Keywords: ABCC8; ATP Binding Cassette Subfamily C Member 8; CAPN10; calpain 10; Cdkal1; Cdk5 regulatory associated protein 1-like 1; DM; diabetes mellitus; GLIS3; GLIS Family Zinc Finger 3; HMGA1; high mobility group A1; HNF1A; hepatocyte nuclear factor 1A; HNF1Î
مقالات ISI (ترجمه نشده)
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The structurally similar TRFH domain of TRF1 and TRF2 dimers shows distinct behaviour towards TIN2
Keywords: TRF1; TRF2; TRFH domain; TIN2 peptide; Molecular dynamics;
Correlation between telomerase and mTOR pathway in cancer stem cells
Keywords: CSCs; cancer stem cells; mTOR; mammalian target of rapamycin; PI3K; phosphoinositide 3-kinase; AKT; serine/threonine kinase 1; hTERT; human telomerase reverse transcriptase; TERC; telomerase RNA component; GBM; glioblastoma multiforme; TRF1; telomeric rep
TRF1 as a major contributor for telomeres' shortening in the context of obesity
Keywords: Aging; Obesity; Oxidative stress; Shelterin complex; Telomere length; TRF1;
High-throughput gene expression analysis identifies p53-dependent and -independent pathways contributing to the adrenocortical dysplasia (acd) phenotype
Keywords: TPP1; protein encoded by adrenocortical dysplasia gene; Acd; adrenocortical dysplasia gene; acd; adrenocortical dysplasia mutation; p53; transformation related protein 53; DNA; Deoxyribonucleic acid; DC; Dyskeratosis congenita; HHS; Hoyeraal-Hreidarsson s
Interaction of Quindoline derivative with telomeric repeat-containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2
Keywords: ALT; alternative lengthening of telomeres; ATM; ataxia telangiectasia mutated; CD; circular dichroism; ChIP; chromatin immunoprecipitation; DAPI; 4â²,6-diamidino-2-phenylindole; DDR; DNA damage response; DMSO; dimethyl sulfoxide; DSBs; DNA double-strand
TRF2 recruits ORC through TRFH domain dimerization
Keywords: TRF2; telomeric repeat binding factor 2; ORC; origin recognition complex; TRFH; TRF homology; pre-RC; pre-replication complex; G4; G-quadruplex; TRF1; telomeric repeat binding factor 1; lacO; lac operator; LacI; lac repressor; ChIP; chromatin immunoprecip
PARP, transcription and chromatin modeling
Keywords: ABCA1; ATP-binding cassette transporter A1; ADP-ribosylation; adenosine diphosphate ribosylation; ALC1; amplified in-liver-cancer 1; AR; androgen receptor; ARH3; ADP-ribosylhydrolase 3; ART; ADP-ribosyl transferase; ASF/SF2; alternative splicing factor/sp
Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases
Keywords: Tankyrase; PARP; 2-Arylquinazolin-4-one; Wnt; Hydrophobic cavity; ADP; adenosine diphosphate; Bn; benzyl; Cbz; benzyloxycarbonyl; DMAP; 4-dimethylaminopyridine; EDC; Nâ²-ethyl-N-3-(dimethylaminopropyl)carbodiimide; ES; electrospray; HMBC; heteronuclear m
ZSCAN4 and TRF1: A functionally indirect interaction in cancer cells independent of telomerase activity
Keywords: ZSCAN4; TRF1; Cancer; Telomeres; Telomerase; ALT pathway; ALT; alternative lengthening of telomeres; BIFC; bimolecular fluorescence complementation; Co-IP; co-immunoprecipitation; ESC; embryonic stem cells; GST; glutathione S-transferase; PinX1; PIN2/TERF
The G-quadruplex-stabilising agent RHPS4 induces telomeric dysfunction and enhances radiosensitivity in glioblastoma cells
Keywords: G4; G quadruplex; TIF; telomere induced dysfunctional foci; GBM; glioblastoma multiforme; ALT; alternative lengthening of telomeres; hTERT; human telomerase catalytic subunit; PCC; premature chromosome condensation; cPDL; cumulative population doubling le
The splicing factor U2AF65 stabilizes TRF1 protein by inhibiting its ubiquitin-dependent proteolysis
Keywords: TRF1; U2AF65; Fbx4; Telomere; Ubiquitination;
The F-box protein β-TrCP promotes ubiquitination of TRF1 and regulates the ALT-associated PML bodies formation in U2OS cells
Keywords: TRF1; β-TrCP; Ubiquitination; PML;
Post-translational modifications of TRF1 and TRF2 and their roles in telomere maintenance
Keywords: Post-translational modification; Human; Telomere binding proteins; TRF1; TRF2
Electrochemical sensing telomere-bending motions caused by hTRF1
Keywords: Electrochemistry; Telomere bend; TRF1; G-quadruplex; Hemin
Telomere shortening is associated to TRF1 and PARP1 overexpression in Duchenne muscular dystrophy
Keywords: Telomere shortening; TRF1; PARP1; Duchenne muscular dystrophy; Replicative senescence
Intrinsic hTRF1 fluorescence quenching reveals details of telomere DNA binding activity: Impact of DNA length, structure and position of telomeric repeats
Keywords: c-myb; TRF1; Pre-steady state; Kinetics; DNA binding; Fluorescence quenching
Dyskeratosis congenita
Keywords: AML; acute myeloid leukemia; BMF; bone marrow failure; DC; dyskeratosis congenita; HHS; Hoyeraal Hreidarrson syndrome; MDS; myelodysplastic syndrome; OP; osteoporosis; PF; pulmonary fibrosis; POT1; protection of telomeres 1; TIN2; TRF1-interacting nuclear
PML3 interacts with TRF1 and is essential for ALT-associated PML bodies assembly in U2OS cells
Keywords: Alternative lengthening of telomeres; ALT-associated PML bodies; TRF1; PML3
Human PinX1 Mediates TRF1 Accumulation in Nucleolus and Enhances TRF1 Binding to Telomeres
Keywords: hPinX1, human PinX1; HA, hemagglutinin; DAPI, 4′,6-diamidino-2-phenylindole; IP, immunoprecipitation; ChIP, chromatin immunoprecipitation; NoLS, nucleolus localization signalhuman PinX1; TRF1; nucleolus; telomere; ALT
Modulation of telomere shelterin by TFR1 and TRF2 interacts with telomerase to maintain the telomere length in non-small cell lung cancer
Keywords: TRF1; TRF2; Telomere; Telomerase; Lung cancer
Up-regulation of telomere-binding TRF1, TRF2 related to reactive oxygen species induced by As2O3 in MGC-803 cells
Keywords: Apoptosis; TRF1; TRF2; Reactive oxygen species; Arsenic trioxide; Telomeric state;
Characterization of the telomere complex, TERF1 and TERF2 genes in muntjac species with fusion karyotypes
Keywords: Muntiacus muntjak vaginalis; M. reveesi; Telomerase; Telomere repeat binding factors; TRF1; TRF2;