Keywords: Nanosuspension; Spray drying; QbD; Risperidone; Orally dispersible tablet;
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Industry 4.0; In silico; Computer model; Digital twin; Tissue engineering; ATMP; Advanced Therapeutic Medicinal Product; ASME; American Society of Mechanical Engineers; CAD-CAM; Computer Aided Design - Computer Aided Manufacturing; cBiT; compendium for
Keywords: API; active pharmaceutical ingredient; CP; centerpoint; CQA; critical quality attribute; DOE; design of experiments; MBPH; main-compression bottom punch height; MCC; microcrystalline cellulose; MCD; main-compression displacement; MCF; main compression for
Keywords: protein formulation; multivariate analysis; biotechnology; stability; excipients; formulation; quality by design; protein excipient interactions; pharmaceutical sciences; biopharmaceuticals characterization; L-Histidine (PubChem CID: 6274); L-Histidine hy
Keywords: WHO; World Health Organization; UNODC; United Nations Office on Drugs and Crime; CD; conductivity detection; C4D; capacitively coupled contactless conductivity detection; AC-DC; alternating current to direct current; LIF; laser induced fluorescence; BGE;
Keywords: PAT; Process Analytical Technology; QbD; Quality by Design; FDA; Food and Drug Administration; pdf; probability density function; CER; carbon evolution rate; OUR; oxygen uptake rate; EKF; extended Kalman filter; PF; particle filter; PEN; penicillin V; POX
Keywords: Lectins; Molecular farming; Monoclonal antibodies; Plant secondary metabolites; Therapeutic anti-cancer vaccines; APIs; active pharmaceutical ingredients; ADCC; antibody-dependent cellular cytotoxicity; ADCs; antibody-drug conjugates; ATPS; aqueous two-
Keywords: Quality of TCM; Q-marker; Research idea; Research method; Research approach; Practice; TCM; traditional Chinese medicine; QC; quality control; Q-marker; quality marker; LTT; Liujing Toutong tabliets; HPLC-Q/TOF-MS; high performance liquid chromatography q
Keywords: ffc; flowability index; ADMET; absorption distribution metabolism excretion toxicity; IND; investigational new drug; HTS; high throughput screening; API; active pharmaceutical ingredient; QbD; quality by design; MCC 102; microcrystalline cellulose PH 102;
Keywords: AMMS; accurate mass spectrometry; AQbD; analytical quality-by-design; ASME; American Society of Mechanical Engineers; ATP; analytical target profile; CQA; critical quality attributes; DoE; design of experiments; DQ; design qualification; DS; design space;
Keywords: Metabolic flux analysis; Sensitivity analysis; Complex raw material; Filamentous fungi; Corn steep liquor; Key material attributes; ACV; L-α-aminoadipyl-L-cysteinyl-D-valine; CMA; critical material attributes; CPP; critical process parameters; CQA; criti
Keywords: Recombinant therapeutics; Aggregation; Host cell proteins; Glycosylation; Regulation; Biopharmaceuticals; 2D-PAGE; Two-dimensional polyacrylamide gel electrophoresis; ADCC; antibody-dependent cell-mediated cytotoxicity; AUC/SV-AUC; (Sedimentation velocity
Keywords: CCCD; circumscribed central composite design; CQA; critical quality attribute; DOE; design of experiments; QbD; quality-by-design; 3-Fluid nozzle; Design of experiments; Dissolution rate; Lipophilic drug; Poor water solubility; Solid dispersion; Spray dry
Keywords: α-CD; α-cyclodextrin; β-CD; β-cyclodextrin; γ-CD; γ-cyclodextrin; A-β-CD; acetyl-β-CD; BGE; background electrolyte; C4D; capacitively coupled contactless conductivity detection; CD; cyclodextrin; CDTA; cyclohexate-1,2-diaminetetraacetic acid; CE;
Keywords: ADME; absorption distribution metabolism elimination; ASEs; aerosols solvent extractions; AUC; area under curve; BBB; blood-brain barrier; BCS; Biopharmaceutical Classification System; BDP; beclomethasone dipropionate; CFC; critical flocculation concent
Keywords: robustness; quality by design; biopharmaceutical; drug product; formulation; manufacturing process; design space; BLA; biological license application; BPDG-FPS; Biophorum Development Group-Formulation Point Share; CQA; critical quality attribute; CPP; c
Keywords: QbD; Biorelevant dissolution; IVIVC; Ethanol; Design of experiments; Multivariate data analysis;
