Keywords: مبدل سیگنال و فعال کننده رونویسی; Mushroom; Anti-inflammatory activity; In vitro model; Animal model; Chemopreventive property; Therapeutic potential; CD; Crohn's disease; ConA; concanavalin A; COX-1; cyclooxygenase-1; COX-2; cyclooxygenase-2; DAI; disease activity index; DSS; dextran s
مقالات ISI مبدل سیگنال و فعال کننده رونویسی (ترجمه نشده)
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Keywords: مبدل سیگنال و فعال کننده رونویسی; AAC; abdominal aortic constriction; ADAMS; a disintegrin and metalloproteases; ADAMTS; a distingetrin and metalloproteinase with a thrombospondin domain; Ang II; angiotensin II; BM; basement membrane; BMP-1; bone morphogenic protein-1; CITP; carboxy-termi
Keywords: مبدل سیگنال و فعال کننده رونویسی; JAK; Janus kinase; STAT; signal transducers and activators of transcription; EPOR; erythropoietin receptor; TPOR; thrombopoietin receptor; G-CSFR; granulocyte colony stimulating factor receptor; γc; common gamma chain; SCID; severe combined immunodeficie
Keywords: مبدل سیگنال و فعال کننده رونویسی; AECs; Alveolar endothelial cells; APC; Antigen-presenting cells; BM; Bone marrow; BMSC; Bone marrow- derived mesenchymal stem cells; CIA; Collagen induced arthritis; DCs; Dendritic cells; DCOVA; OVA-specific dendritic cell; DNA; Deoxyribonucleic acid; DTH
Keywords: مبدل سیگنال و فعال کننده رونویسی; OASL; 2'-5'-oligoadenylate synthetase; PKR; double-stranded RNA-dependent protein kinase; GAS; gamma-activated site; HCMV; human cytomegalovirus; ISG; IFN-I-stimulated genes; IFNAR; interferon alpha receptor; IFNGR; interferon gamma receptor; IRF; interfe
Keywords: مبدل سیگنال و فعال کننده رونویسی; AP-1; activator protein 1; APC; antigen-presenting cells; ARE; AU-rich element; ASK; Apoptosis Signal regulating Kinase; ATF-2; Activating Transcription Factor 2; CRE; Cyclic AMP Responsive Element; CBP; CREB binding protein; CsA; ciclosporin A; ERK; Extr
Keywords: مبدل سیگنال و فعال کننده رونویسی; AKT; protein kinase B; ATM; ataxia-telangiectasia mutated; ELISA; enzyme-linked immunosorbent assay; EMT; epithelial-mesenchymal transition; ERK; extracellular signal-regulated kinase; GSK; glycogen synthase kinase; hSAEC; human small airway epithelial
Keywords: مبدل سیگنال و فعال کننده رونویسی; KCs; kupffer cells; JNKs; C-Jun N-terminal kinases; MAPKs; mitogen-activated protein kinases; CCR2; C-C motif chemokine receptor 2; ATMs; Adipose tissue macrophages; HFD; high-fat diet; MLK3; mixed-lineage kinase 3; PPAR; peroxisome proliferator-activat
Keywords: مبدل سیگنال و فعال کننده رونویسی; Azithromycin; Macrolide antibiotic; Mechanisms of action; Pharmacokinetics; Immunomodulation; Clinical efficacy; AECOPD; acute exacerbations of COPD; AP-1; activator protein-1; ARDS; acute respiratory distress syndrome; AUC; area under the plasma concentr
Keywords: مبدل سیگنال و فعال کننده رونویسی; Carotenes; Xanthophylls; NF-κB; Nrf2; Transcription factors; Chronic diseases; AMD; age-related macular degeneration; ARE; antioxidant response element; BCDO2; β-carotene dioxygenase 2; BCO1; β-carotene 15,15â²-oxygenase 1; CAT; catalase; CCL2; chemok
Keywords: مبدل سیگنال و فعال کننده رونویسی; Akt; protein kinase B; AP-1; activator protein 1; ARNT; aryl hydrocarbon receptor nuclear translocate; ATP5F1; ATP synthase H+ transporting mitochondrial Fo complex-subunit B1; CAV1; caveolin-1; CDKs; cyclin dependent protein kinases; CHM; Chinese herbal
Keywords: مبدل سیگنال و فعال کننده رونویسی; APC; adenomatous polyposis coli; bFGF; basic fibroblast growth factor; Ca2Â +i; intracellular calcium; Ca2Â +o; extracellular calcium; CaSR; calcium sensing receptor; CDX-2; caudal type homeobox 2; EGF; epidermal growth factor; ERK; extracellular-signal-r
