دانلود مقالات ISI درباره PTP ها + ترجمه فارسی

طیف جهش ژنهای کاندیدای هیپر فینیل آلانینمی و همبستگی ژنوتیپ-فنوتیپ در جمعیت چینی

Mutation spectrum of hyperphenylalaninemia candidate genes and the genotype-phenotype correlation in the Chinese population

Keywords: PTP ها; HPA; hyperphenylalaninemia; PAH; phenylalanine hydroxylase; BH4; tetrahydrobiopterin; NGS; next generation sequencing; MLPA; multiplex ligation-dependent probe amplification; qRT-PCR; quantitative real-time PCR; APV; allelic phenotype values; GPV; genotyp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

بینش مربوط به گلیکسیون با کارسینوم سلول

An insight on the association of glycation with hepatocellular carcinoma

Keywords: PTP ها; AGEs; advanced glycation end products; CEL; Nε-(carboxyethyl) lysine; CMA; Nω-(carboxymethyl) arginine; CML; Nε-(carboxymethyl) lysine; H2O2; hydrogen peroxide; HCC; hepato-cellular carcinoma-; HMGB1; high mobility group box-1; NAFLD; nonalcoholic fatt

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

پراکسی ایردوکسین 2 باعث کاهش حساسیت به انسولین عضلات اسکلتی شده از طریق تنظیم اکسیداسیون پروتئین تیروزین فسفاتاز

Peroxiredoxin 2 mediates insulin sensitivity of skeletal muscles through regulation of protein tyrosine phosphatase oxidation

Keywords: PTP ها; ROS; reactive oxygen species; Prx; peroxiredoxin; PTP1B; protein tyrosine phosphatase 1B; PTEN; phosphatase and tensin homologue; MEFs; mouse embryonic fibroblasts; Nac; N-acetyl cysteine; GTT; glucose tolerance test; GLUT4; glucose transporter type 4; PT

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

اهداف مولکولی اثر واربورگ و سیتوکین های التهابی در پاتوژنز پرفشاری خون عروق ریوی

Molecular targets of the Warburg effect and inflammatory cytokines in the pathogenesis of pulmonary artery hypertension

Keywords: PTP ها; DCA; dichloroacetate; FAO; fatty acid oxidation; GO; glucose oxidation; HIF-1; hypoxia-inducible factor 1; CaL channels; L-type calcium channels; NFATs; nuclear factor of activated T cells; NO; nitric oxide; MCT-PAH; monocrotaline-induced PAH; PAH; pulmon

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

ایمنی زیستی محصول پروتئین نوترکیب با طول عمر بالا

Immunogenicity of long-lasting recombinant factor VIII products

Keywords: PTP ها; APC; antigen-presenting cells; BcR; B cell receptor; EMA; European Medicines Agency; Fc; crystallizable fragment; FcγR; receptor for IgG Fc portion; FcRn; neonatal Fc receptor; FVIIa; activated factor VII; FVIII; factor VIII; GLP-1; glucagon-like peptide

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

کشف سیگنالینگ فسفوریلاسیون پویا با استفاده از طیف سنجی جرمی

Uncovering dynamic phosphorylation signaling using mass spectrometry

Keywords: PTP ها; AEX; anion exchange chromatography; CID; collision induced dissociation; DHB; 2,5-dihydroxybenzoic acid; ECD; electron capture dissociation; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EGFRvIII; epidermal growth factor receptor v

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanism of insulin-like effect of chromium(III) ions on glucose uptake in C2C12 mouse myotubes involves ROS formation

Keywords: PTP ها; DCFH DA; dichorodihydrofluorescein diacetate; DCFH 2′,7′; dichorodihydrofluorescein; DCF 2′,7′; dichorofluorescein; DMEM; dulbecco modified eagle's medium; DOG; deoxyglucose; DPI; diphenyleneiodonium; GTF; glucose tolerance factor; GLUT4; glucos

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Negative effects of artemisinin on phosphorus solubilizing bacteria in vitro

