Keywords: پیرووات دهیدروژناز; Autoimmunity; Scleroderma; Autoimmune cholangitis; Pyruvate dehydrogenase; Immunoprecipitation;
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Keywords: پیرووات دهیدروژناز; G6PD; glucose 6-phosphate dehydrogenase; CNS; central nervous system; CO; carbon monoxide; CORM-A1; Carbon monoxide-releasing molecule A1; COX; cytochrome c oxidase; DMEM/F12; Dulbecco's minimum essential medium with nutrient mixture F12; FBS; foetal bovi
Keywords: پیرووات دهیدروژناز; AMPK; AMP-activated protein kinase; DCA; Dichloroacetate; FACD; Fatty acyl CoA dehydrogenase; G-6-Pase; Glucose-6-phosphatase; HFD; High-fat diet; HGP; Hepatic glucose production; KCT; β-ketoacyl CoA thiolase; LDH; Lactate dehydrogenase; MPC; Mitochondri
Keywords: پیرووات دهیدروژناز; AUD; alcohol-use disorder; ICU; intensive care unit; PDH; pyruvate dehydrogenase; BIDMC; Beth Israel Deaconess Medical Center; Alcohol use disorder; EtOH; Sepsis; Septic shock; Thiamine; Vitamin B1;
Keywords: پیرووات دهیدروژناز; ACSVL3; acyl-coA synthetase VL3; ALDH1; aldehyde dehydrogenase; ALDOA; aldolase A; ALDOC; aldolase C; AMPK; 5â² AMP-activated protein kinase; ASNS; asparagine synthetase; BTICs; brain tumor initiating cells; 3-BrOP; 3-bromo-2-oxopropionate-1-propyl ester
Keywords: پیرووات دهیدروژناز; ACC; acetyl-CoA carboxylase; ALDOA; aldolase A; AIs; aromatase inhibitors; AMPK; AMP-activated protein kinase; BC; breast cancer; CML; chronic myelogenous leukemia; CT; computed tomography; CPT1; carnitine palmitoyltransferase 1; CRC; colorectal cancer; 2
Keywords: پیرووات دهیدروژناز; 27-HC; 27-Hydroxycholesterol; 3PO; 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one; ABCG1; ATP-binding cassette subfamily G1; ACBA1; ATP-binding cassette subfamily A1; ACC1; Acetyl-Co-A carboxylase-1; AKAP4; A-kinase anchoring protein 4; ALDO; Aldolase; AM
Keywords: پیرووات دهیدروژناز; aKG; α-ketoglutarate; AA; amino acid; BM; biomass; CCM; central carbon metabolism; CDW; cell dry weight; DNT; Developmental neurotoxicity; ECAR; extracellular acidification rate; ESI; Electrospray ionization; FCCP; Carbonyl cyanide-4-(trifluoromethoxy)ph
Keywords: پیرووات دهیدروژناز; CRAT; carnitine acetyltransferase; LC-MS; Liquid Chromatography Mass Spectrometry; PDH; Pyruvate Dehydrogenase; T2DM; type 2 diabetes mellitus; ZDF; Zucker diabetic fatty; Carnitine acetyltransferase; Type 2 diabetes mellitus; Insulin; Resistance; Acylcar
Keywords: پیرووات دهیدروژناز; DCA; dichloroacetate; FAO; fatty acid oxidation; GO; glucose oxidation; HIF-1; hypoxia-inducible factor 1; CaL channels; L-type calcium channels; NFATs; nuclear factor of activated T cells; NO; nitric oxide; MCT-PAH; monocrotaline-induced PAH; PAH; pulmon
Keywords: پیرووات دهیدروژناز; mtFASII; mitochondrial fatty acid synthesis type II; ACPM; mitochondrial acyl carrier protein; PP; phosphopantetheine cofactor; LYR protein (LYRM); leucine-tyrosine-arginine motif containing protein; NFS1; cysteine desulfurase; KAS; ketoacyl-ACPM synthase
Keywords: پیرووات دهیدروژناز; CHF; chronic heart failure; ROS; reactive oxygen species; TGA; triglycerides; FAO; fatty acid β oxidation; PDH; pyruvate dehydrogenase; TCA; tricarboxylic acid; ATP; adenosine triphosphate; ADP; adenosine diphosphate; GDP; guanosine diphosphate; OXPHOS;
