Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; Alternatives to animal testing; QIVIVE; Regulatory acceptance; Food toxicology; Drivers and barriers; Multilevel perspective on technology transitions; 3R; replace, reduce, or refine; EFSA; European Food Safety Authority; EU; European Union; PBPK; physiol
مقالات ISI ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی (ترجمه نشده)
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Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; Ascophyllum nodosum extract; Tomato; Drought stress; Dehydrin; Osmolytes; Plant biostimulant; Abiotic stress tolerance; 2-ME; 2-mercapthoethanol; ABA; abscisic acid; ANE; Ascophyllum nodosum extract; DW; dry weight; EBIC; European Biostimulant Industry Co
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; Acute inhalation toxicity; In vitro; In silico; Ex vivo; Quantitative structure-activity relationships (QSAR); Adverse outcome pathway; Aggregate exposure pathway; Dosimetry; Integrated approach to testing and assessment (IATA); Risk assessment; ADME; abs
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; Microbial based cleaning products; MBCPs; Microbial cleaner; Probiotic cleaner; Risk assessment; Safety assessment; Risk management; Ecolabelling; BEUC; Bureau Européen des Unions de Consommateurs CCPSA; Canada Consumer Product Safety Act; CEPA; Canadian
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; Sustainability criteria; Sustainable product development; Sustainability integration; Sustainability implementation; Decision support; ACARE; Advisory Council for Aeronautics Research in Europe; DRM; Design Research Methodology; ECM; Electro-Chemical Mill
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; BMI; body mass index; EPA; environmental protection agency; GM; geometric mean; LC; liquid chromatography; LOD; limit of detection; LOQ; limit of quantification; MS; mass spectrometry; PFAA; perfluorinated alkyl acid; PFBS; perfluorobutane sulfonate; PFCA
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; DNA damage; Vitotox®; In silico; ECHA database; Food contact materials; Polycarbonate replacement products; BaP; benzo[a]pyrene; BPA; bisphenol A; CLP; Classification, Labelling and Packaging; ECHA; European CHemicals Agency; 4-NQO; 4-Nitroquinoline 1-ox
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; ANF; Asia Nano Forum; ASEAN; Association of South East Asian Nations; CoE; Center of Excellence; DOST; Department of Science and Technology; EDB; Economic Development Board; EHS; Environmental health and safety; EU; European Union; ICON; Industry Consorti
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; Uses of lime; Trade; Lime industry; Environmental remediation; Healthcare solutions; Metallurgy applications; REACH; Registration, Evaluation, Authorisation and Restriction of Chemicals; IPPC; International Plant Protection Convention; BAT; Best Available
Regulatory identification of BPA as an endocrine disruptor: Context and methodology
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; Bisphenol A; Endocrine disruption; ED; SVHC; Substance of very high concern; REACh; ANSES; Agence Nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du travail (French Agency for Food, Environmental and Occupational Health & Sa
CON4EI: Development of serious eye damage and eye irritation testing strategies with respect to the requirements of the UN GHS/EU CLP hazard categories
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; BCOP; Bovine Corneal Opacity and Permeability; CON4EI; CONsortium for in vitro Eye Irritation testing strategy; EpiOcular⢠EIT; EpiOcular Eye Irritation Test; EpiOcular⢠ET-50; EpiOcular Time-to-toxicity; EU CLP; European Union Regulation on Classific
Evidence-based adverse outcome pathway approach for the identification of BPA as en endocrine disruptor in relation to its effect on the estrous cycle
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; Bisphenol A; Endocrine disruption; Female reproduction; Estrogen; â; increase; â; decrease; 2G; 2-generation study; 3G; 3-generation study; ANSES; Agence Nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du travail, (French Ag
Finding synergies for 3Rs - Toxicokinetics and read-across: Report from an EPAA partners' Forum
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; Physiologically-based kinetic (PBK) modelling; Hazard and risk assessment; Weight-of-evidence (WoE); Threshold of toxicological concern (TTC); In vitro to in vivo extrapolation (IVIVE); Integrated approach for testing and assessment (IATA); Absorption; Di
Are some “safer alternatives” hazardous as PBTs? The case study of new flame retardants
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; AD; applicability domain; BCF; bioconcentration factor; BDBP-TAZTO; 1.3-bis(2,3-dibromopropyl)-5-allyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; BFR; brominated flame retardants; bor AD; borderline applicability domain; BPA-BDPP; bisphenol A tetraphenyl diph