Keywords: PTP ها; PSB; phosphorus solubilizing bacteria; PTPS; the percentage of tricalcium phosphate solubilization; Artemisinin; Phosphorus solubilizing bacteria; Artemisia annua L;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Chronic exposure of the RAW246.7 macrophage cell line to H2O2 leads to increased catalase expression

Keywords: PTP ها; ROS; reactive oxygen species; GSH; glutathione; SOD; superoxide dismutase; PTPs; protein tyrosine phosphatases; NEM; N-ethylmaleimide; DTNB; 5,5-dithio-bis-(2-nitrobenzoic acid); PMA; phorbol 12-myristate 13-acetate; ASK1; apoptosis signal-regulating kina

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Flaviviridae virus nonstructural proteins 5 and 5A mediate viral immune evasion and are promising targets in drug development

Keywords: PTP ها; AAF; IFN-α-activated factor; ATA; Aurintricarboxylic acid; BDV; border disease virus; BPgV; GBV-D; BVDV-1; bovine viral diarrhea virus-1; C; capsid protein; CLRs; C-type lectin receptors; Core; core protein; CSFV; classical swine fever virus; DENV; dengu

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2018 سفارش ترجمه

OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity

Keywords: PTP ها; crystallography; Orf virus; tyrosine phosphatase; phosphatidylinositol; ORFV; Orf virus; DUSP; dual-specificity phosphatase; PTPs; protein tyrosine phosphatases; P-loop; phosphate-binding loop; PtdIns; phosphoinositides; SEC; size exclusion chromatography

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of sennoside A as a novel inhibitor of the slingshot (SSH) family proteins related to cancer metastasis

Keywords: PTP ها; PTPs; protein tyrosine phosphatases; PTKs; protein tyrosine kinases; DUSP; dual specificity phosphatase; ADF; actin-depolymerizing factor; IPTG; isopropyl-β-d-thiogalactoside; DiFMUP; 6,8-difluoro-4-methylumbelliferyl phosphate; MBP; maltose binding prot

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Redox regulation of the actin cytoskeleton and its role in the vascular system

Keywords: PTP ها; α; alpha; β; beta; γ; gamma; G-actin; globular actin; F-actin; filamentous actin; ROS; reactive oxygen species; O2•−; superoxide; H2O2; hydrogen peroxide; HO•; hydroxyl radical; RNS; reactive nitrogen species; NO; nitric oxide; •NO2; nitrogen d

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2017 سفارش ترجمه

The International Working Group on Neurotransmitter related Disorders (iNTD): A worldwide research project focused on primary and secondary neurotransmitter disorders

Keywords: PTP ها; AADC; aromatic l-amino acid decarboxylase; AR/ADGTPCH; autosomal recessive/dominant GTP-cyclohydrolase deficiency; BH4; tetrahydrobiopterin; DAT; dopamine transporter; DßH; dopamine β-hydroxylase; DHFR; dihydrofolate reductase deficiency; DHPR; dihydrop

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Nonacog beta pegol (N9-GP) in haemophilia B: A multinational phase III safety and efficacy extension trial (paradigm™4)

Keywords: PTP ها; ABR; annualised bleeding rate; AEs; adverse events; CHO; Chinese hamster ovary; CI; confidence interval; EDs; exposure days; ELISA; enzyme-linked immunosorbent assay; FIX; factor IX; IQR; interquartile range; PEG; polyethylene glycol; PTPs; previously tre

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

PTP1B confers liver fibrosis by regulating the activation of hepatic stellate cells

Keywords: PTP ها; HSCs; Hepatic stellate cells; PTP1B; Protein tyrosine phosphatase 1B; TGF-β1; Transforming growth factor-β1; MDI; Adipogenic differentiation mixture; ECM; Extracellular matrix; qHSCs; Quiescent HSCs; α-SMA; α-smooth muscle actin; col1α1; Type I colla

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction

Keywords: PTP ها; AMPK; AMP-activated protein kinase; ATM; adipose tissue macrophages; CCL; chemokine (C-C motif) ligand; CCR2; chemokine (C-C motif) receptor 2; CX3CL1; chemokine (C-X3-C motif) ligand 1; CX3CR1; chemokine (C-X3-C motif) receptor; CXCL; CXC chemokine ligan