Leptin in autoimmune mechanisms of systemic rheumatic diseases
Keywords: مبدل سیگنال و فعال کننده رونویسی; Leptin; Connective tissue diseases; Adipokines; Inflammatory arthritis; Vasculitis; WAT; white adipose tissue; IL; interleukin; BMI; body mass index; PPAR; peroxisome proliferator-activated receptor; JAK; janus kinases; STAT; signal transducers and activa
STAT3 Mediates Nilotinib Response in KIT-Altered Melanoma: A Phase II Multicenter Trial of the French Skin Cancer Network
Keywords: مبدل سیگنال و فعال کننده رونویسی; AE; adverse event; AKT; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; CI; confidence interval; CR; complete response; GIST; gastrointestinal stromal tumors; JAK; Janus kinase; MAPK; mitogen-activated protein kinase; OS; overall survival;
CD146 mediates an E-cadherin-to-N-cadherin switch during TGF-β signaling-induced epithelial-mesenchymal transition
Keywords: مبدل سیگنال و فعال کننده رونویسی; E-cadherin; epithelial cadherin; N-cadherin; neuronal cadherin; EMT; epithelial-mesenchymal transition; EMT-TF; EMT transcriptional factor; TGF-β; transforming growth factor-β; BMP; bone morphogenetic protein; MEF; mouse embryonic fibroblast; WT; wild t
Flaviviridae virus nonstructural proteins 5 and 5A mediate viral immune evasion and are promising targets in drug development
Keywords: مبدل سیگنال و فعال کننده رونویسی; AAF; IFN-α-activated factor; ATA; Aurintricarboxylic acid; BDV; border disease virus; BPgV; GBV-D; BVDV-1; bovine viral diarrhea virus-1; C; capsid protein; CLRs; C-type lectin receptors; Core; core protein; CSFV; classical swine fever virus; DENV; dengu
Autophagy as a pharmacological target in hematopoiesis and hematological disorders
Keywords: مبدل سیگنال و فعال کننده رونویسی; 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5â²-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;
The role of T cells in the pathogenesis of Parkinson's disease
Keywords: مبدل سیگنال و فعال کننده رونویسی; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APC; antigen-presenting cell; AQP4; Aquaporin-4; BBB; blood-brain barrier; BCL6; B cell lymphoma 6; BCR; B cell receptor; BEC; brain endothelial cells; CCL20; C-C motif ligand 20; CCR2; C-C
The JAK/STAT signaling pathway and photobiomodulation in chronic wound healing
Keywords: مبدل سیگنال و فعال کننده رونویسی; AP; activator protein; ATP; adenosine triphosphate; Ca2+; calcium ions; cAMP; cyclic adenosine monophosphate; Cox; cytochrome c oxidase; Cu; copper; Cyto c; cytochrome c; DNA; deoxyribonucleic acid; ECM; extracellular matrix; EGF; epidermal growth factor;
Tofacitinib ameliorates inflammation in a rat model of airway neutrophilia induced by inhaled LPS
Keywords: مبدل سیگنال و فعال کننده رونویسی; JAK; Inhaled LPS rat model; Tofacitinib; Lung inflammation; BALF; STAT3; BALF; bronchoalveolar lavage fluid; JAK; janus kinase; LPS; lipopolysaccharide; pSTAT3; phosphorylated STAT3; STAT; signal transducers and activators of transcription; TLR; toll-like
Mitogen-activated protein kinase phosphatase 1 (MKP-1) in macrophage biology and cardiovascular disease. A redox-regulated master controller of monocyte function and macrophage phenotype
Keywords: مبدل سیگنال و فعال کننده رونویسی; ANP; Atrial natriuretic peptide; ARE; AU-rich elements; CS; catalytic sequence; DUSP; dual-specificity phosphatases; ERK; extracellular signal-regulated kinase; Grx; glutaredoxin; HA; hyaluronic acid; IFN; Interferon; IL; Interleukin; JNK; c-Jun N-termina
Fluoro and pentafluorothio analogs of the antitumoral curcuminoid EF24 with superior antiangiogenic and vascular-disruptive effects
Keywords: مبدل سیگنال و فعال کننده رونویسی; CA/VM; chorioallantoic/vitelline membrane; COX; cyclooxygenase; DMEM; Dulbecco's modified Eagle medium; dpf; days past fertilization; FBS; fetal bovine serum; hpa; hours past application; hpf; hours past fertilization; HRP; horseradish peroxidase; mAb;
