Keywords: BoNT; botulinum neurotoxins; TeNT; tetanus toxin; LC; light chain of botulinum neurotoxins; HC; heavy chain of botulinum neurotoxins; HCN; translocation domain of botulinum neurotoxins; HCC; receptor binding domains of botulinum neurotoxins; LD50; half-le
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Keywords: Botulinum toxins; Clinical trial; AE; Adverse event; BoNT; Botulinum neurotoxin; CD; Cervical dystonia; CGRP; calcitonin gene-related peptide; CP; cerebral palsy; IGA; Investigator's Global Assessment; IL-6; Interleukin 6; MMP-1; Matrix metalloproteinase-
Keywords: AZ; active zone; BoNT; botulinum neurotoxin; CAZ; cytomatrix at the active zone; GFAP; glial fibrillary acidic protein; Munc; mammalian uncoordinated; Nrxn1; Neurexin 1-alpha; RABV; rabies virus; RIM; regulating synaptic membrane exocytosis protein; RIM-B
Keywords: 3-ADON; 3-acetyldeoxynivalenol; 15-ADON; 15-acetyldeoxynivalenol; AME; alternariol methyl ether; AOH; alternariol; ANOVA; analysis of variance; AUR; aurofusarin; BEA; beauvericin; BIK; bikaverin; BUT; butenolide; CHRY; chrysogine; CULM; culmorin; DEC; dec
Keywords: BoNT; botulinum neurotoxin; CT; cholera toxin; PAMPs; pathogen-associated molecular patterns; ENS; enteric nervous system; PSA; polysaccharide A; SCFAs; short-chain fatty acids; CNS; central nervous system; GABA; γ-aminobutyric acid; TeNT; tetanus neurot
In vitro potency determination of botulinum neurotoxin serotype A based on its receptor-binding and proteolytic characteristics
Keywords: Botulinum neurotoxin serotype A (BoNT/A); In vitro assay; Binding and cleavage assay (BINACLE assay); Activity determination; BINACLE; Binding and cleavage assay; BoNT; Botulinum neurotoxin; BSA; Bovine serum albumin; GT1b; Trisialoganglioside GT1b; H-cha
The in vitro detection of botulinum neurotoxin-cleaved endogenous VAMP is epitope-dependent
Keywords: AraC; cytosine β-d-arabinofuranoside; BoNT; botulinum neurotoxin; DIV; days in vitro; ELISA; enzyme-linked immunosorbent assay; FBS; foetal bovine serum; HBSS; Hank's Balanced Salt Solution; PBS; phosphate buffered saline; PLO; poly-l-ornithine; RabMAb;
Botulinum neurotoxin type A-cleaved SNAP25 is confined to primary motor neurons and localized on the plasma membrane following intramuscular toxin injection
Keywords: 2D; 2 dimensional; BoNT/A; botulinum neurotoxin type A; ChAT; choline acetyltransferase; CNS; central nervous system; CTB AF-488; cholera toxin B subunit Alexa Fluor 488 conjugate; DAS; digit abduction score; GAD; glutamic acid decarboxylase; GFAP; glial
Submolecular recognition of the C-terminal domain of the heavy chain of botulinum neurotoxin type A by T cells from toxin-treated cervical dystonia patients
Keywords: Ab; antibody; BoNT/A; botulinum neurotoxin type A; BoNT/Ai; inactivated BoNT/A; BoNT/B; botulinum neurotoxin type B; CD; cervical dystonia; L chain; the light chain (residues 1-448) of BoNT/A; HLA; human leukocyte antigen; H chain; the heavy chain (resi
Tent and a subclass of P5-free graphs
Keywords: P5-free graphs; Maximum weight independent set; Homogeneous sets; Prime graphs; Tent
Results of an international transferability study of the BINACLE (binding and cleavage) assay for in vitro detection of tetanus toxicity
Keywords: Tetanus neurotoxin; Toxoid vaccines; In vitro toxicity assay; Transferability study; BINACLE; binding and cleavage; BSA; bovine serum albumin; ELISA; enzyme-linked immunosorbent assay; IVI; Institute of Virology and Immunology; NIBSC; National Institute
Engineering Clostridia Neurotoxins with elevated catalytic activity
Keywords: Botulinum Neurotoxin B; TeNT; Light chain; VAMP2; Engineering; Elevated activity; CNTs; Clostridia Neurotoxins; BoNT/B; Botulinum Neurotoxin; TeNT; Tetanus Neurotoxin; LC; light chain; VAMP2; vesicle associated membrane protein-2; SNARE; soluble NSF attac
Effect of Fuel Type on Carbon Monoxide Accumulation in Tents of Varied Design
Keywords: carbon monoxide; camping stove; tent; stove; backpacking;
Basic NeuroscienceShort communicationAccurate quantification of tetanus neurotoxin-induced focal spasticity in mice using complex running wheels
Keywords: ANOVA; analysis of variance; TeNT; tetanus neurotoxin; Tac; accumulative running time; Vmax; maximum running velocity; VAMP; vesicle associated membrane protein; Tetanus neurotoxin; Mice; Wheel running; In vivo test; Spasticity; Rehabilitation;
Molecular immune recognition of botulinum neurotoxin B. The light chain regions that bind human blocking antibodies from toxin-treated cervical dystonia patients. Antigenic structure of the entire BoNT/B molecule
Keywords: Ab; antibody; BSA; bovine serum albumin; BoNT; botulinum neurotoxin; BoNT/A; botulinum neurotoxin, type A; BoNT/B; botulinum neurotoxin, type B; CD; cervical dystonia; HN; the N-terminal domain of the H chain of the respective toxin (BoNT/B residues 442â
Human T-cell responses to botulinum neurotoxin. Responses in vitro of lymphocytes from patients with cervical dystonia and/or other movement disorders treated with BoNT/A or BoNT/B
Keywords: Ab; antibody; BoNT/A; botulinum neurotoxin type A; BoNT/B; botulinum neurotoxin type B; CD; cervical dystonia; ECD; exclusive CD (i.e., patient diagnosed with CD only); FET; Fisher's exact test; MPA; mouse protection assay; non-CD; other movement disorder
In vitro determination of tetanus toxicity by an endopeptidase assay linked to a ganglioside-binding step
Keywords: Clostridial neurotoxins; Tetanus neurotoxin; In vitro; Endopeptidase assay; Binding assay; Synaptobrevin; Gangliosides; BoNT; botulinum neurotoxin; BSA; bovine serum albumin; EP; European Pharmacopoeia; H-chain; heavy chain; L-chain; light chain; Lf; limi
Medical aspects of toxin weapons
Keywords: BoNT; botulinum neurotoxin; CNT; clostridial neurotoxins; ER; endoplasmic reticulum; HC; heavy chain; HC; 50Â kDa C-terminal half of HC; HN; 50Â kDa N-terminal half of HC; LC; light chain; MLD; median lethal dose; RIP; ribosome inactivating protein; RTA;
Neurotoxicity of nitroxyl: Insights into HNO and NO biochemical imbalance
Keywords: nNOS or NOS-1; neuronal isoform of nitric oxide synthase; NO; nitric oxide; AS; Angeli's salt; FeTPPS; 5,10,15,20-tetrakis (4-sulfonatophenyl) prophyrinato ferric chloride; MK-801; dizocilpine maleate; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; Ara-C; cy
Internalization of a GFP-tetanus toxin C-terminal fragment fusion protein at mature mouse neuromuscular junctions
Keywords: α-BTX; α-bungarotoxin; β-gal; β-galactosidase; β-gal-TTC; fusion protein of β-gal and C-terminal fragment of tetanus toxin; CT-B; AlexaFluor 594-conjugated B-subunit of cholera toxin; GFP; green fluorescent protein; GFP-TTC; fusion protein of GFP an
Changes in secondary glutamate release underlie the developmental regulation of excitotoxic neuronal cell death
Keywords: development; excitotoxicity; NMDA receptor; glutamate release; cortex; cell culture; Ara-C; β-d-arabinofuranoside; CREB; cAMP response element binding protein; CS; calf serum; DIV; day in vitro; FBS; fetal bovine serum; HBSS; HEPES-buffered salt solution