دانلود مقالات ISI درباره Tcga + ترجمه فارسی

Large-scale evaluation of SLC18A2 in prostate cancer reveals diagnostic and prognostic biomarker potential at three molecular levels

Keywords: Prostate cancer; SLC18A2; Diagnosis; Prognosis; Biomarkers; AN; Adjacent normal; BPH; Benign prostatic hyperplasia; CRPC; Castration-resistant prostate cancer; PIN; Prostate intraepithelial neoplasia; MPC; Metastatic prostate cancer; RP; Radical prostatec

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal

Keywords: Ovarian cancer; DBeQ; ML240; Salubrinal; ER stress; Unfolded protein response; CB-5083; Synergy; AAA-ATPase; ATPase associated with diverse cellular activities; BRCA1/2; breast cancer 1/2; PARP1; poly ADP-ribose polymerase-1; DBeQ; N2,N4-dibenzylquinazoli

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

L1CAM is an independent predictor of poor survival in endometrial cancer - An analysis of The Cancer Genome Atlas (TCGA)

Keywords: L1CAM; Endometrial cancer; TCGA;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Single cell genomics reveals activation signatures of endogenous SCAR's networks in aneuploid human embryos and clinically intractable malignant tumors

Keywords: Human endogenous stem cell-associated retroviruses (SCARs); Human-specific regulatory sequences; Human embryos; LTR7/HERVH; Therapy-resistant cancers; Cancer stem cells; HERV; human endogenous retroviruses; hESC; human embryonic stem cells; LINE; long int

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

The impact of next-generation sequencing on the DNA methylation-based translational cancer research

Keywords: BS; bisulfite sequencing; DMR; differentially methylated region; HGOSC; high-grade ovarian serous carcinoma; MBD; methyl-binding domain; 5-mC; 5-methylcytosine; MeCP2; methyl CpG binding protein 2; NGS; next-generation sequencing; NSCLC; non-small cell lu

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer

Keywords: Transcriptome; Editome; RNA Editing; ADARs; ADAR; adenosine deaminase that act on RNA; A-to-G; adenosine to guanosine; A-to-I; adenosine to inosine; CDS; coding sequences; CM; catalytic mutant; DR; down-regulation; edt; edited; EV; empty vector; GC; gastr

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma

Keywords: Sleeping Beauty; Liver Cancer; RalGAPs; Kinase Inhibitor; CCG; candidate cancer genes; CIS; common transposon insertion site; gCIS; gene-centric common transposon insertion site-calling method; GTPase; guanosine triphosphatase; HBsAg; hepatitis B surfac

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Phosphoproteomic Analyses of NRAS(G12) and NRAS(Q61) Mutant Melanocytes Reveal Increased CK2α Kinase Levels in NRAS(Q61) Mutant Cells

Keywords: a-loop; activation loop; ERK; extracellular signal-regulated kinase; GO; gene ontology; GTP; guanosine triphosphate; MAPK; mitogen-activated protein kinase; MEK; MAPK/ERK kinase; NRAS; neuroblastoma rat sarcoma viral homolog; PHM; primary human melanocyte

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Overexpression of stathmin/oncoprotein 18 correlates with poorer prognosis and interacts with p53 in oral squamous cell carcinoma

Keywords: Stathmin; Oral squamous cell carcinoma; Biomarker; TP53; TCGA; Prognosis;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Identification, Review, and Systematic Cross-Validation of microRNA Prognostic Signatures in Metastatic Melanoma

Keywords: AJCC; American Joint Committee on Cancer; LOOCV; leave-one-out cross-validation; miRNA; microRNA; TCGA; The Cancer Genome Atlas;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Original ResearchBrief ReportGermline Mutations in FAN1 Cause Hereditary Colorectal Cancer by Impairing DNA Repair

Keywords: Lynch Syndrome; Genetic Risk Factor; Susceptibility; DNA Mismatch Repair; CRC; colorectal cancer; FA; Fanconi anemia; MMC; mitomycin C; MMR; DNA mismatch repair; TCGA; The Cancer Genome Atlas;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Application of the rank-based method to DNA methylation for cancer diagnosis

