Keywords: WAT; White adipose tissue; BAT; Brown adipose tissue; UCP-1; Uncoupling protein 1; sWAT; Subcutaneous white adipose tissue; PDE5i; Phosphodiesterase type-5 inhibitor; cGMP; cyclic guanosine monophosphate; TC; Total cholesterol; LDL-C; Low-density lipoprot
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Keywords: POMC; pro-opiomelanocortin; NPY; neuropeptide Y; AgRP; agouti-related peptide; PCOS; polycystic ovary syndrome; BAT; brown adipose tissue; WAT; white adipose tissue; Myf5; myogenic factor 5; PRDM16; PRD1-BF1-RIZ1 homologous domain containing 16; UCP1; the
Keywords: Dihydrocapsiate; HFD; Obesity; Glucose intolerance; Hepatic steatosis; ACOX1; Acyl-CoA oxidase 1; ADIPO; adiponectin; AIN; American Institute of Nutrition; ANOVA; 1-way analysis of variance; BAT; brown adipose tissue; BMI; body mass index; C/EBPβ; CCAAT/
Keywords: α-MSH; α-melanocyte-stimulating hormone; BAIBA; β-aminoisobutyric acid; ATGL; adipose triglyceride lipase; AR-beta3; adrenergic receptor beta 3; BMP; bone morphogenetic protein; BAT; brown adipose tissue; CPT1; carnitine palmitoyltransferase 1; CD36; c
Keywords: 4E-BP; eukaryotic initiation factor 4E-binding protein;; ATscKO; Tsc1Lox/Lox adiponectin-cre+/â mice; ATscWT; Tsc1Lox/Lox adiponectin-creâ/â mice; C/EBP; CCAAT/enhancer-binding protein; CYC1; cytochrome c-1; DEPTOR; DEP domain-containing mTOR-intera
Keywords: AT; adipose tissue; ATGL; adipose triglyceride lipase; AMPK; AMP activated kinase; BAT; brown adipose issue; CGI58; comparative gene identification 58; CIDEA; Cell death induced DNA fragmentation-factor-α-like effector A; CT; computed tomography; G0S2; G
Keywords: Bmp4; bone morphogenetic protein 4; EGCG; (-)-epigallocatechin-3-gallate; Ex; voluntary exercise; GTE; decaffeinated green tea extract; HF; high fat diet; Lipe; hormone sensitive lipase; LF; low fat; mt-Co3; cytochrome C oxidase subunit III; mt-Cytb; cyto
Keywords: Selenium; Selenate; High fat diet; Obesity; Insulin resistance; BAT; brown adipose tissue; C/EBP; CCAAT/enhancer binding protein; DGAT2; diacylglycerol acyltransferase 2; FAS; fatty acid synthase; H&E; haematoxylin and eosin; HF; high fat; HOMA-IR; homeos
Keywords: adipose-derived stem cells; ASCs; atomic force microscopy; AFM; basic fibroblast growth factors; bFGFs; body mass index; BMI; bone morphogenetic protein; BMP; brown adipose tissue; BAT; CCAAT/enhancer-binding protein; C/EBP; cyclic adenosine monophosphate
Keywords: Transdifferentiation; Brown adipocyte; Paucilocular adipocyte; Thermogenesis; PRDM16; PGC1α
Keywords: WAT; white adipose tissue; BAT; brown adipose tissue; MSC; mesenchymal stem cell; UCP1; uncoupling protein 1; PRDM16; PR domain containing 16; PPARγ; peroxisome proliferator-activated receptor gamma; BMP; bone morphogenic protein; PGC1; peroxisome prolif
Liver kinase B1 induces browning phenotype in 3â¯T3-L1 adipocytes
Keywords: LKB1; Liver kinase B1; WAT; white adipose tissue; BAT; brown adipose tissue; UCP1; uncoupling protein 1; AMPK; adenosine monophosphate-activated protein kinase; PPARγ; Peroxisome proliferator-activated receptor γ; PGC-1α; PPARγ coactivator-1α; PRDM16
Maternal n-3 PUFA supplementation promotes fetal brown adipose tissue development through epigenetic modifications in C57BL/6 mice
Keywords: ARA; (arachidonic acid); Cidea; (cell death-inducing DNA fragmentation factor α-like effector A); DHA; (docosahexaenoic acids); EHMT1; (euchromatic histone N-lysine methyltransferase 1); EPA; (eicosapentaenoic acids); eWAT; (epididymal white adipose tiss
RBM4a modulates the impact of PRDM16 on development of brown adipocytes through an alternative splicing mechanism
Keywords: Alternative splicing; Brown adipocyte; PRDM16; RBM4a;
Adiponectin AS lncRNA inhibits adipogenesis by transferring from nucleus to cytoplasm and attenuating Adiponectin mRNA translation
Keywords: AdipoQ; Adiponectin; AS lncRNA; antisense long noncoding RNA; FISH; fluorescence in situ hybridization; RPA; ribonuclease protection assay; iWAT; inguinal white adipose tissue; eWAT; epididymal white adipose tissue; BAT; brown adipose tissue; TG; triglyce
Raspberry promotes brown and beige adipocyte development in mice fed high-fat diet through activation of AMP-activated protein kinase (AMPK) α1
Keywords: AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; CD137; cluster of differentiation 137; Cidea; cell death-inducing DFFA-like effector A; Cox7al; cytochrome c oxidase subunit Vlla polypeptide 1; Cyto C; cytochrome c; Elovl3; elongation of ver
A novel brown adipocyte-enriched long non-coding RNA that is required for brown adipocyte differentiation and sufficient to drive thermogenic gene program in white adipocytes
Keywords: BAT; brown adipose tissue; WAT; white adipose tissue; ETC; electron transport chain; Ucp1; uncoupling protein 1; Cebpα/β/δ; CCAAT/enhancer-binding proteins α/β/δ; Pparγ; peroxisome proliferator-activated receptor gamma; Pgc1α; Pparγ coactivator 1
Grape pomace extract induced beige cells in white adipose tissue from rats and in 3T3-L1 adipocytes
Keywords: AMPK; AMP kinases; ATGL; adipose triglyceride lipase; BAT; brown adipose tissue; Ctrl; control; EC; (â)-epicatechin; ERK; extracellular signal-regulated kinase; eWAT; epididymal white adipose tissue; FFA; free fatty acids; GPE; grape pomace extract; HFD
Palmitoyl lactic acid induces adipogenesis and a brown fat-like phenotype in 3T3-L1 preadipocytes
Keywords: Krill oil; Beige; Adipogenesis; PPARγ agonist; PRDM16; Palmitoyl lactic acid;
Hypoxia-induced miR-214 expression promotes tumour cell proliferation and migration by enhancing the Warburg effect in gastric carcinoma cells
Keywords: miR-214; PRDM16; A2AR; Hypoxia; Warburg effect; Gastric carcinoma;
STAT3: The art of multi-tasking of metabolic and immune functions in obesity
Keywords: Signal transducer and activator of transcription 3; Obesity; Metabolism; Lipid; Immune; AgRP; Agouti-related peptide; AMPK; AMP-activated protein kinase; AOX; acyl-CoA oxidase; ARC; arcuate nucleus; ATGL; adipose triglyceride lipase; BAT; brown adipose ti
Long non-coding RNAs regulation in adipogenesis and lipid metabolism: Emerging insights in obesity
Keywords: lncRNAs; Obesity; White adipogenesis; Brown adipocyte differentiation; Lipid metabolism; Therapeutics; WAT; white adipose tissue; BAT; brown adipose tissue; Pparg; peroxisome proliferator-activated receptor γ; Cebpa; CCAAT/enhancer binding protein α; Fa
Adipocytes spectrum - From homeostasia to obesity and its associated pathology
Keywords: Acrp30 (AdipoQ); adiponectin gene; AdipoR; adiponectin receptor; AGE; angiotensinogen; ALP; alkaline phosphatase; Ang II; angiotensin II; Angptl2; angiopoietin-like protein-2; Aqp7; aquaporin-7; aP2; adipocyte-specific fatty acid binding protein 2 gene; A
Conserved function of the long noncoding RNA Blnc1 in brown adipocyte differentiation
Keywords: Brown adipocyte differentiation; Brown fat; Thermogenesis; Blnc1; lncRNA; EBF2; BAT; brown adipose tissue; RACE; rapid amplification of cDNA ends; Ucp1; uncoupling protein 1; Elovl3; elongation of very long chain fatty acids like 3; Cox7a1; cytochrome c o
Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo
Keywords: ABA; abscisic acid; ATMSC; adipose tissue mesenchymal stem cells; BAT; brown adipose tissue; CIDE-A; cell death-inducing DNA fragmentation factor; FAS; fatty acid synthase; GAPDH; glyceraldeyde-3-phosphate dehydrogenase; LPL; lipoprotein lipase; PCG-1α;
Browning deficiency and low mobilization of fatty acids in gonadal white adipose tissue leads to decreased cold-tolerance of transglutaminase 2 knock-out mice
Keywords: ADIPOQ; Adiponectin; AT; adipose tissue; BAT; brown adipose tissue; WAT; white adipose tissue; SCAT; subcutaneous white adipose tissue; FFA; free fatty acid; GONAT; gonadal white adipose tissue; CIDEA; cell death-inducing DFFA-like effector a; DIO2; type
The Multifaceted Roles of PRDM16: Adipose Biology and Beyond
Keywords: PRDM16; adipose; brown fat; beige fat; PRDM; transcriptional regulation
Maternal low-protein diet causes body weight loss in male, neonate Sprague–Dawley rats involving UCP-1-mediated thermogenesis
Keywords: Maternal low protein diet; Brown fat thermogenesis; Irisin; PRDM16; UCP-1; Placental irisin; FNDC5
Osteopontin-induced brown adipogenesis from white preadipocytes through a PI3K-AKT dependent signaling
