A sensitive cell-based method to screen for selective inhibitors of SMS1 or SMS2 using HPLC and a fluorescent substrate
Keywords: SM, sphingomyelin; Cer, ceramide; GlcCer, glucosylceramide; PC, phosphatidylcholine; SMS, sphingomyelin synthase; GlcT, UDP-glucose:ceramide β-1,1′-glucosyltransferase; (GlcCer, synthase); PC-PLC, phosphatidylcholine-specific phospholipase C; HPLC, high-p