Keywords: Silanol; Sila-substitution; Nuclear receptor; Pregnane X receptor (PXR); Retinoic acid receptor-related orphan receptor (ROR); T0901317
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Activation of liver X receptors inhibit LPS-induced inflammatory response in primary bovine mammary epithelial cells
Keywords: Liver X receptors; T0901317; TLR4; Lipid raft; Cytokines; NF-κB;
LXR activation increases the expression of GnRH AND αMSH in the rat hypothalamus in vivo
Keywords: T0901317; GW3965; GHRH; NPY; ABCA1; GLUT2;
Development of novel silanol-based human pregnane X receptor (PXR) agonists with improved receptor selectivity
Keywords: Pregnane X receptor; Nuclear receptor; Silanol; Sila-substitution; C/Si-exchange; Alcohol/silanol-exchange; T0901317;
Liver X receptors agonists suppress NLRP3 inflammasome activation
Keywords: LXRs; liver X receptors; LXRα; NR1H3; LXRβ; NR1H2; T0901317; T09; GW3965; GW; mtROS; mitochondria reactive oxygen species; NLRP3; the NLR family pyrin domain-containing protein 3; ASC; speck-like protein containing a caspase recruitment domain; PAMP; pa
Functional induction of P-glycoprotein efflux pump by phenyl benzenesulfonamides: Synthesis and biological evaluation of T0901317 analogs
Keywords: T0901317; Benzene sulfonamides; PXR; LS180; P-gp induction; Alzheimer’s disease
The influence of ligand-activated LXR on primary human trophoblasts
Keywords: LXR; Trophoblast; Oxysterol; T0901317; SREBP2
Neuropharmacology and analgesiaLiver X receptor agonist T0901317 reduces neuropathological changes and improves memory in mouse models of experimental dementia
Keywords: T0901317; Liver X receptors; Streptozotocin; High fat diet; Dementia;
LXR-α antagonist meso-dihydroguaiaretic acid attenuates high-fat diet-induced nonalcoholic fatty liver
Keywords: ABCA1, ABCG1; ATP-binding cassette transporter A1 or G1; AMPK; AMP-activated protein kinase; ACC; acetyl-coenzyme A carboxylase; FAS; fatty acid synthase; HDL; high density lipoprotein; HFD; high fat diet; LBD; ligand binding domain; LXR; liver X receptor
Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc
Keywords: RORc; RORγ; T0901317; X-ray structure; IL-17; Inflammation; Autoimmune;
Elimination of macrophages drives LXR-induced regression both in initial and advanced stages of atherosclerotic lesion development
Keywords: Atherosclerosis; Regression; Bone marrow transplantation; Liver X receptor; T0901317
Liver X receptor agonist T0901317 induced liver perturbation in zebrafish: Histological, gene set enrichment and expression analyses
Keywords: Zebrafish; Liver X receptor; T0901317; Liver; Toxicogenomics; Transcriptome
Liver X receptor activation restores memory in aged AD mice without reducing amyloid
Keywords: LXR; Alzheimer's disease; Cholesterol; T0901317; Amyloid; Apoe; Abca1; Abcg1
T0901317, an LXR agonist, augments PKA-induced vascular cell calcification
Keywords: T0901317; Liver X receptor; Calcification; Smooth muscle cell
PPARα gene expression is up-regulated by LXR and PXR activators in the small intestine
Keywords: GW3965; LXR; PCN; PPARα; PXR; T0901317; Transcriptional regulation; Lipid metabolism
Liver X receptor agonist downregulates hepatic apoM expression in vivo and in vitro
Keywords: Apolipoprotein M; Liver X receptor; T0901317; 9-Cis retinoic acid
Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists
Keywords: Liver X receptor agonists; Pregnane X receptor; T0901317; CYP3A4; CYP2B6; Human hepatocytes
The liver X receptor agonist T0901317 acts as androgen receptor antagonist in human prostate cancer cells
Keywords: T0901317; Antiandrogen; Androgen; AR; LNCaP; PSA; LXR agonist
Discovery and optimization of a novel series of liver X receptor-α agonists
Keywords: Hexafluorocarbinol; Liver X receptor-α; LXRα agonist; T0901317; Cholesterol transporter
Evidence for an indirect transcriptional regulation of glucose-6-phosphatase gene expression by liver X receptors
Keywords: Glucose-6-phosphatase; Insulin; Diabetes; Gluconeogenesis; LXR; Liver; T0901317;