Keywords: SVM; support vector machine; KNN; k-nearest neighbor; TSP; Top scoring pair; R-pairs; the relative methylation level reversal pairs; FR-pairs; the relative methylation level reversal pairs with frequency; GEO; Gene Expression Omnibus; TCGA; The Cancer Gen

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Comprehensive expression analysis of miRNA in breast cancer at the miRNA and isomiR levels

Keywords: BC; breast cancer; KEGG; Kyoto Encyclopedia of Genes and Genomes; GO; gene ontology; BRCA; breast cancer tissue; BRCA-NT; breast cancer-normal tissue; TCGA; The Cancer Genome Atlas; Breast cancer (BC); MicroRNA (miRNA); IsomiR; Expression;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

The S100P/RAGE signaling pathway regulates expression of microRNA-21 in colon cancer cells

Keywords: Colon cancer; Metastasis; Inflammation; microRNAs; miR-21; RAGE; RECK; AP-1; TCGA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Expression of lactate/H+ symporters MCT1 and MCT4 and their chaperone CD147 predicts tumor progression in clear cell renal cell carcinoma: immunohistochemical and The Cancer Genome Atlas data analyses

Keywords: Renal cell carcinoma; Monocarboxylate; CD147; Aerobic glycolysis; TCGA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Optimal design of trials to demonstrate the utility of genomically-guided therapy: Putting Precision Cancer Medicine to the test

Keywords: Clinical trial design; Precision Cancer Medicine; Targeted therapy; CSC; Cancer stem cell; COSMIC; Catalogue of Somatic Mutations in Cancer; CTC; Circulating tumor cell; ctDNA; Circulating tumor DNA; CRC; Colorectal cancer; DCR; Disease control rate; EMA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature

Keywords: Glioblastoma; Prognosis; MicroRNA; Signature; TCGA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling

Keywords: APC; adenomatous polyposis coli; BAC; bacterial artificial chromosome; CBC; crypt base columnar; Cp; crossing point; CRC; colorectal carcinoma; CTNNB1; the β-CATENIN gene; Dvl; dishevelled; EGFP; enhanced green fluorescent protein; EphB2; ephrin type-B r

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer

Keywords: NF-κB signaling; Breast cancer; MicroRNA; Cell cycle progression; CSF2; colony stimulating factor 2; CCNE1; cyclin E1; CCND1; cyclin D1; CDK; cyclin-dependent kinase; CTRL; control; CXCL; chemokine (C-X-C motif) ligand; ER; estrogen receptor; I.B; intens

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

The histone chaperone HJURP is a new independent prognostic marker for luminal A breast carcinoma

Keywords: Chromatin; Epigenetics; Biomarkers; Prognosis; MKI67; CENP-A; AFA; Adaptive Focused Acoustics; ASF1; anti-silencing function 1; BCSS; breast cancer specific survival; BLC; basal-like cancer; CAF-1; chromatin assembly factor 1; CENP-A; centromere protein A

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

SOX15 Governs Transcription in Human Stratified Epithelia and a Subset of Esophageal Adenocarcinomas

Keywords: Barrett's Esophagus; Esophageal Gene Regulation; Esophageal Transcriptome; SOX15 Cistrome; BE; Barrett's esophagus; CDX1/2; caudal type homeobox 1/2; ChIP; chromatin immunoprecipitation; ChIP-seq; chromatin immunoprecipitation with high-throughput seq

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

The role of Myc and let-7a in glioblastoma, glucose metabolism and response to therapy

Keywords: GBM; glioblastoma multiforme; let-7a; lethal-7a; miRNA; microRNA; TCGA; The Cancer Genome Atlas; GLUT; glucose transporter; PKM2; pyruvate kinase M2; PDK; pyruvate dehydrogenase kinase; MGMT; O6-methylguanine-DNA methyltransferase; GSK3β; glycogen syntha

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of reference miRNAs in human tumors by TCGA miRNA-seq data

Keywords: Reference miRNA; miRNA-seq; TCGA

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

ClearCode34: A Prognostic Risk Predictor for Localized Clear Cell Renal Cell Carcinoma

