Keywords: خواندن در سراسر; Aryl alcohol alkyl carboxylic acid esters; Read-across; Similarity; Uncertainty; Repeated-dose toxicity;
مقالات ISI خواندن در سراسر (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: خواندن در سراسر; Grouping concept; Read-across; Aquatic ecotoxicity; Nanomaterials; Risk assessment;
Keywords: خواندن در سراسر; Active pharmaceutical ingredient; Predictive model; Read-across; Water-fish-osprey food chain; Wildlife;
Keywords: خواندن در سراسر; Strategies; Tiered testing; Vitro-vivo comparison; Bioaccumulation; Delivered dose; Read-across; Decision-making;
Keywords: خواندن در سراسر; QSAR; Read-across; Acute oral toxicity; ICCVAM; Workshop;
Keywords: خواندن در سراسر; Read-across; Toxicity; Adrenergic; Epinephrine; Norepinephrine;
Keywords: خواندن در سراسر; Lower methacrylate esters; Health effects; Category approach; Read-across; Fill in data gaps;
Keywords: خواندن در سراسر; Read-across; Similarity; Uncertainty; Case studies; Repeated-dose toxicity; Regulatory acceptance;
Keywords: خواندن در سراسر; Read-across; Analog identification; Analog evaluation; Quantitative uncertainty analysis; Estrogen receptor (ER) binding;
Keywords: خواندن در سراسر; Read-across; Mono-alkylphenols; Repeated-dose toxicity; No Observed Adverse Effect Level (NOAEL); Lowest Observed Adverse Effect Level (LOAEL); Weight-of-evidence (WoE); Uncertainty;
Keywords: خواندن در سراسر; Read-across; n-Alkanols; Repeated-dose toxicity; No Observed Adverse Effect Level (NOAEL); Lowest Observed Adverse Effect Level (LOAEL); Weight-of-evidence (WoE); Uncertainty;
Keywords: خواندن در سراسر; Category approach; Analogue approach; Data gap filling; Read-across; (Q)SAR; Trend analysis; Nearest neighbours;
Keywords: خواندن در سراسر; Read-across; Nearest neighbors; Local validity domains; (Q)SAR; KNN; Bioactivity; ToxCast;
Keywords: خواندن در سراسر; Nanomaterials; Risk assessment approach; Prioritisation; Grouping; Read-across; (Q)SARs; Testing strategy;
Keywords: خواندن در سراسر; Neural crest; Migration; Read-across; Chemical grouping; Gene expression; HDAC inhibitors; Pesticides; Metals; PCBs; Pathways of toxicity; Toxicology
Keywords: خواندن در سراسر; Scientific confidence framework (SCF); Adverse outcome pathway (AOP); Mode of action (MoA); Integrated approaches to testing and assessment (IATA); (Q)SAR; Read-across; Exposure:activity ratio (EAR);
Keywords: خواندن در سراسر; Read-across; Similarity; Uncertainty; Chemical analogue identification; Prediction; Toxicity; Regulatory acceptance; OECD; REACH;
Keywords: خواندن در سراسر; Read-across; (Quantitative) Structure Activity Relationship (Q)SAR; Quantitative Mechanistic Models (QMM); Chemical categories; Analogue approach; Adverse Outcome Pathway (AOP); Scientific confidence;
Keywords: خواندن در سراسر; Alternative method; Risk assessment; Quantitative structure activity relationship (QSAR); Toxicity; Cancer potency (TD50); Genotoxicity; Read-across;
Keywords: خواندن در سراسر; CEN; European Committee for Standardization; CLP; classification, labeling and packaging of substances and mixtures regulation; RBA; relative bioavailability; ECHA; European Chemicals Agency; RBALP; relative bioaccessibility leaching procedure; REACH; Reg
Keywords: خواندن در سراسر; Cell lines; 3Rs; QSAR; Read-across; Exposure-based waiving; Fish embryo test; Acute toxicity; Chronic toxicity; Endocrine disruption; Bioconcentration;
Mechanism-informed read-across assessment of skin sensitizers based on SkinSensDB
Keywords: خواندن در سراسر; Adverse outcome pathway; Skin sensitizer; Read-across; SkinSensDB;
Structure activity relationship (SAR) toxicological assessments: The role of expert judgment
Keywords: خواندن در سراسر; Structure activity relationship (SAR); Expert judgement; Similarity; Analog rating; Read-across;
“Simulated gastric hydrolysis and developmental toxicity of dioctyltin bis(2-Ethylhexylthioglycolate) [DOTE] in rabbits and mice”
Keywords: خواندن در سراسر; Teratology; Mouse; Mice; Rabbit; Dioctyltin bis(2-ethylhexylthioglycolate); Read-across; Metabolism; Developmental; gestation[al]; Gastric hydrolysis; CAS 15571-58-1;
Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected n-alkanols
Keywords: خواندن در سراسر; Read-across; n-Alkanols; Repeated-dose toxicity; No Observed Effect Level (NOEL); Lowest Observed Effect Level (LOEL); Weight-of-evidence (WoE); Uncertainty;
Use of read-across to simplify the toxicological assessment of a complex mixture of lysimeter leachate metabolites on the basis of chemical similarity and ADME behavior
Keywords: خواندن در سراسر; Lysimeter; S-metolachlor; ADME; Relevance; Read-across;
New studies on the in vitro genotoxicity of sodium molybdate and their impact on the overall assessment of the genotoxicity of molybdenum substances
Keywords: خواندن در سراسر; Molybdenum; Molybdate; Genotoxicity; Mutation; Clastogenicity; Aneugenicity; Review; In vitro; Read-across;
Quantifying the benefits of using read-across and in silico techniques to fulfill hazard data requirements for chemical categories
Keywords: خواندن در سراسر; In silico; Category approach; Read-across; Trend analysis; (Q)SAR; HPV; Animal alternatives;
