Keywords: AGEs; advanced glycation end products; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; GCL; glutamate cysteine ligase; GSH; glutathione; HO-1; heme oxyge
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Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins
Keywords: 2-NBDG; 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2- Deoxyglucose; 3-MA; 3-Methyladenine; ACC; Acetyl-CoA Carboxylase; Ad; adenoviruses; AKT; Protein Kinase B, also known as AKT; AMPK; Adenosine 5â²-monophosphate (AMP)-activated protein kinase; AT
Re-evaluating the role of FOXOs in cancer
Keywords: RTK; receptor tyrosine kinase; GF; growth factor; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKB; protein kinase B; AKT; RAC-alpha serine/threonine-protein kinase; FOXO; forkhead box O; GFR; growth factor receptor; PDPK1; Phosphoinositide-depen
Redox regulation of proteasome function
Keywords: Abcd1; ATP binding cassette subfamily D member 1; AD; Alzheimer's disease; ALD; adrenoleukodystrophy; ALS; amyotrophic lateral sclerosis; AP-1; activator protein-1; APP; amyloid precursor protein; CNS; central nervous system; DDI; DNA-damage inducible 1;
Activating transcription factor 6-dependent sestrin 2 induction ameliorates ER stress-mediated liver injury
Keywords: Ad; adenovirus; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATF6; activating transcription factor 6; ChIP; chromatin immunoprecipitation; CHOP; C/EBP homologous protein; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxid
The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1
Keywords: Sesn; sestrin; ROS; reactive oxygen species; Prx; peroxiredoxin; Srx; sulfiredoxin; ERK; extracellular signal-regulated kinase; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; mTORC1; mechanistic target of ra