Keywords: AED; antiepileptic drug; AGA; anti-gliadin antibody; EMA; endomysial antibody; HLA; human leukocyte antigen; MRI; magnetic resonance imaging; NAA/Cr; N-acetyl aspartate:creatine ratio; PHT; patients without clinical evidence of ataxia; PHTA; patients with
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Keywords: Biomarker; Kidney; Tubular injury; Urine; AKI; acute kidney injury; CKD; chronic kidney disease; DKD; diabetic kidney disease; eGFR; estimated glomerular filtration rate; ERK; extracellular signal-regulated kinase; ESRD; end-stage renal disease; FcαRI/CD
Keywords: dent; dentin; GTA; glutaraldehyde; HA; hydroxyapatite; LVDT; linear variable differential transformer; NC9; irreversible inhibitor of TG2; OPN; osteopontin; RDCB; rigid double cantilever beam; SIBLING; Small, Integrin-Binding LIgand N-linked Glycoprotein;
Keywords: DIV; days in vitro; ECM; extracellular matrix; MCAL; middle cerebral artery ligation; NES; nuclear export signal; NLS; nuclear localization signal; OGD; oxygen and glucose deprivation; scr; scrambled; TG2; transglutaminase 2; Transglutaminase; Neurons; RN
Keywords: Dopaminergic (DA) neurons; Inflammatory mediators; Mast cells; Parkinson's disease; Substantia nigra; Transglutaminase 2; BMMCs; Bone marrow-derived mast cells; DA neurons; Dopaminergic neurons; DAT; dopamine transporter; LTs; Leukotrienes; MAOB; Monoamin
Keywords: ASO; antisense oligonucleotide; ECM; extracellular matrix; DDR; discoidin domain receptor; FAP; fibroblast activation protein; HSC; hepatic stellate cell(s); MF; myofibroblast(s); Lox; lysyl oxidase; Loxl; lysyl oxidase-like; MMP; matrix metalloproteinase
Keywords: AN; Aspergillus niger; AO; Aspergillus flavus var. oryzae; CD; celiac disease; DPP; dipeptidyl peptidase; EC; Enzyme Commission number; ELISA; enzyme-linked immunosorbent assay; EP-B2; glutamine-specific cysteine endopeptidase B, isoform 2 from barley; FM
Keywords: Tissue transglutaminase; TG2; Fluorine-18; Irreversible TG2 inhibitors; MDA-MB-231;
Keywords: EmA; tTGA; Autoimmunity; Wheat; ACD; active celiac disease; ANA; antinuclear antibody; AU; arbitrary units; CD; celiac disease; EmA; endomysial antibody; GCD; gluten-containing diet; GFD; gluten-free diet; IBS; irritable bowel syndrome; IEL; intraepitheli
Keywords: ALIX; apoptosis-linked gene-2-interacting protein X; BAG3; BCL2-associated athanogene 3; BAP; 5-(biotinamido)pentylamine; ESCRT; endosomal sorting complex required for transport; HEK293; human embryonic kidney cells; MEF; murine embryonic fibroblasts; mHt
Keywords: Coeliac disease; Gluten; Non-coeliac gluten sensitivity; Wheat allergy; ATI; amylase trypsin inhibitor; CD; coeliac disease; CU; contact urticaria; DH; dermatitis herpetiformis; ESPGHAN; European Society for Pediatric Gastroenterology, Hepatology and Nutr
Keywords: Celiac Disease; HLA; T Cell; CD4; Intraepithelial Lymphocyte; Intestinal Epithelial Cell; Immunology; IEC; intestinal epithelial cells; IEL; intraepithelial lymphocytes; IFN; interferon; IL; interleukin; ILC; innate lymphoid cell; MMP; matrix metallopepti
Keywords: Bcl-2; B-cell lymphoma 2; IL-6; interleukin-6; INF-γ; interferon-γ; MGD; Meibomian gland dysfunction; MMP9; matrix metalloproteinase 9; RT PCR; real-time polymerase chain reaction; SS; Sjögren syndrome; TBUT; tear film break-up time; TG2; transglutamin
Keywords: AML; acute myeloid leukemia; APL; acute promyelocytic leukemia; ATRA; all-trans retinoic acid; BHA; butylated hydroxyanisole; C/EBP; CCAAT/enhancer binding proteins; CREB; cyclic AMP response element-binding proteins; CSF; cerebrospinal fluid; DUOX; dual
Keywords: AML; acute myeloid leukemia; CAM-DR; cell adhesion-mediated drug resistance; CCP; charge-conversion polymer; CLL; chronic lymphocytic leukemia; CNS; central nervous system; CSC; cancer stem cell; EGFR; epidermal growth factor receptor; EPR; enhanced perme
15(V/K) kinetic isotope effect and steady-state kinetic analysis for the transglutaminase 2 catalyzed deamidation and transamidation reactions
Keywords: Isotope effects; Polyamidation; Deamidation; Transglutaminase; Steady-state kinetics; KIE; kinetic isotope effect; TG2; transglutaminase 2, tissue transglutaminase; Z-Gln-Gly; N-Benzyloxycarbonyl-l-Glutaminylglycine;
Osteopontin as a novel substrate for the proprotein convertase 5/6 (PCSK5) in bone
Keywords: OPN; osteopontin; FAM20C; family with sequence similarity 20, member C; TNAP; tissue nonspecific alkaline phosphatase; PHEX; phosphate-regulating gene with homologies to endopeptidases on the X chromosome; PC5/6; proprotein convertase 5/6; PC5/6 KO; propr
Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms
Keywords: ABC; ATP-binding cassette; ABCA1; ATP-binding membrane cassette transporter A1; ABCG1; ATP binding cassette transporter G1; ABCA7; ATP-binding cassette transporters A7; Abs; Antibodies; ACs; Apoptotic cells; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ri
HLA-DQ-Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption
Keywords: CD38; Gluten-Sensitive; Gut-Homing; Noninvasive Test; β7; integrin β7; CI; confidence interval; DGP; deamidated gliadin peptide; gluten-specific T cells; HLA-DQ-gluten-tetramer+ integrin β7+ effector-memory T cells; ELISA; enzyme-linked immunosorbent
New insights in the pathogenesis of immunoglobulin A vasculitis (Henoch-Schönlein purpura)
Keywords: ADCC; antibody-dependent cellular cytotoxicity; AECA; Anti-epithelial cell antibodies; ANCA; Anti-neutrophil cytoplasmic antibodies; β2GPI; β2-glycoprotein I; CDC; Complement-dependent cytotoxicity; EC; endothelial cell; FcαRI; Fc receptor for IgA; Gal
A B-Cell Gene Signature Correlates With the Extent of Gluten-Induced Intestinal Injury in Celiac Disease
Keywords: Oral Tolerance; Mucosal Immunity; Autoimmunity; Regulatory B Cell; Cd; crypt depth; CeD; celiac disease; cRNA; complementary RNA; TG2; transglutaminase 2; TR; T-cell receptor; Vh; villus height; Vh:Cd; ratio of villus height to crypt depth;
Similar Responses of Intestinal T Cells From Untreated Children and Adults With Celiac Disease to Deamidated Gluten Epitopes
Keywords: Autoimmunity; CD4+ T Cell; TG2; PreventCD Study; CT-gluten; chymotrypsin digest of gluten; IL; interleukin; PT-gliadin; pepsin-trypsin digest of gliadin; TCC; T-cell clone; TCL; T-cell line; TCR; T-cell receptor; TG2; transglutaminase 2;
Browning deficiency and low mobilization of fatty acids in gonadal white adipose tissue leads to decreased cold-tolerance of transglutaminase 2 knock-out mice
Keywords: ADIPOQ; Adiponectin; AT; adipose tissue; BAT; brown adipose tissue; WAT; white adipose tissue; SCAT; subcutaneous white adipose tissue; FFA; free fatty acid; GONAT; gonadal white adipose tissue; CIDEA; cell death-inducing DFFA-like effector a; DIO2; type
Mineralization-inhibiting effects of transglutaminase-crosslinked polymeric osteopontin
Keywords: OPN; osteopontin; SIBLING; Small, Integrin-Binding LIgand N-linked Glycoprotein; PHEX; Phosphate-regulating gene with Homologies to Endopeptidase on the X chromosome; TGs; transglutaminases; TG2; transglutaminase 2 (tissue transglutaminase); iTG2; inactiv
No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease
Keywords: Pathology; Healing; Inflammation; Treatment; AE; adverse events; ANCOVA; analysis of covariance; CDSD; celiac disease symptom diary; DGP; deamidated gliadin peptide; GFD; gluten-free diet; GI; gastrointestinal; ICDSQ; Impact of Celiac Disease Symptoms Que
Development of carbon-11 labeled acryl amides for selective PET imaging of active tissue transglutaminase
Keywords: Tissue transglutaminase; TG2; Carbon-11; Carbonylation; [11C]acryl amides; MDA-MB-231
Influence of dietary components on Aspergillus niger prolyl endoprotease mediated gluten degradation
Keywords: AN-PEP; Aspergillus niger prolyl endoprotease; CD; celiac disease; TG2; tissue transglutaminase; GFD; gluten free diet; PEP; bacterial propyl oligopeptidase; PPU; proline protease unit; PVDF; polyvinylidene difluoride; Diet; Endoprotease; Gluten; Oral sup
Tissue transglutaminase promotes serotonin-induced AKT signaling and mitogenesis in pulmonary vascular smooth muscle cells
Keywords: MDC; monodansylcadaverine; PASMC; pulmonary arterial smooth muscle cells; 5-HT; 5-hydroxytryptamine (serotonin); SERT; serotonin transporter; TG2; transglutaminase 2 aka tissue transglutaminase; Transglutaminase 2; AKT; S6K; S6; Serotonin; SERT;
Type 2 Transglutaminase, mitochondria and Huntington's disease: Menage a trois
Keywords: TG2; Mitochondria; Neurodegeneration; Mitophagy; IF1
Glutenase ALV003 Attenuates Gluten-Induced Mucosal Injury in Patients With Celiac Disease
Keywords: Duodenal Biopsy; Drug Treatment; Morphometry; Clinical Trial; AE; adverse event; CDQ; Celiac Disease Questionnaire; DGP; deamidated gliadin peptide; ELISA; enzyme-linked immunosorbent assay; EMA; endomysial antibody; GSRS; gastrointestinal symptom rating
A possible role of transglutaminase 2 in the nucleus of INS-1E and of cells of human pancreatic islets
Keywords: FPIS; first phase insulin secretion; TG2; transglutaminase 2.; Transglutaminase 2; Insulin secretion; Calcium concentration; β-Cell; INS-1E; Human islet;
Transglutaminase 2 as a novel activator of LRP6/β-catenin signaling
Keywords: Fzd; Frizzled; LRP5/6; LRP5 or LRP6; APC; Adenomatosis Polyposis Coli; GSK3; Glycogen Synthase Kinase 3; TG2; Tissue transglutaminase; VSMCs; Vascular smooth muscle cells; TGases; Transglutaminases; ECM; Extracellular matrix; MEFs; Mouse embryonic fibrobl
Lysine residues of IGF-I are substrates for transglutaminases and modulate downstream IGF-I signalling
Keywords: TGases; transglutaminases; ECM; extra-cellular matrix; RTK; receptor tyrosine kinases; FXIIIa; factor thirteen transglutaminase; TG2; tissue transglutaminase; SPR; surface plasmon resonance; VN; vitronectin; FN; fibronectin; IGFBPs; IGF binding proteins;
Transglutaminase 2 facilitates or ameliorates HIF signaling and ischemic cell death depending on its conformation and localization
Keywords: TG2; transglutaminase 2; HIF; hypoxia inducible factor; HRE; hypoxia response element; XRE; xenobiotic response element; OGD; oxygen glucose deprivation; NLS; nuclear localization signal; NES; nuclear export signal; CAT; catalytic; ChIP; chromatin immunop
An inhibitor of thrombin activated fibrinolysis inhibitor (TAFI) can reduce extracellular matrix accumulation in an in vitro model of glucose induced ECM expansion
Keywords: TAFI; thrombin activated fibrinolytic inhibitor; CKD; chronic kidney disease; ESRD; end stage renal disease; ECM; extracellular matrix; MMP; matrix metalloproteinase; TG2; tissue transglutaminase; TG; transglutaminase; TEC; tubular epithelial cell; DMEM;
Breast tumor and stromal cell responses to TGF-β and hypoxia in matrix deposition
Keywords: 2-DG; 2-deoxy-D-glucose; 2-DG6P; 2-deoxy-d-glucose-6-phosphate; AHR; aryl hydrocarbon receptor; Arg1; arginase 1; ARNT; AHR nuclear translocator; bFGF; basic fibroblast growth factor; CAF; cancer associated fibroblast; CCL5; C-C chemokine ligand 5; CSF-1;
Gliadin Does Not Induce Mucosal Inflammation or Basophil Activation in Patients With Nonceliac Gluten Sensitivity
Keywords: Allergy; Duodenal Immune Response; Diagnostic; In Vitro Challenge; AGA; antigliadin antibodies; a-tTG; anti-tissue transglutaminase antibody; CD; celiac disease; EMA; anti-endomysium antibody; FD; free diet; GFD; gluten-free diet; HC; healthy control; IC
Immunoassay of in vitro activated human tissue transglutaminase
Keywords: TG2; Tissue transglutaminase; Transglutaminase activity; Transamidation; Monoclonal antibodies; All-trans retinoic acid;
Tolerance to Ingested Deamidated Gliadin in Mice is Maintained by Splenic, Type 1 Regulatory T Cells
Keywords: Food Allergy; Mucosal Tolerance Induction; Treg Cells; Immune Regulation; BM-DC; bone marrow-derived dendritic cells; DC; dendritic cell; DTH; delayed-type hypersensitivity; FACS; fluorescence-activated cell sorter; IFN; interferon; IL; interleukin; MLN
Inhibition of tissue transglutaminase sensitizes TRAIL-resistant lung cancer cells through upregulation of death receptor 5
Keywords: TG2; tissue transglutaminase; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; DR4 (DR5); death receptor 4 (5); NF-κB; nuclear factor kappa B; siRNA; small interfering RNA; Resistance to apoptosis; Tumor necrosis factor-related apoptosis-i
Celiac Disease without Villous Atrophy in Children: A Prospective Study
Keywords: EmA; Endomysial antibodies; HLA; Human leukocyte antigen; IEL; Intraepithelial lymphocyte; Ig; Immunoglobulin; TG2; Tissue transglutaminase 2; Vh/CrD; Villous height crypt depth ratio;
Development of an isoenzyme-specific colorimetric assay for tissue transglutaminase 2 cross-linking activity
Keywords: TG2; Tissue transglutaminase; Colorimetric assay; Solid-phase assay; Spermine; TG2-specific assay;
Mapping of gluten T-cell epitopes in the bread wheat ancestors: Implications for celiac disease
Keywords: αG; α-gliadin; CT; chymotrypsin; TG2; tissue transglutaminase;
Celiac Disease Genetics: Current Concepts and Practical Applications
Keywords: HLA; human leukocyte antigen; IELs; intraepithelial lymphocytes; IFN-γ; interferon-γ; IL; interleukin; MHC; major histocompatibility complex; TG2; transglutaminase 2 or tissue transglutaminase; TNF; tumor necrosis factor;
Unexpected Role of Surface Transglutaminase Type II in Celiac Disease
Keywords: bio-MDC; biotinylated monodansylcadaverine; FITC; fluorescein isothiocyanate; mAb; monoclonal antibody; sTG2; surface transglutaminase type II; TCD; treated patients with celiac disease; TG2; transglutaminase type II;