Keywords: CHO; Chinese hamster ovary; DCC; dead cell count; DoE; design of experiment; NRMSE; normalized root-mean-square error; VCC; viable cell count; ANN; artificial neural network; Glu; glutamine; Glc; glucose; Lac; lactate; NH4; ammonia; LS; limiting substrate
Keywords: HTA; Health Technology Assessment; HSE; Health Safety Environment; GMP; Good Manufacturing Practice; EBM; Evidence Based Medicine; QS; Quality System; FP; Finished Product; QbD; Quality By Design; API; Active Pharmaceutical Ingredient; FTE, PAT; Process A
Keywords: API; active pharmaceutical ingredient; BET; Brunauer, Emmett, Teller; DVS; dynamic vapor sorption; HPC; hydroxypropyl cellulose; HPMC; hydroxypropyl methylcellulose; L/S; liquid-to-solid; LOD; loss on drying; Log; logarithmical; MCC; microcrystalline cell
Keywords: CBM; Constraint-based modeling; CHO; Chinese hamster ovarian; ER; Endoplasmic reticulum; FBA; Flux balance analysis; GFA; Glycosylation flux analysis; IgG; Immunoglobulin G; MFA; Metabolic flux analysis; PAT; Process analytical technology; QbD; Quality by
Keywords: QbD; Antioxidants; Phytomolecule; Molecular docking; P-gp efflux; Caco-2 bidirectional permeability assay; SPIP;
Keywords: DoE; design of experiments; GMP; good manufacturing practice; HCPs; host cell proteins; QbD; quality by design; Bioprocess design; Convective and conductive heat transfer; Downstream processing; Heat precipitation of host cell proteins; Modeling; Optimiza
Keywords: biotechnology; formulation; HPLC; multivariate analysis; oxidation; factorial design; protein aggregation; protein formulation; proteins; stability; AC; acceptance criterion; Buff; buffer concentration; CQA; critical quality attribute; CI; confidence inte
Keywords: Liposomes; Vaccines; Adjuvants; Antigens; Delivery systems; Microfluidics; QbD; MVA
Keywords: QbD; quality by design; DoE; Design of Experiments; QTTP; quality target product profile; WIV; whole inactivated influenza virus; XRD; X-ray diffractometry; DSC; differential scanning calorimetry; RMC; residual moisture content; Spray drying; Process opti
Keywords: Pharmaceutical manufacturing; Secondary manufacturing; Quality by design; Process analytical technology; PAT; QbD
Keywords: 2D-LC; two-dimensional liquid chromatography; AA; amino acid; AC; affinity chromatography; ADC; antibody-drug conjugates; ADCC; antibody-dependent cellular cytotoxicity; AF4; asymmetric flow field fractionation; APTS; 1-aminopyrene-3,6,8-trisulfonate; Asn
Keywords: API; active pharmaceutical ingredient; Cmax; maximum plasma concentration; CQA; critical quality attribute; CPP; critical process parameter; EMA; European Medicines Agency; FDA; U.S. Food and Drug Administration; FPF; fine particle fraction; ICH; Internat
Keywords: Quality by Design; QbD; Food processing; Bioprocessing; Biotech therapeutics; Process Analytical Technology; PAT;
Keywords: Wet granulation; High-shear; DOE; QbD; Particle size; Porosity; Process parameter
Keywords: Powder bulk density; NIR; Real time monitoring; PAT; Feed-forward control; QbD;
Keywords: Multimodal; Mixed-mode; QbD; DoE; Optimization strategy; Malaria vaccine
Keywords: Ibuprofen lysine salt (PubChem CID: 9,841,440); Acetaminophen (PubChem CID: 1983); Tramadol hydrochloride (PubChem CID: 63,013); Heckel; Yield pressure; PAT; QbD; Tablets; Compression;
Keywords: Dry powder inhaler (DPI); Amikacin; Cystic fibrosis; Half-fractional factorial design; Orally inhaled drug product (OIDP); AMK; Amikacin; DPI; Dry Powder Inhaler; QbD; Quality by Design; DoE; Design of Experiments; CQAs; Critical Quality Attributes; CPPs;
Keywords: computational fluid dynamics; enzymes; fluorescence spectroscopy; freezing/thawing; HPLC; protein aggregation; protein folding; protein stability; thermal analysis; ANS; 8-anilino-1-naphthalenesulfonic acid; BSA; bovine serum albumin; F/T; freezing and th
Keywords: Design space; Process robustness; Ethanol precipitation; Danhong injection; Quality by design; AC; active ingredient content (mg gâ1); ACR; active ingredient recovery (%); AEA; the amount of ethanol added (mL gâ1); ANOVA; analysis of variance; ARD;
Keywords: Micronization; Milling; QbD; Blending; Surface energy; Surface area; Cohesion
Quality by design approach for development and validation of a RP-HPLC method for simultaneous determination of co-administered levetiracetam and pyridoxine HCl in prepared tablets