Keywords: پیرووات دهیدروژناز; DCA; Dichloroacetate; ECAR; extra cellular acidification rate; JC-1; 5,5â²,6,6â²-tetrachloro-1,1â²,3,3â²-tetraethylbenzimidazolycarbocyanine; MMP; ÎÏm, mitochondrial membrane potential; NAD+; Â nicotinamide adenine dinucleotide; NADH; reduced nicoti
Keywords: پیرووات دهیدروژناز; ATP; adenosine triphosphate; BrP; bromopyruvate; CO2; carbon dioxide; CoA; acetyl-coenzyme A; 2-DG; 2-deoxyglucose; ETC; electron transport chain; FAO; fatty acid oxidation; FAD; flavin adenine dinucleotide; FDG; fluorinated deoxyglucose; FFA; free fatty
Keywords: پیرووات دهیدروژناز; 2-DG; 2-deoxyglucose; 2-HG; 2-hydroxyglutarate; 5mC; 5-methlycystosine; ACACA; acetyl-CoA carboxylase; AML; acute myeloid leukemia; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; ALDH; aldehyde dehydrogenase; ADCs; an
Keywords: پیرووات دهیدروژناز; Allergy; mast cells; degranulation; cytokines; pyruvate dehydrogenase; microphthalmia transcription factor; asthma; mitochondria; AHR; Airway hyperresponsiveness; BALF; Bronchoalveolar lavage fluid; BMMC; Bone marrow-derived mast cell; CBMC; Cord bloodâ
Keywords: پیرووات دهیدروژناز; AAT; aspartate aminotransferase; Ala; alanine; AlaT; alanine aminotransferase; ALD; aldolase; AOA; aminooxyacetate; Asp; aspartate; CS; citrate synthase; 2-DOG; 2-deoxyglucose; DCA; dichloroacetate; DHAP; dihydroxyacetone phosphate; ENO; enolase; Ery4P; e
Keywords: پیرووات دهیدروژناز; 2,2DCPA; 2,2-dichloropropionate; 2MCPA; 2-monochloropropionic acid; 3-BrPA; 3-bromopyruvic acid; 5-FU; 5-fluorouracil; Bcc; Burkholderia cepacia complex; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; DBA; dibromoacetic acid; DCA; dichloroacetic acid; F
Keywords: پیرووات دهیدروژناز; mass spectrometry; molecular phenotyping; post-translational modifications; protein arrays; protein dynamics; protein signatures; AP-MS; affinity purification-mass spectrometry; FDR; false discovery rate; MS; mass spectrometry; PDH; pyruvate dehydrogenas
Keywords: پیرووات دهیدروژناز; diabetes mellitus; diagnostics; energy metabolism; heart failure; ischemic heart disease; obesity; ATP; adenosine triphosphate; BCAA; branched-chain amino acid; BCKA; branched-chain α-keto-acid; BNP; B-type natriuretic peptide; CAD; coronary artery disea
Keywords: پیرووات دهیدروژناز; GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;
Keywords: پیرووات دهیدروژناز; 6-OHDA; 6-hydroxydopamine; ADTIQ; 1-acetyl-6, 7-dihydroxyl-1, 2, 3, 4-tetrahydroisoquinoline; AMPK; 5â²-AMP-activated protein kinase; ATF; activating transcription factor 6; ATM; ataxia telangiectasia mutated; CHOP; CCAAT/-enhancer-binding protein homolo
Keywords: پیرووات دهیدروژناز; AMPK; AMP-activated protein kinase; BM; bone marrow; CAT; catalase; Complex I; NADH-coenzyme Q oxidoreductase; Complex II; succinate-coenzyme Q oxidoreductase; Complex III; ubiquinol-cytochrome c oxidoreductase; COX; cytochrome c oxidase; Complex V; FoF1A
Keywords: پیرووات دهیدروژناز; Ketone bodies; β-Hydroxybutyrate; Pyruvate dehydrogenase; Brain insulin resistance; Fasting; Ketogenic diet; Medium-chain triglyceride; Ketone monoester;
Keywords: پیرووات دهیدروژناز; CRC; colorectal cancer; DCA; dichloroacetate; PDH; pyruvate dehydrogenase; PDK; pyruvate dehydrogenase kinase; MA; mitochondrial activity.; Dichloroacetate; Pyruvate dehydrogenase kinase; Anoxia; Mitochondrial function; Colorectal cancer;
Keywords: پیرووات دهیدروژناز; Blood-brain barrier; Neurovascular unit; Glycolysis; Lactate; Brain development; AGEs; advanced glycation end products; ADP; ribose-adenosine diphosphate ribose; ATP; adenosine triphosphate; BBB; blood-brain barrier; BDNF; brain-derived growth factor; C
