Molecular cloning and functional characterization of avian interleukin-19
Keywords: Avian immunity; IL-19; IL-10; Th2; Inflammation; Chicken;
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IL-10 is pathogenic during the development of coxsackievirus B4-induced chronic pancreatitis
Keywords: IL-10; Coxsackievirus; Pancreatitis; Transcriptional profiling; Cytokines; TLR; Th1; Th2; Th17
Antimetastatic and Immunomodulating Effect of Water Extracts From Various Mushrooms
Keywords: colon26-L5 cell; IFN-γ; lung metastasis; Th1; Th2
Selective control of SIRP-α-positive airway dendritic cell trafficking through CD47 is critical for the development of TH2-mediated allergic inflammation
Keywords: Dendritic cells; migration; CD103; allergic inflammation; TH2; CD47; SIRP-α; BALF; Bronchoalveolar lavage fluid; BMDC; Bone marrow-derived dendritic cell; DC; Dendritic cell; FITC; Fluorescein isothiocyanate; Foxp3; Forkhead box protein 3; LN; Lymph no
Eosinophilic gastrointestinal disease and peanut allergy are alternatively associated with IL-5+ and IL-5â TH2 responses
Keywords: Food allergy; peanut; T cell; TH2; eosinophil-associated gastrointestinal disease; IL-4; IL-5; flow cytometry; AEG; Allergic eosinophilic gastroenteritis; EG; Eosinophilic gastroenteritis; EGID; Eosinophil-associated gastrointestinal disorder; EoE; Eosino
Human embryo immune escape mechanisms rediscovered by the tumor
Keywords: Embryo immune escape; Tumor immune escape; Tumor immunosuppression; DC; dendritic cell; HLA; human leukocyte antigen; KIR; killer cell Ig-like inhibitory receptor; MHC; major histocompatibility complex; NK; natural killer; Th1; helper-1 T lymphocyte; Th2;
Cancer and Pregnancy: Parallels in Growth, Invasion, and Immune Modulation and Implications for Cancer Therapeutic Agents
Keywords: CTL; CD8+ T cytotoxic lymphocyte; DC; dendritic cell; EVT; extravillous trophoblast; HLA; human leukocyte antigen; IL; interleukin; NK; natural killer; TH1; helper T cell type 1; TH2; helper T cell type 2; Treg; regulatory T cell; uNK; uterine NK;
Immunoregulatory properties of vasoactive intestinal peptide in human T cell subsets: Implications for rheumatoid arthritis
Keywords: VIP; Rheumatoid arthritis; PBL; Human; Th1; Th2; IL-10; Treg
Interleukin-18 enhances a Th2 biased response and susceptibility to Leishmania mexicana in BALB/c mice
Keywords: Interleukin-18; Leishmania mexicana; Th2
Activation of human monocyte-derived dendritic cells by Burkholderia pseudomallei does not require binding to the C-type lectin DC-SIGN
Keywords: Melioidosis; Burkholderia pseudomallei; Dendritic cells; DC-SIGN; TH1; TH2;
Ginger prevents Th2-mediated immune responses in a mouse model of airway inflammation
Keywords: Ginger; Immune response; Cytokine; Th2
Can type-1 responses against intracellular pathogens be T helper 2 cytokine dependent?
Keywords: Th1; Th2; IL-4; IL-13; Leishmania
Oxidative microenvironment exerts an opposite regulatory effect on cytokine production by Th1 and Th2 cells
Keywords: Th1; Th2; Allergy; Oxidative stress; Cytokines;
Helicobacter pylori Vaccine: From Past to Future
Keywords: Cag; cytotoxin-associated gene; CT; cholera toxin; LT; heat-labile toxin; NAP; neutrophil-activating protein; rUre; recombinant urease; TH1; helper T cell type 1; TH2; helper T cell type 2; VacA; vacuolating cytotoxin A;
Therapeutic approaches for control of transcription factors in allergic disease
Keywords: Transcription factors; asthma; atopic dermatitis; signal transducer and activator of transcription 6; GATA3; TH2; nuclear factor of activated T cells; nuclear factor κB; glucocorticoid receptorAP-1, Activator protein 1; CsA, Cyclosporin A; GR, Glucocortic
HIV-1 reverse transcriptase artificially targeted for proteasomal degradation induces a mixed Th1/Th2-type immune response
Keywords: HIV-1; DNA vaccine; Proteasome; Reverse transcriptase; PEST signal; Th1; Th2; Cytokines
Effects of a Th1- versus a Th2-biased immune response in protection against Helicobacter pylori challenge in mice
Keywords: Th1; Th2; H. pylori; Gastric immunity; Vaccine; Adjuvant;
Interleukin-13 mucosal production in Helicobacter pylori-related gastric diseases
Keywords: Helicobacter pylori; Gastric carcinogenesis; IL-13; Local immune response; Th2; ELISPOT assay
Augmented Phl p 5-specific Th2 response after exposure of dendritic cells to allergen in complex with specific IgE compared to IgG1 and IgG4
Keywords: Antibody-mediated responses; Th2; IgE; Phl p 5; Allergic Rhinitis; Dendritic cells; T-cells; Antibody arrays;
Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease
Keywords: Airway inflammation; chronic rhinosinusitis; nasal polyps; eosinophils; TH2; TH17; regulatory T cells; IL-17A; TGF-β1; Foxp3Be NP, Nasal polyps from Belgian patients; Be CO, Control tissue from Belgian patients; CRSwNP, Chronic rhinosinusitis with nasal p
CD4+ T helper responses in squamous cell carcinoma of the head and neck
Keywords: SCCHN; squamous cell carcinoma of the head and neck; MLTC; mixed lymphocyte-tumor cell cultures; wt; wild type; PBMCs; peripheral blood mononuclear cells; CTLs; cytotoxic T lymphocytes; PBLs; peripheral blood lymphocytes; TILs; tumor-infiltrating lymphocy
The roles of IL-10 and TGF-β in controlling IL-4 and IFN-γ production during experimental Fasciola hepatica infection
Keywords: Fasciola hepatica; Cellular immune response; Th2; IL-4; Helminth; Immunomodulation;
Increased circulating paternal antigen-specific IFN-γ- and IL-4-secreting cells during pregnancy in allergic and non-allergic women
Keywords: Pregnancy; Th2; Elispot; MLC;
Th2 Cytokine-Induced Alterations in Intestinal Smooth Muscle Function Depend on Alternatively Activated Macrophages
Keywords: 5-HT; 5-hydroxytryptamine; AAMÏ; alternatively activated macrophage; BEC; S-(2-boronoethyl)-I-cysteine; CAMÏ; classically activated macrophage; Cl2MDP; clodronate; FIZZ; found in inflammatory zone; IFN-γ; interferon-γ; IGF-1; insulin-like growth facto
GATA3 mRNA in ginbuna crucian carp (Carassius auratus langsdorfii): cDNA cloning, splice variants and expression analysis
Keywords: GATA3; T-cell; Th2; Teleost; Splice variant; Ginbuna crucian carp; Transcription factor
TH2 adjuvants: Implications for food allergy
Keywords: Adjuvant; TH2; food allergy; allergen; cholera toxin; helminth; glycan; DC-SIGN; protease; protease activated receptor; superallergen; OX40L; TSLP; T-cell immunoglobulin mucin protein; Notch; Jagged; DeltaAPC, Antigen-presenting cell; CSL, CBF1-suppressor
Toll-like receptor 4 and cytokine expression involved in functional immune response in an originally established porcine intestinal epitheliocyte cell line
Keywords: PRRs; pattern recognition receptors; PAMPs; pathogen-associated molecular patterns; TLR; Toll-like receptor; PIE; Porcine Intestinal Epitheliocytes; LPS; Lipopolysaccharide; ETEC; Enterotoxigenic Escherichia coli; DIC; differential interference contrast;
Peripheral virus-specific T-cell interleukin-10 responses develop early in acute hepatitis C infection and become dominant in chronic hepatitis
Keywords: HCV; hepatitis C virus; IFN; interferon; PEG-IFNα; pegylated interferon-alpha; PBMC; peripheral blood mononuclear cells; PCR; reverse-transcriptase polymerase chain reaction; PHA; phytohemagglutinin; SD; standard deviation; SFU; spot-forming unit; SOD; s
T-cell effector pathways in allergic diseases: Transcriptional mechanisms and therapeutic targets
Keywords: Transcriptional regulation; T-cell differentiation; TH1; TH2; Treg; TH17; T-bet; GATA-3; Foxp3; RORγτ; atopic disease; asthma; therapeutic strategies; oxidative stress; Nrf2ARE, Antioxidant response element; aTreg, Adaptive T regulatory; c-MAF, Musculoapo
ß-glucans as conductors of immune symphonies
Keywords: Immunostimulants; ß-glucan; Adaptive immunity; Th1; Th2; Th17; Adjuvants; Vaccines; Dectin-1; Toll Like; receptors; Shrimp
Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction
Keywords: Dendritic cells; TH1; TH2; Toll-like receptors; Notch; Jagged-1; Delta-4; STAT-4; STAT-6; IL-4; IL-12; BDCA; Blood dendritic cell antigen; DAPT; N(N-[3,5-difluorophenacetyl-L-alanyl])-S-phenylglycine t-butyl ester; DC; Dendritic cell; iDC; Immature dendri
Antibodies to T-cell Ig and mucin domain-containing proteins (Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis
Keywords: Allergic conjunctivitis; Eosinophil; Tim-1; Tim-3; Th2
B7-H3 regulates the development of experimental allergic conjunctivitis in mice
Keywords: Allergic conjunctivitis; Eosinophil; B7-H3; Th1; Th2
T-cell Ig and mucin domain-containing protein (Tim)-2 regulates murine allergic conjunctivitis during the effector phase
Keywords: Allergic conjunctivitis; Eosinophil; Tim-2; Th2
Increased expression and activation of IL-12-induced Stat4 signaling in the mucosa of ulcerative colitis patients
Keywords: IBD; IL-12; IL-23; IFN-γ; Stat4; Th1; Th2; Th17; Ulcerative colitis
Thymic stromal lymphopoietin and OX40 ligand pathway in the initiation of dendritic cell–mediated allergic inflammation
Keywords: TSLP; dendritic cells; TH2; allergy; asthma; atopic dermatitis; OX40CD40L, CD40 ligand; DC, Dendritic cell; IL-7R, IL-7 receptor; mDC, Myeloid dendritic cell; OX40L, OX40 ligand; RXR, Retinoid X receptor; TLR, Toll-like receptor; TSLP, Thymic stroma lymph
HLA-DRB1 alleles control allergic bronchopulmonary aspergillosis–like pulmonary responses in humanized transgenic mice
Keywords: Allergic bronchopulmonary aspergillosis; Aspergillus fumigatus; TH2; HLA-DR; pulmonary immunity; MHC; asthma; cystic fibrosis; eosinophilia; transgenicABPA, Allergic bronchopulmonary aspergillosis; BAL, Bronchoalveolar lavage; CF, Cystic fibrosis; MLN, Me
TH17 cells in the big picture of immunology
Keywords: Tolerance; differentiation; TH17; TH2; transcription factor; allergyTreg, T regulatory
Prevention of lethal experimental infection of C57BL/6 mice by vaccination with Brucella abortus strain RB51 expressing Neospora caninum antigens
Keywords: Neospora caninum; Brucella abortus strain RB51; Vaccine; Mice; Lethal challenge; Th1; Th2;
T cell populations propagating in the peripheral blood of patients with drug eruptions
Keywords: Drug eruption; Stevens–Johnson syndrome; Th1; Th2; Erythema multiforme; Drug-induced hypersensitivity syndrome
Eosinophilic Esophagitis: Is It All Allergies?
Keywords: EE; eosinophilic esophagitis; EGD; esophagogastroduodenoscopy; IL; interleukin; PPV; positive predictive value; RAST; radioallergosorbent test; STAT-6; signal transducer and activator of transcription 6; TH2; T helper type 2;
Specific immune response to HBsAg is enhanced by β-glucan oligosaccharide containing an α-(1 → 3)-linked bond and biased towards M2/Th2
Keywords: β-glucan; HBsAg; Cytokine; Th2; Adjuvant; Innate immunity
Histamine affects STAT6 phosphorylation via its effects on IL-4 secretion: Role of H1 receptors in the regulation of IL-4 production
Keywords: Th1; T-helper type 1 lymphocyte; Th2; T-helper type 2 lymphocyte; STAT; Signal Transducer and Activator of Transcription; PMA; phorbol 12 myristate 13-acetate; H1 receptor; histamine receptor 1; H2 receptor; histamine receptor 2; H3 receptor; histamine re
Molecular Targets in Pulmonary Fibrosis
Keywords: myofibroblast; pulmonary fibrosis; therapy; ALK-5; activin-like kinase receptor-5; CTGF; connective tissue growth factor; ECM; extracellular matrix; EMT; epithelial-mesenchymal transition; FIZZ; found in inflammatory zone; IFN; interferon; IL; interleukin
The role of T helper cells in neuroprotection and regeneration
Keywords: Th2; Protective autoimmunity; Immunosuppression; CNS wound healing; Traumatic brain injury; Spinal cord injury
T-cell responses to allergens
Keywords: Allergens; TH1; TH2; effector memory T cells; central memory T cells; regulatory T cells; LPS; lipid antigens; immunostimulatory DNA sequences; T-cell epitopes; peptide vaccinesAD, Atopic dermatitis; APC, Antigen-presenting cell; CLA, Cutaneous lymphocyte
Identification of an immune-responsive mesolimbocortical serotonergic system: Potential role in regulation of emotional behavior
Keywords: depression; hippocampus; prefrontal cortex; raphe; 5-HT; vagus; ANOVA; analysis of variance; AP; area postrema; c-Fos-ir; c-Fos-like-immunoreactive; DR; dorsal raphe nucleus; DRC; dorsal raphe nucleus, caudal part; DRI; dorsal raphe nucleus, interfascicul
Novel human polysaccharide adjuvants with dual Th1 and Th2 potentiating activity
Keywords: Adjuvant; Vaccine; Inulin; Complement; Cellular; Immune; Th1; Th2
Concomitant chronic inflammatory demyelinating polyneuropathy and myasthenia gravis following cytomegalovirus infection
Keywords: Chronic inflammatory demyelinating polyneuropathy; Chronic inflammatory demyelinating polyradiculoneuropathy; Myasthenia gravis; Cytomegalovirus infection; Th1; Th2