Keywords: مهار کننده های کوچک مولکولی; Functional screening; Small-molecule inhibitors; Personalized medicine; Precision medicine; Functional genomics; Chronic neutrophilic leukemia; Atypical CML;
مقالات ISI مهار کننده های کوچک مولکولی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: مهار کننده های کوچک مولکولی; Small-molecule inhibitors; Autoimmune arthritis; Janus kinases; P38; Spleen tyrosine kinase; Phosphodiesterase 4;
Keywords: مهار کننده های کوچک مولکولی; Sphingomyelin synthase; Small-molecule inhibitors; Structure-based virtual screening; AtherosclerosisSMS, Sphingomyelin synthase; SM, Sphingomyelin; D609, potassium tricyclo[5.2.1.0(2,6)]-decan-8-yl dithiocarbonate; 3D-hSMS1, three-dimensional structure o
ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Cell surface receptors and associated signaling pathways)
Keywords: مهار کننده های کوچک مولکولی; Aflibercept; Bevacizumab; Cetuximab; Infection; Pertuzumab; Small-molecule inhibitors; Trastuzumab; Tyrosine kinase inhibitors; VEGF-targeted agents;
PD-1/PD-L1 inhibitor screening of caffeoylquinic acid compounds using surface plasmon resonance spectroscopy
Keywords: مهار کننده های کوچک مولکولی; PD-1; PD-L1; Surface plasmon resonance; Caffeoylquinic acid compounds; Small-molecule inhibitors;
ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Intracellular signaling pathways: tyrosine kinase and mTOR inhibitors)
Keywords: مهار کننده های کوچک مولکولی; BCR-ABL kinase inhibitors; Ibrutinib; Idelalisib; Infection; Janus kinase inhibitors; mTOR inhibitors; Small-molecule inhibitors;
ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Introduction)
Keywords: مهار کننده های کوچک مولکولی; Biological therapies; Infection; Monoclonal antibodies; Recommendations; Review; Small-molecule inhibitors; Targeted therapies;
Discovery of new MurA inhibitors using induced-fit simulation and docking
Keywords: مهار کننده های کوچک مولکولی; MurA inhibitors; ProBiS-CHARMMing web server; Induced fit; Small-molecule inhibitors; Antibacterial agents;
Aryl amide small-molecule inhibitors of microRNA miR-21 function
Keywords: مهار کننده های کوچک مولکولی; miR-21; MicroRNA; Small-molecule inhibitors; Cancer; Gene regulation; Post-transcriptional regulation;
Structure-based design of conformationally constrained cyclic peptidomimetics to target the MLL1-WDR5 protein–protein interaction as inhibitors of the MLL1 methyltransferase activity
Keywords: مهار کننده های کوچک مولکولی; Epigenetics; MLL1 histone methyltransferase; WDR5-MLL1 interaction; Small-molecule inhibitors; Cyclic peptidomemtics
The phospholipase D superfamily as therapeutic targets
Keywords: مهار کننده های کوچک مولکولی; PLD1; PLD2; small-molecule inhibitors; cancer; thrombosis; autoimmune disease
Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma
Keywords: مهار کننده های کوچک مولکولی; Exportin-1; CRM1; XPO1; Small-molecule inhibitors; HIV; AIDS-related lymphoma; Primary effusion lymphoma
An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies
Keywords: مهار کننده های کوچک مولکولی; HMGB1; HMGB1-receptors; Small-molecule inhibitors; Peptide/protein inhibitors; DNA-based inhibitorsEP, ethyl pyruvate; GL, glycyrrhizin; HMGB, High-Mobility Group Box; IL, interleukin; I/R, ischemia–reperfusion; LPS, lipopolysaccharide; ODN, oligodeoxyrib
A review of non-nucleoside anti-hepatitis B virus agents
Keywords: مهار کننده های کوچک مولکولی; Hepatitis B virus; Inhibitor; Non-nucleoside; Small-molecule inhibitors; Natural products; Synthetic compounds
Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2-p53 interaction
Keywords: مهار کننده های کوچک مولکولی; Small-molecule inhibitors; MDM2-p53 interaction; Antiproliferative activity;
Identification and characterization of small molecule inhibitors of signal transducer and activator of transcription 3 (STAT3) signaling pathway by virtual screening
Keywords: مهار کننده های کوچک مولکولی; STAT3 signaling; Small-molecule inhibitors; Virtual screening; Cell viability; Antitumor activity;
New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia
Keywords: مهار کننده های کوچک مولکولی; UPR; Hypoxia; Small-molecule inhibitors; PERK; IRE1α;
Small-molecule inhibitors of cathepsin L incorporating functionalized ring-fused molecular frameworks
Keywords: مهار کننده های کوچک مولکولی; Small-molecule inhibitors; Cathepsin L; Chemical synthesis; Enzyme inhibition;
Discovery of novel inhibitors of signal transducer and activator of transcription 3 (STAT3) signaling pathway by virtual screening
Keywords: مهار کننده های کوچک مولکولی; STAT3 signaling; Small-molecule inhibitors; Virtual screening; Cell viability; Antitumor activity
Relapses, treatments and new drugs
Keywords: مهار کننده های کوچک مولکولی; diffuse large B-cell lymphoma; salvage chemotherapy; monoclonal antibody; small-molecule inhibitors
Identification of 2,3,6-trisubstituted quinoxaline derivatives as a Wnt2/β-catenin pathway inhibitor in non-small-cell lung cancer cell lines
Keywords: مهار کننده های کوچک مولکولی; Wnt protein; Small-molecule inhibitors; Anticancer agents; Drug-like library
12 Arylstibonic acids that inhibit the DNA binding of five B-ZIP dimers
Keywords: مهار کننده های کوچک مولکولی; Arylstibonic acids; DNA binding; B-ZIP domain; Leucine zipper; Antimony; Small-molecule inhibitors;
A Multitude of Kinases-Which are the Best Targets in Treating Rheumatoid Arthritis?
Keywords: مهار کننده های کوچک مولکولی; MAPKs; Tyrosine kinases; IKK; Jak; Syk; Small-molecule inhibitors;
Hedgehog beyond medulloblastoma and basal cell carcinoma
Keywords: مهار کننده های کوچک مولکولی; Hedgehog pathway; Medulloblastoma; Basal cell carcinoma; Pancreatic cancer; Mouse cancer models; Small-molecule inhibitors
Design, synthesis, and evaluation of peptidomimetics containing Freidinger lactams as STAT3 inhibitors
Keywords: مهار کننده های کوچک مولکولی; STAT3; Small-molecule inhibitors; Peptidomimetics; Freidinger lactams
Design, synthesis, and characterization of new embelin derivatives as potent inhibitors of X-linked inhibitor of apoptosis protein
Keywords: مهار کننده های کوچک مولکولی; XIAP; Embelin; Small-molecule inhibitors
The molecular pathology of new anti-cancer agents
Keywords: مهار کننده های کوچک مولکولی; Cancer; Drugs; Monoclonal antibodies; Small-molecule inhibitors; Growth factor receptors; Cetuximab; Trastuzumab; Bevacizumab; Imatinib mesylate; Gefitinib; Histopathology testing; Personalized medicine;