Keywords: Comfrey; Herbal medicine; SurveyAMH, Association of Master Herbalists; CPP, College of Practitioners of Phytotherapy; NIMH, National Institute of Medical Herbalists; PAs, pyrrolizidine alkaloids
مقالات ISI (ترجمه نشده)
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Involvement of organic cation transporter 1 and CYP3A4 in retrorsine-induced toxicity
Keywords: PAs, pyrrolizidine alkaloids; RTS, retrorsine; CYP, cytochrome P450; OCT, organic cation transporter; MDCK, Madin–Darby canine kidney; PCRH, primary cultured rat hepatocytes; SLC, solute carrier; MATE, multidrug and toxin extrusion; P-gp/MDR1, P-glycoprot
Synergistic effects of pyrrolizidine alkaloids and lipopolysaccharide on preterm delivery and intrauterine fetal death in mice
Keywords: LPS, lipopolysaccharide; PAs, pyrrolizidine alkaloids; RTS, retrorsine; MCT, monocrotaline; GD, gestational day; IUGR, intrauterine growth retardation; ROS, reactive oxygen species; TBARS, thiobarbituric acid reactive substancesLipopolysaccharide; Pyrroli
Arbuscular mycorrhizal colonization, plant chemistry, and aboveground herbivory on Senecio jacobaea
Keywords: Arbuscular mycorrhizal fungi; Insect herbivores; Plant chemistry; Senecio jacobaea; Plant diversityAMF, arbuscular mycorrhizal fungi; C, carbon; N, nitrogen; P, phosphorous; PAs, pyrrolizidine alkaloids
Proteomic characterization of the possible molecular targets of pyrrolizidine alkaloid isoline-induced hepatotoxicity
Keywords: PAs, pyrrolizidine alkaloids; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HPAs, hepatotoxic pyrrolizidine alkaloids; 2D-PAGE, two-dimensional polyacrylamide gel electrophoresis; Acr, acrylamide; Bis, bisacrylamide; CHAPS, 3-[(3-cholami
Intracellular glutathione plays important roles in pyrrolizidine alkaloids-induced growth inhibition on hepatocytes
Keywords: GSH, reduced glutathione; GSSG, oxidized glutathione; PAs, pyrrolizidine alkaloids; MTT, 3-(4,5-dimethylthiazol-2-yl) 2,5-diphenyltetrazolium bromide; ROS, reactive oxygen species; DTNB, 5,5′-dithio-bis (2-nitrobenzoic acid); TNB, 5-thio-2-nitrobenzoic ac
Protection of S-adenosyl methionine against the toxicity of clivorine on hepatocytes
Keywords: GSH, reduced glutathione, γ-l-glutamyl-l-cysteinyl-glycine; PAs, pyrrolizidine alkaloids; SAM, S-adenosyl-l-methionine; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; ROS, reactive oxygen species; DTNB, 5,5′-dithio-bis (2-nitrobenzoic
Involvement of Bcl-xL degradation and mitochondrial-mediated apoptotic pathway in pyrrolizidine alkaloids-induced apoptosis in hepatocytes
Keywords: NTP, National Toxicology Program; PARP, Poly(ADP-ribose) polymerase; MHRA, British Medicines Healthcare Products Regulatory Agency; PAs, Pyrrolizidine alkaloids; PBS, phosphate-buffered saline; RPMI1640, Roswell Park Memorial Institute 1640; FBS, fetal bo