Keywords: پیرووات دهیدروژناز; ACLY; ATP citrate lyase; AKT; protein kinase B; ATP; adenosine triphosphate; ANT; adenine nucleotide translocator; AMPK; AMP-activated protein kinase; COX; cytochrome c oxidase; EGFR; epidermal growth factor receptor; ERRα; estrogen-related receptor alph
Keywords: پیرووات دهیدروژناز; ACC; acetyl-coenzyme A carboxylase; ACP; acyl carrier protein; ACPS; acyl carrier protein synthase; ACS; acyl-coenzyme A synthetase; CoA; coenzyme A; DHAP; dihydroxyacetone phosphate; dim; cyclohexanedione; DOXP pathway; 1-deoxy-d-xylulose-5-phosphate/non
Keywords: پیرووات دهیدروژناز; ABE; acetone-butanol-ethanol; ADH; alcohol dehydrogenase; AFEX; ammonia fiber explosion; ALDH; acetaldehyde dehydrogenase; ARAA; arabinose isomerase; ARAB; ribulokinase; ARAD; ribulosephosphate-4-epimerase; CBP; consolidated bioprocessing; CF; co-ferm
Keywords: پیرووات دهیدروژناز; HPA; hypothalamic-pituitary-adrenal; PBS; phosphate-buffered saline; PCA; perchloric acid; PPP; pentose phosphate pathway; depression; prenatal stress; brain glucose metabolism; phosphofructokinase; lactate; pyruvate dehydrogenase;
Keywords: پیرووات دهیدروژناز; HIF1/HIF-1; hypoxia inducible factor-1; VHL; von Hippel-Lindau; HRE; hypoxia response element; CBP; CREB binding protein; MBD; methyl-CpG binding domain; SRA; SET and RING finger-associated; KBS; Kaiso binding site; ANOVA; analysis of variance; FDR; fal
Keywords: پیرووات دهیدروژناز; A-ALD; acetylating acetaldehyde dehydrogenase; ACC; acetyl-CoA carboxylase; acetyl-AMP; acetyladenylate; ACK; acetate kinase; ACL; ATP-citrate lyase; ACS; acetyl-CoA synthetase; ADH; alcohol dehydrogenase; ALD; acetaldehyde dehydrogenase; CAT; carnitine a
Keywords: پیرووات دهیدروژناز; PDC; pyruvate dehydrogenase complex; PDH; pyruvate dehydrogenase; DCA; dichloroacetic acid; Biogenic polyamine; Lactic acidosis; Phenformin; Spermidine;
Keywords: پیرووات دهیدروژناز; HE; hepatic encephalopathy; MHE; minimal hepatic encephalopathy; CLD; chronic liver disease; TCA cycle; tricarboxylic acid cycle; NMR; nuclear magnetic resonance; BDL; bile-duct ligation; DCA; dichloroacetate; PDH; pyruvate dehydrogenase; PC; pyruvate car
Keywords: پیرووات دهیدروژناز; AceCS2; acetyl-CoA synthetase 2; ADP; adenosine diphosphate; CPS1; carbamoyl phosphate synthetase 1; CPT1; carnitine palmitoyltransferase I; CR; calorie restriction; FOXO3a; forkhead box 03a; GDH; glutamate dehydrogenase; HeLa; human cervical carcinoma ce
Keywords: پیرووات دهیدروژناز; BALB; Balb/cJ; Bl6; C57BL/6N; DAG; diacylglycerol; FFA; free fatty acids; FAO; fatty acid oxidation; BCAA; branched-chain amino acids; WAT; white adipose tissue; BAT; brown adipose tissue; ACN; acetonitrile; PPAR-α; peroxisome proliferator-activated rece
Keywords: پیرووات دهیدروژناز; Mitochondria; Human fibroblasts; Human endothelial cells; Hyperglycaemia; Hyperosmosis; GLUT; glucose transporter; TCA; tricarboxylic acid cycle; ETC; electron transport chain; ÎÏm; mitochondrial transmembrane potential; ROS; reactive oxygen species; HD
Keywords: پیرووات دهیدروژناز; ACAA2; 3-oxoacyl-CoA thiolase; ADIPOR; adiponectin receptor; AF1,2; activation function 1,2; AMPK; AMP-activated protein kinase; ATF4; activating transcription factor 4; ATGL; adipose triglyceride lipase; CaMK; calcium/calmodulin-dependent kinase; CD36; f
Keywords: پیرووات دهیدروژناز; ADP; adenosine diphosphate; ALT; alanine aminotransferase; ATP; adenine triphosphate; CoA; coenzyme A; FAD; flavin adenine dinucleotide; FADH2; reduced flavin adenine dinucleotide; GPT; glutamate pyruvate transaminase; HIV; human immunodeficiency virus; L
Keywords: پیرووات دهیدروژناز; AA; arachidonic acid; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; ANT; adenine nucleotide translocase; Apaf-1; apoptotic protease activating factor-1; ATP; adenosine triphosphate; ATP-ase; ATP synthase;
Keywords: پیرووات دهیدروژناز; CSF; cerebrospinal fluid; DCA; dichloroacetate; EDTA; ethylenediaminetetraacetic acid; GSTZ1; glutathione transferase zeta 1; MA; maleylacetone; MAAI; maleylacetoacetate isomerase; MELAS; mitochondrial encephalomyopathy, lactic acidosis and stroke-like ep
Keywords: پیرووات دهیدروژناز; CDK; cyclin; OXPHOS; oxidative phosphorylation; PGC1; peroxisome proliferator-activated receptor-γcoactivator; ROS; reactive oxygen species; PET scan; positron emission tomography; ETC; electron transport chain; PDH; pyruvate dehydrogenase; SV40; simian
Keywords: پیرووات دهیدروژناز; RC; respiratory chain; PDH; pyruvate dehydrogenase; BCAAs; branched chain amino acids; CK; creatine kinase; PC; pyruvate carboxylase; PDHc; pyruvate dehydrogenase complex; Primary human mitochondrial disease; Pyruvate dehydrogenase deficiency; Metabolites
Keywords: پیرووات دهیدروژناز; Ac-CoA; acetyl coenzyme A; GLC; glucose; GLU; glutamate; GLY; glyoxylate; ICIT; isocitrate; MAL; malate; OAA; oxaloacetate; PYR; pyruvate; SUC; succinate; α-KG; α-oxoglutarate; GDH; glutamate dehydrogenase; ICDH; isocitrate dehydrogenase; ICL; isocitrat
Keywords: پیرووات دهیدروژناز; Atg7; autophagy-related gene 7; Bnip 3; Bcl2/adenovirus EIB 19 kD-interacting protein 3; COXIV; cytochrome oxidase subunit IV; GA-K; glutaminase-K; GLUT; glucose transporters; HK; hexokinase; HIF-1α; hypoxia inducible factor-1 alpha; LAMP; lysosome-asso
Keywords: پیرووات دهیدروژناز; ACC; acetyl-CoA carboxylase; ACL; ATP:citrate lyase; ACP; acyl-carrier protein; AGPase; ADP-glucose pyrophosphate; AOX; acyl-CoA oxidase; ARA; arachidonic acid; BE; branching enzymes; CDP-DAG; CDP-diacylglycerol; DAG; diacylglycerol; DGAT; diacylglycerol
Keywords: پیرووات دهیدروژناز; Inositol; Insulin resistance; Diabetes; Polycystic ovary syndrome; Metabolic syndrome; Diabetic neuropathy; AC; adenylyl cyclase; ACC; acetyl-coenzyme A carboxylase; AGEs; advanced glycation end products; AMP; adenosine monophosphate; cAMP; cyclic AMP; AM
Novel approaches in the treatment of diabetic cardiomyopathy
Keywords: پیرووات دهیدروژناز; ACE; angiotensin convertase enzyme; ACEi; angiotensin convertase enzyme inhibitor; ADP; adenosine di phosphate; AGE; advanced glycation end products; AM; adrenomedullin; AMP; adenosine mono phosphate; ARB; angiotensin receptor blocker; ATP; adenosine tri
Adropin regulates pyruvate dehydrogenase in cardiac cells via a novel GPCR-MAPK-PDK4 signaling pathway
Keywords: پیرووات دهیدروژناز; Adropin; Mitochondria; PDK4; GRP19; GPCR; Pyruvate dehydrogenase; Metabolism;
Role of Forkhead Box O (FOXO) transcription factor in aging and diseases
Keywords: پیرووات دهیدروژناز; FOXO; Forkhead box O; DBD; DNA-binding domain; NLS; Nuclear localization sequence; NES; Nuclear export sequence; IRE; Insulin-responsive element; ARDs; Age-related diseases; RTK; Receptor tyrosine kinase; PI3K; Phosphoinositide 3kinase; SGK; Serum and glu