Keywords: Osteopontin; Differentiation; Obesity; Adipocyte; PRDM16; AS; atherosclerosis; BA; brown adipocyte; iOPN; intracellular OPN; OPN; osteopontin; PI3K; phosphatidylinositol 3-kinase; PRDM16; PRD1-BF1-RIZ1 homologous domain containing 16; UCP-1+; uncoupling p
Role of PRDM16 and its PR domain in the epigenetic regulation of myogenic and adipogenic genes during transdifferentiation of C2C12 cells
Keywords: C/EBP; CCAAT/enhancer binding protein; ChIP; chromatin immunoprecipitation; H3K4me3; histone H3 lysine 4 trimethylation; H3K9me1; H3K9 monomethylation; mCK; muscle creatine kinase; MEF; Myocyte-specific enhancer factor; MyHC; myosin heavy chain; NFAT; nuc
α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects
Keywords: α-Lip; α-Lipoic acid; LDH; lactate dehydrogenase; mtDNA; mitochondrial DNA; Sirt1; Sirtuin 1; PGC-1α; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; Nrf1; nuclear respiratory factor 1; Tfam; mitochondrial transcription factor; C
PRDM16 sustains white fat gene expression profile in human adipocytes in direct relation with insulin action
Keywords: PRDM16; Adipogenesis; Human adipose tissue; Obesity; Insulin sensitivity
Redox-regulated fate of neural stem progenitor cells
Keywords: ARE; antioxidant response element; bHLH; basic helix-loop-helix; BMI1; B lymphoma Mo-MLV insertion region 1 homolog; CtBPs; C-terminal binding proteins; DLL4; delta-like protein 4; DVL; disheveled; DOUX; dual oxidases; ES; embryonic stem cells; EGFR; epid
1-Benzyl-4-phenyl-1H-1,2,3-triazoles improve the transcriptional functions of estrogen-related receptor γ and promote the browning of white adipose
Keywords: ERR; estrogen-related receptor; WAT; white adipose tissue; BAT; brown adipose tissue; PET; positron-emission-tomography; FGF21; fibroblast growth factor 21; MOA; mechanisms of action; UCP1; uncoupling protein 1; SHP; small heterodimer partner; ATP5b; ATP
MicroRNAs are key regulators of brown adipogenesis
Keywords: BAT; brown adipose tissue; WAT; white adipose tissue; iBAT; intrascapular brown adipose tissue; SAT; subcutaneous fat; Mef-2; myocyte enhancer factor-2; PGC-1α; Ppar-Ï co-activator; Prdm16; PR domain containing 16; C/ebpβ; CCAAT/enhancer-binding protei
Thermogenic adipocytes: From cells to physiology and medicine
Keywords: ATP; adenosine triphosphate; BAT; brown adipose tissue; BMI; body mass index; Bmp; bone morphogenetic protein; cPGI2; carbaprostacyclin; cAMP; cyclic adenosine monophosphate; C/EBPβ; CCAAT/enhancer binding protein β; cGMP; cyclic guanosine monophosphate
Manipulating molecular switches in brown adipocytes and their precursors: A therapeutic potential
Keywords: Brown adipose; Adipocyte; PRDM16; Obesity; UCP1
Early induction of a brown-like phenotype by rosiglitazone in the epicardial adipose tissue of fatty Zucker rats
Keywords: Rosiglitazone; Epicardial adipose tissue; Fatty rat; TZD; thiazolidinedione; RSG; rosiglitazone; TG; triglycerides; PPARγ; peroxisome proliferator-activated receptor gamma; RXR; retinoid X receptor; CEBP; CCAAT enhancer binding protein; RAT; retroperiton
PRDM16 expression in the developing mouse embryo
Keywords: Embryo; Development; MEL1; PRDM16; Transcription factor;
PPARα does not suppress muscle-associated gene expression in brown adipocytes but does influence expression of factors that fingerprint the brown adipocyte
Keywords: PPARα; Brown adipose tissue; Myogenin; MyoD; miR-206; Zic1; Prdm16
Ras signalling regulates differentiation and UCP1 expression in models of brown adipogenesis
Keywords: AEBP1; AE-binding protein 1; C/EBP; CCAAT/enhancer-binding protein; CS; citrate synthase; DMEM; Dulbecco's Modified Eagle's Medium; DMSO; dimethyl sulfoxide; ERK; extracellular signal-regulated kinase; FABP4; fatty acid-binding protein 4; FBS; foetal bovi
PRDM16/MEL1: A novel Smad binding protein expressed in murine embryonic orofacial tissue
Keywords: PRDM16; PR-domain containing protein-16; MEL1; MDS1/Evi1-like protein; TGFβ; transforming growth factor β; GST; glutathione S-transferase; CBP; CREB binding protein; DIG; digoxigenin; kDa; kiloDalton; kb; kilobase; E; embryonic day; GCNF; germ cell nucl