Keywords: Biomarker; ccRCC; Kidney cancer; Renal cell carcinoma; TCGA; Prognosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Big linked cancer data: Integrating linked TCGA and PubMed

Keywords: TCGA; PubMed; RDF; Linked data; Visualization;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Colorectal Carcinomas With CpG Island Methylator Phenotype 1 Frequently Contain Mutations in Chromatin Regulators

Keywords: Colon Cancer; Hypermethylation; Microsatellite Instability; Gene Silencing; CIMP; CpG island methylator phenotype; CRC; colorectal carcinoma; SNP; single-nucleotide polymorphism; TCGA; The Cancer Genome Atlas;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Sox2 Promotes Malignancy in Glioblastoma by Regulating Plasticity and Astrocytic Differentiation

Keywords: α-SMA; actin alpha 2 smooth muscle (ACTA2); CNS; central nervous system; CSC; cancer stem-like cell; DEG; differentially expressed gene; ESC; embryonic stem cell; GFAP; glial fibrillary acidic protein; GBM; glioblastoma; GS; gliosarcoma; IF; intermediate

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

Keywords: PI3K pathway; Targeted therapy; Predictive biomarkers; 4EBP1; 4E-binding protein 1; AKT; protein kinase-B; AMPK; AMP-activated protein kinase; COSMIC; Catalogue of Somatic Mutations in Cancer; eIF4E; eukaryotic initiation factor 4E; ERK; extracellular-sig

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2014 سفارش ترجمه

MENT: Methylation and expression database of normal and tumor tissues

Keywords: MENT; Methylation and Expression database of Normal and Tumor tissues; GEO; Gene Expression Omnibus; TCGA; The Cancer Genome Atlas; DM; differential methylation value; DNA methylation; Cancer; Gene expression;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Multifunctional protein APPL2 contributes to survival of human glioma cells

Keywords: Tumor cell biology; Apoptosis; Gene expression; Endocytosis; APPL proteins; HRK; GBM; glioblastoma; NuRD; nucleosome remodeling and deacetylase; RNAi; RNA interference; RTK; receptor tyrosine kinase; siRNA; small interfering RNA; shRNA; short hairpin RNA;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Validated gene targets associated with curatively treated advanced serous ovarian carcinoma

Keywords: Ovarian cancer; Long-term survivors; Outcome; Gene expression; TCGA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Genetics and pharmacogenomics of diffuse gliomas

Keywords: Companion diagnostics; Glioma; 1p/19q co-deletion; IDH1; Pharmacogenomics; EGFRvIII; CGH; comparative genomic hybridization; CNA; copy number aberrations; CRC; colorectal carcinoma; CML; chronic myeloid leukemia; EGFR; epidermal growth factor receptor; FF

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of candidate SNPs for drug induced toxicity from differentially expressed genes in associated tissues

Keywords: CYP; cytochrome P450; GWAS; genome-wide association studies; GEO; Gene Expression Omnibus; NCI-CTC; National Cancer Institute Common Toxicity Criteria; SMD; Stanford Microarray Database; SNPs; single nucleotide polymorphisms; TCGA; The Cancer Genome Atlas

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

The Transcriptional Consequences of Somatic Amplifications, Deletions, and Rearrangements in a Human Lung Squamous Cell Carcinoma

Keywords: lincRNA; long intergenic non-coding RNA; miRNA; microRNA; ncRNA; non-coding RNA; PI3K; phosphatidylinositol 3-kinase; SCC; squamous cell carcinoma; snoRNA; small nucleolar RNA, RNA; TCGA; The Cancer Genome Atlas;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Exome Array Analysis Identifies Variants in SPOCD1 and BTN3A2 That Affect Risk for Gastric Cancer

Keywords: Stomach Cancer; Genetics; Mutation; Gene Regulation; BTN; butyrophilin; ENCODE; Encyclopedia of DNA Elements; GTEx; genotype-tissue expression; GWAS; genome-wide association studies; GWAS-BJ; the Beijing samples of our previous GWAS; GWAS-NCI; gastric can

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2011 سفارش ترجمه

Exposing the cancer genome atlas as a SPARQL endpoint

Keywords: TCGA; SPARQL; RDF; Linked Data; Data integration

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه