactive-oxygen species; Phosphodiesterase4; Fat mass;
مقالات ISI (ترجمه نشده)
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Mechanisms underlying modulation of podocyte TRPC6 channels by suPAR: Role of NADPH oxidases and Src family tyrosine kinases
Keywords: Apo; apocynin; CGT; cilengitide; CKD; chronic kidney disease; FSGS; focal and segmental glomerulosclerosis; gp91phox; catalytic subunit of NADPH oxidase 2; Nox2; NADPH oxidase 2; Nox4; NADPH oxidase 4; NSC23766; N6â[2â[[4â(Diethylamino)â1âmethyl
NOX isoforms in the development of abdominal aortic aneurysm
Keywords: Abdominal aortic aneurysms (AAA); Angiotensin II (Ang II); Nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase/NOX); NOX1; NOX2; NOX4; p47phox; Endothelial nitric oxide synthase (eNOS) uncoupling; Dihydrofolate reductase (DHFR); Superoxide;
Suppressed ubiquitination of Nrf2 by p47phox contributes to Nrf2 activation
Keywords: Nrf2; p47phox; NADPH oxidase; Keap1; Ubiquitination; Lung inflammation;
Organizers and activators: Cytosolic Nox proteins impacting on vascular function
Keywords: AIR; Autoinhibitory region; cAMP; Cyclic adenosine mono-phosphate; HUVEC; Human umbilical vein endothelial cells; LPS; Lipopolysaccharide; PI3K; Phosphatidyl inosite 3-kinase; PKA; Protein kinase A; PKC; Protein kinase C; PMN; Polymorph-nuclear neutrophil
Quercetin attenuates high fat diet-induced atherosclerosis in apolipoprotein E knockout mice: A critical role of NADPH oxidase
Keywords: Quercetin; Atherosclerosis; NADPH oxidase; p47phox; Oxidative stress; Reactive oxygen species;
ROS feedback regulates the microRNA-19-targeted inhibition of the p47phox-mediated LPS-induced inflammatory response
Keywords: LPS; miR-19; p47phox; Oxidative stress; Raw264.7Â cell;
The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues
Keywords: NCF1; p47phox; NADPH oxidase; Neutrophils; Chlamydia; Hydrosalpinx;
Extra virgin olive oil rich in polyphenols modulates VEGF-induced angiogenic responses by preventing NADPH oxidase activity and expression
Keywords: Matrix metalloproteinases; Nox2; Nox4; p47phox; Oxidative stress; Endothelial cells;
A founder effect for p47phoxTrp193Ter chronic granulomatous disease in Kavkazi Jews
Keywords: Chronic granulomatous disease; NADPH oxidase; p47phox; NCF1; Kavkazi Jews; Founder effect
The role of NADPH oxidase in taurine attenuation of Streptococcus uberis-induced mastitis in rats
Keywords: Streptococcus uberis; Mastitis; Taurine; p47phox; p22phox;
Zymosan induces NADPH oxidase activation in human neutrophils by inducing the phosphorylation of p47phox and the activation of Rac2: Involvement of protein tyrosine kinases, PI3Kinase, PKC, ERK1/2 and p38MAPkinase
Keywords: Neutrophils; NADPH oxidase; p47phox; Rac2; ROS; Signaling;
Inhibition of formyl peptide-stimulated superoxide anion generation by Fal-002-2 occurs mainly through the blockade of the p21-activated kinase and protein kinase C signaling pathways in ratneutrophils
Keywords: Neutrophils; Superoxide anion; p21-Activated kinase; Protein kinase C; p47phox;
p38 Mitogen-activated protein kinase and extracellular signal-regulated kinase signaling pathways are not essential regulators of formyl peptide-stimulated p47phox activation in neutrophils
Keywords: Neutrophils; Superoxide anion; Mitogen-activated protein kinase; Extracellular signal-regulated kinase; Protein kinase C; p47phox;
Human C-reactive protein accentuates macrophage activity in biobreeding diabetic rats
Keywords: C-reactive protein; NF-κB; Macrophages; Tissue factor; PAI-1; PKC; p47Phox
Resveratrol up-regulates SIRT1 and inhibits cellular oxidative stress in the diabetic milieu: mechanistic insights
Keywords: SIRT1; FOXO3a; p47phox; Oxidative stress; Resveratrol and diabetes
Trimer hydroxylated quinone derived from apocynin targets cysteine residues of p47phox preventing the activation of human vascular NADPH oxidase
Keywords: Human vascular NADPH oxidase; Enzyme inhibition; Apocynin-derived oligophenols; p47phox; p22phox; Free radicals
The signaling mechanisms mediating the inhibitory effect of TCH-1116 on formyl peptide-stimulated superoxide anion generation in neutrophils
Keywords: Neutrophil; Superoxide anion; p21-Activated kinase; Akt; Protein kinase C; p47phox;
Increased NADPH oxidase-derived superoxide is involved in the neuronal cell death induced by hypoxia–ischemia in neonatal hippocampal slice cultures
Keywords: Hypoxia–ischemia; Neuronal cell death; Apoptosis; Superoxide; Hydrogen peroxide; NADPH oxidase; p47phox; p38MAP kinase; Neonatal brain; Free radicals
Neuroinflammatory and oxidative stress phenomena in MPS IIIA mouse model: The positive effect of long-term aspirin treatment