Dose-dependent DNA adduct formation by cinnamaldehyde and other food-borne α,β-unsaturated aldehydes predicted by physiologically based in silico modelling
Keywords: خواندن در سراسر; α,β-Unsaturated aldehydes; Cinnamaldehyde; DNA adducts; Physiologically based kinetic/dynamic modelling; Read-across; Genotoxicity;
Mode of action based risk assessment of the botanical food-borne alkenylbenzene apiol from parsley using physiologically based kinetic (PBK) modelling and read-across from safrole
Keywords: خواندن در سراسر; Apiol; Safrole; PBK modelling; Read-across; Risk assessment; Margin of exposure; ADD; 4-allyl-3,6-dimethoxybenzene-1,2-diol; BMDL10; the lower confidence limit of the benchmark dose resulting in a 10% extra cancer; DHA; 2â²,3â²-di hydroxyapiol; DMSO; di
Case studies putting the decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping) into practice
Keywords: خواندن در سراسر; Carbonaceous nanomaterials; Metal oxide and metal sulphate nanomaterials; Amorphous silica nanomaterials; Organic pigments; Grouping; Read-across; Intrinsic material and system-dependent properties; Biopersistence and biodistribution; Cellular effects; Ap
Use of read-across and computer-based predictive analysis for the safety assessment of PEG cocamines
Keywords: خواندن در سراسر; CIR; Cosmetic Ingredient Review; GD; gestation day; LOAEL; lowest observed adverse effect level; NOAEL; no observed adverse effect level; NOEL; no observed effect level; PEG; polyethylene glycol; SAR; structure-activity relationship; SOI; structure of i
From single chemicals to mixtures-Reproductive effects of levonorgestrel and ethinylestradiol on the fathead minnow
Keywords: خواندن در سراسر; Fathead minnow; EE2; Levonorgestrel; Mixtures toxicity; Read-Across; Reproduction;
A decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping)
Keywords: خواندن در سراسر; AOP; adverse outcome pathway; APPIE; Association of Powder Process Industry; ASTM; American Society for Testing and Materials; ATP; adenosine triphosphate; BAM; German Federal Institute for Materials Research and Testing; BAuA; German Federal Institute fo
The challenge of using read-across within the EU REACH regulatory framework; how much uncertainty is too much? Dipropylene glycol methyl ether acetate, an exemplary case study
Keywords: خواندن در سراسر; Read-across; REACH; Dipropylene glycol methyl ether acetate (DPMA); CAS No. 88917-22-0; Uncertainty;
Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)
Keywords: خواندن در سراسر; Adverse Outcome Pathway (AOP); Integrated Approaches to Testing and Assessment (IATA); (Q)SAR; Read-across; High throughput screening (HTS); High content screening (HCS); Cross species extrapolation;
Towards AOP application - Implementation of an integrated approach to testing and assessment (IATA) into a pipeline tool for skin sensitization
Keywords: خواندن در سراسر; Adverse Outcome Pathway (AOP); Integrated Approaches to Testing and Assessment (IATA); Expert systems; TIMES-SS; (Q)SAR; Read-across;
Use of category approaches, read-across and (Q)SAR: General considerations
Keywords: خواندن در سراسر; Category approach; Analogue approach; Read-across; Data gap filling; (Q)SAR; REACH;
The OSIRIS Weight of Evidence approach: ITS mutagenicity and ITS carcinogenicity
Keywords: خواندن در سراسر; Bayes' theorem; Carcinogenicity; Decision theory; In vitro; In vivo; Mutagenicity; QSARs; Read-across; Swing weighting; Testing strategies;
A comparative survey of chemistry-driven in silico methods to identify hazardous substances under REACH
Keywords: خواندن در سراسر; QSARs; Read-across; Structural alerts; Applicability domain; Consensus; Cost-efficiency; PBT; CMR; Endocrine disruption; Skin sensitisation;
Mode of action of human pharmaceuticals in fish: The effects of the 5-alpha-reductase inhibitor, dutasteride, on reproduction as a case study
Keywords: خواندن در سراسر; Pharmaceutical; Anti-androgen; 5-Alpha reductase; Fish; Read-across; Reproductive toxicology
Acute oral toxicity of nickel compounds
Keywords: خواندن در سراسر; Nickel; Metal; Acute toxicity; Oral; REACH; Read-across; Rat; Classification; Bioavailability; Bioaccessibility
Oral bioaccessibility testing and read-across hazard assessment of nickel compounds
Keywords: خواندن در سراسر; Nickel; Metal; Acute toxicity; Oral; REACH; Read-across; Rat; Classification; Bioavailability; Bioaccessibility;
Development of new structural alerts suitable for chemical category formation for assigning covalent and non-covalent mechanisms relevant to DNA binding
Keywords: خواندن در سراسر; Chemical category formation; Structural alerts; In silico profiler; Covalent DNA binding; Non-covalent DNA binding; Read-across;
Use of read-across and tiered exposure assessment in risk assessment under REACH – A case study on a phase-in substance
Keywords: خواندن در سراسر; REACH; Risk assessment; Read-across; Grouping; Tiered exposure assessment
A multivariate chemical map of industrial chemicals – Assessment of various protocols for identification of chemicals of potential concern
Keywords: خواندن در سراسر; Hazard identification; Persistent organic pollutants; Risk assessment; Molecular similarities; Non-testing methods; Read-across