Attenuated in vitro effects of IFN-α, IL-2 and IL-12 on functional and receptor characteristics of peripheral blood lymphocytes in metastatic melanoma patients
Keywords: مبدل سیگنال و فعال کننده رونویسی; NK; natural Killer; CTL; cytotoxic T lymphocytes; MM; metastatic melanoma; NKG2D; natural killer group 2 D; NCR; natural cytotoxicity receptor; KIR; killer cell immunoglobulin-like receptor; HLA; human leukocyte antigen; MICA/B; MHC-class-I-polypeptide-re
Prostacyclin mimetics afford protection against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice
Keywords: مبدل سیگنال و فعال کننده رونویسی; Acute liver failure; Hepatoprotection; IP receptor; Reactive oxygen species; Signal transducers and activators of transcription; ALF; acute liver failure; ALT; alanine aminotransferase; ANOVA; analysis of variance; AST; aspartate aminotransferase; c-Met;
Trisubstituted purine inhibitors of PDGFRα and their antileukemic activity in the human eosinophilic cell line EOL-1
Keywords: مبدل سیگنال و فعال کننده رونویسی; PDGFRα; platelet derived growth factor receptor alpha; CDK2; cyclin-dependent kinase 2; TK; tyrosine kinase; MAPK; mitogen-activated protein kinase; STAT; signal transducers and activators of transcription;
Original ArticleMACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers
Keywords: مبدل سیگنال و فعال کننده رونویسی; Solid cancers; MACC1; STAT signaling; Fas mediated apoptosis; Bcl-2 family proteins; MACC1; Metastasis associated in colon cancer 1; CRC; Colorectal cancer; STAT; Signal transducers and activators of transcription; JAK; Janus kinase; Mcl-1; Myeloid cell l
The 20Â kDa and 22Â kDa forms of human growth hormone (hGH) exhibit different intracellular signalling profiles and properties
Keywords: مبدل سیگنال و فعال کننده رونویسی; 22K-GH; 22Â kDa growth hormone; 20K-GH; 20Â kDa growth hormone; GHR; growth hormone receptor; JAK; Janus kinase; STAT; signal transducers and activators of transcription; 22Â kDa GH; 20Â kDa GH; Signalling pathway; JAK2-STAT5;
Three STATs are involved in the regulation of the expression of antimicrobial peptides in the triangle sail mussel, Hyriopsis cumingii
Keywords: مبدل سیگنال و فعال کننده رونویسی; Hyriopsis cumingii; Signal transducers and activators of transcription; Innate immunity; Antimicrobial peptides;
Proteome profiling reveals immune responses in Japanese flounder (Paralichthys olivaceus) infected with Edwardsiella tarda by iTRAQ analysis
Keywords: مبدل سیگنال و فعال کننده رونویسی; Japanese flounder; Liver; Differential proteome; Edwardsiella tarda; iTRAQ; C3â¼9; complement component 3-9; p21Ras; GTP-binding protein p21ras; Rab-31-like; Ras-related protein-31-like; NF-κB; nuclear factor-κB; STAT3; signal transducers and activat
RhoA/ROCK pathway mediates leptin-induced uPA expression to promote cell invasion in ovarian cancer cells
Keywords: مبدل سیگنال و فعال کننده رونویسی; uPA; urokinase plasminogen activator; ObR; leptin receptor; OB-Rb; The long form of leptin receptor; RhoA; Ras homolog gene family, member A; ROCK; Rho-associated coiled-coil-forming protein kinase; siRNA; small interfering RNA; C3; C3 transferase; JAK; J
Leflunomide prevents ROS-induced systemic fibrosis in mice
Keywords: مبدل سیگنال و فعال کننده رونویسی; Ab; Antibody; AOPP; Advanced oxidation protein products; AU; Arbitrary Unit; mAb; monoclonal Antibody; DHODH; dihydro-orotate dehydrogenase; ECM; Extracellular matrix; FCS; Fetal calf serum; HOCl; Hypochlorous acid; KLF; Krüppfel-like Factor; PBS; Phosph
Anti-inflammatory effect of Cortex Eucommiae via modulation of the toll-like receptor 4 pathway in lipopolysaccharide-stimulated RAW 264.7 macrophages
