دانلود مقالات ISI درباره توپو I + ترجمه فارسی

Cell cycle-dependent positive and negative functions of Fun30 chromatin remodeler in DNA damage response

Keywords: توپو I; CPT; camptothecin; DDC; DNA damage checkpoint; DDT; DNA damage tolerance; DSB; double stranded DNA break; G6PD; Glucose-6-phosphate dehydrogenase; HR; homologous recombination; HU; hydroxyurea; MMS; methyl methanesulfonate; ssDNA; single stranded DNA; TLS

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Human Topoisomerase I mediated cytotoxicity profile of l-valine-quercetin diorganotin(IV) antitumor drug entities

Keywords: توپو I; Quercetin pharmacophore; L-/d-valine; Organotin(IV); In vitro DNA binding studies; Denaturation; pBR322 cleavage; Topo I inhibition; Cytotoxic activity; CD; Circular dichroism; CT-DNA; Calf thymus DNA; Q; Quercetin; Topo I; Topoisomerase I; EB; Ethidiu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Design, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors

Keywords: توپو I; Anti-cancer; Topo I; Synthesis; Inhibitor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular modelling approach to evaluate poisoning of topoisomerase I by alternariol derivatives

Keywords: توپو I; AOH; alternariol; AME; alternariol-methyl ether; ALT; altenuene; iALT; isoaltenuene; LBVS; ligand based virtual screening; Topo; topoisomerase; Topo I; topoisomerase I; Topo II; topoisomerase II; Molecular modelling; Alternaria metabolites; Alternariol; P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Design and total synthesis of Mannich derivatives of marine natural product lamellarin D as cytotoxic agents

Keywords: توپو I; Lamellarin D; Mannich; Derivative; Anti-cancer; Topo I; Structure–activity relationshipsAFIYYJXMFAMKQJ-BGXARLBTSA-N; ATHLLZUXVPNPAW-UHFFFAOYSA-N; FLDKPFLIGAHQIB-NHCYNETQSA-N; KWOMCLUWRYZJPM-UHFFFAOYSA-N; BVCSMXWXARRGKM-UHFFFAOYSA-N; JVTZFYYHCGSXJV-UHFFFAO

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and structure elucidation of a cobalt(II) complex as topoisomerase I inhibitor: In vitro DNA binding, nuclease and RBC hemolysis

Keywords: توپو I; CT DNA binding; pBR322 DNA cleavage; T4 DNA ligase assay; Topo I inhibition activity; Molecular docking; UV-Vis; UV-visible; CT DNA; calf thymus DNA; Tris; tris(hydroxymethyl)aminomethane; EB; ethidium bromide; Hmpca; 9-methyl-[1,10]phenanthroline-2-c

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Oxo-heterocyclic fused naphthalimides as antitumor agents: Synthesis and biological evaluation

Keywords: توپو I; Oxo-heterocyclic; Naphthalimides; Antitumor agents; Topo I; Topo II; DNA intercalationCD, circular dichroism; CPT, camptothecin; ctDNA, calf thymus DNA; kDNA, kinetoplast DNA; SAR, structure–activity relationship

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Nick-containing oligonucleotides as human topoisomerase I inhibitors

Keywords: توپو I; Topo I; topoisomerase I; Oligonucleotide; ON; IC50; the concentration of a drug that is required for 50% inhibition of the activity; Human topoisomerase I; Enzyme inhibitor; Stable hairpins; Nick oligonucleotides;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of poly(ADP-ribose) polymerase-1 as the OXPHOS-generated ATP sensor of nuclei of animal cells

Keywords: توپو I; Adenylate kinase; PARP-1; OXPHOS; Topo I; mRNA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Poly(ADPR)polymerase-1 signalling of the DNA damage induced by DNA topoisomerase I poison in D54p53wt and U251p53mut glioblastoma cell lines

Keywords: توپو I; Glioblastoma cells; Topotecan; NU1025; PARP-1; TOPO I; p53; p21

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Photoinduced transformation of camptothecin in the presence of iron(III) ions

Keywords: توپو I; CPT; camptothecin; DBNBS; 3,5-dibromo-4-nitroso-benzenesulfonic acid (sodium salt); DMPO; 5,5-dimethyl-1-pyrroline N-oxide; DMSO; dimethyl sulfoxide; DNA; deoxyribonucleic acid; DPPH; 1,1-diphenyl-2-picrylhydrazyl; EPR; electron paramagnetic resonance; ND

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه