Keywords: α; 7nAChRAlpha7 nicotinic acetylcholine receptor; α; -CGRPAlpha-calcitonin gene-related peptide; AT; 1/2Angiotensin 1/2 receptor; AVP; Arginine vasopressin; BDL; Bile duct ligation; CLR; Calcitonin-like receptor; CNS; Central nervous system; cAMP; Cycli
مقالات ISI (ترجمه نشده)
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Keywords: NF; normal fibroblasts; KF; keloid fibroblasts; DMEM; Dulbecco's modified eagle medium; CM ASCs-CM; conditioned medium from nutrient poor, adipose tissue-derived mesenchymal stem cells; BSA; bull serum albumin; Brdu; 5-bromo-2â²-deoxyuridine; TGF; tran
Keywords: Cancer-associated fibroblasts; Intratumoral inflammatory cells; MMPs; Molecular subtype; TIMPs;
Keywords: Butein (PubChem CID: 5281222); Cardamonin (PubChem CID: 641785); 2â²,4â²-Dihydroxy-6â²-methoxy-3â²,5â²-dimethylchalcone (PubChem CID: 10424762); Flavokawain B (PubChem CID: 5356121); Hydroxysafflor Yellow A (PubChem CID: 6443665); Naringenin Chalcone
Keywords: ECM; extracellular matrix; ADAM; a disintegrin and metalloproteinase; ADAMTS; a disintegrin and metalloproteinase with thrombospondin-like motifs; CS; chondroitin sulfate; DS; dermatan sulfate; EMT; epithelial-to-mesenchymal transition; FACIT; fibril-asso
Keywords: α-SMA; α smooth muscle actin; CGRP; calcitonin gene related peptide; CTGF; connective tissue growth factor; DETCs; dendritic epidermal T cells; ECM; extracellular matrix; EGF; epidermal growth factor; eNOS; endothelial nitric oxide synthase; EPCs; endot
Keywords: AAC; abdominal aortic constriction; ADAMS; a disintegrin and metalloproteases; ADAMTS; a distingetrin and metalloproteinase with a thrombospondin domain; Ang II; angiotensin II; BM; basement membrane; BMP-1; bone morphogenic protein-1; CITP; carboxy-termi
Keywords: Depressive disorder; Inflammation; ECT; Immune; Cortisol; ACTH; Adrenocorticotropic hormone; AVP; arginine vasopressin; BDI; Beck Depression Inventory; BL-BT; Bilateral-Bitemporal; BP; Bipolar Disorders; CMI test; serotonin uptake inhibitor clomipramine;
Keywords: HF; hepatic fibrosis; HSC; hepatic stellate cells; ECM; extracellular matrix; MMPs; matrix degrading metalloproteinases; TIMPs; tissue inhibitors of metalloproteinases; TGF-β; transforming growth factor-beta; NK; Natural killer; NKT; NK like T; NKG2D; na
Keywords: ECM; extracellular matrix; AST; aspartate aminotransferase; ALT; alanine aminotransferase; AP; alkaline phosphatase; MMPs; metalloproteinases; TIMPs; tissue inhibitors of metalloproteinases; NIL; neurointermediate pituitary lobectomy; R; cirrhosis reversi
Keywords: CLCN5 gene; Dent's disease; Fibrosis; Chronic renal failure; Metalloproteases; TIMPs
Keywords: Vascular smooth muscle cell; Embryonic stem cells; Induced pluripotent stem cells; Lateral plate mesoderm; Neural crest; Serum-free; Coronary; VSMCs; vascular smooth muscle cells; VEGF; vascular endothelial growth factor; PAH; pulmonary arterial hypertens
Keywords: Hcc and liver disease; Breast carcinoma; MMPs; TIMPs
Keywords: Photoperiod; Recrudescence; MMP; TIMPs; EGFR;
Keywords: VEGF; vascular endothelial growth factor; TGF-β; transforming growth factor-β; ECM; extracellular matrix; EC; endothelial cell; SPARC; secreted protein acidic and rich in cysteine; PG; proteoglycan; GAG; glycosaminoglycan; SLRP; small leucine-rich prote
Keywords: CFs; Cardiac fibroblasts; CMs; Cardiomyocytes; H; Hypoxia; H/R; Hypoxia-reoxygenation; I/R; Ischemia-reperfusion; MMPs; Metalloproteinases; R; Reoxygenation; Secr; CF secretome; Secr ÎTIMP-1; CF secretome depleted from TIMP-1; TIMPs; Tissue inhibitor
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families
Keywords: Hepatocellular carcinoma; Sorafenib; Regorafenib; Levnatinib; Invasion; Metastasis; Hepatocellular carcinoma; HCC; Matrix metalloproteinases; MMPs; Tissue inhibitors of MMPs; TIMPs; Extracellular matrix; ECM; Receptor tyrosine kinases; RTKs; Vascular endo
Increased fibrosis: A novel means by which GH influences white adipose tissue function
Keywords: GH; growth hormone; GHR; growth hormone receptor; GHRKO; growth hormone receptor knockout; FaGHRKO; fat growth hormone receptor knockout; LiGHRKO; liver growth hormone receptor knockout; IGF-1; insulin-like growth factor 1; WAT; white adipose tissue; ECM;
Involvement of matrix metalloproteinases (MMP-2, -7, -9) and their tissue inhibitors (TIMP-2, -3) in the regression of chicken postovulatory follicles
Keywords: MMPs; TIMPs; Caspases; Postovulatory follicles; Chicken;
Expression and modulation of S100A4 protein by human mast cells
Keywords: COPD; chronic obstructive pulmonary disease; EMT; epithelial to mesenchymal transition; FICZ; 6-formylindolo[3,2-b]carbazole; FC; flow cytometry; FSP1; fibroblast-specific protein 1; IF; immunofluorescence; IHC; immunohistochemistry; IntDen; integrated fl
Mogroside IVE attenuates experimental liver fibrosis in mice and inhibits HSC activation through downregulating TLR4-mediated pathways
Keywords: α-SMA; α-smooth muscle actin; ALT; alanine aminotransferase; AST; aspartate aminotransferas; CCl4; carbon tetrachloride; Col I; collagen I; ECM; extracellular matrix; HIF; hypoxia inducible factor; HSCs; hepatic stellate cells; JNK; c-Jun N-terminal kin
Rosmarinic acid influences collagen, MMPs, TIMPs, glycosylation and MUC1 in CRL-1739 gastric cancer cell line
Keywords: Collagen; Glycosylation; MMPs; MUC1; Rosmarinic acid; TIMPs;
Dysregulation of fibrosis related genes in HCV induced liver disease
Keywords: Alb; Albumin; ALK PH; Alkaline phosphatase; ALT; Alanine amino transferase; APO; Apolipoprotein; AST; Aspartate transaminase; AUC; Area Under Curve; BIL.D; Direct bilirubin; BIL T; Total bilirubin; BMI; Body mass index; cDNA; Complementary DNA; CTGF; Conn
The apparent competitive action of ECM proteases and cross-linking enzymes during fibrosis: Applications to drug discovery
Keywords: ADAMs; a disintegrin and metalloproteinases; ADAMTS; ADAMs with thrombospondin motifs; BALF; bronchoalveolar lavage fluid; BAPN; β-aminopropionitrile; CD; Crohn's disease; ECM; extracellular matrix; EMT; epithelial to mesenchymal transition; EndoMT; endo
Biomaterial Cues to Direct a Pro-regenerative Phenotype in Macrophages and Schwann Cells
Keywords: CNTF; ciliary neurotrophic factor; CSPG; chondroitin sulfate proteoglycan; DRG; dorsal root ganglia; PNI; peripheral nerve injury; ECM; extracellular matrix; HA; hyaluronic acid; IFNy; interferon-y; iNOS; inducible nitric oxide synthase; LPS; lipopolysacc
MMP-12 and TIMP Behavior in Symptomatic and Asymptomatic Critical Carotid Artery Stenosis
Keywords: Critical carotid artery stenosis; stroke; MMP-12; TIMPs;
Matrix Metalloproteinases (MMPs) in Liver Diseases
Keywords: Col; collagen; ECM; extra cellular matrix; GBD; global burden of disease; HCC; hepato-cellular carcinoma; IRI; ischemia and reperfusion injury; MMP; matrix metalloproteases; NAFLD; non-alcoholic fatty liver disease; NFkB; nuclear factor kappa-B; TNF; tumo
GPR120 in adipocytes has differential roles in the production of pro-inflammatory adipocytokines
Keywords: Obesity; Extracellular matrix remodeling factor; Protein kinase C; Toll-like receptors; Ï-3 polyunsaturated fatty acids; Ï-3 PUFA; Ï-3 polyunsaturated fatty acid; DHA; docosahexaenoic acid; ECM; extracellular matrix; EPA; eicosapentaenoic acid; GPR120;
Lucidone Promotes the Cutaneous Wound Healing Process via Activation of the PI3K/AKT, Wnt/β-catenin and NF-κB Signaling Pathways
Keywords: CDK; cyclin dependent kinase; COX; cyclooxygenase; ECM; extracellular matrix; EMT; epithelial-mesenchymal transition; GSK3β; glycogen synthase kinase 3 beta; ICAM; intercellular adhesion molecule; iNOS; inducible nitric oxide synthase; LY294002; (4-morph
Milk Fat Globule-EGF Factor 8, Secreted by Mesenchymal Stem Cells, Protects Against Liver Fibrosis in Mice
Keywords: Mouse Model; Signal Transduction; MMP; Decorin; MSC; mesenchymal stem/stromal cell; ECM; extracellular matrix; TGF; transforming growth factor; HSCs; hepatic stellate cells; MMPs; matrix metalloproteinases; TIMPs; tissue inhibitors of metalloproteinases;
Adipose extracellular matrix remodelling in obesity and insulin resistance
Keywords: ECM; extracellular matrix; HFD; high fat diet; OPN; osteopontin; HA; hyaluronan; THBS; thrombospondin; MMPs; matrix metalloproteinases; MT-MMPs; membrane-type matrix metalloproteinases; TIMPs; tissue inhibitors of metalloproteinases; HOMA-IR; homoeostasis
Immunohistochemical analysis of the gingiva with periodontitis of type I plasminogen deficiency compared to gingiva with gingivitis and periodontitis and healthy gingiva
Keywords: plg; plasminogen; plgdef; Type I plasminogen deficiency; PMN; polymorphonuclear neutrophil; GCF; gingival crevicular fluid; elastase 2; neutrophil elastase; ECM; extracellular matrix; MMP-3; matrix-metalloproteinase 3 stromelysin 1; MMP-7; matrix-metallop
The interplay between hepatic stellate cells and hepatocytes in an in vitro model of NASH
Keywords: HSC; hepatic stellate cells; ECM; extracellular matrix; FFA; free fatty acids; SCC; Simultaneous Co-Culture; NAFLD; non-alcoholic fatty liver disease; MMPs; matrix metalloproteinases; TIMPs; inhibitors of metalloproteinases; MMP2; gelatinase A; COL1; coll
Deleterious effects of benomyl and carbendazim on human placental trophoblast cells
Keywords: MMPs; matrix metalloproteinases; TIMPs; tissue inhibitors of MMPs; uPA; urokinase plasminogen activator; PAI-1; plasminogen activator inhibitor-1; Benomyl; Carbendazim; Benzimidazole fungicides; Placenta; Trophoblast; HTR-8 cells; Toxicity;
Androgen receptors and experimental bone loss - an in vivo and in vitro study
Keywords: GnRH; Gonadotropin-releasing hormone; sIL6r; Soluble interleukin-6 receptor; IL-6; Interleukin-6; IL-1β; Interleukin-1β; TNF; Tumor necrosis factor; MIP; Macrophage inflammatory protein; DHT; Dihydrotestosterone; GPR30; G-protein coupled receptor-30; Bo
The role of TIMPs in regulation of extracellular matrix proteolysis
Keywords: Matrix turnover; Metalloproteinases; TIMPs; Fibrosis
Novel expression and regulation of TIMP-1 in Epstein Barr virus-infected cells and its impact on cell survival
Keywords: EBV; Epstein-Barr virus; LCLs; lymphoblastoid cell lines; TIMPs; Tissue inhibitors of metalloproteinases; BL; Burkitt׳s lymphoma; HD; Hodgkin׳s disease; NPC; nasopharyngeal carcinoma; MMPs; matrix metalloproteinases; PTLD; post-transplant lymphoprolif
Histone deacetylases in cardiac fibrosis: Current perspectives for therapy
Keywords: HDACs; Histone deacetylases; ECM; Extracellular matrix; α-SMA; α-smooth muscle actin; HATs; Histone acetyltransferases; TGF-β1; Transforming growth factor β1; PDGF; Platelet-derived growth factor; FGF; Fibroblast growth factor; TIMPs; Tissue inhibitor
Redox regulation of MMP-3/TIMP-1 ratio in intestinal myofibroblasts: Effect of N-acetylcysteine and curcumin
Keywords: MMPs; Matrix metalloproteinases; TIMPs; Tissue inhibitors of metalloproteinases; CD; Crohn׳s disease; ISEMFs; Intestinal subepithelial myofibroblasts; GSH; Glutathione; GSH/GSSG ratio; Glutathione/oxidized glutathione ratio; NAC; N-acetylcysteine; (TNF)Î
EGFR and HER2 exert distinct roles on colon cancer cell functional properties and expression of matrix macromolecules
Keywords: EGFR; epidermal growth factor receptor; HER2; human epidermal receptor 2; ECM; extracellular matrix; MMPs; matrix metalloproteinases; MT-MMPs; membrane type-matrix metalloproteinases; TIMPs; tissue inhibitor of matrix metaloproteinases; uPA; plasminogen a
GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity
Keywords: PCa; prostate cancer; GPNMB; non-metastatic glycoprotein melanoma protein B; OA; osteoactivin; MMPs; metalloproteinases; TIMPs; tissue inhibitors of matrix metalloproteinases; NGF; Nerve Growth Factor; Q-RT-PCR; quantitative real time-PCR; siRNA; small in
CD1d expressed in mast cell surface enhances IgE production in B cells by up-regulating CD40L expression and mediator release in allergic asthma in mice
Keywords: α-Gal; α-galactosylceramide; APC; antigen presenting cells; BAL; Bronchoalveolar lavage; BMMCs; Bone marrow-derived mast cells; CCL2; Chemokine ligand 2; CCR2; Chemokine receptor 2; CD1dâ/â; CD1d KO; LTs; leukotrienes; MMPs; Matrix metalloproteinase
Matrix metalloproteinase (MMP)-2 gene polymorphisms affect circulating MMP-2 levels in patients with migraine with aura
Keywords: MMPs; Matrix metalloproteinases; BBB; Blood-brain barrier; TIMPs; Tissue inhibitor of MMPs; CSD; Cortical spreading depression; MWA; Migraine without aura; MA; Migraine with aura; RT-PCR; Real time-polymerase chain reaction; ELISA; Enzyme-linked immunos
Transcriptional profiling in rats and an ex vivo analysis implicate novel beneficial function of egg shell membrane in liver fibrosis
Keywords: α-Sma; smooth muscle-α-actin; BHLHB2; basic helix-loop-helix domain containing class B2; COL1A1; collagen, type I, alpha 1; COL1A2; collagen, type I, alpha 2; CYP7A1; cytochrome P450 Family 7 Subfamily A Polypeptide 1; DMEM; Dulbecco's modified eagleâ
Expression of matrix metalloproteinase-13 (MMP-13) in the testes of growing and adult chicken
Keywords: MMP, matrix metalloproteinase; TIMP, tissue inhibitor of MMPMMP-13; TIMPs; Chicken; Testis; Seminiferous tubules; Postnatal development
Metalloproteinases and eye diseases
Keywords: Metalloproteinases; TIMPs; Diabetic retinopathy; Corneal neovascularization; Trabeculectomy; Superior limbic keratoconjunctivitis; Dry eye disease; Age-related macular degeneration
Age-related divergent remodeling of the cardiac extracellular matrix in heart failure: Collagen accumulation in the young and loss in the aged
Keywords: Heart failure; Aging; Extracellular matrix; Fibrosis; TIMPs;
Polyprenols from Taxus chinensis var. mairei prevent the development of CCl4-induced liver fibrosis in rats
Keywords: ECM; extracellular matrix; HSCs; activated hepatic stellate cells; α-SMA; α-smooth muscle actin; MMPs; matrix metalloproteinases; TIMPs; tissue inhibitors of matrix metalloproteinases; PDGF; platelet-derived growth factor; TGF-β1; transforming growth f
Matrix metalloproteinases in skeletal muscles: Friends or foes?
Keywords: MMPs; TIMPs; Muscle remodeling; Neuromuscular diseases; Muscular dystrophy; Cell therapy; Cell migration;
Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid
Keywords: BPs; bisphosphonates; ZOL; zoledronate; ECM; extracellular matrix; HA; hyaluronan; MMP; matrix metalloproteinase; PG; proteoglycan; MT-MMP; membrane-type MMP; TIMPs; tissue inhibitors of MMPs; COL I; collagen I; COL II; collagen II; COL-IV; collagen IV; F