Keywords: مبدل سیگنال و فعال کننده رونویسی; CE; Cortex Eucommiae; LPS; lipopolysaccharide; HPLC; high-performance liquid chromatography; RT-PCR; reverse transcriptase-polymerase chain reaction; IC50; inhibitory concentration of 50%; TLR-4; toll-like receptor 4; Myd88; myeloid differentiation primar
Altered expression of interferon-stimulated genes is strongly associated with therapeutic outcomes in hepatitis B virus infection
Keywords: مبدل سیگنال و فعال کننده رونویسی; Chronic hepatitis B; Antiviral therapy; IFN signaling pathway; STAT1; MX; Peg-IFN; pegylated interferon; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; NAs; nucleot(s)ide analogues; CHB; chronic hepatitis B; ETV; entecavir; ISGs; interf
Redox regulation of cardiovascular inflammation - Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species
Keywords: مبدل سیگنال و فعال کننده رونویسی; AP-1; activator protein-1; AT1R; angiotensin II receptor type 1; AT-II; angiotensin II; bFGF; basic fibroblast growth factor; CCR; C-C chemokine receptor; cGMP; cyclic guanosine monophosphate; DC; dendritic cell; eNOS; endothelial nitric oxide synthase;
Nrf2 signaling pathway: Pivotal roles in inflammation
Keywords: مبدل سیگنال و فعال کننده رونویسی; ARE; antioxidant response element; CBP; cAMP-response-element-binding protein binding protein; COX-2; cyclooxygenase 2; Gclc; glutamate cysteine ligase catalytic subunit; Gclm; glutamate cysteine ligase regulatory subunit; GSH; glutathione; HO-1; heme oxy
Redox signaling in the gastrointestinal tract
Keywords: مبدل سیگنال و فعال کننده رونویسی; HNE; 4-hydroxynonenal; 8-OHdG; 8-oxo-7,8-dihydro-2â²-deoxyguanosine; AP-1; Activator protein 1; APC; Adenomatous polyposis coli; APE-1; Apurinic/apyrimidinic endonuclease 1; Math1; Atonal homolog 1; Bax; BCL2-associated X protein; β-TrCP; Beta-transduci
Invited reviewPersonalizing cardiac regenerative therapy: At the heart of Pim1 kinase
Keywords: مبدل سیگنال و فعال کننده رونویسی; MI; myocardial infarction; CPC; cardiac progenitor cell; NFκB; nuclear factor kappa-light-chain-enhancer of activated B cells; STAT; signal transducers and activators of transcription; PI3K; phosphatidylinositide 3-kinases; Klf5; kruppel-like factor 5; E
Ensemble docking-based virtual screening yields novel spirocyclic JAK1 inhibitors
Keywords: مبدل سیگنال و فعال کننده رونویسی; AUC; area under the (ROC) curve; EF; enrichment factor; FDA; Food and Drug Administration; FPR; false positive rate; HTVS; high throughput virtual screening; JAK; Janus kinase; LLE; lipophilic ligand efficiency; LELP; lipophilicity-corrected ligand effici
N-Myc-interacting protein (NMI) negatively regulates epithelial-mesenchymal transition by inhibiting the acetylation of NF-κB/p65
Keywords: مبدل سیگنال و فعال کننده رونویسی; BRCA1; breast cancer 1; CBP; CREB-binding protein; EMT; epithelial-mesenchymal transition; HAT; histone acetyltransferase; HDAC; histone deacetylase; IFN; interferon; IKK; I-κB kinase; KAP1; Krüppel-associated box-associated protein; IRF; IFN regulatory
Aryl Hydrocarbon Receptor Ligands in Cigarette Smoke Induce Production of Interleukin-22 to Promote Pancreatic Fibrosis in Models of Chronic Pancreatitis
Keywords: مبدل سیگنال و فعال کننده رونویسی; TCDD; BaP; Immune Regulation; PSC; CP; AhR; aryl hydrocarbon receptor; αSMA; αâsmooth muscle actin; BaP; benzo[a]pyrene; BM; bone marrow; CP; chronic pancreatitis; ECM; extracellular matrix; IL; interleukin; LPS; lipopolysaccharide; PSC; pancreatic st
The non-pathogenic Henipavirus Cedar paramyxovirus phosphoprotein has a compromised ability to target STAT1 and STAT2
Keywords: مبدل سیگنال و فعال کننده رونویسی; Henipavirus; Cedar virus; Hendra virus; Innate immunity; Interferon; Signal transducers and activators of transcription; Pathogenesis;
Fluoxetine and S-citalopram inhibit M1 activation and promote M2 activation of microglia in vitro
Keywords: مبدل سیگنال و فعال کننده رونویسی; CD86; cluster of differentiation 86; DMEM; Dulbecco' s modified Eagle medium; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; IFN-γ; interferon-γ; IkB-a; inhibitory subunit of NF-kB; IL-6; interleukin-6; LPS; lipopolysaccharide; MTT
Ciliary neurotrophic factor (CNTF): New facets of an old molecule for treating neurodegenerative and metabolic syndrome pathologies
Keywords: مبدل سیگنال و فعال کننده رونویسی; CNTF; ciliary neurotrophic factor; CNTFR; ciliary neurotrophic factor receptor; LIFR; leukemia inhibitor factor receptor; gp130; glycoprotein-130; IL6; Interleukin-6; IFNγ; interferon gamma; JAK; Janus kinases; STAT; signal transducers and activators of
The plastic response of Manduca sexta to host and non-host plants
Keywords: مبدل سیگنال و فعال کننده رونویسی; Manduca sexta; Herbivore; Transcriptome; Detoxification; Olfactory receptor; Immunity; AM; antennae and maxillae; G; gut with Malpighian tubules; SG; silk gland (labial gland); W; whole insect; P450; cytochrome P450 monooxygenase; GST; glutathione S-trans
Cardioprotective potential of annexin-A1 mimetics in myocardial infarction
Keywords: مبدل سیگنال و فعال کننده رونویسی; Ac2-26; Cardioprotection; Cardiomyopathy; Formyl peptide receptors; Inflammation; Ischemia-reperfusion; Aβ42; 42-amino acid beta-amyloid peptide; ABC; ATP-binding cassette; Ac2-26; N-terminal-derived annexin-A1 peptide (acetyl-AMVSEFLKQAWIENEEQEYVVQTVK
Protective effects of the melanocortin analog NDP-α-MSH in rats undergoing cardiac arrest
Keywords: مبدل سیگنال و فعال کننده رونویسی; ACTH-(1-24); adrenocorticotropic hormone (1-24); CA; Cardiac arrest; CPR; cardiopulmonary resuscitation; ECG; electrocardiogram; ERK; extracellular signal-regulated kinases; HCO3â; bicarbonate; HR; heart rate; Htc; hematocrit; IL-6; interleukin-6; IL-10
Determination of the novel genetic variants of goat STAT5A gene and their effects on body measurement traits in two Chinese native breeds
Keywords: مبدل سیگنال و فعال کننده رونویسی; STATs; signal transducers and activators of transcription; JAKs; Janus kinase; JAK-STAT; Janus kinase-signal transducers and activators of transcription pathway; STAT5A; signal transducer and activator of transcription 5A; MGF; mammary gland factor; STAT5
Injury-induced immune responses in Hydra
Keywords: مبدل سیگنال و فعال کننده رونویسی; AMPs; antimicrobial peptides; AP1; activator protein-1; ank; ankyrin repeat; BIR; baculovirus inhibitor of apoptosis protein repeat; CARD; caspase recruitment domain; CC; coiled coil domain; CBP; CREB binding protein; CREB; cAMP response element binding p
Cyclophilin Inhibitors Reduce Phosphorylation of RNA-Dependent Protein Kinase to Restore Expression of IFN-Stimulated Genes in HCV-Infected Cells
Keywords: مبدل سیگنال و فعال کننده رونویسی; Signal Transduction; Cyclosporin; Innate Immunity; Replication; CsA; cyclosporin A; CyP; cyclophilin; HCV; hepatitis C virus; IFN; interferon; IL; interleukin; ISG; IFN-stimulated gene; mRNA; messenger RNA; PKR; double-strand RNA-dependent protein kinase;
T cell regulation in microgravity - The current knowledge from in vitro experiments conducted in space, parabolic flights and ground-based facilities
Keywords: مبدل سیگنال و فعال کننده رونویسی; 5-LOX; 5-lipoxygenase; AP-1; activator protein 1; APO; apoptosis antigen; BL; baseline; ConA; Concanavalin A; CREB; cAMP response element-binding protein; DLR; Deutsches Zentrums für Luft- und Raumfahrt, engl. German Aerospace Center; ESA; European Space