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2016 سفارش ترجمه

Research ReportSepsis-induced brain mitochondrial dysfunction is associated with altered mitochondrial Src and PTP1B levels

Keywords: PTP ها; LPS; lipopolysaccharide; MMP; mitochondrial membrane potential; NO; nitric oxide; OXPHOS; oxidative phosphorylation; PTPs; protein tyrosine phosphatases; ROS; reactive oxygen species; SFKs; Src family kinases; SIBD; sepsis-induced brain dysfunction; Sepsi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Developmental expression and function analysis of protein tyrosine phosphatase receptor type D in oligodendrocyte myelination

Keywords: PTP ها; ISH; in situ hybridization; OPCs; oligodendrocyte progenitor cells; PFA; paraformaldehyde; PTKs; protein tyrosine kinases; PTPRD; protein tyrosine phosphatase, receptor type D; PTPRS; protein tyrosine phosphatase, receptor type S; PTPs; protein tyrosine p

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Protein tyrosine phosphatase 1B (PTP1B): A key regulator and therapeutic target in liver diseases

Keywords: PTP ها; PTKs; protein tyrosine kinases; PTPs; protein tyrosine phosphatases; PTP1B; protein tyrosine phosphatase 1B; NAFLD; non-alcoholic fatty liver disease; HCC; hepatocellular carcinoma; DSPs; dual specificity phosphatases; LMW; low molecular weight; RPTPs; tr

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleNintedanib (BIBF-1120) inhibits hepatocellular carcinoma growth independent of angiokinase activity

Keywords: PTP ها; HCC; hepatocellular carcinoma; Ab; antibody; IP; immunoprecipitation; p-STAT3; phosphorylated STAT3; PTPs; protein tyrosine phosphatases; SH2; Src homology region 2; SHP-1; SH2 domain-containing phosphatase 1; STAT3; signal transducer and activator of tra

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Inborn Error of Metabolism (IEM) screening in Singapore by electrospray ionization-tandem mass spectrometry (ESI/MS/MS): An 8 year journey from pilot to current program

Keywords: PTP ها; DBS; dried blood spot; ESI/MS/MS; electrospray ionization-tandem mass spectrometry; LC/MS/MS; liquid chromatography-tandem mass spectrometry; FAOD; fatty acid oxidation disorder; FPR; false positive rate; IEM; Inborn Errors of Metabolism; NBS; newborn scr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Role of AMPK-mediated adaptive responses in human cells with mitochondrial dysfunction to oxidative stress

Keywords: PTP ها; AMPK; AMP-activated protein kinase; CaMKs; calmodulin-dependent protein kinases; CPEO; chronic progressive external ophthalmoplegia; CREB; cAMP-responsive element-binding protein; FOXO; forkhead box O transcription factor; G6PD; glucose 6-phosphate dehydr

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Low electric fields induce ligand-independent activation of EGF receptor and ERK via electrochemical elevation of H+ and ROS concentrations

Keywords: PTP ها; EF(s); Electric field(s); LEF; Low electric fields; ROS; Reactive oxygen species; H2DCF-DA; Dichlorodihydrofluorescein diacetate; DHA; Dehydroascorbic acid; RTK; Receptor tyrosine kinase; PTPs; Protein tyrosine phosphatases; DC; Direct current; FITC; Fluo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis and evaluation of copper complexes of Schiff-base condensates from 5-substituted-2-hydroxybenzaldehyde and 2-substituted-benzenamine as selective inhibitors of protein tyrosine phosphatases

Keywords: PTP ها; Copper complexes; Protein tyrosine phosphatases; Selective inhibitor; Schiff base; CSD; Cambridge Structural Database; ESI-MS; electrospray ionization mass spectra; Hcpmp; 4-chloro-2-((phenylimino)methyl)phenol; Hnpmp; 4-bromo-2-((phenylimino)methyl)pheno

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2013 سفارش ترجمه

Amino acid disorders detected by quantitative amino acid HPLC analysis in Thailand: An eight-year experience

Keywords: PTP ها; ASL; argininosuccinate lyase; ASS; argininosuccinate synthetase; CPS1; carbamoylphosphate synthetase I; HCY; homocystinuria; HPA; hyperphenylalaninemia; HPLC; high-performance liquid chromatography; IEM; inborn error of metabolism; MSUD; maple syrup urine

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Genome-wide biochemical analysis of Arabidopsis protein phosphatase using a wheat cell-free system

Keywords: PTP ها; PPase; protein phosphatase; Tyr; tyrosine; Ser; serine; Thr; threonine; PPPs; serine/threonine-specific protein phosphatases; PPMs; metal ion-dependent phosphoprotein phosphatases; PTPs; tyrosine-specific phosphatases; DSPs; dual-specificity phosphatases;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Photothermal microfluidic sensor based on an integrated Young interferometer made by ion exchange in glass

Keywords: PTP ها; Borosilicate; Chemical analysis; Chemical sensor; Ion exchange; Lab-on-a-chip; Microfluidics; Online monitoring; Optofluidics; Photothermal; PTPS; Thermal-lens spectrometry; Young interferometer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Dinuclear copper complexes of organic claw: Potent inhibition of protein tyrosine phosphatases

Keywords: PTP ها; Dinuclear copper complexes; PTPs; Inhibitor; Selectivity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Expanding the role of Src and protein-tyrosine phosphatases balance in modulating osteoblast metabolism: Lessons from mice

Keywords: PTP ها; Osteoblast; Osteoporosis; PTPs; Src; Inhibitors

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Prolonged tyrosine kinase activation of insulin receptor by pY27-caveolin-2

Keywords: PTP ها; pY27-caveolin-2; Insulin receptor; PTPs; SOCS-3; IRS-1; Rapamycin; pS727-STAT3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Effects of tyrosine kinase and phosphatase inhibitors on microtubules in Arabidopsis root cells

Keywords: PTP ها; Arabidopsis thaliana; Plant microtubules; Tyrosine phosphorylation; Inhibitors; MTs; microtubules; HA; Herbimycin A; SO; sodium orthovanadate; PTKs; protein tyrosine kinases; PTPs; protein tyrosine phosphatases;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Strategies for developing protein tyrosine phosphatase inhibitors

Keywords: PTP ها; Protein tyrosine phosphatases; PTPs; Small molecule PTP inhibitors; Inhibitor development; HTS; Virtual screening; Docking; Homology modeling; SAR; Lead optimization

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

The role of volume-sensitive ion transport systems in regulation of epithelial transport

Keywords: PTP ها; NKCC; Na+, K+, 2Cl−; RVI; volume regulatory increase; EATC; Ehrlich ascites tumour cells; SK; K channels having small conductance; IK; intermediate conductance; BK; large conductance; 2P-4TM; four transmembrane-spanning segments; TASK-2; acid sensitive

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

Protein tyrosine phosphatases regulate arachidonic acid release, StAR induction and steroidogenesis acting on a hormone-dependent arachidonic acid-preferring acyl-CoA synthetase

Keywords: PTP ها; ACS4; Arachidonic acid; PTPs; Steroidogenesis; PKA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Are other protein tyrosine phosphatases than PTPN22 associated with autoimmunity?

Keywords: PTP ها; PTPN22; PTPN12; PTPN18; PTPs; Phosphatases; Autoimmunity

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: From diabetes, obesity to cell cycle, and cancer

Keywords: PTP ها; EGFR; epidermal growth factor receptor; GHR; growth hormone receptor; IGF-IR; insulin-like growth factor I receptor; IR; insulin receptor; IRS; insulin receptor substrate; JAK; janus kinase; KO; knockout; LeptinR; leptin receptor; PDGFR; platelet derived

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Neopterin in HIV-1 infection

Keywords: PTP ها; AIDS; acquired immunodeficiency syndrome; ART; anti-retroviral therapy; CSF; cerebrospinal fluid; GTP; guanosine 5′-triphosphate; ICAM-1; intracellular adhesion molecule-1; IDO; indoleamine 2,3-dioxygenase; IFN-γ; interferon-γ; IL; interleukin; iNOS;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه