Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates
Keywords: 3â²-CMP; cytidine 3â²-monophosphate; Câ¯>â¯p; Cytidine 2â²,3â²-cyclic phosphate; ECP; Eosinophil Cationic Protein; poly(C); Polycytidylic acid; RMSD; Root mean square deviation; Endoribonuclease; RNaseA; RNase6; Substrate binding site; Protein cryst