Keywords: QbD; Levetiracetam; Pyridoxine HCl; HPLC-DAD; Prepared tablets;
A Quality by Design (QbD) approach to the development of a gradient high-performance liquid chromatography for the simultaneous assay of curcuminoids and doxorubicin from long-circulating liposomes
Keywords: Curcumin; Demetoxycurcumin; Bisdemetoxycurcumin; Doxorubicin; Long-Circulating Liposomes; QbD; DoE; Response surface;
Development of TCM-based composite particles for direct compaction by particle design
Keywords: Direct compaction; Design of experiment; Compactibility; Flowability; Yield; Traditional Chinese medicine; AHE; Andrographis herba extract; API; active pharmaceutical ingredient; AR; angle of repose; AUTCC; area under the tensile strength versus compactio
Dual mechanism of microenvironmental pH modulation and foam melt extrusion to enhance performance of HPMCAS based amorphous solid dispersion
Keywords: API; active pharmaceutical ingredient; ASD; amorphous solid dispersion; HME; Hot-melt extrusion; HPMCAS; Hydroxypropyl methylcellulose acetate succinate; PAT; Process Analytical Technology; QbD; Quality by Design; Foam melt extrusion; Amorphous solid disp
Downscaling of the tableting process: Feasibility of miniaturized forced feeders on a high-speed rotary tablet press
Keywords: ART; average residence time; CCW; counterclockwise; CP; centerpoint; CW; clockwise; DOE; design of experiments; MBPH; main-compression bottom punch height; MCC; microcrystalline cellulose; MCD; main compression displacement; MCF; main compression force; M
Revisiting in vitro release test for topical gel formulations: The effect of osmotic pressure explored for better bio-relevance
Keywords: EGF; epidermal growth factor; T/B; trypan blue; QbD; quality by design; DOE; design of experiment; PBS; phosphate buffered saline; PG; poloxamer gel; P407; poloxamer 407; P188; poloxamer 188; PDGF; platelet derived growth factor; Thermoreversible gel; Des
Dry powder inhalers: An overview of the in vitro dissolution methodologies and their correlation with the biopharmaceutical aspects of the drug products
Keywords: Pulmonary delivery; Dry powder inhalation; Solubility; Dissolution methods; Biopharmaceutical classification; API; Active pharmaceutical ingredient; ACI; Andersen cascade impactor; ALF; alveolar lung fluid; BCS; Biopharmaceutics Classification System; iBC
Hot-melt coating with Precirol ATO 5 in a fluidized-bed apparatus: Application of experimental design in the optimization of process parameters
Keywords: Granules; Paracetamol; Glycerol distearate; Size distribution; Flowability; Drug release; AAP; atomization air pressure; AUC; area under the drug release curve; BCS; Biopharmaceutics Classification System; CI; compressibility index; CPP; critical process
An overview of experimental designs in HPLC method development and validation
Keywords: 2D-HPLC; two-dimensional HPLC; AEMC; anion-exchange membrane chromatography; ANOVA; analysis of variance; BBD; Box-Behnken design; CC; chaotropic chromatography; CCD; central composite Design; CEX-HPLC; cation exchange high performance liquid chromatograp
A quality by design (QbD) twin-Screw extrusion wet granulation approach for processing water insoluble drugs
Keywords: Wet granulation; DoE; QbD; Dissolution rate; Specific surface area; Water sorption;
Quality by Design (QbD)-enabled development of aceclofenac loaded-nano structured lipid carriers (NLCs): An improved dermatokinetic profile for inflammatory disorder(s)
Keywords: NLCs; Nanostructured lipid carriers; SLNs; Solid lipid nanoparticles; CA; Cetyl alcohol; QbD; Quality by Design; FbD; Formulation by Design; CQA; Critical Quality Attributes; CMA; Critical Material Attributes; CFA; Critical Formulation Attributes; Opt; Op
Natural lipids enriched self-nano-emulsifying systems for effective co-delivery of tamoxifen and naringenin: Systematic approach for improved breast cancer therapeutics
Keywords: SNEDDS; Self-nano-emulsifying drug delivery systems; Smix; Surfactant mix; TMX; Tamoxifen; NG; Neringenin; PUFA; Polyunsaturated fatty acids; GIT; Gastrointestinal tract; Opt; Optimized; QbD; Quality by design; DoE; Design of experiment; CQA; Critical qua