A new integrated in silico strategy for the assessment and prioritization of persistence of chemicals under REACH
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; REACH; Registration, Evaluation, Authorisation and restriction of CHemicals; P; persistent; nP; non-persistent; vP; very persistent; nP/P; non-persistent/persistent; P/vP; persistent/very persistent; HL; half-lives; DT50; disappearance time 50; PBT; persi
Integrated in silico strategy for PBT assessment and prioritization under REACH
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; REACH; Registration, Evaluation, Authorisation and Restriction of Chemicals; (Q)SAR; (quantitative) structure-activity relationship; ECHA; European Chemicals Agency; UBA; Umweltbundesamt; MCDM; multi-criteria decision making; WoE; weight of evidence; AD;
Aligning the 3Rs with new paradigms in the safety assessment of chemicals
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; 3Rs; replacement, refinement and reduction of animals in research; AOP; adverse outcome pathway; EURL-ECVAM; European Union Reference Laboratory for Alternatives to Animal Testing; ICCVAM; Interagency Coordinating Committee on the Validation of Alternativ
Dose metric considerations in in vitro assays to improve quantitative in vitro-in vivo dose extrapolations
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; AUC; Area under the curve; TWA; Time weighted average; BED; Biologically effective dose; EC50; Median effect concentration; MeOA; Mechanism of action; PBBK; Physiological based biokinetic modelling, also referred to in literature as physiological based ph
Long lasting perfume - A review of synthetic musks in WWTPs
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; Synthetic musks; Wastewater treatment plants; Removal efficiency; 2-AMK; 2-amino musk ketone; 2-AMX; 2-amino musk xylene; 4-AMX; 4-amino musk xylene; ADBI; celestolide; AETT; versalide; AHMI; phantolide; AHTN; tonalide; ATII; traseolide; DPMI; cashmeran;
Estimation of the chemical-induced eye injury using a weight-of-evidence (WoE) battery of 21 artificial neural network (ANN) c-QSAR models (QSAR-21): Part I: Irritation potential
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; 3Rs; refinement, reduction and replacement; AD; applicability domain; ADME; absorption, distribution, metabolism, and excretion; ANN; artificial neural network; ANNE; artificial neural network ensemble; Architecture; particular combination of neurons and
Combining the European chemicals regulation and an (eco)toxicological screening for a safer membrane development
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; REACH regulation; European chemical policy; (Eco)toxicological assessment; Polymeric membrane; CLP; Classification, Labelling and Packaging; CMR; carcinogenic, mutagenic and toxic for reproduction; DMA; N,N-Dimethylacetamide; DMSO; dimethyl sulfoxide; ECH
Sub-categorisation of skin corrosive chemicals by the EpiSkin⢠reconstructed human epidermis skin corrosion test method according to UN GHS: Revision of OECD Test Guideline 431
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; BLR; Between-laboratory reproducibility; ECHA; European Chemicals Agency; ESAC; ECVAM Scientific Advisory Committee; EU; European Union; EU CLP; European Union System of Classification of Chemicals implemented in the EU Classification, Labelling and Packa
A structured approach to Exposure Based Waiving of human health endpoints under REACH developed in the OSIRIS project
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; ADME; absorption, distribution, metabolism, excretion; DNEL; Derived no effect level; EBW; Exposure Based Waiving; EBT; Exposure Based Triggering; ITS; Integrated testing strategy; KOW; n-octanol-water partition coefficient; MMAD; Mass median aerodynami
Risk assessment of endocrine active chemicals: Identifying chemicals of regulatory concern
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; ACR; acute-to-chronic ratio; BfR; Bundesinstitut für Risikobewertung (German regulatory body); CLP; Classification, Labelling and Packaging; CRD; Chemicals Regulation Directorate (UK regulatory body); ECETOC; European Centre for Ecotoxicology and Toxicol
Assessment strategies and decision criteria for pesticides with endocrine disrupting properties relevant to humans
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; ADI; acceptable daily intake; BfR; Bundesinstitut für Risikobewertung (German Federal Institute for Risk Assessment); CMR; carcinogenic, mutagenic, or reprotoxic; DES; diethylstilbestrol; DIT; developmental immunotoxicity; DNT; developmental neurotoxicit
Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA industry sectors
Keywords: ثبت، ارزیابی، مجوز و محدودیت مواد شیمیایی; ADME; absorption, distribution, metabolism, and excretion; ADI; Acceptable Daily Intake; Colipa; the European Cosmetic Toiletry and Perfumery Association; CYPs; cytochrome P450s; DNEL; Derived No Effect Level; DG; Directorate General; ECHA; EU Chemicals A