Keywords: MPS IIIA; Mucopolysaccharidosis (MPS) type IIIA, Sanfilippo disease type A; LSD; Lysosomal storage diseases; GAGs; Glycosaminoglycans; CNS; Central nervous system; GFAP; Glial fibrillary acidic protein; NSAIDs; Nonsteroidal anti-inflammatory drugs; PCR; P
Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: Role of PKCζ-mediated p47phox phosphorylation
Keywords: Type II AEC; Nox; p47phox; Cytokine expression; Lipopolysaccharide; PKCζ;
Src kinase participates in LPS-induced activation of NADPH oxidase
Keywords: Src kinase; PI3 kinase; Superoxide; NADPH oxidase; Macrophage; Oxidant production; p47phox; TLR4; LPS; CD14
Glycated albumin activates NADPH oxidase in rat mesangial cells through up-regulation of p47phox
Keywords: Glycated albumin; NADPH oxidase; p47phox; Mesangial cells; TGF-β; Extracellular matrix protein;
Peptide-based inhibitors of the phagocyte NADPH oxidase
Keywords: DPI, diphenylene iodonium; CGD, chronic granulomatous disease; fMLF, formyl-methionyl-leucyl-phenylalanine; MPO, myeloperoxidase; phox, phagocyte oxidase; ROS, reactive oxygen speciesPhagocytes; NADPH oxidase; Inhibitors; gp91phox/NOX2; p22phox; p47phox
Apocynin attenuate spatial learning deficits and oxidative responses to intermittent hypoxia
Keywords: Apocynin; Intermittent hypoxia; Spatial learning; NADPH oxidase; Oxidative stress; P22phox; P47phox
Homocysteine promotes proliferation and activation of microglia
Keywords: Homocysteine; Microglia; Proliferation; Activation; NAD(P)H oxidases; Reactive oxygen species; p47phox; p38 MAPK
Conformational changes in p47phox upon activation highlighted by mass spectrometry coupled to hydrogen/deuterium exchange and limited proteolysis
Keywords: NADPH oxidase; p47phox; H/D exchange; Limited proteolysis; Conformational changeACN, acetonitrile; phox, phagocyte oxidase; AIR, autoinhibitory region; SH3, src homology 3; PX, Phox homology; SAXS, small-angle X-ray scattering; GST, glutathione S-transfer
FPRL1-mediated induction of superoxide in LL-37-stimulated IMR90 human fibroblast
Keywords: Reactive oxygen species; Human fibroblasts; NADPH oxidase; FPRL1; LL-37; ERKs; p47phox
Inhibition of superoxide anion generation by CHS-111 via blockade of the p21-activated kinase, protein kinase B/Akt and protein kinase C signaling pathways in rat neutrophils
Keywords: Neutrophil; Superoxide anion; p21-Activated kinase; Akt; Protein kinase C; p47phox
Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-κB in human tracheal smooth muscle cells
Keywords: CSE; cigarette smoke extract; COPD; chronic obstructive pulmonary disease; COX; cyclooxygenase; PG; prostaglandin; AA; arachidonic acid; cPLA2; cytosolic phospholipase A2; HTSMCs; human tracheal smooth muscle cells; DMEM/F-12; Dulbecco's modified Eagle's
Protein kinase C-α and -δ are required for NADPH oxidase activation in WKYMVm-stimulated IMR90 human fibroblasts
Keywords: NADPH oxidase; Formyl-peptides receptor; WKYMVm; Protein kinase C; ERKs; p47phox
Identification of an actin-binding site in p47phox an organizer protein of NADPH oxidase
Keywords: O2-, superoxide; AIR, autoinhibitory region; SDS, sodium dodecyl sulfate; PAGE, polyacrylamide gel electrophoresis; F-actin, filamentous actin; G-actin, globular actinSuperoxide; NADPH oxidase; p47phox; β-Actin; Protein–protein interaction; Actin-binding
Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats
Keywords: p47phox; SHR (spontaneously hypertensive rat); Spontaneous tone; Superoxide
Insulin generates free radicals in human fibroblasts ex vivo by a protein kinase C-dependent mechanism, which is inhibited by pravastatin
Keywords: Hydroxymethylglutaryl-CoA reductase inhibitors; Insulin; NADPH oxidase; PKC δ; p47phox; Reactive oxygen species;
Conditional haploinsufficiency of NCF1 (encoding p47phox), a signaling gene with a heterozygous phenotype potentially subject to natural selection
Keywords: p47phox; NCF1 gene; Granulocytes;
Inhibition of human neutrophil reactive oxygen species production and p67phox translocation by cigarette smoke extract
Keywords: Neutrophils; Cigarette smoke; Reactive oxygen species; NADPH oxidase; p47phox; p67phox;
Effect of sulfur amino acids on stimulus-induced superoxide generation and translocation of p47phox and p67phox to cell membrane in human neutrophils and the scavenging of free radical
Keywords: Superoxide; Human neutrophils; Sulfur amino acids; p47phox; p67phox; Scavenging;
Immunohistochemical study of p47Phox and gp91Phox distributions in rat brain
Keywords: Other systems of the CNS; Comparative neuroanatomy; p47Phox; gp91Phox; Immunohistochemistry; Rat; NADPH oxidase; Brain;
A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox
Keywords: Phagocyte; NADPH oxidase; Superoxide; p47phox; p67phox; SH3 domain; Proline-rich region;
Molecular composition and regulation of the Nox family NAD(P)H oxidases
Keywords: ROS; Nox; Duox; gp91phox; p22phox; p47phox; p67phox; Noxo1; Noxa1; Rac;